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The map label for this gene is hlgA [H]

Identifier: 150394929

GI number: 150394929

Start: 2579205

End: 2580170

Strand: Direct

Name: hlgA [H]

Synonym: SaurJH1_2493

Alternate gene names: 150394929

Gene position: 2579205-2580170 (Clockwise)

Preceding gene: 150394928

Following gene: 150394930

Centisome position: 88.74

GC content: 32.09

Gene sequence:

>966_bases
ATGAACTTAAAATTAAATAGAAAGAAAGTGATTTCTATGATTAAAAATAAAATATTAACAGCAACTTTAGCAGTTGGTTT
AATAGCCCCTTTAGCCAATCCATTTATAGAAATTTCTAAAGCAGAAAATAAGATAGAAGATATCGGTCAAGGTGCAGAAA
TCATCAAAAGAACACAAGACATTACTAGCAAACGATTAGCTATAACTCAAAACATTCAATTTGATTTTGTAAAAGATAAA
AAATATAACAAAGATGCCCTAGTTGTTAAGATGCAAGGCTTCATCAGCTCTAGAACAACATATTCAGACTTAAAAAAATA
TCCATATATTAAAAGAATGATATGGCCATTTCAATATAATATCAGTTTGAAAACGAAAGACTCTAATGTTGATTTAATCA
ATTATCTTCCTAAAAATAAAATTGATTCAGCAGATGTTAGTCAGAAATTAGGCTATAATATCGGCGGAAACTTCCAATCA
GCGCCATCAATCGGAGGCAGTGGCTCATTCAACTACTCTAAAACAATTAGTTATAATCAAAAAAACTATGTTACTGAAGT
AGAAAGTCAGAACTCTAAAGGTGTTAAATGGGGAGTGAAAGCAAATTCATTTGTTACACCGAATGGTCAAGTATCTGCAT
ATGATCAATACTTATTTGCACAAGACCCAACTGGTCCAGCAGCAAGAGACTATTTCGTCCCAGATAATCAATTACCTCCT
TTAATTCAAAGTGGCTTTAATCCATCATTTATTACAACATTGTCACACGAAAGAGGTAAAGGTGATAAAAGCGAGTTTGA
AATCACTTACGGCAGAAACATGGATGCTACATATGCTTACGTGACAAGACATCGTTTAGCCGTTGATAGAAAACATGATG
CTTTTAAAAACCGAAACGTTACAGTTAAATATGAAGTGAACTGGAAAACACATGAAGTAAAAATTAAAAGCATCACACCT
AAGTAA

Upstream 100 bases:

>100_bases
ATTTAACAATGCTAAAAATGTCTCTTCAATACATGTTGATAGTAATTAACTTTTAACGAACAGTTAATTCGAAAACGCTT
ACAAATGGATTATTATATAT

Downstream 100 bases:

>100_bases
ACAGTTCAATCATTTTAAAAAATCCTGGGACACTTCATACTTGTCTCAGGATTTTTTAACATATTGAATCAGCCTCATAA
CATTAAATTAATTTATCGTA

Product: beta-channel forming cytolysin

Products: NA

Alternate protein names: H-gamma-2; H-gamma-II [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MNLKLNRKKVISMIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGAEIIKRTQDITSKRLAITQNIQFDFVKDK
KYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMIWPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQS
APSIGGSGSFNYSKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARDYFVPDNQLPP
LIQSGFNPSFITTLSHERGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNVTVKYEVNWKTHEVKIKSITP
K

Sequences:

>Translated_321_residues
MNLKLNRKKVISMIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGAEIIKRTQDITSKRLAITQNIQFDFVKDK
KYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMIWPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQS
APSIGGSGSFNYSKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARDYFVPDNQLPP
LIQSGFNPSFITTLSHERGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNVTVKYEVNWKTHEVKIKSITP
K
>Mature_321_residues
MNLKLNRKKVISMIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGAEIIKRTQDITSKRLAITQNIQFDFVKDK
KYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMIWPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQS
APSIGGSGSFNYSKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARDYFVPDNQLPP
LIQSGFNPSFITTLSHERGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNVTVKYEVNWKTHEVKIKSITP
K

Specific function: Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aerolysin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003963
- InterPro:   IPR001340
- InterPro:   IPR016183 [H]

Pfam domain/function: PF07968 Leukocidin [H]

EC number: NA

Molecular weight: Translated: 36382; Mature: 36382

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKLNRKKVISMIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGAEIIKRTQD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCHHHHHHHHH
ITSKRLAITQNIQFDFVKDKKYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMIWPFQYN
HHHHEEEEEECCEEEEEECCCCCCCEEEEEEECHHCCCCCHHHHHHCCHHHHEECCEEEE
ISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQSAPSIGGSGSFNYSKTISYNQ
EEEEECCCCCEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECC
KNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARDYFVPDNQLPP
CCEEEEECCCCCCCEEEECCCCCEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCH
LIQSGFNPSFITTLSHERGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNV
HHHCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCEEHHHHHHHHHHCCCHHHHCCCCE
TVKYEVNWKTHEVKIKSITPK
EEEEEECCEEEEEEEEECCCC
>Mature Secondary Structure
MNLKLNRKKVISMIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGAEIIKRTQD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCHHHHHHHHH
ITSKRLAITQNIQFDFVKDKKYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMIWPFQYN
HHHHEEEEEECCEEEEEECCCCCCCEEEEEEECHHCCCCCHHHHHHCCHHHHEECCEEEE
ISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQSAPSIGGSGSFNYSKTISYNQ
EEEEECCCCCEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECC
KNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARDYFVPDNQLPP
CCEEEEECCCCCCCEEEECCCCCEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCH
LIQSGFNPSFITTLSHERGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNV
HHHCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCEEHHHHHHHHHHCCCHHHHCCCCE
TVKYEVNWKTHEVKIKSITPK
EEEEEECCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA