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The map label for this gene is capD [H]

Identifier: 150010379

GI number: 150010379

Start: 4648684

End: 4650624

Strand: Direct

Name: capD [H]

Synonym: BDI_3816

Alternate gene names: 150010379

Gene position: 4648684-4650624 (Clockwise)

Preceding gene: 150010378

Following gene: 150010384

Centisome position: 96.62

GC content: 55.33

Gene sequence:

>1941_bases
ATGATGAACCTTTTTTCTAAACTCTCAACGTGGTATTTCTCAAGGAAAGCGTTGCCGTATTGGAGCATTATCCTGTTGGA
TTGCTTGGTGATCCTGTTTTCAGGCTTGCTGGTATATGCCTTGAATAACGGGATCTTCGCCACGATGGGCATCTTTTGGC
ACCTGTCGCTCACGTGGGGTGTTTGCCTAGTGCCTTATCTGGTGGGCTTTAGGCTGTTCCGTACGTATTCGGGCATCATT
CGTTACTCTTCCTTCGTGGATTTGCAACGGGTGGGCTTCGCCGTGCTGTTCGGTGTGGTTTGCGTGGTGACCTTCCAAGA
GTTTACGGATTTTTCGCCTTACTTGGTGTATATCCGTAAACGAGACCTTGTGCTATCCTCCCTGCTGGCGATGAGCTTGA
TGTGGGCGATGCGTGTGTTCGTGAAGTATTTCTACGTGACAACCTTCCGTCAGTCGAAGGCTGAGCGTGCCTTTATCTTC
GGCGTGAAGCAGGGCGGTATCAGTTTGGCGAAGAGCATCCAGAACCAAGATCCCGCACAGTACGTGCTGGCAGGCTTCGT
CTCGGAGGCCGGGAACATGCAGAATCGTATATTGATGGGAGTGCGTGTGTACCCTTTCGATGAGGAGCTGATCGATGCGA
TGCGCCGGGAGCGGGCGACGATCCTTTTCGTCTCCCCCTTGAAGAGCGACTCCATCCGGGAACAGCCGGATATGGTGGCC
CGTTTGGCGGAGGCGGGGATCAAGATCTACGTGACCCCGGCGGCGCAAGAATGGGATGGCAGGAGCGATTTGACGCATAC
ACAACTCCGGAAGGTTGAGATCGAGGATCTGCTTCCCCGGGAAAAGATAGAGATAGACATGGAGGCGGTGGGCCGCTTGC
TTCGTGGTCAACGCATCCTGATAACGGGAGCCGCCGGCAGCATCGGTGGCGAGATGGTGCGCCAGATCGCCTCGTTCACT
CCGGATCGCTTGATCTTGGTAGATCAGGCGGAGACCCCCTTGCACGACATCCGCTTGATGATGGCGAGGGATTGGCGGGA
TATCAACGCCTATACCTTGGTGGCGGACATCGCTAACAAGTCTCGCATGGAGGAGATCTTCTCGGAGCATCGCCCCGCCT
ATGTATTCCATGCGGCGGCCTATAAGCACGTTCCGATGATGGAGGATAATCCTTGCGAGAGTGTGGGTAACAACGTGGAC
GGTACCCGTGTGATCGCCGACTTGGCCGTGAAGTATGGCACGAGGAAGTTCGTGATGATCTCCACGGACAAGGCGGTGAA
TCCTACGAATGTGATGGGTTGCTCGAAGCGCATCTGCGAGATTTACGTGCAGAGCCTCGACAAGGCGATCAAGGAGGGCC
ATGTGGAAGGCGTGACGCAGTTCGTTACGACCCGCTTCGGCAACGTGCTGGGTTCTAACGGCTCCGTGATCCCATTGTTC
CGTGAACAGATTGCCAAGGGCGGTCCCGTGACAGTGACGCATCCGGATATCATCCGTTTCTTCATGCTGATCCCGGAGGC
CTGCCGGTTGGTATTGGAGGCGGGTACGATGGGTAACGGTGGGGAGATCTTCGTCTTCGACATGGGCAAGCCCGTGCGTA
TCATCGACTTGGCGAAACGTATGATTCAGCTTTCGGGCGCCAAGAACGTAGAGGTCCGGTTTACGGGTCTTCGTGCCGGC
GAGAAGCTGTACGAGGAGGTACTGAACGACGAGGAGATCACGCTGCCTACCTTCCATCCGAAGATCAAGATCGCCAAGGT
ACGGGAGTACGATTATGATACGGTTTGCCAAGATATAGATGAACTCGTCGGCCTAGGCCGCTCGAGGGACGATATGGCCA
TCGTGGGCAAGATGAAGGCGATCGTCCCCGAGTTTAAGAGCCGGCACTCCAAGTACGAGGTCTTGGATAAGGCGCTAGAA
AGCGCAAGCACTGATGCCTAA

Upstream 100 bases:

>100_bases
GTACTAACTGCTCCCGAATCCTCTTCGACCGACTACCGAAGATGGCATGCCGGTGAGGTGGAGGGCTTGCCCCAGCTGAC
ATGAACCAAAAATTTTATTC

Downstream 100 bases:

>100_bases
GGCCCCGGCGATGGTGGTGGCTATGGCGATGACTACTTTGATGATTACGCTCCAAACGTTGGTTTTCTTCTTTTCACTCA
TTTAAATTTGTTTTATAAGG

Product: putative nucleotide-diphosphate sugar epimerase

Products: dTDP-4-dehydro-6-deoxy-D-glucose; H2O [C]

Alternate protein names: NA

Number of amino acids: Translated: 646; Mature: 646

Protein sequence:

>646_residues
MMNLFSKLSTWYFSRKALPYWSIILLDCLVILFSGLLVYALNNGIFATMGIFWHLSLTWGVCLVPYLVGFRLFRTYSGII
RYSSFVDLQRVGFAVLFGVVCVVTFQEFTDFSPYLVYIRKRDLVLSSLLAMSLMWAMRVFVKYFYVTTFRQSKAERAFIF
GVKQGGISLAKSIQNQDPAQYVLAGFVSEAGNMQNRILMGVRVYPFDEELIDAMRRERATILFVSPLKSDSIREQPDMVA
RLAEAGIKIYVTPAAQEWDGRSDLTHTQLRKVEIEDLLPREKIEIDMEAVGRLLRGQRILITGAAGSIGGEMVRQIASFT
PDRLILVDQAETPLHDIRLMMARDWRDINAYTLVADIANKSRMEEIFSEHRPAYVFHAAAYKHVPMMEDNPCESVGNNVD
GTRVIADLAVKYGTRKFVMISTDKAVNPTNVMGCSKRICEIYVQSLDKAIKEGHVEGVTQFVTTRFGNVLGSNGSVIPLF
REQIAKGGPVTVTHPDIIRFFMLIPEACRLVLEAGTMGNGGEIFVFDMGKPVRIIDLAKRMIQLSGAKNVEVRFTGLRAG
EKLYEEVLNDEEITLPTFHPKIKIAKVREYDYDTVCQDIDELVGLGRSRDDMAIVGKMKAIVPEFKSRHSKYEVLDKALE
SASTDA

Sequences:

>Translated_646_residues
MMNLFSKLSTWYFSRKALPYWSIILLDCLVILFSGLLVYALNNGIFATMGIFWHLSLTWGVCLVPYLVGFRLFRTYSGII
RYSSFVDLQRVGFAVLFGVVCVVTFQEFTDFSPYLVYIRKRDLVLSSLLAMSLMWAMRVFVKYFYVTTFRQSKAERAFIF
GVKQGGISLAKSIQNQDPAQYVLAGFVSEAGNMQNRILMGVRVYPFDEELIDAMRRERATILFVSPLKSDSIREQPDMVA
RLAEAGIKIYVTPAAQEWDGRSDLTHTQLRKVEIEDLLPREKIEIDMEAVGRLLRGQRILITGAAGSIGGEMVRQIASFT
PDRLILVDQAETPLHDIRLMMARDWRDINAYTLVADIANKSRMEEIFSEHRPAYVFHAAAYKHVPMMEDNPCESVGNNVD
GTRVIADLAVKYGTRKFVMISTDKAVNPTNVMGCSKRICEIYVQSLDKAIKEGHVEGVTQFVTTRFGNVLGSNGSVIPLF
REQIAKGGPVTVTHPDIIRFFMLIPEACRLVLEAGTMGNGGEIFVFDMGKPVRIIDLAKRMIQLSGAKNVEVRFTGLRAG
EKLYEEVLNDEEITLPTFHPKIKIAKVREYDYDTVCQDIDELVGLGRSRDDMAIVGKMKAIVPEFKSRHSKYEVLDKALE
SASTDA
>Mature_646_residues
MMNLFSKLSTWYFSRKALPYWSIILLDCLVILFSGLLVYALNNGIFATMGIFWHLSLTWGVCLVPYLVGFRLFRTYSGII
RYSSFVDLQRVGFAVLFGVVCVVTFQEFTDFSPYLVYIRKRDLVLSSLLAMSLMWAMRVFVKYFYVTTFRQSKAERAFIF
GVKQGGISLAKSIQNQDPAQYVLAGFVSEAGNMQNRILMGVRVYPFDEELIDAMRRERATILFVSPLKSDSIREQPDMVA
RLAEAGIKIYVTPAAQEWDGRSDLTHTQLRKVEIEDLLPREKIEIDMEAVGRLLRGQRILITGAAGSIGGEMVRQIASFT
PDRLILVDQAETPLHDIRLMMARDWRDINAYTLVADIANKSRMEEIFSEHRPAYVFHAAAYKHVPMMEDNPCESVGNNVD
GTRVIADLAVKYGTRKFVMISTDKAVNPTNVMGCSKRICEIYVQSLDKAIKEGHVEGVTQFVTTRFGNVLGSNGSVIPLF
REQIAKGGPVTVTHPDIIRFFMLIPEACRLVLEAGTMGNGGEIFVFDMGKPVRIIDLAKRMIQLSGAKNVEVRFTGLRAG
EKLYEEVLNDEEITLPTFHPKIKIAKVREYDYDTVCQDIDELVGLGRSRDDMAIVGKMKAIVPEFKSRHSKYEVLDKALE
SASTDA

Specific function: Required for the biosynthesis of type 1 capsular polysaccharide [H]

COG id: COG1086

COG function: function code MG; Predicted nucleoside-diphosphate sugar epimerases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR003869 [H]

Pfam domain/function: PF02719 Polysacc_synt_2 [H]

EC number: 4.2.1.46 [C]

Molecular weight: Translated: 72919; Mature: 72919

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNLFSKLSTWYFSRKALPYWSIILLDCLVILFSGLLVYALNNGIFATMGIFWHLSLTWG
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHH
VCLVPYLVGFRLFRTYSGIIRYSSFVDLQRVGFAVLFGVVCVVTFQEFTDFSPYLVYIRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEH
RDLVLSSLLAMSLMWAMRVFVKYFYVTTFRQSKAERAFIFGVKQGGISLAKSIQNQDPAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCCCHHH
YVLAGFVSEAGNMQNRILMGVRVYPFDEELIDAMRRERATILFVSPLKSDSIREQPDMVA
HHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHH
RLAEAGIKIYVTPAAQEWDGRSDLTHTQLRKVEIEDLLPREKIEIDMEAVGRLLRGQRIL
HHHHCCEEEEEECCCCCCCCCCCCCHHHHHHEEHHHCCCCHHEEECHHHHHHHHCCCEEE
ITGAAGSIGGEMVRQIASFTPDRLILVDQAETPLHDIRLMMARDWRDINAYTLVADIANK
EEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEHHHHHHH
SRMEEIFSEHRPAYVFHAAAYKHVPMMEDNPCESVGNNVDGTRVIADLAVKYGTRKFVMI
HHHHHHHHCCCCEEEEEHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCEEEEE
STDKAVNPTNVMGCSKRICEIYVQSLDKAIKEGHVEGVTQFVTTRFGNVLGSNGSVIPLF
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEHHH
REQIAKGGPVTVTHPDIIRFFMLIPEACRLVLEAGTMGNGGEIFVFDMGKPVRIIDLAKR
HHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHH
MIQLSGAKNVEVRFTGLRAGEKLYEEVLNDEEITLPTFHPKIKIAKVREYDYDTVCQDID
HHHHCCCCCEEEEEECCCCHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCHHHHHHHHH
ELVGLGRSRDDMAIVGKMKAIVPEFKSRHSKYEVLDKALESASTDA
HHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMNLFSKLSTWYFSRKALPYWSIILLDCLVILFSGLLVYALNNGIFATMGIFWHLSLTWG
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHH
VCLVPYLVGFRLFRTYSGIIRYSSFVDLQRVGFAVLFGVVCVVTFQEFTDFSPYLVYIRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEH
RDLVLSSLLAMSLMWAMRVFVKYFYVTTFRQSKAERAFIFGVKQGGISLAKSIQNQDPAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCCCHHH
YVLAGFVSEAGNMQNRILMGVRVYPFDEELIDAMRRERATILFVSPLKSDSIREQPDMVA
HHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHH
RLAEAGIKIYVTPAAQEWDGRSDLTHTQLRKVEIEDLLPREKIEIDMEAVGRLLRGQRIL
HHHHCCEEEEEECCCCCCCCCCCCCHHHHHHEEHHHCCCCHHEEECHHHHHHHHCCCEEE
ITGAAGSIGGEMVRQIASFTPDRLILVDQAETPLHDIRLMMARDWRDINAYTLVADIANK
EEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEHHHHHHH
SRMEEIFSEHRPAYVFHAAAYKHVPMMEDNPCESVGNNVDGTRVIADLAVKYGTRKFVMI
HHHHHHHHCCCCEEEEEHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCEEEEE
STDKAVNPTNVMGCSKRICEIYVQSLDKAIKEGHVEGVTQFVTTRFGNVLGSNGSVIPLF
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEHHH
REQIAKGGPVTVTHPDIIRFFMLIPEACRLVLEAGTMGNGGEIFVFDMGKPVRIIDLAKR
HHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHH
MIQLSGAKNVEVRFTGLRAGEKLYEEVLNDEEITLPTFHPKIKIAKVREYDYDTVCQDID
HHHHCCCCCEEEEEECCCCHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCHHHHHHHHH
ELVGLGRSRDDMAIVGKMKAIVPEFKSRHSKYEVLDKALESASTDA
HHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NAD. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.093 {dTDPglucose}} [C]

Substrates: dTDPglucose [C]

Specific reaction: dTDPglucose --> dTDP-4-dehydro-6-deoxy-D-glucose + H2O [C]

General reaction: Elimination (of H2O C-O bond cleavage [C]

Inhibitor: p-Chloromercuribenzoate; TMP [C]

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961465 [H]