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The map label for this gene is mro [H]

Identifier: 150010316

GI number: 150010316

Start: 4571361

End: 4572509

Strand: Direct

Name: mro [H]

Synonym: BDI_3750

Alternate gene names: 150010316

Gene position: 4571361-4572509 (Clockwise)

Preceding gene: 150010309

Following gene: 150010320

Centisome position: 95.01

GC content: 48.13

Gene sequence:

>1149_bases
ATGAAAAAACTTTGTTTTGCGGTCATGGCAATGTGTATGTTATTGTCATGCGGAGGTAAGAATGAGAAGGAGGCGGCTAC
GGAAGAGGCCACTCTTTCTGGTTTGATGAAGTCGGATTTTGTATCTGAGGTAGATGGTAAGCCGACTGCTTTGTATGTGT
TGAAGAATAAGAAAGGGGCTGAGGCTTGCGTAACGAATTGGGGCGGACGCTTGGTTTCCGTGATGGTGCCTGATAAGAAC
GGTAAGATGACGGACGTGGTGCTGGGTTACGATAATATCGCGCAATACGTGGCGAACCCAGACATGAATTATGGTGCCTT
GATCGGACGCTATGGCAACCGCATCGCGAATAGTAAGTTTACGTTGGACGGAACGGAGTATCAACTTCCGCAGAATAATA
ACGGCCATTGCTTGCATGGAGGTCCGAAGGGATATCATGCGGTAGTTTGGGACGCGAAACAGGTCGATGACCAAACCTTG
GAGTTGACTTATCTATCGAAAGACGGTGAGGCAGGTTTCCCCGGTAATCTGGATATCAAGGTGATCTATAAGTTGACGGA
TGATAACGCCGTTGATATTAAGTACGAGGCTACGACGGATAAACTTACTGTCGTGAATTTGACAAACCATAGTTATTTCA
ATCTTTCCGGTGTCCCCGGCTCGCAAATCATGGATCATACGATCATGATCGATGCGGATACATATAACCCGGTGGACGAG
ACTTTGATCCCGACCGGTATCGAACCCGTGGAAGGCACACCGATGGATCTTCGCAAACCGGTAGTGGTAGGCGCTGATAT
CGACAATCCGTTTACGCAATTGGTTTATGGTGGTGGTTACGATCATAACTGGATTTTGAACGCCGCCGGCGATATCAATA
AGGTAGCCGCTAAAGTTGTATCTCCGACAAGCGGTATCGTTATGGAAGTTTACACCAATGAGCCGGGTCTTCAATTCTAT
GCCGGCAACTCAATGACGAAAGCGGGTGATAAAGGCAAGTTAGGTGTGGTTTACCCGCATCGTGGCGCTCTATGTCTGGA
GACTCAACATTACCCGGATAGCCCGAACCAGCCGGCATTCCCGAGCGTAGTGCTTCGTCCGGGCGAGAAATATACGAGTG
AGTGTATTTATAAGTTCTCGGTAGAGTAA

Upstream 100 bases:

>100_bases
TAAGGATTCCCGAGAAAATGCGTAAGGATATTGGACCTCATGTGGATAGAATGCGTATCTTTGCCCGAAGAATAACATTT
ATTAATTTTAAAGGAAAGAG

Downstream 100 bases:

>100_bases
ATAAGGAAGAAAGTTCCGGATTTGGAAATATCCACATAATGGTGAGGCGTATATACATAAATAGGATGTATATGCGCCTC
TCTTTTTTACTCACGGAAGC

Product: putative aldose 1-epimerase

Products: NA

Alternate protein names: Galactose mutarotase; Type-1 mutarotase [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MKKLCFAVMAMCMLLSCGGKNEKEAATEEATLSGLMKSDFVSEVDGKPTALYVLKNKKGAEACVTNWGGRLVSVMVPDKN
GKMTDVVLGYDNIAQYVANPDMNYGALIGRYGNRIANSKFTLDGTEYQLPQNNNGHCLHGGPKGYHAVVWDAKQVDDQTL
ELTYLSKDGEAGFPGNLDIKVIYKLTDDNAVDIKYEATTDKLTVVNLTNHSYFNLSGVPGSQIMDHTIMIDADTYNPVDE
TLIPTGIEPVEGTPMDLRKPVVVGADIDNPFTQLVYGGGYDHNWILNAAGDINKVAAKVVSPTSGIVMEVYTNEPGLQFY
AGNSMTKAGDKGKLGVVYPHRGALCLETQHYPDSPNQPAFPSVVLRPGEKYTSECIYKFSVE

Sequences:

>Translated_382_residues
MKKLCFAVMAMCMLLSCGGKNEKEAATEEATLSGLMKSDFVSEVDGKPTALYVLKNKKGAEACVTNWGGRLVSVMVPDKN
GKMTDVVLGYDNIAQYVANPDMNYGALIGRYGNRIANSKFTLDGTEYQLPQNNNGHCLHGGPKGYHAVVWDAKQVDDQTL
ELTYLSKDGEAGFPGNLDIKVIYKLTDDNAVDIKYEATTDKLTVVNLTNHSYFNLSGVPGSQIMDHTIMIDADTYNPVDE
TLIPTGIEPVEGTPMDLRKPVVVGADIDNPFTQLVYGGGYDHNWILNAAGDINKVAAKVVSPTSGIVMEVYTNEPGLQFY
AGNSMTKAGDKGKLGVVYPHRGALCLETQHYPDSPNQPAFPSVVLRPGEKYTSECIYKFSVE
>Mature_382_residues
MKKLCFAVMAMCMLLSCGGKNEKEAATEEATLSGLMKSDFVSEVDGKPTALYVLKNKKGAEACVTNWGGRLVSVMVPDKN
GKMTDVVLGYDNIAQYVANPDMNYGALIGRYGNRIANSKFTLDGTEYQLPQNNNGHCLHGGPKGYHAVVWDAKQVDDQTL
ELTYLSKDGEAGFPGNLDIKVIYKLTDDNAVDIKYEATTDKLTVVNLTNHSYFNLSGVPGSQIMDHTIMIDADTYNPVDE
TLIPTGIEPVEGTPMDLRKPVVVGADIDNPFTQLVYGGGYDHNWILNAAGDINKVAAKVVSPTSGIVMEVYTNEPGLQFY
AGNSMTKAGDKGKLGVVYPHRGALCLETQHYPDSPNQPAFPSVVLRPGEKYTSECIYKFSVE

Specific function: Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose [H]

COG id: COG2017

COG function: function code G; Galactose mutarotase and related enzymes

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldose epimerase family [H]

Homologues:

Organism=Homo sapiens, GI20270355, Length=319, Percent_Identity=44.8275862068966, Blast_Score=267, Evalue=1e-71,
Organism=Escherichia coli, GI1786971, Length=349, Percent_Identity=39.541547277937, Blast_Score=235, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI17557428, Length=340, Percent_Identity=32.3529411764706, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI115533334, Length=340, Percent_Identity=32.3529411764706, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6319493, Length=334, Percent_Identity=32.0359281437126, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6322004, Length=339, Percent_Identity=29.2035398230088, Blast_Score=116, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6324399, Length=352, Percent_Identity=30.1136363636364, Blast_Score=105, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24583720, Length=340, Percent_Identity=39.4117647058824, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24668278, Length=337, Percent_Identity=37.9821958456973, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24659048, Length=341, Percent_Identity=39.5894428152493, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24668282, Length=337, Percent_Identity=37.0919881305638, Blast_Score=221, Evalue=7e-58,
Organism=Drosophila melanogaster, GI24641876, Length=343, Percent_Identity=31.7784256559767, Blast_Score=175, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018052
- InterPro:   IPR008183
- InterPro:   IPR015443
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.3 [H]

Molecular weight: Translated: 41535; Mature: 41535

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00545 ALDOSE_1_EPIMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLCFAVMAMCMLLSCGGKNEKEAATEEATLSGLMKSDFVSEVDGKPTALYVLKNKKGA
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
EACVTNWGGRLVSVMVPDKNGKMTDVVLGYDNIAQYVANPDMNYGALIGRYGNRIANSKF
HHHHCCCCCEEEEEEEECCCCCEEEEEECHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEE
TLDGTEYQLPQNNNGHCLHGGPKGYHAVVWDAKQVDDQTLELTYLSKDGEAGFPGNLDIK
EECCCEEECCCCCCCEEECCCCCCCEEEEECHHHCCCCEEEEEEEECCCCCCCCCCCEEE
VIYKLTDDNAVDIKYEATTDKLTVVNLTNHSYFNLSGVPGSQIMDHTIMIDADTYNPVDE
EEEEECCCCEEEEEEECCCCEEEEEEECCCCEEEECCCCCHHHCCEEEEEECCCCCCCCC
TLIPTGIEPVEGTPMDLRKPVVVGADIDNPFTQLVYGGGYDHNWILNAAGDINKVAAKVV
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHEEECCCCCCCEEEECCCCHHHHHHHHC
SPTSGIVMEVYTNEPGLQFYAGNSMTKAGDKGKLGVVYPHRGALCLETQHYPDSPNQPAF
CCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCC
PSVVLRPGEKYTSECIYKFSVE
CEEEECCCCHHCCCEEEEEECC
>Mature Secondary Structure
MKKLCFAVMAMCMLLSCGGKNEKEAATEEATLSGLMKSDFVSEVDGKPTALYVLKNKKGA
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
EACVTNWGGRLVSVMVPDKNGKMTDVVLGYDNIAQYVANPDMNYGALIGRYGNRIANSKF
HHHHCCCCCEEEEEEEECCCCCEEEEEECHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEE
TLDGTEYQLPQNNNGHCLHGGPKGYHAVVWDAKQVDDQTLELTYLSKDGEAGFPGNLDIK
EECCCEEECCCCCCCEEECCCCCCCEEEEECHHHCCCCEEEEEEEECCCCCCCCCCCEEE
VIYKLTDDNAVDIKYEATTDKLTVVNLTNHSYFNLSGVPGSQIMDHTIMIDADTYNPVDE
EEEEECCCCEEEEEEECCCCEEEEEEECCCCEEEECCCCCHHHCCEEEEEECCCCCCCCC
TLIPTGIEPVEGTPMDLRKPVVVGADIDNPFTQLVYGGGYDHNWILNAAGDINKVAAKVV
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHEEECCCCCCCEEEECCCCHHHHHHHHC
SPTSGIVMEVYTNEPGLQFYAGNSMTKAGDKGKLGVVYPHRGALCLETQHYPDSPNQPAF
CCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCC
PSVVLRPGEKYTSECIYKFSVE
CEEEECCCCHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3012466; 3531172 [H]