Click here to switch to the map view.

The map label for this gene is yisQ [H]

Identifier: 150010276

GI number: 150010276

Start: 4524084

End: 4525460

Strand: Direct

Name: yisQ [H]

Synonym: BDI_3705

Alternate gene names: 150010276

Gene position: 4524084-4525460 (Clockwise)

Preceding gene: 150010273

Following gene: 150010277

Centisome position: 94.03

GC content: 47.49

Gene sequence:

>1377_bases
ATGGACATGTATAGACTATTCCGTGCCCCGAGAGGGCTGAGAGGCAAATTATTTAAATTAACAGGGCCTATCTTTCTGGA
AACCTTGCTGATGTTGACTTTAGGCGTGGTGGATACGCTTATGTTGAGCCATCATTCCGATAATGCGGTGGCAGCGGTAG
GTGTGGTTAATCAATTGCTGAACATGGTATTTCTGCTGTTCAATATTACCACGACCGGAACGTCTGTCATGTGCGCCCTC
TATTTTGGGGCGAAAGATAATAAGAGTTTTATTCAGGTGTTAGGAACCTCCTTGTTGTTTAACGCCGGCGTAGGTTGCTT
GATCAGCTTGATGCTTTTCTTGTTCGGTAGGGAGATGTTGGTCCTGATGGATATCCGTCCGGATCTGATGCCGGACGCTG
AGACTTATATGCACATTGTCGGAGGGTTCGGCTTCTTCCAAGCGGTTAGTTTTACGATATCGGCGGTGCTCCGTGCGGCG
AACAAGCCGAATTACGCGATGCAGGTGACCTTGCTGATCAATGTATTGAATGTGTTTGGAAATTATGCATTGATATTTGG
CCATTTCGGTTTTCCTGCCCTCGGTGTACAAGGAGCGGCTATCTCTACCTCTGTTTGCCGGGGAGTGGCGATGACACTTT
TGTTTATCATGCTGTTCAAGCGGTTGGTGCCTCGTATCCCTTTGGCTTATTTCCGTCCGTTCCCGTTTCAGAAGTTGAGA
GACGTGTTGAAGATCGGTTTGCCTTCGGCAGCGGAACAAATCTCGTATGATGCCTCGCAGGTGACGATTGTCTACTTTAT
CAATATGCTGGGTAATGAGTACTTGACAGCTCGTGTTTATGTGATGAATATCGTAATAATCGGCTATATCTTTTCTTTGT
CGATCGCACAAGCTACTTCTATTTGTACCGGCAATTTGGTGGGCGCGAGGAAGAAGCAAGCCGCTTATTTATTGAGTTGG
TATGCTTGGAGGAGGTCATTGCTGATTACGCTGGTCGCTAGTACCGGGGTTTATCTGCTGGGACGTCCTTTATTGGGGAT
ATTCACGGAGAATCAAGCAATCATAACGATTGCGATGGGAGCCTTGCTGGTAGATGTACTCTTGGAGCAAGGGCGGGCCA
CGGTACTGCTGTTCTTATTCTGCTTGCGTTCGGTAGGCGACGTTGTGGTCCCGGTAATTATCGAGTTATTCTGTATGTGG
TTCTTTGCCGTGTTCTGCGGGTATATGTTCGGTATCGTGTTCGGATTAGGCTTAGCGGGGATGTGGTTCGCTTTTGCTTT
GGACGAGTGTTCCAGGGGAGCGGTACTCTGTTTGCGGTGGCGAACGCAGAAGTGGAAAAAGAGGATGTTAATCAAGAATC
CTGTTAATATAAGCTAA

Upstream 100 bases:

>100_bases
ACAAACTTACGGAAAATAATAGAAATAGCGAAACCTATTTAGCGTAAAGCTTTGTACCTTCGCAGACTCGTAAAAAGGTG
TTTAGGTAGAAAGCAGATCA

Downstream 100 bases:

>100_bases
AACAGGGTGTTCTTGGGAACATTTCGCCTTCTATTTGCGTCTTACTAATTACAATAGATATTTTATAAAAGATTATGATG
AAGATGAAAAAGGTATTGTT

Product: Na+ driven multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MDMYRLFRAPRGLRGKLFKLTGPIFLETLLMLTLGVVDTLMLSHHSDNAVAAVGVVNQLLNMVFLLFNITTTGTSVMCAL
YFGAKDNKSFIQVLGTSLLFNAGVGCLISLMLFLFGREMLVLMDIRPDLMPDAETYMHIVGGFGFFQAVSFTISAVLRAA
NKPNYAMQVTLLINVLNVFGNYALIFGHFGFPALGVQGAAISTSVCRGVAMTLLFIMLFKRLVPRIPLAYFRPFPFQKLR
DVLKIGLPSAAEQISYDASQVTIVYFINMLGNEYLTARVYVMNIVIIGYIFSLSIAQATSICTGNLVGARKKQAAYLLSW
YAWRRSLLITLVASTGVYLLGRPLLGIFTENQAIITIAMGALLVDVLLEQGRATVLLFLFCLRSVGDVVVPVIIELFCMW
FFAVFCGYMFGIVFGLGLAGMWFAFALDECSRGAVLCLRWRTQKWKKRMLIKNPVNIS

Sequences:

>Translated_458_residues
MDMYRLFRAPRGLRGKLFKLTGPIFLETLLMLTLGVVDTLMLSHHSDNAVAAVGVVNQLLNMVFLLFNITTTGTSVMCAL
YFGAKDNKSFIQVLGTSLLFNAGVGCLISLMLFLFGREMLVLMDIRPDLMPDAETYMHIVGGFGFFQAVSFTISAVLRAA
NKPNYAMQVTLLINVLNVFGNYALIFGHFGFPALGVQGAAISTSVCRGVAMTLLFIMLFKRLVPRIPLAYFRPFPFQKLR
DVLKIGLPSAAEQISYDASQVTIVYFINMLGNEYLTARVYVMNIVIIGYIFSLSIAQATSICTGNLVGARKKQAAYLLSW
YAWRRSLLITLVASTGVYLLGRPLLGIFTENQAIITIAMGALLVDVLLEQGRATVLLFLFCLRSVGDVVVPVIIELFCMW
FFAVFCGYMFGIVFGLGLAGMWFAFALDECSRGAVLCLRWRTQKWKKRMLIKNPVNIS
>Mature_458_residues
MDMYRLFRAPRGLRGKLFKLTGPIFLETLLMLTLGVVDTLMLSHHSDNAVAAVGVVNQLLNMVFLLFNITTTGTSVMCAL
YFGAKDNKSFIQVLGTSLLFNAGVGCLISLMLFLFGREMLVLMDIRPDLMPDAETYMHIVGGFGFFQAVSFTISAVLRAA
NKPNYAMQVTLLINVLNVFGNYALIFGHFGFPALGVQGAAISTSVCRGVAMTLLFIMLFKRLVPRIPLAYFRPFPFQKLR
DVLKIGLPSAAEQISYDASQVTIVYFINMLGNEYLTARVYVMNIVIIGYIFSLSIAQATSICTGNLVGARKKQAAYLLSW
YAWRRSLLITLVASTGVYLLGRPLLGIFTENQAIITIAMGALLVDVLLEQGRATVLLFLFCLRSVGDVVVPVIIELFCMW
FFAVFCGYMFGIVFGLGLAGMWFAFALDECSRGAVLCLRWRTQKWKKRMLIKNPVNIS

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=433, Percent_Identity=22.8637413394919, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI48994890, Length=444, Percent_Identity=24.0990990990991, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 50828; Mature: 50828

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMYRLFRAPRGLRGKLFKLTGPIFLETLLMLTLGVVDTLMLSHHSDNAVAAVGVVNQLL
CCHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
NMVFLLFNITTTGTSVMCALYFGAKDNKSFIQVLGTSLLFNAGVGCLISLMLFLFGREML
HHHHHHHHHHCCCHHHHHHEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEE
VLMDIRPDLMPDAETYMHIVGGFGFFQAVSFTISAVLRAANKPNYAMQVTLLINVLNVFG
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
NYALIFGHFGFPALGVQGAAISTSVCRGVAMTLLFIMLFKRLVPRIPLAYFRPFPFQKLR
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHH
DVLKIGLPSAAEQISYDASQVTIVYFINMLGNEYLTARVYVMNIVIIGYIFSLSIAQATS
HHHHCCCCCHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ICTGNLVGARKKQAAYLLSWYAWRRSLLITLVASTGVYLLGRPLLGIFTENQAIITIAMG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEECCCEEEHHHHH
ALLVDVLLEQGRATVLLFLFCLRSVGDVVVPVIIELFCMWFFAVFCGYMFGIVFGLGLAG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MWFAFALDECSRGAVLCLRWRTQKWKKRMLIKNPVNIS
HHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDMYRLFRAPRGLRGKLFKLTGPIFLETLLMLTLGVVDTLMLSHHSDNAVAAVGVVNQLL
CCHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
NMVFLLFNITTTGTSVMCALYFGAKDNKSFIQVLGTSLLFNAGVGCLISLMLFLFGREML
HHHHHHHHHHCCCHHHHHHEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEE
VLMDIRPDLMPDAETYMHIVGGFGFFQAVSFTISAVLRAANKPNYAMQVTLLINVLNVFG
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
NYALIFGHFGFPALGVQGAAISTSVCRGVAMTLLFIMLFKRLVPRIPLAYFRPFPFQKLR
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHH
DVLKIGLPSAAEQISYDASQVTIVYFINMLGNEYLTARVYVMNIVIIGYIFSLSIAQATS
HHHHCCCCCHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ICTGNLVGARKKQAAYLLSWYAWRRSLLITLVASTGVYLLGRPLLGIFTENQAIITIAMG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEECCCEEEHHHHH
ALLVDVLLEQGRATVLLFLFCLRSVGDVVVPVIIELFCMWFFAVFCGYMFGIVFGLGLAG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MWFAFALDECSRGAVLCLRWRTQKWKKRMLIKNPVNIS
HHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]