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The map label for this gene is btuC [H]

Identifier: 150010248

GI number: 150010248

Start: 4493709

End: 4494743

Strand: Direct

Name: btuC [H]

Synonym: BDI_3674

Alternate gene names: 150010248

Gene position: 4493709-4494743 (Clockwise)

Preceding gene: 150010247

Following gene: 150010249

Centisome position: 93.4

GC content: 45.7

Gene sequence:

>1035_bases
ATGAACAAACAAGCGCTACTTTTTTATCCGTTATTAGGGGTGGTTCTTTTGGGGCTTTTTGTTGGGGGGCTGGCGTATGG
GGCCGTACCGATTCCTTTGGATCACGTGATGGATATTTTGCTGGGGAAGGGATCTGATAAGATCGCATGGCAGAATATCG
TGTTGCAATCTCGTTTGCCTCAGGCTATAACCGCATTATTGGCGGGGGCTTCCTTGGCTACCAGCGGGTTGCTATTACAG
ACATTGTTCCGGAATCCGTTGGCGGGACCTTCCATATTGGGCATTAGTGATGGCGCTAATCTTGGAGTAGCCGCTATCAT
GCTCTATTTCGGTGGTACGTTGGGGCAGTTCACGGATTGGCCGATCAGCGGATATATGGCGGTAATCCTCGCGGCCTTTG
TGGGGGCTTGCGTGATACTGGGACTGATTATCTATTTTTCGGCAAAAGTGAAGAATAATGTCATGCTTCTGATTATCGGA
ATCATGATTGGCTATCTAGCTTCTTCGGTTATTTCTATCTTGAATTATTATTCATCTACAGACCGGGTACATGCGTTCGT
GATGTGGGGGCTTGGTAATTTTTCCGGTGTATCCTTGGAACAATTACCATTCTTTGGAACTTGTGCGTTAATCGGGCTGT
TATTAGCGATCTTGCTGATCAAGCCTTTGAATGCCTTATTATTGGGAGAAATGTATGCCGCTAATTTAGGTATCCGGATC
AAACGAACACGGATTGCGATTCTTTTGTGTACGGGAGTATTAACGGCTACAACTACTGCTTTTTGCGGCCCCATTTCCTT
TGTCGGATTAGCAGTTCCACATATCGCCCGGTTGATGTTAGGCTCTTCCAATCATAAGATGTTGGTGCCAGTTACAATGC
TGACAGGTTCCTGCGTTGCTCTTCTATGTAATATGCTGATGGTGGTACCGGGCAGTAATACGATCCTGCCATTGAATGCC
GTTACCCCTATGCTTGGGGCGCCTGTTATTATTTACGTAATCGTGAACCGGAAAAATATTCAATATTTTAATTAG

Upstream 100 bases:

>100_bases
TAACTAAGAATAATTTAGGCCATCTCTTACTGTAAGGGATGGCCTTTTTATTGATTTACCATTCACTGTATAACTCCGCT
TTTTTGTATACCTTTGCGCC

Downstream 100 bases:

>100_bases
TGGCTATGGAACGGATCCCTGTGATAAAGACAAGTGATTTAAGTATTGGGTATATATTGAAAGGCGGACAGAAAAAGCGC
GTGCATGATGCGTTGGATCT

Product: iron(III) ABC transporter permease

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MNKQALLFYPLLGVVLLGLFVGGLAYGAVPIPLDHVMDILLGKGSDKIAWQNIVLQSRLPQAITALLAGASLATSGLLLQ
TLFRNPLAGPSILGISDGANLGVAAIMLYFGGTLGQFTDWPISGYMAVILAAFVGACVILGLIIYFSAKVKNNVMLLIIG
IMIGYLASSVISILNYYSSTDRVHAFVMWGLGNFSGVSLEQLPFFGTCALIGLLLAILLIKPLNALLLGEMYAANLGIRI
KRTRIAILLCTGVLTATTTAFCGPISFVGLAVPHIARLMLGSSNHKMLVPVTMLTGSCVALLCNMLMVVPGSNTILPLNA
VTPMLGAPVIIYVIVNRKNIQYFN

Sequences:

>Translated_344_residues
MNKQALLFYPLLGVVLLGLFVGGLAYGAVPIPLDHVMDILLGKGSDKIAWQNIVLQSRLPQAITALLAGASLATSGLLLQ
TLFRNPLAGPSILGISDGANLGVAAIMLYFGGTLGQFTDWPISGYMAVILAAFVGACVILGLIIYFSAKVKNNVMLLIIG
IMIGYLASSVISILNYYSSTDRVHAFVMWGLGNFSGVSLEQLPFFGTCALIGLLLAILLIKPLNALLLGEMYAANLGIRI
KRTRIAILLCTGVLTATTTAFCGPISFVGLAVPHIARLMLGSSNHKMLVPVTMLTGSCVALLCNMLMVVPGSNTILPLNA
VTPMLGAPVIIYVIVNRKNIQYFN
>Mature_344_residues
MNKQALLFYPLLGVVLLGLFVGGLAYGAVPIPLDHVMDILLGKGSDKIAWQNIVLQSRLPQAITALLAGASLATSGLLLQ
TLFRNPLAGPSILGISDGANLGVAAIMLYFGGTLGQFTDWPISGYMAVILAAFVGACVILGLIIYFSAKVKNNVMLLIIG
IMIGYLASSVISILNYYSSTDRVHAFVMWGLGNFSGVSLEQLPFFGTCALIGLLLAILLIKPLNALLLGEMYAANLGIRI
KRTRIAILLCTGVLTATTTAFCGPISFVGLAVPHIARLMLGSSNHKMLVPVTMLTGSCVALLCNMLMVVPGSNTILPLNA
VTPMLGAPVIIYVIVNRKNIQYFN

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=285, Percent_Identity=35.0877192982456, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1790740, Length=287, Percent_Identity=30.6620209059233, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786805, Length=322, Percent_Identity=33.2298136645963, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786804, Length=266, Percent_Identity=31.203007518797, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1790741, Length=319, Percent_Identity=29.4670846394984, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786347, Length=285, Percent_Identity=29.8245614035088, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36410; Mature: 36410

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQALLFYPLLGVVLLGLFVGGLAYGAVPIPLDHVMDILLGKGSDKIAWQNIVLQSRLP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
QAITALLAGASLATSGLLLQTLFRNPLAGPSILGISDGANLGVAAIMLYFGGTLGQFTDW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCC
PISGYMAVILAAFVGACVILGLIIYFSAKVKNNVMLLIIGIMIGYLASSVISILNYYSST
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DRVHAFVMWGLGNFSGVSLEQLPFFGTCALIGLLLAILLIKPLNALLLGEMYAANLGIRI
CCEEEEEEEECCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
KRTRIAILLCTGVLTATTTAFCGPISFVGLAVPHIARLMLGSSNHKMLVPVTMLTGSCVA
EHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHH
LLCNMLMVVPGSNTILPLNAVTPMLGAPVIIYVIVNRKNIQYFN
HHHHHHEEECCCCCEEEHHHHCHHHCCCEEEEEEEECCCCCCCC
>Mature Secondary Structure
MNKQALLFYPLLGVVLLGLFVGGLAYGAVPIPLDHVMDILLGKGSDKIAWQNIVLQSRLP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
QAITALLAGASLATSGLLLQTLFRNPLAGPSILGISDGANLGVAAIMLYFGGTLGQFTDW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCC
PISGYMAVILAAFVGACVILGLIIYFSAKVKNNVMLLIIGIMIGYLASSVISILNYYSST
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DRVHAFVMWGLGNFSGVSLEQLPFFGTCALIGLLLAILLIKPLNALLLGEMYAANLGIRI
CCEEEEEEEECCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
KRTRIAILLCTGVLTATTTAFCGPISFVGLAVPHIARLMLGSSNHKMLVPVTMLTGSCVA
EHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHH
LLCNMLMVVPGSNTILPLNAVTPMLGAPVIIYVIVNRKNIQYFN
HHHHHHEEECCCCCEEEHHHHCHHHCCCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA