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The map label for this gene is atsA [H]

Identifier: 150010122

GI number: 150010122

Start: 4337602

End: 4339017

Strand: Direct

Name: atsA [H]

Synonym: BDI_3542

Alternate gene names: 150010122

Gene position: 4337602-4339017 (Clockwise)

Preceding gene: 150010121

Following gene: 150010123

Centisome position: 90.15

GC content: 45.9

Gene sequence:

>1416_bases
ATGAAAACACAATTGACTTTATGTATATCCGGGACATTGCTGCTTGTCGGAATGTCCGGTTGCGAAAAAACTCCGGAGCG
TCCTATGAATGTTGTGTATATCTTAGCGGATGATTTAGGATATGGCGATGTGGGTTGTTATGGCCAGCAGATTATCAAGA
CGCCCAATATCGATCGGATGGCGAAGGAGGGAATGTTGTTCACGCAGCATTATGCCGGATGTACGGTGAGTGCCCCTTCC
CGTTGCTCCTTGATGACCGGATTGCATACGGGACATACGCAAGTCCGGGGAAACCGGGAGATCACGCCCGAAGGCCAACA
GCCGATGCGGGAGGATACCTATACGTTGGGTAAATTAATGAAATCGGCCGGTTATACGACCGGTATCTTTGGTAAATGGG
GATTGGGAAATCCGGGCTCTGTCTCCATTCCCAATAAGATGGGCTTCGATGAGTTTTATGGGTATAATTGCCAACGGCAG
TCGCATTCCTTCTATCCGGATCATTTATGGCATAATGAGGAGAAGGTTCTTTTTCCTGAAAACGAGAACAATGCTTGCAA
GACATATTCACAAGATTTGATTCATGAGCAAGCATTGAAGTTCATCCGGGATCATAAGGAGCAACCATTCTTTGCGATGC
TTACTTATACGCTGCCTCATGCGGAATTGAATCTTCCGCATGATTCTATTTATAAGATGTACGAGAACTCATTCGAGGAG
ACTCCTTATATTGGTAAGTTTGATAAAGTGTATGGCGGTTATAACACCTCGGAGAAGCCCTTGGCCTCCTTTGCCGCCAT
GGTCTCCCGGTTGGATAAATACGTGGGGGATGTAATGGCTGAATTGAAAGAGTTAGGTTTGGATAAGAATACGATCGTGA
TTTTTACCAGCGATAACGGCCCGCATCATGAGGGTGGAGCTGATCCCGATTTTTTCAAGAGTTACGGACCTTTTAGGGGG
ATCAAACGGGATGTATATGAAGGAGGCATCCGTATACCTATGGTGGCATGGTGCCCGGGTACGATCAAGGCCGGAGCCCA
ATCGGATCATATAAGCGCATTCTGGGATGTCATGCCGACATTGGCAGAACTTACAGGTACGGTTTTGCCCGAGAAGACGG
ATGGAATCTCTTTCTTACCAACCTTGTTATCAAAGAAAGATCAACAGGCCCATGATTATTTATATTGGGAATTTCACGAG
TTGAATGGCCGGGAAGCATTACGCTCCGGTAAATGGAAACTAATCCGGCAACCGATCGTGGGTGAGACTATATTGGAACT
GTATGATTTAAGTAATGATATACACGAGGATACAAATCTGGCGGAGAAATATCCCGATAAGGTAAAAGAACTGGCAGTCT
TGATGGACAACGCCCGCATAGAGTCTCCGTACTTTAACTTTGGAAGAGAAAAGTAA

Upstream 100 bases:

>100_bases
TCGTATGGGAAGGGTTAAGGTACGGACGAACCGCTTGTCTACGAATCAGGATCAGAAGATTGTAATTGGTTTCTAACACT
TCTATTTATTTTAAAGGTAT

Downstream 100 bases:

>100_bases
ACGTGCGAGAAGAGAATAAAGTGTAGGCGTAATATCTGTTAGGTAATGATAAAAAAGGCTTTCTTTCAGCGAGAAAGCCT
TTTTTTTGTATCTTTGGCTC

Product: arylsulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MKTQLTLCISGTLLLVGMSGCEKTPERPMNVVYILADDLGYGDVGCYGQQIIKTPNIDRMAKEGMLFTQHYAGCTVSAPS
RCSLMTGLHTGHTQVRGNREITPEGQQPMREDTYTLGKLMKSAGYTTGIFGKWGLGNPGSVSIPNKMGFDEFYGYNCQRQ
SHSFYPDHLWHNEEKVLFPENENNACKTYSQDLIHEQALKFIRDHKEQPFFAMLTYTLPHAELNLPHDSIYKMYENSFEE
TPYIGKFDKVYGGYNTSEKPLASFAAMVSRLDKYVGDVMAELKELGLDKNTIVIFTSDNGPHHEGGADPDFFKSYGPFRG
IKRDVYEGGIRIPMVAWCPGTIKAGAQSDHISAFWDVMPTLAELTGTVLPEKTDGISFLPTLLSKKDQQAHDYLYWEFHE
LNGREALRSGKWKLIRQPIVGETILELYDLSNDIHEDTNLAEKYPDKVKELAVLMDNARIESPYFNFGREK

Sequences:

>Translated_471_residues
MKTQLTLCISGTLLLVGMSGCEKTPERPMNVVYILADDLGYGDVGCYGQQIIKTPNIDRMAKEGMLFTQHYAGCTVSAPS
RCSLMTGLHTGHTQVRGNREITPEGQQPMREDTYTLGKLMKSAGYTTGIFGKWGLGNPGSVSIPNKMGFDEFYGYNCQRQ
SHSFYPDHLWHNEEKVLFPENENNACKTYSQDLIHEQALKFIRDHKEQPFFAMLTYTLPHAELNLPHDSIYKMYENSFEE
TPYIGKFDKVYGGYNTSEKPLASFAAMVSRLDKYVGDVMAELKELGLDKNTIVIFTSDNGPHHEGGADPDFFKSYGPFRG
IKRDVYEGGIRIPMVAWCPGTIKAGAQSDHISAFWDVMPTLAELTGTVLPEKTDGISFLPTLLSKKDQQAHDYLYWEFHE
LNGREALRSGKWKLIRQPIVGETILELYDLSNDIHEDTNLAEKYPDKVKELAVLMDNARIESPYFNFGREK
>Mature_471_residues
MKTQLTLCISGTLLLVGMSGCEKTPERPMNVVYILADDLGYGDVGCYGQQIIKTPNIDRMAKEGMLFTQHYAGCTVSAPS
RCSLMTGLHTGHTQVRGNREITPEGQQPMREDTYTLGKLMKSAGYTTGIFGKWGLGNPGSVSIPNKMGFDEFYGYNCQRQ
SHSFYPDHLWHNEEKVLFPENENNACKTYSQDLIHEQALKFIRDHKEQPFFAMLTYTLPHAELNLPHDSIYKMYENSFEE
TPYIGKFDKVYGGYNTSEKPLASFAAMVSRLDKYVGDVMAELKELGLDKNTIVIFTSDNGPHHEGGADPDFFKSYGPFRG
IKRDVYEGGIRIPMVAWCPGTIKAGAQSDHISAFWDVMPTLAELTGTVLPEKTDGISFLPTLLSKKDQQAHDYLYWEFHE
LNGREALRSGKWKLIRQPIVGETILELYDLSNDIHEDTNLAEKYPDKVKELAVLMDNARIESPYFNFGREK

Specific function: Plays an important role in the mineralization of sulfates [H]

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4503899, Length=403, Percent_Identity=32.258064516129, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI146229331, Length=451, Percent_Identity=30.1552106430155, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI146229329, Length=451, Percent_Identity=30.1552106430155, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI6005990, Length=451, Percent_Identity=30.1552106430155, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI146229324, Length=451, Percent_Identity=30.1552106430155, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI45430057, Length=433, Percent_Identity=28.4064665127021, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI38569407, Length=349, Percent_Identity=30.3724928366762, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI38569405, Length=349, Percent_Identity=30.3724928366762, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI59797060, Length=483, Percent_Identity=27.1221532091097, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI157266309, Length=479, Percent_Identity=26.5135699373695, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI109389362, Length=482, Percent_Identity=25.3112033195021, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI58743319, Length=433, Percent_Identity=28.8683602771363, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI39930577, Length=485, Percent_Identity=24.7422680412371, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI71852586, Length=134, Percent_Identity=40.2985074626866, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI31742482, Length=137, Percent_Identity=41.6058394160584, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI71852584, Length=134, Percent_Identity=40.2985074626866, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI53831991, Length=151, Percent_Identity=36.4238410596026, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI146229327, Length=373, Percent_Identity=27.3458445040214, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI87081924, Length=419, Percent_Identity=27.6849642004773, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1790233, Length=430, Percent_Identity=28.3720930232558, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1790112, Length=443, Percent_Identity=23.2505643340858, Blast_Score=79, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI115533416, Length=471, Percent_Identity=26.1146496815287, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI115533418, Length=452, Percent_Identity=25.8849557522124, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17559078, Length=230, Percent_Identity=29.5652173913043, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17568795, Length=373, Percent_Identity=27.3458445040214, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI281363223, Length=422, Percent_Identity=29.6208530805687, Blast_Score=161, Evalue=8e-40,
Organism=Drosophila melanogaster, GI24666109, Length=413, Percent_Identity=29.0556900726392, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24666175, Length=398, Percent_Identity=31.1557788944724, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281366397, Length=382, Percent_Identity=29.3193717277487, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281366395, Length=382, Percent_Identity=29.3193717277487, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24666163, Length=382, Percent_Identity=29.3193717277487, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI21356831, Length=436, Percent_Identity=25.9174311926606, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 53236; Mature: 53236

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTQLTLCISGTLLLVGMSGCEKTPERPMNVVYILADDLGYGDVGCYGQQIIKTPNIDRM
CCCEEEEEEECEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCHHHH
AKEGMLFTQHYAGCTVSAPSRCSLMTGLHTGHTQVRGNREITPEGQQPMREDTYTLGKLM
HHCCCEEEECCCCEECCCCCCHHHHHCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHH
KSAGYTTGIFGKWGLGNPGSVSIPNKMGFDEFYGYNCQRQSHSFYPDHLWHNEEKVLFPE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHCCCCCEEECCC
NENNACKTYSQDLIHEQALKFIRDHKEQPFFAMLTYTLPHAELNLPHDSIYKMYENSFEE
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHC
TPYIGKFDKVYGGYNTSEKPLASFAAMVSRLDKYVGDVMAELKELGLDKNTIVIFTSDNG
CCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
PHHEGGADPDFFKSYGPFRGIKRDVYEGGIRIPMVAWCPGTIKAGAQSDHISAFWDVMPT
CCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
LAELTGTVLPEKTDGISFLPTLLSKKDQQAHDYLYWEFHELNGREALRSGKWKLIRQPIV
HHHHHCCCCCCCCCCHHHHHHHHCCCCCCHHCEEEEEEEECCCHHHHHCCCHHEECCCCH
GETILELYDLSNDIHEDTNLAEKYPDKVKELAVLMDNARIESPYFNFGREK
HHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTQLTLCISGTLLLVGMSGCEKTPERPMNVVYILADDLGYGDVGCYGQQIIKTPNIDRM
CCCEEEEEEECEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCHHHH
AKEGMLFTQHYAGCTVSAPSRCSLMTGLHTGHTQVRGNREITPEGQQPMREDTYTLGKLM
HHCCCEEEECCCCEECCCCCCHHHHHCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHH
KSAGYTTGIFGKWGLGNPGSVSIPNKMGFDEFYGYNCQRQSHSFYPDHLWHNEEKVLFPE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHCCCCCEEECCC
NENNACKTYSQDLIHEQALKFIRDHKEQPFFAMLTYTLPHAELNLPHDSIYKMYENSFEE
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHC
TPYIGKFDKVYGGYNTSEKPLASFAAMVSRLDKYVGDVMAELKELGLDKNTIVIFTSDNG
CCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
PHHEGGADPDFFKSYGPFRGIKRDVYEGGIRIPMVAWCPGTIKAGAQSDHISAFWDVMPT
CCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
LAELTGTVLPEKTDGISFLPTLLSKKDQQAHDYLYWEFHELNGREALRSGKWKLIRQPIV
HHHHHCCCCCCCCCCHHHHHHHHCCCCCCHHCEEEEEEEECCCHHHHHCCCHHEECCCCH
GETILELYDLSNDIHEDTNLAEKYPDKVKELAVLMDNARIESPYFNFGREK
HHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10336424 [H]