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The map label for this gene is lytS [H]

Identifier: 150009939

GI number: 150009939

Start: 4067268

End: 4068335

Strand: Direct

Name: lytS [H]

Synonym: BDI_3356

Alternate gene names: 150009939

Gene position: 4067268-4068335 (Clockwise)

Preceding gene: 150009938

Following gene: 150009940

Centisome position: 84.53

GC content: 51.31

Gene sequence:

>1068_bases
ATGAATGACACACCACAATCCCCCCCTATCAAAGGTTTGGGAAAGTTGATACACATTGCGGGATGGGGTATCCTATTCTG
TTCCCCCTTCTTCTTCACGGGGAGGGAGTCGCAAGTCACGTTCGAGGGGTATCTGCGGAGCATCATCGTGCCGCTCTCCT
TCATGCTCGTCTTCTACTTGAATTACGGGTGGCTGGTGAGGCGGTATTTGTTCAACCGCCGGACAGGGCGTTTCCTGCTG
ATCAACCTATTGCTTATCGGGAGTACGATGCTGTTCGTGCATTTCTGCATGCGCTATTTCTACCCTCCGGAGATGCATCA
TCCGGCTCGTCCGCCCCGCCCGTTGAACGAGACGGTGGGGTTCTTTCTCGTCAACGCCGTTATCTACTCCTTGGTAGCCG
GCCTTAGCGTGGCGATCAAGATGACGGACGGATGGTACCGGGTGGCGGCTATCCAGCGGGAACTGGAGAAGGAGCGTGCC
GAGGCGGAATTGCAGAACTTGAAAAGCCAGCTTAACCCGCATTTCCTGTTTAATACGTTGAATAATATCTATAGCTTGAT
AGCGTTCAGCCCGGAGAAGGCGCAGGAGGCGGTGCACGATTTGAGCCGCTTGCTTCGCTATGTCTTGTATGAGAGTAGCC
AGCCTTTTGTCCCTTTGGAGAAGGATTTCGACTTCCTTCGTAATTATGTGGAGTTGATGCGTATACGCCTGCCCAAACAT
GTGGAGCTGAAAACGAATATCGTCGCTTCCTCTCCGGGAACCTTGATCGCCCCCCTGTTGTTTATCTCCTTGGTTGAGAA
CGCATTTAAGCATGGGGTGAGCAATAATAAGCCGTCTTTCATCCATTTGGATATCCATCAGGAGGGGGCGGAGGTAGTTT
GTACTATCGTGAATAGCTATTTCCCGAAAAGCCCGGATCAAGATAAAAGTGGTTCCGGTATCGGGCTGGTGAATCTGGAG
AAACGCTTGGGGCTGCTCTATCCGGGGCATTTCTCGTTCCAATGCGGTCGGGAGGGGGATAACTATTCTTCTTATCTATC
AATTACTATAAACGAGACTGAGATATGA

Upstream 100 bases:

>100_bases
CACCTCATAGCTATGAGGCGAAGGCTCACTAGATAAGGCTACATGGCTCATATAACGGTAGGAATGACTATATTTGCGTA
GCACTAAAGAGGATAATAAG

Downstream 100 bases:

>100_bases
GATTGACTTGCGCTATTATTGACGATGAACCTTTAGCGGTTAGCTTGCTGGAAAGCTACGTCTTGAAAACTCCGTTTCTG
GATTTACAAGGGACTTATAA

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MNDTPQSPPIKGLGKLIHIAGWGILFCSPFFFTGRESQVTFEGYLRSIIVPLSFMLVFYLNYGWLVRRYLFNRRTGRFLL
INLLLIGSTMLFVHFCMRYFYPPEMHHPARPPRPLNETVGFFLVNAVIYSLVAGLSVAIKMTDGWYRVAAIQRELEKERA
EAELQNLKSQLNPHFLFNTLNNIYSLIAFSPEKAQEAVHDLSRLLRYVLYESSQPFVPLEKDFDFLRNYVELMRIRLPKH
VELKTNIVASSPGTLIAPLLFISLVENAFKHGVSNNKPSFIHLDIHQEGAEVVCTIVNSYFPKSPDQDKSGSGIGLVNLE
KRLGLLYPGHFSFQCGREGDNYSSYLSITINETEI

Sequences:

>Translated_355_residues
MNDTPQSPPIKGLGKLIHIAGWGILFCSPFFFTGRESQVTFEGYLRSIIVPLSFMLVFYLNYGWLVRRYLFNRRTGRFLL
INLLLIGSTMLFVHFCMRYFYPPEMHHPARPPRPLNETVGFFLVNAVIYSLVAGLSVAIKMTDGWYRVAAIQRELEKERA
EAELQNLKSQLNPHFLFNTLNNIYSLIAFSPEKAQEAVHDLSRLLRYVLYESSQPFVPLEKDFDFLRNYVELMRIRLPKH
VELKTNIVASSPGTLIAPLLFISLVENAFKHGVSNNKPSFIHLDIHQEGAEVVCTIVNSYFPKSPDQDKSGSGIGLVNLE
KRLGLLYPGHFSFQCGREGDNYSSYLSITINETEI
>Mature_355_residues
MNDTPQSPPIKGLGKLIHIAGWGILFCSPFFFTGRESQVTFEGYLRSIIVPLSFMLVFYLNYGWLVRRYLFNRRTGRFLL
INLLLIGSTMLFVHFCMRYFYPPEMHHPARPPRPLNETVGFFLVNAVIYSLVAGLSVAIKMTDGWYRVAAIQRELEKERA
EAELQNLKSQLNPHFLFNTLNNIYSLIAFSPEKAQEAVHDLSRLLRYVLYESSQPFVPLEKDFDFLRNYVELMRIRLPKH
VELKTNIVASSPGTLIAPLLFISLVENAFKHGVSNNKPSFIHLDIHQEGAEVVCTIVNSYFPKSPDQDKSGSGIGLVNLE
KRLGLLYPGHFSFQCGREGDNYSSYLSITINETEI

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=193, Percent_Identity=30.0518134715026, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788446, Length=194, Percent_Identity=27.319587628866, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40608; Mature: 40608

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTPQSPPIKGLGKLIHIAGWGILFCSPFFFTGRESQVTFEGYLRSIIVPLSFMLVFYL
CCCCCCCCCHHHHHHHHHHHCCHHHHHCCHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
NYGWLVRRYLFNRRTGRFLLINLLLIGSTMLFVHFCMRYFYPPEMHHPARPPRPLNETVG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
FFLVNAVIYSLVAGLSVAIKMTDGWYRVAAIQRELEKERAEAELQNLKSQLNPHFLFNTL
HHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
NNIYSLIAFSPEKAQEAVHDLSRLLRYVLYESSQPFVPLEKDFDFLRNYVELMRIRLPKH
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
VELKTNIVASSPGTLIAPLLFISLVENAFKHGVSNNKPSFIHLDIHQEGAEVVCTIVNSY
EEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
FPKSPDQDKSGSGIGLVNLEKRLGLLYPGHFSFQCGREGDNYSSYLSITINETEI
CCCCCCCCCCCCCEEEEEHHHHCCEECCCCCCEEECCCCCCCCEEEEEEEECCCC
>Mature Secondary Structure
MNDTPQSPPIKGLGKLIHIAGWGILFCSPFFFTGRESQVTFEGYLRSIIVPLSFMLVFYL
CCCCCCCCCHHHHHHHHHHHCCHHHHHCCHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
NYGWLVRRYLFNRRTGRFLLINLLLIGSTMLFVHFCMRYFYPPEMHHPARPPRPLNETVG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
FFLVNAVIYSLVAGLSVAIKMTDGWYRVAAIQRELEKERAEAELQNLKSQLNPHFLFNTL
HHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
NNIYSLIAFSPEKAQEAVHDLSRLLRYVLYESSQPFVPLEKDFDFLRNYVELMRIRLPKH
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
VELKTNIVASSPGTLIAPLLFISLVENAFKHGVSNNKPSFIHLDIHQEGAEVVCTIVNSY
EEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
FPKSPDQDKSGSGIGLVNLEKRLGLLYPGHFSFQCGREGDNYSSYLSITINETEI
CCCCCCCCCCCCCEEEEEHHHHCCEECCCCCCEEECCCCCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]