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The map label for this gene is udg [H]

Identifier: 150009822

GI number: 150009822

Start: 3921048

End: 3922298

Strand: Reverse

Name: udg [H]

Synonym: BDI_3238

Alternate gene names: 150009822

Gene position: 3922298-3921048 (Counterclockwise)

Preceding gene: 150009823

Following gene: 150009821

Centisome position: 81.52

GC content: 42.69

Gene sequence:

>1251_bases
ATGAATACAGATATAAAAATTGCCGTAGCCGGAACAGGCTATGTTGGAATGAGTATTGCCACACTGTTGGCACAACACCA
TCAGGTGATAGCCGTGGATGTCATTCCCGAAAAAGTGGAAAAGATAAACCATCAGGTGTCCCCCATACAGGATGAATATA
TTGAGAAGTATTTGGCGGAAAAACCATTGAATTTGACGGCCACCCTTAACGGCGCAACAGCTTATCGGGATGCGGACTTT
GTGGTTATTGCCGCTCCTACCAACTACGATCCGGTAAAGAACTATTTCGACACCTCACATGTGGAAGAAGTCATTGAGTT
GGTAAAAAGCGTTAATCCTAATGCCATCATGGTCATTAAGAGCACCATCCCGGTTGGTTATACCGAAAGTGTACGAAAGA
AACTTGATACGGAAAATGTTATCTTTTCACCAGAGTTCCTGCGAGAAAGCAAGGCTTTGTATGATAACCTCTATCCCAGT
CGTATCATTGTGGGCAGACCAGAAGGAGATAAACGTTTGGGCGAAGCGGCACGGACCTTTGCTGCCCTTTTACAAGAAGG
GGCGATGAAAAAAAATATTGATACACTTTTTATGGGTTTGACCGAGGCCGAGGCTGTGAAACTTTTTGCTAACACTTATT
TAGCCTTGCGTGTAAGTTATTTCAATGAACTGGATACTTACGCTGAGATGAAAGGTTTAGATACACAGGCCATCATCAAC
GGTGTGAGCCTAGACCCTCGTATCGGCACACATTACAACAATCCTTCATTCGGCTACGGAGGTTACTGTTTGCCCAAAGA
CACGAAACAGTTGCTTGCCAATTATGCGAATGTACCTGAAAACCTGATACAAGCTATTGTAGAGAGTAACCGTACCCGTA
AGGATTTCATTGCCGACAGGGTATTGAATAAAGCCGGGTATTACGATTATTACAATCGTGGAGACTTCAATCCCAATGAA
GAAAGAAAATGTGTAATCGGTGTCTATCGTCTGACAATGAAGTCAAACTCGGACAACTTCCGCCAGTCATCTATTCAAGG
AGTAATGAAGCGTATTAAAGCCAAGGGAGCAGAAGTAATTATTTATGAACCGACATTGGAAGATGGAAGTACATTTTTTG
GTAGTAAGGTGGTGAATGATCTGAATACCTTTAAAAGGCAATGTCAAGCCATTATCGCTAACCGTTATGATGCCTGCTTG
GATGATGTAAATGGCAAGGTCTATTCACGTGATGTATTTAGGAGAGACTGA

Upstream 100 bases:

>100_bases
ATAGAATATATTGTCAGTGCCAATAGAAATATGCAGTCTTGGCAAAGTAAGTGCAGATTCTTATCCCATATTCCATCTGA
CATAAATAAATCCATTCATC

Downstream 100 bases:

>100_bases
TACTTTAACTGTTTCTATATGAAAAGGCGTATATTATTCATACATAATAATTTAGGCGGAGGAGGAGCTGAAGGGGCATT
GATAGAAGTGCTGAACCATT

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MNTDIKIAVAGTGYVGMSIATLLAQHHQVIAVDVIPEKVEKINHQVSPIQDEYIEKYLAEKPLNLTATLNGATAYRDADF
VVIAAPTNYDPVKNYFDTSHVEEVIELVKSVNPNAIMVIKSTIPVGYTESVRKKLDTENVIFSPEFLRESKALYDNLYPS
RIIVGRPEGDKRLGEAARTFAALLQEGAMKKNIDTLFMGLTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLDTQAIIN
GVSLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYANVPENLIQAIVESNRTRKDFIADRVLNKAGYYDYYNRGDFNPNE
ERKCVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGAEVIIYEPTLEDGSTFFGSKVVNDLNTFKRQCQAIIANRYDACL
DDVNGKVYSRDVFRRD

Sequences:

>Translated_416_residues
MNTDIKIAVAGTGYVGMSIATLLAQHHQVIAVDVIPEKVEKINHQVSPIQDEYIEKYLAEKPLNLTATLNGATAYRDADF
VVIAAPTNYDPVKNYFDTSHVEEVIELVKSVNPNAIMVIKSTIPVGYTESVRKKLDTENVIFSPEFLRESKALYDNLYPS
RIIVGRPEGDKRLGEAARTFAALLQEGAMKKNIDTLFMGLTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLDTQAIIN
GVSLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYANVPENLIQAIVESNRTRKDFIADRVLNKAGYYDYYNRGDFNPNE
ERKCVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGAEVIIYEPTLEDGSTFFGSKVVNDLNTFKRQCQAIIANRYDACL
DDVNGKVYSRDVFRRD
>Mature_416_residues
MNTDIKIAVAGTGYVGMSIATLLAQHHQVIAVDVIPEKVEKINHQVSPIQDEYIEKYLAEKPLNLTATLNGATAYRDADF
VVIAAPTNYDPVKNYFDTSHVEEVIELVKSVNPNAIMVIKSTIPVGYTESVRKKLDTENVIFSPEFLRESKALYDNLYPS
RIIVGRPEGDKRLGEAARTFAALLQEGAMKKNIDTLFMGLTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLDTQAIIN
GVSLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYANVPENLIQAIVESNRTRKDFIADRVLNKAGYYDYYNRGDFNPNE
ERKCVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGAEVIIYEPTLEDGSTFFGSKVVNDLNTFKRQCQAIIANRYDACL
DDVNGKVYSRDVFRRD

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=388, Percent_Identity=28.3505154639175, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI296040438, Length=274, Percent_Identity=28.1021897810219, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI296040443, Length=235, Percent_Identity=27.6595744680851, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1788340, Length=412, Percent_Identity=59.4660194174757, Blast_Score=496, Evalue=1e-141,
Organism=Escherichia coli, GI48994968, Length=391, Percent_Identity=24.0409207161125, Blast_Score=82, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17560350, Length=404, Percent_Identity=26.980198019802, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI17136908, Length=389, Percent_Identity=26.4781491002571, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 46740; Mature: 46740

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTDIKIAVAGTGYVGMSIATLLAQHHQVIAVDVIPEKVEKINHQVSPIQDEYIEKYLAE
CCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCCCCHHHHHHHHHHC
KPLNLTATLNGATAYRDADFVVIAAPTNYDPVKNYFDTSHVEEVIELVKSVNPNAIMVIK
CCCCEEEEECCCEEECCCCEEEEECCCCCCHHHHHCCHHHHHHHHHHHHCCCCCEEEEEE
STIPVGYTESVRKKLDTENVIFSPEFLRESKALYDNLYPSRIIVGRPEGDKRLGEAARTF
CCCCCCCHHHHHHHCCCCCEEECHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHH
AALLQEGAMKKNIDTLFMGLTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLDTQAIIN
HHHHHHCCHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHC
GVSLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYANVPENLIQAIVESNRTRKDFIADR
CCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHH
VLNKAGYYDYYNRGDFNPNEERKCVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGAEVI
HHHHCCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEE
IYEPTLEDGSTFFGSKVVNDLNTFKRQCQAIIANRYDACLDDVNGKVYSRDVFRRD
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHCCC
>Mature Secondary Structure
MNTDIKIAVAGTGYVGMSIATLLAQHHQVIAVDVIPEKVEKINHQVSPIQDEYIEKYLAE
CCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCCCCHHHHHHHHHHC
KPLNLTATLNGATAYRDADFVVIAAPTNYDPVKNYFDTSHVEEVIELVKSVNPNAIMVIK
CCCCEEEEECCCEEECCCCEEEEECCCCCCHHHHHCCHHHHHHHHHHHHCCCCCEEEEEE
STIPVGYTESVRKKLDTENVIFSPEFLRESKALYDNLYPSRIIVGRPEGDKRLGEAARTF
CCCCCCCHHHHHHHCCCCCEEECHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHH
AALLQEGAMKKNIDTLFMGLTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLDTQAIIN
HHHHHHCCHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHC
GVSLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYANVPENLIQAIVESNRTRKDFIADR
CCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHH
VLNKAGYYDYYNRGDFNPNEERKCVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGAEVI
HHHHCCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEE
IYEPTLEDGSTFFGSKVVNDLNTFKRQCQAIIANRYDACLDDVNGKVYSRDVFRRD
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7682279; 11677609 [H]