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The map label for this gene is uxaC [H]

Identifier: 150009769

GI number: 150009769

Start: 3855629

End: 3857227

Strand: Reverse

Name: uxaC [H]

Synonym: BDI_3184

Alternate gene names: 150009769

Gene position: 3857227-3855629 (Counterclockwise)

Preceding gene: 150009770

Following gene: 150009768

Centisome position: 80.17

GC content: 48.66

Gene sequence:

>1599_bases
ATGGACCCTAATCATGGCTACCGGTGCCGTGGAGCCGACAGAGGAGAATCTATCCGCTTGGTTCAAGGCCGGCGTGACCT
GCGTAGGAATGGGATCCAAACTCTTCCCCAAAGAAGCGATAGCGGGAAACGATTGGCAATCCATTACCGATTTATGCCGC
AACGCCTTATCTATCATTCAAAAGTATCGCCAAGTATGAAAAACTTTTTAGATCAAGATTTCTTGCTCCAAACCGACACG
GCCCGTGAGTTATATCACGAGCATGCGGCGAAGATGCCCATCATTGATTACCATTGCCACCTAGATCCCCGGCAAATAGC
GGAGAATCATCAATTCGAGGATCTTACGGAGATATGGCTTGGCGGAGACCATTACAAATGGCGGGCGATGAGAGCAAATG
GTATCCCCGAGGAATACATCACCGGAGATAAGCCCTCTTACGAGAAATTCCTTAAATGGGCAGAGACGATGCCTTACACG
ATGCGAAACCCGCTTTATCATTGGACACATCTGGAACTTAGCCGTATATTTGGAATCCATAAAGTCTTGAATCCGGCTTC
CGCCGAGGAAATCTACGCAACTTGTACGGATAAACTGCGTACCCCCGAATATCGTGCGCAAGCCATCATGAAACGGATGA
ACGTAGAGGTTGTTTGTACGACCGACGATCCTATAGACTCATTGGAATTCCATCAAAAAATACGTTCAAGCGGATGCCAC
ATCCGTGTATATCCGGCATGGCGACCGGACAAGGTACTCGCTATCGATAATTTCAAGGCGCTAAATGACTATTTGTCCAA
GCTGGAGGCCGCCGCCGATAAGACCATCCTCACCTACAAGCATTTATTGGAGGCATTACAAAAGCGGCATGATTTCTTCG
CCGCTCAAGGGTGCCGGTTATCGGACCACGGGTTGGATACTTTCTATGCCGAACCTTATACCGAGCAGGAGATTGAGGTG
ATTTTCCTCAAGGCTCGTATGGGTAAATCGCTCACGGAGCAGGAAGTTCGCAAATACCGTTCGGCATTGCTATACGAATT
GGCGGCAATGGATGCCCGGAGTGGATGGGTACAGCAATTCCATATCGGCGCAAATCGGAATAATAACAAACGGATGTTCA
AGTTATTAGGGCCAGACACGGGTTTCGACGCTATCGATGATCAGCCGGTAGCTGTTTCCATGAACCGCTTTTTCAGCCAT
TTAGATCAAGAAGGGCTGTTAGCGAAAACGATCGTTTACAACCTGAATCCCCGCGACACCGAGTTGATGGTAGCCAATGC
CTACAATTTCAACGACGGCAGTGTACCCGGGAAGATGCAATATGGAGCGGCTTGGTGGTTCCTCGATCAGATCAAAGGCA
TGGAAGATCAGTTAAACGCACTTTCCAGCCTCGGTCTTTTAAGCCGTTTCGTCGGTATGCTGACAGATTCCCGCAGCTTC
CTGTCATATCCCCGCCATGAGTATTTCCGCCGGATCCTTTGTAATATGCTAGGCAATGAGATAGAGAAAGGCTTATTGCC
CGCCTCCGAGCTTTCCTTCATTGGACAGATGGTGGAGGACATCAGTTACAACAACGCTAAACGATACTTTGATTTCTGA

Upstream 100 bases:

>100_bases
TCGGCTTTGCCCAAGAAGTTGGTTGCGACCTTTGCAAGATATTCCCCGCCGGAAATGTAGGAGGTCCCTCATTTGTCAAG
AACATAAAGGCACCCATGCC

Downstream 100 bases:

>100_bases
TTATTGCAACCCGCATTGCAATGTTACTGCACGCCTGTCGCAGTAACACTGCACGTGCGTTGCAGTAAGGCTGCAACAGC
TTTGCAACATTTTATTCACA

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase [H]

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MDPNHGYRCRGADRGESIRLVQGRRDLRRNGIQTLPQRSDSGKRLAIHYRFMPQRLIYHSKVSPSMKNFLDQDFLLQTDT
ARELYHEHAAKMPIIDYHCHLDPRQIAENHQFEDLTEIWLGGDHYKWRAMRANGIPEEYITGDKPSYEKFLKWAETMPYT
MRNPLYHWTHLELSRIFGIHKVLNPASAEEIYATCTDKLRTPEYRAQAIMKRMNVEVVCTTDDPIDSLEFHQKIRSSGCH
IRVYPAWRPDKVLAIDNFKALNDYLSKLEAAADKTILTYKHLLEALQKRHDFFAAQGCRLSDHGLDTFYAEPYTEQEIEV
IFLKARMGKSLTEQEVRKYRSALLYELAAMDARSGWVQQFHIGANRNNNKRMFKLLGPDTGFDAIDDQPVAVSMNRFFSH
LDQEGLLAKTIVYNLNPRDTELMVANAYNFNDGSVPGKMQYGAAWWFLDQIKGMEDQLNALSSLGLLSRFVGMLTDSRSF
LSYPRHEYFRRILCNMLGNEIEKGLLPASELSFIGQMVEDISYNNAKRYFDF

Sequences:

>Translated_532_residues
MDPNHGYRCRGADRGESIRLVQGRRDLRRNGIQTLPQRSDSGKRLAIHYRFMPQRLIYHSKVSPSMKNFLDQDFLLQTDT
ARELYHEHAAKMPIIDYHCHLDPRQIAENHQFEDLTEIWLGGDHYKWRAMRANGIPEEYITGDKPSYEKFLKWAETMPYT
MRNPLYHWTHLELSRIFGIHKVLNPASAEEIYATCTDKLRTPEYRAQAIMKRMNVEVVCTTDDPIDSLEFHQKIRSSGCH
IRVYPAWRPDKVLAIDNFKALNDYLSKLEAAADKTILTYKHLLEALQKRHDFFAAQGCRLSDHGLDTFYAEPYTEQEIEV
IFLKARMGKSLTEQEVRKYRSALLYELAAMDARSGWVQQFHIGANRNNNKRMFKLLGPDTGFDAIDDQPVAVSMNRFFSH
LDQEGLLAKTIVYNLNPRDTELMVANAYNFNDGSVPGKMQYGAAWWFLDQIKGMEDQLNALSSLGLLSRFVGMLTDSRSF
LSYPRHEYFRRILCNMLGNEIEKGLLPASELSFIGQMVEDISYNNAKRYFDF
>Mature_532_residues
MDPNHGYRCRGADRGESIRLVQGRRDLRRNGIQTLPQRSDSGKRLAIHYRFMPQRLIYHSKVSPSMKNFLDQDFLLQTDT
ARELYHEHAAKMPIIDYHCHLDPRQIAENHQFEDLTEIWLGGDHYKWRAMRANGIPEEYITGDKPSYEKFLKWAETMPYT
MRNPLYHWTHLELSRIFGIHKVLNPASAEEIYATCTDKLRTPEYRAQAIMKRMNVEVVCTTDDPIDSLEFHQKIRSSGCH
IRVYPAWRPDKVLAIDNFKALNDYLSKLEAAADKTILTYKHLLEALQKRHDFFAAQGCRLSDHGLDTFYAEPYTEQEIEV
IFLKARMGKSLTEQEVRKYRSALLYELAAMDARSGWVQQFHIGANRNNNKRMFKLLGPDTGFDAIDDQPVAVSMNRFFSH
LDQEGLLAKTIVYNLNPRDTELMVANAYNFNDGSVPGKMQYGAAWWFLDQIKGMEDQLNALSSLGLLSRFVGMLTDSRSF
LSYPRHEYFRRILCNMLGNEIEKGLLPASELSFIGQMVEDISYNNAKRYFDF

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family [H]

Homologues:

Organism=Escherichia coli, GI2367192, Length=467, Percent_Identity=53.3190578158458, Blast_Score=514, Evalue=1e-147,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003766
- InterPro:   IPR023177 [H]

Pfam domain/function: PF02614 UxaC [H]

EC number: =5.3.1.12 [H]

Molecular weight: Translated: 61860; Mature: 61860

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00226 IF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPNHGYRCRGADRGESIRLVQGRRDLRRNGIQTLPQRSDSGKRLAIHYRFMPQRLIYHS
CCCCCCCEECCCCCCCCEEEECCHHHHHHCCHHHCCCCCCCCCEEEEEEEECHHHHHHHC
KVSPSMKNFLDQDFLLQTDTARELYHEHAAKMPIIDYHCHLDPRQIAENHQFEDLTEIWL
CCCHHHHHHCCCCCEEECHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCCHHHHHHHHC
GGDHYKWRAMRANGIPEEYITGDKPSYEKFLKWAETMPYTMRNPLYHWTHLELSRIFGIH
CCCCEEEEEEECCCCCHHHCCCCCCCHHHHHHHHHCCCHHHCCCCEEEHHHHHHHHHHHH
KVLNPASAEEIYATCTDKLRTPEYRAQAIMKRMNVEVVCTTDDPIDSLEFHQKIRSSGCH
HHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCCE
IRVYPAWRPDKVLAIDNFKALNDYLSKLEAAADKTILTYKHLLEALQKRHDFFAAQGCRL
EEEEECCCCCEEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCC
SDHGLDTFYAEPYTEQEIEVIFLKARMGKSLTEQEVRKYRSALLYELAAMDARSGWVQQF
CCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEE
HIGANRNNNKRMFKLLGPDTGFDAIDDQPVAVSMNRFFSHLDQEGLLAKTIVYNLNPRDT
EECCCCCCCCEEEEEECCCCCCCCCCCCCCEEEHHHHHHHCCCCCCEEEEEEEECCCCCC
ELMVANAYNFNDGSVPGKMQYGAAWWFLDQIKGMEDQLNALSSLGLLSRFVGMLTDSRSF
EEEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
LSYPRHEYFRRILCNMLGNEIEKGLLPASELSFIGQMVEDISYNNAKRYFDF
HCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHCCCC
>Mature Secondary Structure
MDPNHGYRCRGADRGESIRLVQGRRDLRRNGIQTLPQRSDSGKRLAIHYRFMPQRLIYHS
CCCCCCCEECCCCCCCCEEEECCHHHHHHCCHHHCCCCCCCCCEEEEEEEECHHHHHHHC
KVSPSMKNFLDQDFLLQTDTARELYHEHAAKMPIIDYHCHLDPRQIAENHQFEDLTEIWL
CCCHHHHHHCCCCCEEECHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCCHHHHHHHHC
GGDHYKWRAMRANGIPEEYITGDKPSYEKFLKWAETMPYTMRNPLYHWTHLELSRIFGIH
CCCCEEEEEEECCCCCHHHCCCCCCCHHHHHHHHHCCCHHHCCCCEEEHHHHHHHHHHHH
KVLNPASAEEIYATCTDKLRTPEYRAQAIMKRMNVEVVCTTDDPIDSLEFHQKIRSSGCH
HHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCCE
IRVYPAWRPDKVLAIDNFKALNDYLSKLEAAADKTILTYKHLLEALQKRHDFFAAQGCRL
EEEEECCCCCEEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCC
SDHGLDTFYAEPYTEQEIEVIFLKARMGKSLTEQEVRKYRSALLYELAAMDARSGWVQQF
CCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEE
HIGANRNNNKRMFKLLGPDTGFDAIDDQPVAVSMNRFFSHLDQEGLLAKTIVYNLNPRDT
EECCCCCCCCEEEEEECCCCCCCCCCCCCCEEEHHHHHHHCCCCCCEEEEEEEECCCCCC
ELMVANAYNFNDGSVPGKMQYGAAWWFLDQIKGMEDQLNALSSLGLLSRFVGMLTDSRSF
EEEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
LSYPRHEYFRRILCNMLGNEIEKGLLPASELSFIGQMVEDISYNNAKRYFDF
HCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]