Click here to switch to the map view.

The map label for this gene is thrS [H]

Identifier: 150009740

GI number: 150009740

Start: 3815079

End: 3816746

Strand: Direct

Name: thrS [H]

Synonym: BDI_3155

Alternate gene names: 150009740

Gene position: 3815079-3816746 (Clockwise)

Preceding gene: 150009734

Following gene: 150009741

Centisome position: 79.29

GC content: 46.64

Gene sequence:

>1668_bases
ATGTCTGAGACAATAACAATTTACTGCAAAAATAATAATACCTACAAGGATGTACCCATTGGTTCTTCGTTGTTGGACAT
TTATACGGCGCTTGGCGCTCCGCTTCGGTACAGGCCGATGAACGCGCAAGTGAATAATAAGACGGAAAGCTTGAACTTCC
GTTGCTGGCAACCGAAGGATATCGAATTTATCGACTATACTCAATTATCCGGATTGAGAACCTATGTCCGCTCGCTTTGC
CATATATTTTCCAAGGCGGTGTATGATATTTGGCCGACGGCGACCTTAAATCTGGAACATCCGGTGTCGAAAGGTTACTA
TTGCGTGATCCATAACGGCAAGAACATCGATCTGGAGACGATCGAGAGGATCAAGAAACGTATGTGGGAGTTGATTGACG
CGGATCTTCCTTTCCTCCATAAGAGTGTCCGTACGGTGGATGCCGCCGTATTGTTCAGGGAGCGGGGTATGAATGATAAG
GCTCGCTTAATAGAGACGGCGGGATTGCCTTATACCTCTTATTATGAGTTGGAAGGTTATATCAACTTCTTTTATGGCTG
TTTAACCCCTTCGACCGGCTATATCCAATTGTTTGACTTGGAACCGTATATGGATGGCGTTTTGCTCCGTATTCCGAAGC
AGACCGATCCGATGGAATTGCAGCCTGTCATCAAGCAGGATAAGATGTTCGAGGCTTATAAGGAACACCTTACATTGCAG
CGGACTGTCGGCTTAGATAATGTGGGGGATTTGAATTTAGCGATAGAGAAAGGCCGCTCTCAGGATATAATCCTTGTCTC
TGAGGCGATGCAGGAAAAACAGGTTGCTAAGATCGCCGAAAAGATCGCCGATGGATATAAAGAGGGCATCCGTATCGTCT
TGATCTCTGGCCCTTCTTCTTCGGGAAAGACTACGTTTTGCAAGCGTTTGCAAGTGCAATTAACAACTAACCTGCTTCAT
CCGGTAGGAATTTCCTTGGATGATTATTTCTTGAACCGGGAAGATACACCGAAGGATGAGCATGGCGAGTATGATTTTGA
ATCCTTGTATGCGCTGGATTTACCCTATTTTAATAAGGATTTGAAGAAGTTGTTATCCGGGGAAGAGATCGATTTGCCGA
CTTTTAATTTCGAGACCGGCCAACGGGTTTTCAAAGGGAAGAAGCTTAAGCTTCGTGAGAACTCGATCTTGGTGATAGAA
GGTATCCATGCCTTGAATCCGGAGCTGACGGAGTTTATCGATGATAAATATAAATATCGGGTATATGTCTCGGTCTTGAC
CTCTATCTCTTTGGATAACCATAATTGGATACCGACGACGGATAATCGTCTGCTGCGCCGTATCATCCGGGATTATCGCT
TTAGGGGATATTCGGCGGAAGATACGATCAACCGTTGGCCGAGCGTTCGCCGGGGTGAGGATAAATGGATCTTTCCGTAT
CAGGAGAATGCGGACGCTATGTTTAACAGCGCCATGTTGTATGAGCTGGCCGCCTTGCGCAAATTTGCGGAACCGATCCT
CGCGCAAGTGCCGGAGAGTAGTAAGGCGAATGCGGAGGCGTATCGTTTGCTCCGTTTCCTCCGCTACTTTAATTACATCC
CGACGGAGGAACTTCCCGGAACTTCCTTGCTCCGTGAATTCTTGGGGGGAGGAAGCTTCAAGTACTAG

Upstream 100 bases:

>100_bases
AAAAAAGAATAGTCCATTTAAATTACGTTTAAGTGGATTGTATATCCGATTAATATTCCTAACTTTAGGGGGCGAATTTA
CAAATAATAACTGAGATAGT

Downstream 100 bases:

>100_bases
GTAGAATCATACTCTATAAAGCCTTTAAAAAAAGACGTACGTGTTTTTCCGAAAACATGTACGTCTTTTTTTGAAAACAT
GTACGTGTTTTTTTCATATC

Product: uridine kinase

Products: NA

Alternate protein names: Threonine--tRNA ligase; ThrRS [H]

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MSETITIYCKNNNTYKDVPIGSSLLDIYTALGAPLRYRPMNAQVNNKTESLNFRCWQPKDIEFIDYTQLSGLRTYVRSLC
HIFSKAVYDIWPTATLNLEHPVSKGYYCVIHNGKNIDLETIERIKKRMWELIDADLPFLHKSVRTVDAAVLFRERGMNDK
ARLIETAGLPYTSYYELEGYINFFYGCLTPSTGYIQLFDLEPYMDGVLLRIPKQTDPMELQPVIKQDKMFEAYKEHLTLQ
RTVGLDNVGDLNLAIEKGRSQDIILVSEAMQEKQVAKIAEKIADGYKEGIRIVLISGPSSSGKTTFCKRLQVQLTTNLLH
PVGISLDDYFLNREDTPKDEHGEYDFESLYALDLPYFNKDLKKLLSGEEIDLPTFNFETGQRVFKGKKLKLRENSILVIE
GIHALNPELTEFIDDKYKYRVYVSVLTSISLDNHNWIPTTDNRLLRRIIRDYRFRGYSAEDTINRWPSVRRGEDKWIFPY
QENADAMFNSAMLYELAALRKFAEPILAQVPESSKANAEAYRLLRFLRYFNYIPTEELPGTSLLREFLGGGSFKY

Sequences:

>Translated_555_residues
MSETITIYCKNNNTYKDVPIGSSLLDIYTALGAPLRYRPMNAQVNNKTESLNFRCWQPKDIEFIDYTQLSGLRTYVRSLC
HIFSKAVYDIWPTATLNLEHPVSKGYYCVIHNGKNIDLETIERIKKRMWELIDADLPFLHKSVRTVDAAVLFRERGMNDK
ARLIETAGLPYTSYYELEGYINFFYGCLTPSTGYIQLFDLEPYMDGVLLRIPKQTDPMELQPVIKQDKMFEAYKEHLTLQ
RTVGLDNVGDLNLAIEKGRSQDIILVSEAMQEKQVAKIAEKIADGYKEGIRIVLISGPSSSGKTTFCKRLQVQLTTNLLH
PVGISLDDYFLNREDTPKDEHGEYDFESLYALDLPYFNKDLKKLLSGEEIDLPTFNFETGQRVFKGKKLKLRENSILVIE
GIHALNPELTEFIDDKYKYRVYVSVLTSISLDNHNWIPTTDNRLLRRIIRDYRFRGYSAEDTINRWPSVRRGEDKWIFPY
QENADAMFNSAMLYELAALRKFAEPILAQVPESSKANAEAYRLLRFLRYFNYIPTEELPGTSLLREFLGGGSFKY
>Mature_554_residues
SETITIYCKNNNTYKDVPIGSSLLDIYTALGAPLRYRPMNAQVNNKTESLNFRCWQPKDIEFIDYTQLSGLRTYVRSLCH
IFSKAVYDIWPTATLNLEHPVSKGYYCVIHNGKNIDLETIERIKKRMWELIDADLPFLHKSVRTVDAAVLFRERGMNDKA
RLIETAGLPYTSYYELEGYINFFYGCLTPSTGYIQLFDLEPYMDGVLLRIPKQTDPMELQPVIKQDKMFEAYKEHLTLQR
TVGLDNVGDLNLAIEKGRSQDIILVSEAMQEKQVAKIAEKIADGYKEGIRIVLISGPSSSGKTTFCKRLQVQLTTNLLHP
VGISLDDYFLNREDTPKDEHGEYDFESLYALDLPYFNKDLKKLLSGEEIDLPTFNFETGQRVFKGKKLKLRENSILVIEG
IHALNPELTEFIDDKYKYRVYVSVLTSISLDNHNWIPTTDNRLLRRIIRDYRFRGYSAEDTINRWPSVRRGEDKWIFPYQ
ENADAMFNSAMLYELAALRKFAEPILAQVPESSKANAEAYRLLRFLRYFNYIPTEELPGTSLLREFLGGGSFKY

Specific function: Thrs Is Also A Translational Repressor Protein, It Controls The Translation Of Its Own Gene By Binding To Its mRNA. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: 700 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR012675
- InterPro:   IPR004095
- InterPro:   IPR012676
- InterPro:   IPR002320
- InterPro:   IPR018163
- InterPro:   IPR012947 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF02824 TGS; PF00587 tRNA-synt_2b; PF07973 tRNA_SAD [H]

EC number: =6.1.1.3 [H]

Molecular weight: Translated: 64221; Mature: 64090

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETITIYCKNNNTYKDVPIGSSLLDIYTALGAPLRYRPMNAQVNNKTESLNFRCWQPKD
CCCEEEEEECCCCEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEECCCCC
IEFIDYTQLSGLRTYVRSLCHIFSKAVYDIWPTATLNLEHPVSKGYYCVIHNGKNIDLET
CCEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCHHH
IERIKKRMWELIDADLPFLHKSVRTVDAAVLFRERGMNDKARLIETAGLPYTSYYELEGY
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEHHHH
INFFYGCLTPSTGYIQLFDLEPYMDGVLLRIPKQTDPMELQPVIKQDKMFEAYKEHLTLQ
HHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHEEH
RTVGLDNVGDLNLAIEKGRSQDIILVSEAMQEKQVAKIAEKIADGYKEGIRIVLISGPSS
HHCCCCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCC
SGKTTFCKRLQVQLTTNLLHPVGISLDDYFLNREDTPKDEHGEYDFESLYALDLPYFNKD
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCHHHEEEECCCCCCHH
LKKLLSGEEIDLPTFNFETGQRVFKGKKLKLRENSILVIEGIHALNPELTEFIDDKYKYR
HHHHHCCCCCCCCCCCCCCCHHHHCCCCEEEECCCEEEEECCHHCCHHHHHHHCCCHHEE
VYVSVLTSISLDNHNWIPTTDNRLLRRIIRDYRFRGYSAEDTINRWPSVRRGEDKWIFPY
EEEEEEHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCEEECC
QENADAMFNSAMLYELAALRKFAEPILAQVPESSKANAEAYRLLRFLRYFNYIPTEELPG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
TSLLREFLGGGSFKY
HHHHHHHHCCCCCCC
>Mature Secondary Structure 
SETITIYCKNNNTYKDVPIGSSLLDIYTALGAPLRYRPMNAQVNNKTESLNFRCWQPKD
CCEEEEEECCCCEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEECCCCC
IEFIDYTQLSGLRTYVRSLCHIFSKAVYDIWPTATLNLEHPVSKGYYCVIHNGKNIDLET
CCEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCHHH
IERIKKRMWELIDADLPFLHKSVRTVDAAVLFRERGMNDKARLIETAGLPYTSYYELEGY
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEHHHH
INFFYGCLTPSTGYIQLFDLEPYMDGVLLRIPKQTDPMELQPVIKQDKMFEAYKEHLTLQ
HHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHEEH
RTVGLDNVGDLNLAIEKGRSQDIILVSEAMQEKQVAKIAEKIADGYKEGIRIVLISGPSS
HHCCCCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCC
SGKTTFCKRLQVQLTTNLLHPVGISLDDYFLNREDTPKDEHGEYDFESLYALDLPYFNKD
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCHHHEEEECCCCCCHH
LKKLLSGEEIDLPTFNFETGQRVFKGKKLKLRENSILVIEGIHALNPELTEFIDDKYKYR
HHHHHCCCCCCCCCCCCCCCHHHHCCCCEEEECCCEEEEECCHHCCHHHHHHHCCCHHEE
VYVSVLTSISLDNHNWIPTTDNRLLRRIIRDYRFRGYSAEDTINRWPSVRRGEDKWIFPY
EEEEEEHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCEEECC
QENADAMFNSAMLYELAALRKFAEPILAQVPESSKANAEAYRLLRFLRYFNYIPTEELPG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
TSLLREFLGGGSFKY
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA