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The map label for this gene is nagA [H]

Identifier: 150009737

GI number: 150009737

Start: 3810664

End: 3811839

Strand: Reverse

Name: nagA [H]

Synonym: BDI_3152

Alternate gene names: 150009737

Gene position: 3811839-3810664 (Counterclockwise)

Preceding gene: 150009738

Following gene: 150009736

Centisome position: 79.23

GC content: 47.96

Gene sequence:

>1176_bases
ATGGAAAGCGCATTTCTTAAAATCATAAACGCAAAAGTATTAACTCCTTCGGGTCTCCTACCAAACGGGCAAATCATCAT
CTCGGATGGGAAAATAGTGGAGATCACCGGGCAAAACCGGGAGATTCCTCATGCGGAGATCATCGACGCAAAAGGATATT
ATGTGGCTCCCGGCTGTATCGACACGCATGTACACGGCGGCAACGGACATGATTTCACGGAAGCTACCCCGAAAGCGTTC
TATGCGATCACAAGAGCACATGCTTTACAGGGAACAACGGCTTTATATCCTACATTGGCAGCTGCCCCTATCGATACCTT
CCGGGAAGCGATCAAGACCTGCGAGCACATCATGAACCACCCGGAACAGGGAGCCCGCATCATGGGATTACATCTCGAAG
GCAACTATTTGAATATGGCTATGAAAGGCGGACAAGACCCTAATTATATTTACCCGCCCGATCCCCAAGAATATAAGGAA
TTACTAAACAGTACCCAATGTGTTAAACGCTGGAGCGCCGCCCCCGAGCTTGACGGGGCTTTGGAATTCGGTAAATATGC
GTCAGCTCATGGTGTGTTGGTTTCACTAGCCCACACCACAGCCGATTATCTCCAAGTGAAAAAAGCATACGAAGCCGGAT
TCACCCATGCTACCCACTTCTACAATGCCATGACTTCCGTCCATAAAGACCGTGAGTATAAACATGAAGGAACGGTAGAA
GGTATTTATCTCATGAAAGATATGACCGTTGAAGTTGTAGCCGATGGTATCCACGTACCGCCGGCAATCTTAAAGTTGGT
ATATCAAATCAAAGGGGTAGAACGTACGTCCTTAATCACGGACGCAATGGCCGCCGCCGCTTGCGATAACGGTACGGAAC
ATTTTCCGGACTCCCGGGTAATTATCGAGGAAGGCGTATGTAAATTAGCCGATCGCTCAGCTATCGCGGGAAGTATAGCT
ACCGGAATCCGTTTGATCCGTACCCTAGTCGAGAAAGCGGAAATTCCATTGCACGACGCTGTTCGTATGGCTTCCGAAAG
CCCAGCCCGCCTAATGGGTCTTTTAGACCGTAAAGGAACATTGGAGAAAGGAAAGGATGCCGATATCATCATTTTCAACA
ACGATATAGAGATTCAAGAGACCTTCATCGAAGGTAAACGGCTCTCCAAAGAATAA

Upstream 100 bases:

>100_bases
GATCCGCTACCCCGAGGGGCAACCGGGAAATCCAATATAATCCCCCGTTGTCCTATAAGGATAACTTATTACTGATTCCA
AAAGACTAAAAACAAGATAT

Downstream 100 bases:

>100_bases
GAAATCCAATAAACAATGACTTCTCCTATCTTGTTTTTAGATAAATAAGGGCATGAATGTATATGGAAAACGTAAAAGAA
CATTACTGGAGATACTCATT

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MESAFLKIINAKVLTPSGLLPNGQIIISDGKIVEITGQNREIPHAEIIDAKGYYVAPGCIDTHVHGGNGHDFTEATPKAF
YAITRAHALQGTTALYPTLAAAPIDTFREAIKTCEHIMNHPEQGARIMGLHLEGNYLNMAMKGGQDPNYIYPPDPQEYKE
LLNSTQCVKRWSAAPELDGALEFGKYASAHGVLVSLAHTTADYLQVKKAYEAGFTHATHFYNAMTSVHKDREYKHEGTVE
GIYLMKDMTVEVVADGIHVPPAILKLVYQIKGVERTSLITDAMAAAACDNGTEHFPDSRVIIEEGVCKLADRSAIAGSIA
TGIRLIRTLVEKAEIPLHDAVRMASESPARLMGLLDRKGTLEKGKDADIIIFNNDIEIQETFIEGKRLSKE

Sequences:

>Translated_391_residues
MESAFLKIINAKVLTPSGLLPNGQIIISDGKIVEITGQNREIPHAEIIDAKGYYVAPGCIDTHVHGGNGHDFTEATPKAF
YAITRAHALQGTTALYPTLAAAPIDTFREAIKTCEHIMNHPEQGARIMGLHLEGNYLNMAMKGGQDPNYIYPPDPQEYKE
LLNSTQCVKRWSAAPELDGALEFGKYASAHGVLVSLAHTTADYLQVKKAYEAGFTHATHFYNAMTSVHKDREYKHEGTVE
GIYLMKDMTVEVVADGIHVPPAILKLVYQIKGVERTSLITDAMAAAACDNGTEHFPDSRVIIEEGVCKLADRSAIAGSIA
TGIRLIRTLVEKAEIPLHDAVRMASESPARLMGLLDRKGTLEKGKDADIIIFNNDIEIQETFIEGKRLSKE
>Mature_391_residues
MESAFLKIINAKVLTPSGLLPNGQIIISDGKIVEITGQNREIPHAEIIDAKGYYVAPGCIDTHVHGGNGHDFTEATPKAF
YAITRAHALQGTTALYPTLAAAPIDTFREAIKTCEHIMNHPEQGARIMGLHLEGNYLNMAMKGGQDPNYIYPPDPQEYKE
LLNSTQCVKRWSAAPELDGALEFGKYASAHGVLVSLAHTTADYLQVKKAYEAGFTHATHFYNAMTSVHKDREYKHEGTVE
GIYLMKDMTVEVVADGIHVPPAILKLVYQIKGVERTSLITDAMAAAACDNGTEHFPDSRVIIEEGVCKLADRSAIAGSIA
TGIRLIRTLVEKAEIPLHDAVRMASESPARLMGLLDRKGTLEKGKDADIIIFNNDIEIQETFIEGKRLSKE

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=421, Percent_Identity=26.1282660332542, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI224922791, Length=424, Percent_Identity=26.1792452830189, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI1786892, Length=386, Percent_Identity=29.2746113989637, Blast_Score=169, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17553768, Length=398, Percent_Identity=28.391959798995, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI19920392, Length=391, Percent_Identity=27.1099744245524, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281361140, Length=408, Percent_Identity=25.4901960784314, Blast_Score=133, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 42805; Mature: 42805

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESAFLKIINAKVLTPSGLLPNGQIIISDGKIVEITGQNREIPHAEIIDAKGYYVAPGCI
CCCHHEEEHHCEEECCCCCCCCCEEEEECCEEEEEECCCCCCCCCEEEECCCCEECCCCE
DTHVHGGNGHDFTEATPKAFYAITRAHALQGTTALYPTLAAAPIDTFREAIKTCEHIMNH
ECCEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCC
PEQGARIMGLHLEGNYLNMAMKGGQDPNYIYPPDPQEYKELLNSTQCVKRWSAAPELDGA
CCCCCEEEEEEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCH
LEFGKYASAHGVLVSLAHTTADYLQVKKAYEAGFTHATHFYNAMTSVHKDREYKHEGTVE
HHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
GIYLMKDMTVEVVADGIHVPPAILKLVYQIKGVERTSLITDAMAAAACDNGTEHFPDSRV
EEEEEECCEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCEE
IIEEGVCKLADRSAIAGSIATGIRLIRTLVEKAEIPLHDAVRMASESPARLMGLLDRKGT
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCC
LEKGKDADIIIFNNDIEIQETFIEGKRLSKE
CCCCCCCEEEEECCCCEEHHHHHCCHHCCCC
>Mature Secondary Structure
MESAFLKIINAKVLTPSGLLPNGQIIISDGKIVEITGQNREIPHAEIIDAKGYYVAPGCI
CCCHHEEEHHCEEECCCCCCCCCEEEEECCEEEEEECCCCCCCCCEEEECCCCEECCCCE
DTHVHGGNGHDFTEATPKAFYAITRAHALQGTTALYPTLAAAPIDTFREAIKTCEHIMNH
ECCEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCC
PEQGARIMGLHLEGNYLNMAMKGGQDPNYIYPPDPQEYKELLNSTQCVKRWSAAPELDGA
CCCCCEEEEEEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCH
LEFGKYASAHGVLVSLAHTTADYLQVKKAYEAGFTHATHFYNAMTSVHKDREYKHEGTVE
HHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
GIYLMKDMTVEVVADGIHVPPAILKLVYQIKGVERTSLITDAMAAAACDNGTEHFPDSRV
EEEEEECCEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCEE
IIEEGVCKLADRSAIAGSIATGIRLIRTLVEKAEIPLHDAVRMASESPARLMGLLDRKGT
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCC
LEKGKDADIIIFNNDIEIQETFIEGKRLSKE
CCCCCCCEEEEECCCCEEHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]