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The map label for this gene is zraR [H]

Identifier: 150009427

GI number: 150009427

Start: 3382323

End: 3383690

Strand: Reverse

Name: zraR [H]

Synonym: BDI_2835

Alternate gene names: 150009427

Gene position: 3383690-3382323 (Counterclockwise)

Preceding gene: 150009431

Following gene: 150009426

Centisome position: 70.33

GC content: 51.24

Gene sequence:

>1368_bases
ATGGAAGAAAAAGGAAAGATATTGATCATCGACGATAATAAGGATGTGTTGTTCGCATTGAACTTACTGTTGGAGCCGTA
CATGCAAAAGGTGAAGGTAACGACACAACCGGCACGCATCGAGTATTTCATGCGGACGTTCCAACCGGACGTGGTCTTGC
TGGATATGAATTTCCATCGGGATGCCGTGAGCGGGCAGGAGGGTTTTGAGTATTTGGGACAAATCTTGGAGATCGATCCG
CAGGCGGTCGTGATCTTCATGACGGCCTATTCGGATATAGAGAAAGCGGTCAAGGCCATTAAGGTTGGCGCTACCGATTT
CATCTCCAAGCCGTGGGAAACGGAGAAGTTGCTGGCTACCCTCTCGTCGGGCATTCGATTGAGCCATTCCCGTAAGGAGG
TAGGACGTTTGCGAGAGCAAATGAAAGCCATGAAGGAGGACGACACATTGCCGGAATTGATCGGTGAGTCGCCGGCTATG
CTGAAGGTAAAAGACACGATCTACAAACTTGTGGAGACCGACGCGAATATATTGATTACCGGTGAGAGCGGTACCGGAAA
AGATCTGGTTGCCCGTTTGTTGAGGCATTACTCGCCCCGGCGTGACGATGCTTTCGTGACGATCGACTTGGGAAGTATCC
CGGAACAATTATTTGAGAGTGAGTTGTTCGGCTATGAGAAAGGTGCCTTCACGGATGCCCGAAGATCCAAGCCGGGACGT
ATGGAGATGGCTTCCGGCGGTACGCTCTTTCTGGACGAGATCGGTAACCTGTCCTTGCCGATGCAATCTAAATTGCTGAC
AGCTATAGAGAAACGTCATATCACCCGTTTGGGAGCGGTGGAACCGATCTCGATCGATGTTCGTTTGATCTGCGCCACCA
ACGCCAATCTGCGTCAGCTGGTGGGCGAGGGGAGTTTCCGGCAAGACTTGCTCTATCGGATCAATACCATAGAGATAGCC
ATACCACCGCTGCGTGAGCGGGGAGAGGATATCTTGATGCTGGCCGATCATTTCCAGAGGCTGTATAGCCGGAAATACAA
GAAAACGATCAAAGGGTTGAGCCGGGAGGCGGGGAGTAAGCTGATGAAATACCCTTGGCCCGGTAATGTCCGGGAGTTGC
AGCATGTTTTGGAGCGAGCCGTGATCTTGAACGAGGGTACGGTGCTGAGACCGGATGATTTCCCTCTCTATACAGCCTCT
TACGAGCGGAAGAAGGAGCTGGACCCTGATTTGAATCTAGAGCAAGCCGAGCGGAAAATCATCGAGCGAGCCTTGCGGCA
AAGCAATGGTAATATGAGCTATGCCGCCGAGCTATTGGGTATCACCCGTTTTTCCTTGTATCGTAAAATAGAGAAGTTCG
GCTTATGA

Upstream 100 bases:

>100_bases
TCATAGAAAAATCTGTATTTCTTCATGTAGTGCGATAGCGTACATTTTTTGTGCGATAATGCACGTACAAGCTGTCTTTA
TTCCCTTTATCTTTGTCCGT

Downstream 100 bases:

>100_bases
GATCGTATGCGTTCACGGTCATCTCGCACATCCTAGGCATCGTCTTGTCTACGGGACTCCTGTTCTATTGCGTGCATGAG
GAGATTATCTTTTGTCCTAC

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MEEKGKILIIDDNKDVLFALNLLLEPYMQKVKVTTQPARIEYFMRTFQPDVVLLDMNFHRDAVSGQEGFEYLGQILEIDP
QAVVIFMTAYSDIEKAVKAIKVGATDFISKPWETEKLLATLSSGIRLSHSRKEVGRLREQMKAMKEDDTLPELIGESPAM
LKVKDTIYKLVETDANILITGESGTGKDLVARLLRHYSPRRDDAFVTIDLGSIPEQLFESELFGYEKGAFTDARRSKPGR
MEMASGGTLFLDEIGNLSLPMQSKLLTAIEKRHITRLGAVEPISIDVRLICATNANLRQLVGEGSFRQDLLYRINTIEIA
IPPLRERGEDILMLADHFQRLYSRKYKKTIKGLSREAGSKLMKYPWPGNVRELQHVLERAVILNEGTVLRPDDFPLYTAS
YERKKELDPDLNLEQAERKIIERALRQSNGNMSYAAELLGITRFSLYRKIEKFGL

Sequences:

>Translated_455_residues
MEEKGKILIIDDNKDVLFALNLLLEPYMQKVKVTTQPARIEYFMRTFQPDVVLLDMNFHRDAVSGQEGFEYLGQILEIDP
QAVVIFMTAYSDIEKAVKAIKVGATDFISKPWETEKLLATLSSGIRLSHSRKEVGRLREQMKAMKEDDTLPELIGESPAM
LKVKDTIYKLVETDANILITGESGTGKDLVARLLRHYSPRRDDAFVTIDLGSIPEQLFESELFGYEKGAFTDARRSKPGR
MEMASGGTLFLDEIGNLSLPMQSKLLTAIEKRHITRLGAVEPISIDVRLICATNANLRQLVGEGSFRQDLLYRINTIEIA
IPPLRERGEDILMLADHFQRLYSRKYKKTIKGLSREAGSKLMKYPWPGNVRELQHVLERAVILNEGTVLRPDDFPLYTAS
YERKKELDPDLNLEQAERKIIERALRQSNGNMSYAAELLGITRFSLYRKIEKFGL
>Mature_455_residues
MEEKGKILIIDDNKDVLFALNLLLEPYMQKVKVTTQPARIEYFMRTFQPDVVLLDMNFHRDAVSGQEGFEYLGQILEIDP
QAVVIFMTAYSDIEKAVKAIKVGATDFISKPWETEKLLATLSSGIRLSHSRKEVGRLREQMKAMKEDDTLPELIGESPAM
LKVKDTIYKLVETDANILITGESGTGKDLVARLLRHYSPRRDDAFVTIDLGSIPEQLFESELFGYEKGAFTDARRSKPGR
MEMASGGTLFLDEIGNLSLPMQSKLLTAIEKRHITRLGAVEPISIDVRLICATNANLRQLVGEGSFRQDLLYRINTIEIA
IPPLRERGEDILMLADHFQRLYSRKYKKTIKGLSREAGSKLMKYPWPGNVRELQHVLERAVILNEGTVLRPDDFPLYTAS
YERKKELDPDLNLEQAERKIIERALRQSNGNMSYAAELLGITRFSLYRKIEKFGL

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=450, Percent_Identity=38.4444444444444, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI1788550, Length=466, Percent_Identity=35.4077253218884, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI1790299, Length=479, Percent_Identity=35.2818371607516, Blast_Score=285, Evalue=6e-78,
Organism=Escherichia coli, GI1789233, Length=324, Percent_Identity=42.5925925925926, Blast_Score=244, Evalue=9e-66,
Organism=Escherichia coli, GI1788905, Length=391, Percent_Identity=33.7595907928389, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI87082117, Length=326, Percent_Identity=41.1042944785276, Blast_Score=241, Evalue=8e-65,
Organism=Escherichia coli, GI1786524, Length=331, Percent_Identity=38.6706948640483, Blast_Score=221, Evalue=9e-59,
Organism=Escherichia coli, GI1789087, Length=347, Percent_Identity=37.463976945245, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI87082152, Length=324, Percent_Identity=39.5061728395062, Blast_Score=218, Evalue=6e-58,
Organism=Escherichia coli, GI87081872, Length=310, Percent_Identity=39.6774193548387, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1787583, Length=342, Percent_Identity=33.9181286549708, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI87081858, Length=284, Percent_Identity=31.3380281690141, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI1789828, Length=233, Percent_Identity=35.6223175965665, Blast_Score=125, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51806; Mature: 51806

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEKGKILIIDDNKDVLFALNLLLEPYMQKVKVTTQPARIEYFMRTFQPDVVLLDMNFHR
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCC
DAVSGQEGFEYLGQILEIDPQAVVIFMTAYSDIEKAVKAIKVGATDFISKPWETEKLLAT
CCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHH
LSSGIRLSHSRKEVGRLREQMKAMKEDDTLPELIGESPAMLKVKDTIYKLVETDANILIT
HHHCCEECCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEHHHHHHHHHHCCCCEEEE
GESGTGKDLVARLLRHYSPRRDDAFVTIDLGSIPEQLFESELFGYEKGAFTDARRSKPGR
CCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHCCCCCC
MEMASGGTLFLDEIGNLSLPMQSKLLTAIEKRHITRLGAVEPISIDVRLICATNANLRQL
EEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCHHHHH
VGEGSFRQDLLYRINTIEIAIPPLRERGEDILMLADHFQRLYSRKYKKTIKGLSREAGSK
HCCCCHHHHHHHHEEEEEEEECCHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LMKYPWPGNVRELQHVLERAVILNEGTVLRPDDFPLYTASYERKKELDPDLNLEQAERKI
CCCCCCCCCHHHHHHHHHHHHEECCCCEECCCCCCEEECCCHHHHCCCCCCCHHHHHHHH
IERALRQSNGNMSYAAELLGITRFSLYRKIEKFGL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEEKGKILIIDDNKDVLFALNLLLEPYMQKVKVTTQPARIEYFMRTFQPDVVLLDMNFHR
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCC
DAVSGQEGFEYLGQILEIDPQAVVIFMTAYSDIEKAVKAIKVGATDFISKPWETEKLLAT
CCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHH
LSSGIRLSHSRKEVGRLREQMKAMKEDDTLPELIGESPAMLKVKDTIYKLVETDANILIT
HHHCCEECCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEHHHHHHHHHHCCCCEEEE
GESGTGKDLVARLLRHYSPRRDDAFVTIDLGSIPEQLFESELFGYEKGAFTDARRSKPGR
CCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHCCCCCC
MEMASGGTLFLDEIGNLSLPMQSKLLTAIEKRHITRLGAVEPISIDVRLICATNANLRQL
EEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCHHHHH
VGEGSFRQDLLYRINTIEIAIPPLRERGEDILMLADHFQRLYSRKYKKTIKGLSREAGSK
HCCCCHHHHHHHHEEEEEEEECCHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LMKYPWPGNVRELQHVLERAVILNEGTVLRPDDFPLYTASYERKKELDPDLNLEQAERKI
CCCCCCCCCHHHHHHHHHHHHEECCCCEECCCCCCEEECCCHHHHCCCCCCCHHHHHHHH
IERALRQSNGNMSYAAELLGITRFSLYRKIEKFGL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]