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The map label for this gene is lytS [H]

Identifier: 150009153

GI number: 150009153

Start: 3026902

End: 3027918

Strand: Reverse

Name: lytS [H]

Synonym: BDI_2555

Alternate gene names: 150009153

Gene position: 3027918-3026902 (Counterclockwise)

Preceding gene: 150009154

Following gene: 150009152

Centisome position: 62.93

GC content: 41.49

Gene sequence:

>1017_bases
ATGGGTTCATTGGATGAAAAGATATCAGTGGTCAAGGCTAAACCTTGGTTGGTCAGTTTGGTTTGCGCGGTGTTTATCGC
CTACCCGAATTTGGCATGGATCTTTTGTGACATGAGCTATCTGGCTCCGAACGATCATCAAGGATTTTTACTCTTCTTTG
GGTTCCGTTTTCTTTACTTCTGGGGACTTATTTGGTTTTTGCTGAAAAGTAACTTGAGGCATGAGGATTGTACCTCCTTC
TTCGAGCGGTTGCTCTGGAATGCCCTGTACGTTTCCGGAGGCTTTGTTGTCTATAAATTGATCTCCTTCCTGACTATTAG
TTATGATCGTTTTTTGAGTATCATTATCTTCCAGTTTATCGTGTTGGCGTTGTTATGTACCTTGATCGGCTATATACAAA
TGCTATATCACAATCAACGGGAAAAGGATCAATTGATCGAGAATCTGCGTGTCGAGAATTTGCAGAGCCGCTGCGATGCA
TTGGTGAACCAGATCAATCCGCATTTCTTTTTCAATTCATTGAATGGAATCTCCTCCTTGATACGGAAGAAAAACGATGA
GAATACCTTGTTGTATGTTACGAAATTGTCCGATATATTCCGTTATATCCTTCAGAGTGATAAAAAGAATTTGGTACCAC
TGTCGGAGGAGCTTGCGTTTATAGAGGCTTTTCAGCATGTAATGGTAGTCCGTTTCGCCAATAAGCTTACTTTTACGATC
GAAGTTCCCGAAGATAAGCGGAACTTGCGAATTCCCGTATTATCTTTGCTTCCGTTGGTAGAGAACGTGACGGTACATAA
TATTATAGACAGCGAGCACCGGATGGATATCTTGATCCGGCTGAACGAGCGAATGGAACTGGTTGTTTCTAATCCAATCT
ATCCGAAATTGACCTTACCGGATACGAATGGAACCGGGCTTAAGAATCTGGAGAATCGTTTCTTGCTATTAATGAATAAA
CAAATACGGGTAGAATCTGATGAGGATGAGTTTCAGGTATACCTACCCCTAAAATGA

Upstream 100 bases:

>100_bases
GATAATTCGTCTTTAACTCTTTTTTTTCGCTTTCTTCCTGCACTGGAGAAGGATGTGAATGATTTTTTATTCCTTTGTAT
ACGAAAAAAGATACAATCGT

Downstream 100 bases:

>100_bases
TGCTATATGAGAATACTGATCGTAGAGGACGAGACCGCCGCCTATGAGAACTTAGCGGATATGTTGGTTACAATAGATCC
CACGCTTGAGATCATGGGAA

Product: putative two-component system sensor histidine kinase

Products: NA

Alternate protein names: Autolysin sensor kinase [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MGSLDEKISVVKAKPWLVSLVCAVFIAYPNLAWIFCDMSYLAPNDHQGFLLFFGFRFLYFWGLIWFLLKSNLRHEDCTSF
FERLLWNALYVSGGFVVYKLISFLTISYDRFLSIIIFQFIVLALLCTLIGYIQMLYHNQREKDQLIENLRVENLQSRCDA
LVNQINPHFFFNSLNGISSLIRKKNDENTLLYVTKLSDIFRYILQSDKKNLVPLSEELAFIEAFQHVMVVRFANKLTFTI
EVPEDKRNLRIPVLSLLPLVENVTVHNIIDSEHRMDILIRLNERMELVVSNPIYPKLTLPDTNGTGLKNLENRFLLLMNK
QIRVESDEDEFQVYLPLK

Sequences:

>Translated_338_residues
MGSLDEKISVVKAKPWLVSLVCAVFIAYPNLAWIFCDMSYLAPNDHQGFLLFFGFRFLYFWGLIWFLLKSNLRHEDCTSF
FERLLWNALYVSGGFVVYKLISFLTISYDRFLSIIIFQFIVLALLCTLIGYIQMLYHNQREKDQLIENLRVENLQSRCDA
LVNQINPHFFFNSLNGISSLIRKKNDENTLLYVTKLSDIFRYILQSDKKNLVPLSEELAFIEAFQHVMVVRFANKLTFTI
EVPEDKRNLRIPVLSLLPLVENVTVHNIIDSEHRMDILIRLNERMELVVSNPIYPKLTLPDTNGTGLKNLENRFLLLMNK
QIRVESDEDEFQVYLPLK
>Mature_337_residues
GSLDEKISVVKAKPWLVSLVCAVFIAYPNLAWIFCDMSYLAPNDHQGFLLFFGFRFLYFWGLIWFLLKSNLRHEDCTSFF
ERLLWNALYVSGGFVVYKLISFLTISYDRFLSIIIFQFIVLALLCTLIGYIQMLYHNQREKDQLIENLRVENLQSRCDAL
VNQINPHFFFNSLNGISSLIRKKNDENTLLYVTKLSDIFRYILQSDKKNLVPLSEELAFIEAFQHVMVVRFANKLTFTIE
VPEDKRNLRIPVLSLLPLVENVTVHNIIDSEHRMDILIRLNERMELVVSNPIYPKLTLPDTNGTGLKNLENRFLLLMNKQ
IRVESDEDEFQVYLPLK

Specific function: Member of the two-component regulatory system lytR/lytS that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=169, Percent_Identity=31.9526627218935, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788723, Length=205, Percent_Identity=31.7073170731707, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39637; Mature: 39506

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSLDEKISVVKAKPWLVSLVCAVFIAYPNLAWIFCDMSYLAPNDHQGFLLFFGFRFLYF
CCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCHHHHHHHHHHHH
WGLIWFLLKSNLRHEDCTSFFERLLWNALYVSGGFVVYKLISFLTISYDRFLSIIIFQFI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VLALLCTLIGYIQMLYHNQREKDQLIENLRVENLQSRCDALVNQINPHFFFNSLNGISSL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IRKKNDENTLLYVTKLSDIFRYILQSDKKNLVPLSEELAFIEAFQHVMVVRFANKLTFTI
HHCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEE
EVPEDKRNLRIPVLSLLPLVENVTVHNIIDSEHRMDILIRLNERMELVVSNPIYPKLTLP
ECCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCEEEEEEECCCEEEEECCCCCCEEECC
DTNGTGLKNLENRFLLLMNKQIRVESDEDEFQVYLPLK
CCCCCCCHHHCCCEEEEECCCEEECCCCCCEEEEECCC
>Mature Secondary Structure 
GSLDEKISVVKAKPWLVSLVCAVFIAYPNLAWIFCDMSYLAPNDHQGFLLFFGFRFLYF
CCCHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCHHHHHHHHHHHH
WGLIWFLLKSNLRHEDCTSFFERLLWNALYVSGGFVVYKLISFLTISYDRFLSIIIFQFI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VLALLCTLIGYIQMLYHNQREKDQLIENLRVENLQSRCDALVNQINPHFFFNSLNGISSL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IRKKNDENTLLYVTKLSDIFRYILQSDKKNLVPLSEELAFIEAFQHVMVVRFANKLTFTI
HHCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEE
EVPEDKRNLRIPVLSLLPLVENVTVHNIIDSEHRMDILIRLNERMELVVSNPIYPKLTLP
ECCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCEEEEEEECCCEEEEECCCCCCEEECC
DTNGTGLKNLENRFLLLMNKQIRVESDEDEFQVYLPLK
CCCCCCCHHHCCCEEEEECCCEEECCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA