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The map label for this gene is aroB

Identifier: 150009140

GI number: 150009140

Start: 3008583

End: 3009644

Strand: Reverse

Name: aroB

Synonym: BDI_2542

Alternate gene names: 150009140

Gene position: 3009644-3008583 (Counterclockwise)

Preceding gene: 150009141

Following gene: 150009138

Centisome position: 62.55

GC content: 45.1

Gene sequence:

>1062_bases
ATGTCAGAGCAAAAAGTGGTTATTTGCAAGGACCTGAAATCGGAACTGCAAGATTTTCTCTCCTCTCTAAAATACGATAA
GTTGTTCATCCTTATGGATACGAATACCAAAGAGAAATGTTTTCCCTTGGTAGAGGATATACCGGCCTTTCAAAAGGCGC
CGATTCTCGTGATGGAAGCGGGTGATATGAATAAGGGTTTTGTCTCATTAGCCCAGATATGGACAGCTTTGTCGAATGAG
GGGGCTTCCCGTAACTCCTTGCTGGTGAATTTGGGCGGCGGTATGATTACGGATATGGGTGGTTTTGCCGGCGCTACTTT
CAAGCGGGGCATCCGTACGATCAATATCCCTACGACCTTGATGGCGTCCGTCGATGCTGCGGTTGGCGGTAAGACGGGTA
TAAACTTCAATGGGTTGAAGAACGAGGTCGGTTCTTTTTATCCCCCCTTGTGTGTATTCATCGATTGCGATTTTTTGCGC
ACGTTGGATCGCGATAATATCCTTTCCGGTTATGCGGAGATGATCAAGCACGGGTTGATTAGTTCGATGGAGAATTATGC
GTCTGTCATGCTTTTTGATATCGACACCATGAATTATTCGTATTTGAATAGTTTGGTAGGCCAGTCGGTCGCCGTGAAAG
AGCGGATCGTAGAGGAAGATCCCAAGGAACAAGGTATTCGTAAGGCATTGAATTTCGGTCATACGATCGGCCACGCTTTC
GAGAGCTTGTCTTTCCTGAAAATGCGTCCGATCTTGCATGGTCATGCGGTAGCGGCGGGTATCGTGAGCGAGCTTTACCT
CTCGCATAAGCTGTGTGGCTTCCCGATGGAGAAATTGAGTCAAGTCGTTTATTATATAAAAGAGTATTATCCGGCGCTCT
TCTTTGACTGCACGGACTACGATACCTTATATGAGTTAATGACACATGATAAAAAGAATGAGGGCGGTATCATCAACTTC
ACTTTACTGAAAAATGTAGGGGATGTCCGTATCAACCAATCGGTCACCAAGGAAAAAATCTTGGAGTCTCTTGATTTTTA
TCGTGAAAGTTTTGGCATTTAA

Upstream 100 bases:

>100_bases
GATCGAATAAGAATTCCATCCGAAGGAATTTTTTTATGTCGTTTTGATAATCGGAATACATGTTTTACCTTTGTGGTCTA
AGGTTTTAAATAAAAAAGAT

Downstream 100 bases:

>100_bases
CGGAAAAAAACTACCTTTGCACCCGTAAAATAAAAGCGGGATGTAGCTCAGCCCGGTTAGAGTACGCGTCTGGGGGGCGT
GTGGTCGCTGGTTCGAATCC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSEQKVVICKDLKSELQDFLSSLKYDKLFILMDTNTKEKCFPLVEDIPAFQKAPILVMEAGDMNKGFVSLAQIWTALSNE
GASRNSLLVNLGGGMITDMGGFAGATFKRGIRTINIPTTLMASVDAAVGGKTGINFNGLKNEVGSFYPPLCVFIDCDFLR
TLDRDNILSGYAEMIKHGLISSMENYASVMLFDIDTMNYSYLNSLVGQSVAVKERIVEEDPKEQGIRKALNFGHTIGHAF
ESLSFLKMRPILHGHAVAAGIVSELYLSHKLCGFPMEKLSQVVYYIKEYYPALFFDCTDYDTLYELMTHDKKNEGGIINF
TLLKNVGDVRINQSVTKEKILESLDFYRESFGI

Sequences:

>Translated_353_residues
MSEQKVVICKDLKSELQDFLSSLKYDKLFILMDTNTKEKCFPLVEDIPAFQKAPILVMEAGDMNKGFVSLAQIWTALSNE
GASRNSLLVNLGGGMITDMGGFAGATFKRGIRTINIPTTLMASVDAAVGGKTGINFNGLKNEVGSFYPPLCVFIDCDFLR
TLDRDNILSGYAEMIKHGLISSMENYASVMLFDIDTMNYSYLNSLVGQSVAVKERIVEEDPKEQGIRKALNFGHTIGHAF
ESLSFLKMRPILHGHAVAAGIVSELYLSHKLCGFPMEKLSQVVYYIKEYYPALFFDCTDYDTLYELMTHDKKNEGGIINF
TLLKNVGDVRINQSVTKEKILESLDFYRESFGI
>Mature_352_residues
SEQKVVICKDLKSELQDFLSSLKYDKLFILMDTNTKEKCFPLVEDIPAFQKAPILVMEAGDMNKGFVSLAQIWTALSNEG
ASRNSLLVNLGGGMITDMGGFAGATFKRGIRTINIPTTLMASVDAAVGGKTGINFNGLKNEVGSFYPPLCVFIDCDFLRT
LDRDNILSGYAEMIKHGLISSMENYASVMLFDIDTMNYSYLNSLVGQSVAVKERIVEEDPKEQGIRKALNFGHTIGHAFE
SLSFLKMRPILHGHAVAAGIVSELYLSHKLCGFPMEKLSQVVYYIKEYYPALFFDCTDYDTLYELMTHDKKNEGGIINFT
LLKNVGDVRINQSVTKEKILESLDFYRESFGI

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=297, Percent_Identity=32.996632996633, Blast_Score=146, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6320332, Length=324, Percent_Identity=32.0987654320988, Blast_Score=152, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_PARD8 (A6LEZ7)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001303883.1
- ProteinModelPortal:   A6LEZ7
- SMR:   A6LEZ7
- STRING:   A6LEZ7
- GeneID:   5307691
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_2542
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   YINEFAL
- ProtClustDB:   CLSK823726
- BioCyc:   PDIS435591:BDI_2542-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39407; Mature: 39276

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQKVVICKDLKSELQDFLSSLKYDKLFILMDTNTKEKCFPLVEDIPAFQKAPILVMEA
CCCCCEEHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCHHCCCEEEEEC
GDMNKGFVSLAQIWTALSNEGASRNSLLVNLGGGMITDMGGFAGATFKRGIRTINIPTTL
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEECCCCCCCHHHHCCCEEECCCHHH
MASVDAAVGGKTGINFNGLKNEVGSFYPPLCVFIDCDFLRTLDRDNILSGYAEMIKHGLI
HHHHHHHCCCCCCCCCCCHHHHHCCCCCCCEEEEECHHHHHCCCCHHHHHHHHHHHHHHH
SSMENYASVMLFDIDTMNYSYLNSLVGQSVAVKERIVEEDPKEQGIRKALNFGHTIGHAF
HHHHHHHEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ESLSFLKMRPILHGHAVAAGIVSELYLSHKLCGFPMEKLSQVVYYIKEYYPALFFDCTDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEECCCCH
DTLYELMTHDKKNEGGIINFTLLKNVGDVRINQSVTKEKILESLDFYRESFGI
HHHHHHHHCCCCCCCCEEEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEQKVVICKDLKSELQDFLSSLKYDKLFILMDTNTKEKCFPLVEDIPAFQKAPILVMEA
CCCCEEHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCHHCCCEEEEEC
GDMNKGFVSLAQIWTALSNEGASRNSLLVNLGGGMITDMGGFAGATFKRGIRTINIPTTL
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEECCCCCCCHHHHCCCEEECCCHHH
MASVDAAVGGKTGINFNGLKNEVGSFYPPLCVFIDCDFLRTLDRDNILSGYAEMIKHGLI
HHHHHHHCCCCCCCCCCCHHHHHCCCCCCCEEEEECHHHHHCCCCHHHHHHHHHHHHHHH
SSMENYASVMLFDIDTMNYSYLNSLVGQSVAVKERIVEEDPKEQGIRKALNFGHTIGHAF
HHHHHHHEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ESLSFLKMRPILHGHAVAAGIVSELYLSHKLCGFPMEKLSQVVYYIKEYYPALFFDCTDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEECCCCH
DTLYELMTHDKKNEGGIINFTLLKNVGDVRINQSVTKEKILESLDFYRESFGI
HHHHHHHHCCCCCCCCEEEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA