Click here to switch to the map view.

The map label for this gene is wzb [C]

Identifier: 150008902

GI number: 150008902

Start: 2691438

End: 2691941

Strand: Reverse

Name: wzb [C]

Synonym: BDI_2297

Alternate gene names: 150008902

Gene position: 2691941-2691438 (Counterclockwise)

Preceding gene: 150008903

Following gene: 150008900

Centisome position: 55.95

GC content: 51.59

Gene sequence:

>504_bases
ATGGAAAGGAGCTTAGTGATGAAGGAGGAGAAGGTACGGTTGTTGTTTGTGTGCTTGGGGAATATATGTCGCTCTCCGTC
GGCGGAGGCAGTAATGAAGAGGTTGGTGAAGGATGCGGGATTGGGAGATCGGATTGAGATCGATTCCGCCGGGATCACCG
GGTATCATGAAGGAGACCGGGCGGATTCACGGATGCGGGCGCATGCGGCCCGTAGGGGATATGTGTTGGATTCGATCTCC
CGTCCGGTACGTCAGTGGGACTTCCATGACTTCGATTTGATTATCGGCATGGACGACCAAAATATAACGGACTTGAAACG
GATGGCTCCCGATCTGGAATCCGTCGCTAAGATACATCGGATGACTGAGTTCTCCCGGAATAAGTTGTACGATCACGTCC
CGGATCCTTATTATAGCGGTGCCGAGGGTTTCGAGCTGGTCTTGGATCTATTGGAAGACGCTTGCGCCGGGTTGTTGGAA
TATTGTAAAGACCATTTGTCTTAA

Upstream 100 bases:

>100_bases
ACTGAGATGCAAGGATATGTACCGTTTAAGCAGTTGCTGGTTCATTATGATGTGGACCCGGCTTGAGAATTGAAAATGGA
GAATTGAAAATTGAAAATTA

Downstream 100 bases:

>100_bases
GTTCGGGGCGAAGCCGGATCAGTAAAGAGGTTGTTACGGCTATCGTTCAACTTCTTTTACTAACCATTTGATTTCGTTAT
CGGTAATACTTTCACGCTCT

Product: putative protein-tyrosine-phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MERSLVMKEEKVRLLFVCLGNICRSPSAEAVMKRLVKDAGLGDRIEIDSAGITGYHEGDRADSRMRAHAARRGYVLDSIS
RPVRQWDFHDFDLIIGMDDQNITDLKRMAPDLESVAKIHRMTEFSRNKLYDHVPDPYYSGAEGFELVLDLLEDACAGLLE
YCKDHLS

Sequences:

>Translated_167_residues
MERSLVMKEEKVRLLFVCLGNICRSPSAEAVMKRLVKDAGLGDRIEIDSAGITGYHEGDRADSRMRAHAARRGYVLDSIS
RPVRQWDFHDFDLIIGMDDQNITDLKRMAPDLESVAKIHRMTEFSRNKLYDHVPDPYYSGAEGFELVLDLLEDACAGLLE
YCKDHLS
>Mature_167_residues
MERSLVMKEEKVRLLFVCLGNICRSPSAEAVMKRLVKDAGLGDRIEIDSAGITGYHEGDRADSRMRAHAARRGYVLDSIS
RPVRQWDFHDFDLIIGMDDQNITDLKRMAPDLESVAKIHRMTEFSRNKLYDHVPDPYYSGAEGFELVLDLLEDACAGLLE
YCKDHLS

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=156, Percent_Identity=36.5384615384615, Blast_Score=104, Evalue=4e-23,
Organism=Homo sapiens, GI6005988, Length=156, Percent_Identity=34.6153846153846, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI96304457, Length=83, Percent_Identity=40.9638554216867, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325330, Length=144, Percent_Identity=34.0277777777778, Blast_Score=96, Evalue=3e-21,
Organism=Drosophila melanogaster, GI78706766, Length=149, Percent_Identity=41.6107382550336, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI78706768, Length=149, Percent_Identity=41.6107382550336, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI78706764, Length=126, Percent_Identity=42.0634920634921, Blast_Score=102, Evalue=9e-23,
Organism=Drosophila melanogaster, GI78706770, Length=157, Percent_Identity=36.3057324840764, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI78706772, Length=157, Percent_Identity=36.3057324840764, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI78711846, Length=155, Percent_Identity=32.9032258064516, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 19006; Mature: 19006

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERSLVMKEEKVRLLFVCLGNICRSPSAEAVMKRLVKDAGLGDRIEIDSAGITGYHEGDR
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCC
ADSRMRAHAARRGYVLDSISRPVRQWDFHDFDLIIGMDDQNITDLKRMAPDLESVAKIHR
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCHHHHHHHHH
MTEFSRNKLYDHVPDPYYSGAEGFELVLDLLEDACAGLLEYCKDHLS
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MERSLVMKEEKVRLLFVCLGNICRSPSAEAVMKRLVKDAGLGDRIEIDSAGITGYHEGDR
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCC
ADSRMRAHAARRGYVLDSISRPVRQWDFHDFDLIIGMDDQNITDLKRMAPDLESVAKIHR
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCHHHHHHHHH
MTEFSRNKLYDHVPDPYYSGAEGFELVLDLLEDACAGLLEYCKDHLS
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]