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The map label for this gene is pepC [H]

Identifier: 150008892

GI number: 150008892

Start: 2677007

End: 2678410

Strand: Direct

Name: pepC [H]

Synonym: BDI_2287

Alternate gene names: 150008892

Gene position: 2677007-2678410 (Clockwise)

Preceding gene: 150008891

Following gene: 150008895

Centisome position: 55.64

GC content: 47.86

Gene sequence:

>1404_bases
ATGAAGCAAAAGAATTTATGGATAGCGGCCTTGGCTTTAGGCATCACGCTATCGGCTCACGGACAACAAAGTGGTGGAGG
CATCTCACCCACGATGTTGCAGCAAATCAAACAGTCTTATCAAGGAACGCCGACCGATAAGGCGATCCGTAACGCGATCA
CCAATAACGACATCAACAAGCTTGCCGTTAATGGGGAGAGCAAGAACAATTTGGATACTTACTTCTCCAATAAGGTAGAG
AGCAAAGGGATCTCCAACCAACGTTCCTCGGGCCGTTGCTGGCTTTTCACGGGATTGAACGTGTTCCGTGCGCAGGCCAT
CGCCAAATATGACATGGGAGACTTTCAATTCTCCCAGAATTATTCTTTCTTCTGGGATCAATTGGAGAAAGCGAACCTTT
TCTTACAGGGCATCATCGATACTCGTCTGAAACCAATGGACGACAAGATGGTGGAATGGTTATTCAAGAACCCGATCGGA
GACGGAGGGCAGTTCACGGGTGTCTCCGATATCTTGACCAAATATGGCGTGGTTCCCGCCGAAGTCATGGTAGAGACCAA
CAGCAGCAACAGTACCGGACGCATGAGCAACCTGATCGGATTAAAGCTGAAAGAATACGGCTTGCAACTTCGTGACCTGT
CTACGACCAAAGGCACGACCGTAGCGGATCTGGAGAAAAAGAAAACAGAGATGCTAGGTACGATTTACCGTATGCTCGTA
TTGAACTTGGGAGAGCCGCCTACGAAATTCACGTGGACTCGCAAAGACGCTAAAGGGAATCCGGTAGAGACGAAGGAATA
TACGCCTCAGTCCTTCTTCCAAGAATATATCGGGGACGATTTGAAAAACAACTATGTCATGTTGATGAACGATCCGAGCC
GCGATTATTATAAGTTGTATGAGATCGATTACGACCGCCACGCTTACGATGGCAAGAACTGGACGTACGTAAACCTTCCG
ATCGAGGATATCAAACAAATGGCTATCGCTTCCATCAAGGACAGCACCATGATGTATTTCTCTTGCGACGTGGGCAAGTT
CTTCGATCGTGACAGAGGTATTCTGGATGTAAACTTCTACGATTACGGTTCATTGCTGGGTACGACTTTCGGCATGGATA
AGAAACAACGTATCCAAACATTCGCCAGCGGTTCCTCACACGCCATGACCTTGATGGCAGTTGACCTCGACGCGAATGGA
AAGCCGAAGAAATGGATGGTTGAGAATAGTTGGGGTCCCGGAGCGAACGCCGGCCACCTCATCATGACAGACCAATGGTT
TAATGAGTATATGTTCCGTCTGGTAGTCAACAAAAAGTACATCACGGATCAAGTAAAAGAGATCTTGAAACAAACACCGA
CTCGCCTTCCCGCTTGGGACCCGATGTTCGCTGAAGAGGATTAA

Upstream 100 bases:

>100_bases
ATCACTACCCGCACCAGACGGTACGGTATGGAATATCCGGCAAGACGGTCTGGTATGGCCTAAAAAGAAATAACACAATT
TATTAATCAACTAAAATATC

Downstream 100 bases:

>100_bases
AATAAAACACGGATGAGATAGACAACGCGAATCGTTCAATTACCAATCCGTACATCTATCTCATCCGTATTCCATTGCTA
TATCAAAAGAGTCTGGGCAT

Product: putative aminopeptidase C

Products: NA

Alternate protein names: Bleomycin hydrolase [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKQKNLWIAALALGITLSAHGQQSGGGISPTMLQQIKQSYQGTPTDKAIRNAITNNDINKLAVNGESKNNLDTYFSNKVE
SKGISNQRSSGRCWLFTGLNVFRAQAIAKYDMGDFQFSQNYSFFWDQLEKANLFLQGIIDTRLKPMDDKMVEWLFKNPIG
DGGQFTGVSDILTKYGVVPAEVMVETNSSNSTGRMSNLIGLKLKEYGLQLRDLSTTKGTTVADLEKKKTEMLGTIYRMLV
LNLGEPPTKFTWTRKDAKGNPVETKEYTPQSFFQEYIGDDLKNNYVMLMNDPSRDYYKLYEIDYDRHAYDGKNWTYVNLP
IEDIKQMAIASIKDSTMMYFSCDVGKFFDRDRGILDVNFYDYGSLLGTTFGMDKKQRIQTFASGSSHAMTLMAVDLDANG
KPKKWMVENSWGPGANAGHLIMTDQWFNEYMFRLVVNKKYITDQVKEILKQTPTRLPAWDPMFAEED

Sequences:

>Translated_467_residues
MKQKNLWIAALALGITLSAHGQQSGGGISPTMLQQIKQSYQGTPTDKAIRNAITNNDINKLAVNGESKNNLDTYFSNKVE
SKGISNQRSSGRCWLFTGLNVFRAQAIAKYDMGDFQFSQNYSFFWDQLEKANLFLQGIIDTRLKPMDDKMVEWLFKNPIG
DGGQFTGVSDILTKYGVVPAEVMVETNSSNSTGRMSNLIGLKLKEYGLQLRDLSTTKGTTVADLEKKKTEMLGTIYRMLV
LNLGEPPTKFTWTRKDAKGNPVETKEYTPQSFFQEYIGDDLKNNYVMLMNDPSRDYYKLYEIDYDRHAYDGKNWTYVNLP
IEDIKQMAIASIKDSTMMYFSCDVGKFFDRDRGILDVNFYDYGSLLGTTFGMDKKQRIQTFASGSSHAMTLMAVDLDANG
KPKKWMVENSWGPGANAGHLIMTDQWFNEYMFRLVVNKKYITDQVKEILKQTPTRLPAWDPMFAEED
>Mature_467_residues
MKQKNLWIAALALGITLSAHGQQSGGGISPTMLQQIKQSYQGTPTDKAIRNAITNNDINKLAVNGESKNNLDTYFSNKVE
SKGISNQRSSGRCWLFTGLNVFRAQAIAKYDMGDFQFSQNYSFFWDQLEKANLFLQGIIDTRLKPMDDKMVEWLFKNPIG
DGGQFTGVSDILTKYGVVPAEVMVETNSSNSTGRMSNLIGLKLKEYGLQLRDLSTTKGTTVADLEKKKTEMLGTIYRMLV
LNLGEPPTKFTWTRKDAKGNPVETKEYTPQSFFQEYIGDDLKNNYVMLMNDPSRDYYKLYEIDYDRHAYDGKNWTYVNLP
IEDIKQMAIASIKDSTMMYFSCDVGKFFDRDRGILDVNFYDYGSLLGTTFGMDKKQRIQTFASGSSHAMTLMAVDLDANG
KPKKWMVENSWGPGANAGHLIMTDQWFNEYMFRLVVNKKYITDQVKEILKQTPTRLPAWDPMFAEED

Specific function: Unknown

COG id: COG3579

COG function: function code E; Aminopeptidase C

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C1 family [H]

Homologues:

Organism=Homo sapiens, GI4557367, Length=452, Percent_Identity=35.8407079646018, Blast_Score=311, Evalue=1e-84,
Organism=Saccharomyces cerevisiae, GI6324090, Length=420, Percent_Identity=30.7142857142857, Blast_Score=213, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24640588, Length=457, Percent_Identity=31.5098468271335, Blast_Score=252, Evalue=5e-67,
Organism=Drosophila melanogaster, GI161077632, Length=457, Percent_Identity=31.5098468271335, Blast_Score=252, Evalue=5e-67,
Organism=Drosophila melanogaster, GI161077630, Length=363, Percent_Identity=32.5068870523416, Blast_Score=204, Evalue=7e-53,
Organism=Drosophila melanogaster, GI20130175, Length=461, Percent_Identity=25.1626898047722, Blast_Score=152, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000169
- InterPro:   IPR004134 [H]

Pfam domain/function: PF03051 Peptidase_C1_2 [H]

EC number: =3.4.22.40 [H]

Molecular weight: Translated: 53130; Mature: 53130

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS00626 RCC1_2 ; PS00139 THIOL_PROTEASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQKNLWIAALALGITLSAHGQQSGGGISPTMLQQIKQSYQGTPTDKAIRNAITNNDINK
CCCCCEEEEEEEHHEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCE
LAVNGESKNNLDTYFSNKVESKGISNQRSSGRCWLFTGLNVFRAQAIAKYDMGDFQFSQN
EEECCCCCCCCHHHHHCHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCEEECCC
YSFFWDQLEKANLFLQGIIDTRLKPMDDKMVEWLFKNPIGDGGQFTGVSDILTKYGVVPA
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCE
EVMVETNSSNSTGRMSNLIGLKLKEYGLQLRDLSTTKGTTVADLEKKKTEMLGTIYRMLV
EEEEEECCCCCCCHHHHHHCEEEHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
LNLGEPPTKFTWTRKDAKGNPVETKEYTPQSFFQEYIGDDLKNNYVMLMNDPSRDYYKLY
HHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCHHCCCEEEEEECCCCCEEEEE
EIDYDRHAYDGKNWTYVNLPIEDIKQMAIASIKDSTMMYFSCDVGKFFDRDRGILDVNFY
EECCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCCEEEEECH
DYGSLLGTTFGMDKKQRIQTFASGSSHAMTLMAVDLDANGKPKKWMVENSWGPGANAGHL
HHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEEEECCCCCCCCCCEE
IMTDQWFNEYMFRLVVNKKYITDQVKEILKQTPTRLPAWDPMFAEED
EEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKQKNLWIAALALGITLSAHGQQSGGGISPTMLQQIKQSYQGTPTDKAIRNAITNNDINK
CCCCCEEEEEEEHHEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCE
LAVNGESKNNLDTYFSNKVESKGISNQRSSGRCWLFTGLNVFRAQAIAKYDMGDFQFSQN
EEECCCCCCCCHHHHHCHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCEEECCC
YSFFWDQLEKANLFLQGIIDTRLKPMDDKMVEWLFKNPIGDGGQFTGVSDILTKYGVVPA
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCE
EVMVETNSSNSTGRMSNLIGLKLKEYGLQLRDLSTTKGTTVADLEKKKTEMLGTIYRMLV
EEEEEECCCCCCCHHHHHHCEEEHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
LNLGEPPTKFTWTRKDAKGNPVETKEYTPQSFFQEYIGDDLKNNYVMLMNDPSRDYYKLY
HHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCHHCCCEEEEEECCCCCEEEEE
EIDYDRHAYDGKNWTYVNLPIEDIKQMAIASIKDSTMMYFSCDVGKFFDRDRGILDVNFY
EECCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCCEEEEECH
DYGSLLGTTFGMDKKQRIQTFASGSSHAMTLMAVDLDANGKPKKWMVENSWGPGANAGHL
HHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEEEECCCCCCCCCCEE
IMTDQWFNEYMFRLVVNKKYITDQVKEILKQTPTRLPAWDPMFAEED
EEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7851736 [H]