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The map label for this gene is carD [H]

Identifier: 150008861

GI number: 150008861

Start: 2639869

End: 2641056

Strand: Reverse

Name: carD [H]

Synonym: BDI_2251

Alternate gene names: 150008861

Gene position: 2641056-2639869 (Counterclockwise)

Preceding gene: 150008862

Following gene: 150008859

Centisome position: 54.89

GC content: 48.74

Gene sequence:

>1188_bases
ATGTTAGACTTTAACAATACCGAGATCGCTTTCTCGTCGAAGTCGCGGGGAGAACTACAAAATGCTTACTGGCTTTTTAA
TACGATAAAATATCCTTGGTTGGTAAAATGCGCTAAAGTAGCCACGAGTATAGCCTTGAAAATACATTTCCCGCTGGCTT
GGGCGGTGAAGCCTACCTTATATAAACAGTTCGTTGGGGGAGAAACTTTACAAGACTGTTCCGCAGCCATCAACCACTTG
ATGAAATACAACGTGAAATCGACGCTCGATTATTCGGCGGAGAGCGAGCAGACCCCGGAGGGCATACAGGCGACTTTCGA
GGAAACCTTGCGCTCGATAGATTTTGCGAAAGGAAATACGAATCTGGCCTATGCCGTATTCAAACCATCCACGATCACGA
CCGATGAGTTACTGGCCAAAGCTTCCGAGAAACGGGAAGAGCTTACGATAGACGATGTCCGGCATTTCCGCGAGTTCCGC
GAGCGTTTTATGGCGCTTTGCCAACGGGCTTACGATAACGACGTACGTATTTTAGTGGATGCGGAGGATTATTGTTTCCA
AGATGCCATTGATGCGTTGACCGATGAGGCGATGCGTAAGTTCAACAAGAAACGTGCGATCGTATTCGCTACCTTGCAAA
TGTATCGTCATGACCGGATGCCTTATCTGCGTCGTATCTACGATGATGCCGTGGCGAAAGGTTATATTGCGGGCGTGAAA
TTCGTGCGCGGGGCTTATATGGAAGCGGAGCGTGCCCGTGCGGCGGCGTTGGATTATCCCGATCCGATTTGTAAAGATAA
GCAGGCCACGGACGAGAATTATGATGCGGCGGTCCGTTTCACCATGGATCATTTAGATCGTTTTGAGATGTTTATGGGAA
CTCATAATGAGGAGAGTAATTATAAGTTGGCGAAATTGATGGACGAGAAGGGGATCGCCCGCGATGACTCCCGTGTTTTC
TTTGCGCAGCTATTGGGAATGAGCGATAATATTTCCTTCAATTTAGCCCATGCGGGATATAACGTAACCAAATACGTACC
GTACGCCTCGGTAAGGGATGTACTGCCGTATTTGATCCGGCGTGCGGAAGAGAATACTTCTGTCGCGGGGCAGACCAGCC
GGGAACTCCGGATGTTGGAGATGGAAATGACTAGGCGGAAAGAACATAAACCTGCCGAGGGCAGGTAA

Upstream 100 bases:

>100_bases
TGAGAAATAATTGTCATAATTAAGAAATACCAACTGATTGTGGGGGAGACGGGGCGTGCCCCGTCTCTACGCTATGACGT
TACCTTTATCTACATACAAT

Downstream 100 bases:

>100_bases
AGTAGTTTGTCAGCATATTTCGGGGCGTATTGGTGCTGGCAAACTACTTTGTCTGCCTATTTTTATTTACTGGCCTTCAG
TCCCCGGATCACGGAAGAGG

Product: proline dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MLDFNNTEIAFSSKSRGELQNAYWLFNTIKYPWLVKCAKVATSIALKIHFPLAWAVKPTLYKQFVGGETLQDCSAAINHL
MKYNVKSTLDYSAESEQTPEGIQATFEETLRSIDFAKGNTNLAYAVFKPSTITTDELLAKASEKREELTIDDVRHFREFR
ERFMALCQRAYDNDVRILVDAEDYCFQDAIDALTDEAMRKFNKKRAIVFATLQMYRHDRMPYLRRIYDDAVAKGYIAGVK
FVRGAYMEAERARAAALDYPDPICKDKQATDENYDAAVRFTMDHLDRFEMFMGTHNEESNYKLAKLMDEKGIARDDSRVF
FAQLLGMSDNISFNLAHAGYNVTKYVPYASVRDVLPYLIRRAEENTSVAGQTSRELRMLEMEMTRRKEHKPAEGR

Sequences:

>Translated_395_residues
MLDFNNTEIAFSSKSRGELQNAYWLFNTIKYPWLVKCAKVATSIALKIHFPLAWAVKPTLYKQFVGGETLQDCSAAINHL
MKYNVKSTLDYSAESEQTPEGIQATFEETLRSIDFAKGNTNLAYAVFKPSTITTDELLAKASEKREELTIDDVRHFREFR
ERFMALCQRAYDNDVRILVDAEDYCFQDAIDALTDEAMRKFNKKRAIVFATLQMYRHDRMPYLRRIYDDAVAKGYIAGVK
FVRGAYMEAERARAAALDYPDPICKDKQATDENYDAAVRFTMDHLDRFEMFMGTHNEESNYKLAKLMDEKGIARDDSRVF
FAQLLGMSDNISFNLAHAGYNVTKYVPYASVRDVLPYLIRRAEENTSVAGQTSRELRMLEMEMTRRKEHKPAEGR
>Mature_395_residues
MLDFNNTEIAFSSKSRGELQNAYWLFNTIKYPWLVKCAKVATSIALKIHFPLAWAVKPTLYKQFVGGETLQDCSAAINHL
MKYNVKSTLDYSAESEQTPEGIQATFEETLRSIDFAKGNTNLAYAVFKPSTITTDELLAKASEKREELTIDDVRHFREFR
ERFMALCQRAYDNDVRILVDAEDYCFQDAIDALTDEAMRKFNKKRAIVFATLQMYRHDRMPYLRRIYDDAVAKGYIAGVK
FVRGAYMEAERARAAALDYPDPICKDKQATDENYDAAVRFTMDHLDRFEMFMGTHNEESNYKLAKLMDEKGIARDDSRVF
FAQLLGMSDNISFNLAHAGYNVTKYVPYASVRDVLPYLIRRAEENTSVAGQTSRELRMLEMEMTRRKEHKPAEGR

Specific function: Unknown

COG id: COG0506

COG function: function code E; Proline dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the proline oxidase family [H]

Homologues:

Organism=Homo sapiens, GI183227691, Length=218, Percent_Identity=42.2018348623853, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI10864043, Length=424, Percent_Identity=30.4245283018868, Blast_Score=155, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI71981541, Length=246, Percent_Identity=38.2113821138211, Blast_Score=164, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6323171, Length=279, Percent_Identity=28.3154121863799, Blast_Score=90, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24643717, Length=273, Percent_Identity=37.7289377289377, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI45556158, Length=273, Percent_Identity=37.7289377289377, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI45556169, Length=273, Percent_Identity=37.7289377289377, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI45556180, Length=273, Percent_Identity=37.7289377289377, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24643719, Length=273, Percent_Identity=37.7289377289377, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24643721, Length=273, Percent_Identity=37.7289377289377, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24643715, Length=273, Percent_Identity=37.7289377289377, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24643723, Length=274, Percent_Identity=37.5912408759124, Blast_Score=172, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002872
- InterPro:   IPR015659 [H]

Pfam domain/function: PF01619 Pro_dh [H]

EC number: NA

Molecular weight: Translated: 45576; Mature: 45576

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDFNNTEIAFSSKSRGELQNAYWLFNTIKYPWLVKCAKVATSIALKIHFPLAWAVKPTL
CCCCCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEEECCCHHHHHHHH
YKQFVGGETLQDCSAAINHLMKYNVKSTLDYSAESEQTPEGIQATFEETLRSIDFAKGNT
HHHHHCCCHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
NLAYAVFKPSTITTDELLAKASEKREELTIDDVRHFREFRERFMALCQRAYDNDVRILVD
CEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
AEDYCFQDAIDALTDEAMRKFNKKRAIVFATLQMYRHDRMPYLRRIYDDAVAKGYIAGVK
CHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FVRGAYMEAERARAAALDYPDPICKDKQATDENYDAAVRFTMDHLDRFEMFMGTHNEESN
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCC
YKLAKLMDEKGIARDDSRVFFAQLLGMSDNISFNLAHAGYNVTKYVPYASVRDVLPYLIR
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCHHEECCCHHHHHHHHHHHH
RAEENTSVAGQTSRELRMLEMEMTRRKEHKPAEGR
HCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLDFNNTEIAFSSKSRGELQNAYWLFNTIKYPWLVKCAKVATSIALKIHFPLAWAVKPTL
CCCCCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEEECCCHHHHHHHH
YKQFVGGETLQDCSAAINHLMKYNVKSTLDYSAESEQTPEGIQATFEETLRSIDFAKGNT
HHHHHCCCHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
NLAYAVFKPSTITTDELLAKASEKREELTIDDVRHFREFRERFMALCQRAYDNDVRILVD
CEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
AEDYCFQDAIDALTDEAMRKFNKKRAIVFATLQMYRHDRMPYLRRIYDDAVAKGYIAGVK
CHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FVRGAYMEAERARAAALDYPDPICKDKQATDENYDAAVRFTMDHLDRFEMFMGTHNEESN
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCC
YKLAKLMDEKGIARDDSRVFFAQLLGMSDNISFNLAHAGYNVTKYVPYASVRDVLPYLIR
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCHHEECCCHHHHHHHHHHHH
RAEENTSVAGQTSRELRMLEMEMTRRKEHKPAEGR
HCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9402024 [H]