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The map label for this gene is ugd [H]

Identifier: 150008825

GI number: 150008825

Start: 2603675

End: 2604922

Strand: Reverse

Name: ugd [H]

Synonym: BDI_2215

Alternate gene names: 150008825

Gene position: 2604922-2603675 (Counterclockwise)

Preceding gene: 150008826

Following gene: 150008824

Centisome position: 54.14

GC content: 39.66

Gene sequence:

>1248_bases
ATGAAAAAGTATAAAATAGCTGTAGCTGGAACAGGTTACGTCGGTCTCAGTATTGCTACTTTGTTGGCGCAGCACAATCA
GGTATTTGCAGTAGATGTAATCCAATCTAAAGTAGATGCTATCAACCAAAGGAAATCACCCATACAAGACGAATATATCG
AAAAATATTTGACCGAGAAACCATTGGATTTAACTGCTACGTTAGATGGATCAGAAGCCTACAAAAATGCCGATTTTGTC
GTTATTGCCACCCCTACCAATTACGACTCAGCAAAAAACTACTTCGATACATCTCATGTAGAAGAGGTAATCAAACTAGT
AAAACAAGTGAATCCTACGGCAATCATGATTATTAAAAGTACTATTCCTGTAGGTTTTACTGAAAAAATCAGAAAGAACT
TGAATACCGAGAATGTCTTGTTCTCACCCGAGTTTCTGCGAGAAAGTAAAGCGCTATATGACAACCTATATCCGAGCCGT
ATTATTGTCGGTCGTCCCGAGAATGATACACGCCTTGATGATGCAGCCCATACATTTGCAACATTGCTACAAGAAGGGGC
TATAAAAGAAAATATAGACACATTGTTTATGGGGTTAACCGAGGCTGAAGCGGTTAAATTGTTTGCAAATACCTACTTGG
CTCTACGAGTCTCCTACTTCAATGAATTAGATACGTATGCTGAGATGAAAGGACTGGATACAAAAGCTATTATCGATGGT
ATCAGCCTTGACCCACGCATAGGCACACACTACAACAATCCAAGTTTTGGTTATGGTGGTTATTGTCTACCGAAAGATAC
AAAACAGCTTCTGGCCAACTATGTGGATGTCCCAGAAAATCTCATTGGTGCAATTGTGGAAAGTAATCGAACTCGTAAAG
ATTTCATTGCCGACCAAGTGCTTCGGAAAGCCGGTTATTACGATTACTACAACCGTGGCGATTTCAATCCAATGAACGAA
AGACATTGCACCATTGGAGTATATCGCCTGACAATGAAATCCAACAGCGACAACTTCCGTCAGAGTAGCATACAGGGTGT
GATGAAACGAATTAAGGCAAAAGGAGCTGAGGTAATAATATATGAACCTACACTTGAAGACGGCAGCACTTTCTTTGGTA
GCAAAGTAGTAAATGATCTCACAGCTTTTAAAGCACAATCCCAGGCCATTATTGCCAACCGTTATGATAATTGTTTAGAC
GATATCAAGGAACTTGTTTATACCCGAGACATTTTCAAAAGAGATTAA

Upstream 100 bases:

>100_bases
TAGAATTTATGAAAATGCTAAGCGTTAAACGATAGGTAACTTGCCAATAGAACTATATATATTTAGCAAAATGTCAATCA
TATAGATATAATTAATTGTT

Downstream 100 bases:

>100_bases
TTTTGATATAGATGAAAACTTCACCATTGATTTCTGTAATAGTTCCTCTATATAACACAGAGAAATATATCGCTGAGTGC
ATAAAAAGTATAATAAGCCA

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MKKYKIAVAGTGYVGLSIATLLAQHNQVFAVDVIQSKVDAINQRKSPIQDEYIEKYLTEKPLDLTATLDGSEAYKNADFV
VIATPTNYDSAKNYFDTSHVEEVIKLVKQVNPTAIMIIKSTIPVGFTEKIRKNLNTENVLFSPEFLRESKALYDNLYPSR
IIVGRPENDTRLDDAAHTFATLLQEGAIKENIDTLFMGLTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLDTKAIIDG
ISLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYVDVPENLIGAIVESNRTRKDFIADQVLRKAGYYDYYNRGDFNPMNE
RHCTIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGAEVIIYEPTLEDGSTFFGSKVVNDLTAFKAQSQAIIANRYDNCLD
DIKELVYTRDIFKRD

Sequences:

>Translated_415_residues
MKKYKIAVAGTGYVGLSIATLLAQHNQVFAVDVIQSKVDAINQRKSPIQDEYIEKYLTEKPLDLTATLDGSEAYKNADFV
VIATPTNYDSAKNYFDTSHVEEVIKLVKQVNPTAIMIIKSTIPVGFTEKIRKNLNTENVLFSPEFLRESKALYDNLYPSR
IIVGRPENDTRLDDAAHTFATLLQEGAIKENIDTLFMGLTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLDTKAIIDG
ISLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYVDVPENLIGAIVESNRTRKDFIADQVLRKAGYYDYYNRGDFNPMNE
RHCTIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGAEVIIYEPTLEDGSTFFGSKVVNDLTAFKAQSQAIIANRYDNCLD
DIKELVYTRDIFKRD
>Mature_415_residues
MKKYKIAVAGTGYVGLSIATLLAQHNQVFAVDVIQSKVDAINQRKSPIQDEYIEKYLTEKPLDLTATLDGSEAYKNADFV
VIATPTNYDSAKNYFDTSHVEEVIKLVKQVNPTAIMIIKSTIPVGFTEKIRKNLNTENVLFSPEFLRESKALYDNLYPSR
IIVGRPENDTRLDDAAHTFATLLQEGAIKENIDTLFMGLTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLDTKAIIDG
ISLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYVDVPENLIGAIVESNRTRKDFIADQVLRKAGYYDYYNRGDFNPMNE
RHCTIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGAEVIIYEPTLEDGSTFFGSKVVNDLTAFKAQSQAIIANRYDNCLD
DIKELVYTRDIFKRD

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=384, Percent_Identity=28.125, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI296040438, Length=273, Percent_Identity=27.4725274725275, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI296040443, Length=368, Percent_Identity=23.0978260869565, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1788340, Length=411, Percent_Identity=58.8807785888078, Blast_Score=487, Evalue=1e-139,
Organism=Escherichia coli, GI48994968, Length=387, Percent_Identity=25.3229974160207, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560350, Length=404, Percent_Identity=27.7227722772277, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17136908, Length=400, Percent_Identity=24.75, Blast_Score=111, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 46831; Mature: 46831

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYKIAVAGTGYVGLSIATLLAQHNQVFAVDVIQSKVDAINQRKSPIQDEYIEKYLTEK
CCCEEEEEEECCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PLDLTATLDGSEAYKNADFVVIATPTNYDSAKNYFDTSHVEEVIKLVKQVNPTAIMIIKS
CCEEEEEECCHHHHCCCCEEEEECCCCCCHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEC
TIPVGFTEKIRKNLNTENVLFSPEFLRESKALYDNLYPSRIIVGRPENDTRLDDAAHTFA
CCCCCHHHHHHHCCCCCCEEECHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHH
TLLQEGAIKENIDTLFMGLTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLDTKAIIDG
HHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
ISLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYVDVPENLIGAIVESNRTRKDFIADQV
CCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHH
LRKAGYYDYYNRGDFNPMNERHCTIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGAEVII
HHHCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEE
YEPTLEDGSTFFGSKVVNDLTAFKAQSQAIIANRYDNCLDDIKELVYTRDIFKRD
ECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKYKIAVAGTGYVGLSIATLLAQHNQVFAVDVIQSKVDAINQRKSPIQDEYIEKYLTEK
CCCEEEEEEECCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PLDLTATLDGSEAYKNADFVVIATPTNYDSAKNYFDTSHVEEVIKLVKQVNPTAIMIIKS
CCEEEEEECCHHHHCCCCEEEEECCCCCCHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEC
TIPVGFTEKIRKNLNTENVLFSPEFLRESKALYDNLYPSRIIVGRPENDTRLDDAAHTFA
CCCCCHHHHHHHCCCCCCEEECHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHH
TLLQEGAIKENIDTLFMGLTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLDTKAIIDG
HHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
ISLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYVDVPENLIGAIVESNRTRKDFIADQV
CCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHH
LRKAGYYDYYNRGDFNPMNERHCTIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGAEVII
HHHCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEE
YEPTLEDGSTFFGSKVVNDLTAFKAQSQAIIANRYDNCLDDIKELVYTRDIFKRD
ECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9383197 [H]