Click here to switch to the map view.

The map label for this gene is cdd [H]

Identifier: 150008708

GI number: 150008708

Start: 2482651

End: 2483127

Strand: Reverse

Name: cdd [H]

Synonym: BDI_2098

Alternate gene names: 150008708

Gene position: 2483127-2482651 (Counterclockwise)

Preceding gene: 150008717

Following gene: 150008701

Centisome position: 51.61

GC content: 47.59

Gene sequence:

>477_bases
ATGAAAGAATTGAAATTAGAGACCCGGGTAGAGGTCTATGCGGTAGGAGAATTGGACAATATATATAGGCAATTGTACGA
GGCCGCTTTTGAAGCCTCGAAAAAAGCTTATGCTCCTTATTCCAAGTTTCATGTGGGAGCGGCGGTTCTATTGGAGAATG
GGGAGATACTTTCCGGAAATAATCAGGAAAACGCAGCCTATCCGTCTGGGCTTTGTGCGGAGCGGACCACCTTATTTTAT
GCGGGAGCACGTTATCCGGATGCGGCAGTTCAGATTTTGGCGATCGCGGCTATGAAGGATGGGGAACGTGTGGATCTTAT
CACGCCTTGTGGTGCCTGCCGGCAAGTGATGTTGGAAACCGAGCAACGTTATAACAAACCTATGAAAGTCCTTCTTTGTG
GAAAAGAGGAAGCGTATCTCGTTCCGAGCGCAACGGCCTTGTTGCCGTTTTGTTTCAGTAAGTCTGATTTGATCTGA

Upstream 100 bases:

>100_bases
ATTCTATGATGTGGGTGCGAAATTAATATATTCTTTTTATATTTATAGCCTATAAGAATTATAGTTATGTTTCTTTCAAA
ACATTAAAACAATCAAGAAA

Downstream 100 bases:

>100_bases
TAGAATAAAAAGAGGCAAGAACGATTCTCGCCCTTGCCTCTATATGTAATAATTAAGTTCGATTAGATCCCTAAAGAAGC
CTTGATCTGATTGATCTTTT

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MKELKLETRVEVYAVGELDNIYRQLYEAAFEASKKAYAPYSKFHVGAAVLLENGEILSGNNQENAAYPSGLCAERTTLFY
AGARYPDAAVQILAIAAMKDGERVDLITPCGACRQVMLETEQRYNKPMKVLLCGKEEAYLVPSATALLPFCFSKSDLI

Sequences:

>Translated_158_residues
MKELKLETRVEVYAVGELDNIYRQLYEAAFEASKKAYAPYSKFHVGAAVLLENGEILSGNNQENAAYPSGLCAERTTLFY
AGARYPDAAVQILAIAAMKDGERVDLITPCGACRQVMLETEQRYNKPMKVLLCGKEEAYLVPSATALLPFCFSKSDLI
>Mature_158_residues
MKELKLETRVEVYAVGELDNIYRQLYEAAFEASKKAYAPYSKFHVGAAVLLENGEILSGNNQENAAYPSGLCAERTTLFY
AGARYPDAAVQILAIAAMKDGERVDLITPCGACRQVMLETEQRYNKPMKVLLCGKEEAYLVPSATALLPFCFSKSDLI

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=137, Percent_Identity=43.7956204379562, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17540514, Length=134, Percent_Identity=38.0597014925373, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17551074, Length=136, Percent_Identity=33.0882352941176, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323274, Length=142, Percent_Identity=33.8028169014084, Blast_Score=66, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920920, Length=114, Percent_Identity=42.1052631578947, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24582741, Length=112, Percent_Identity=39.2857142857143, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24582744, Length=113, Percent_Identity=43.3628318584071, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 17456; Mature: 17456

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELKLETRVEVYAVGELDNIYRQLYEAAFEASKKAYAPYSKFHVGAAVLLENGEILSGN
CCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCEEEEEECCEEECCC
NQENAAYPSGLCAERTTLFYAGARYPDAAVQILAIAAMKDGERVDLITPCGACRQVMLET
CCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHEECCCCCEEEEECCCHHHHHHHHHH
EQRYNKPMKVLLCGKEEAYLVPSATALLPFCFSKSDLI
HHHCCCCEEEEEECCCCEEECCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKELKLETRVEVYAVGELDNIYRQLYEAAFEASKKAYAPYSKFHVGAAVLLENGEILSGN
CCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCEEEEEECCEEECCC
NQENAAYPSGLCAERTTLFYAGARYPDAAVQILAIAAMKDGERVDLITPCGACRQVMLET
CCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHEECCCCCEEEEECCCHHHHHHHHHH
EQRYNKPMKVLLCGKEEAYLVPSATALLPFCFSKSDLI
HHHCCCCEEEEEECCCCEEECCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2526291; 8969508; 9384377 [H]