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The map label for this gene is dcuB [H]

Identifier: 150008591

GI number: 150008591

Start: 2341524

End: 2342873

Strand: Direct

Name: dcuB [H]

Synonym: BDI_1977

Alternate gene names: 150008591

Gene position: 2341524-2342873 (Clockwise)

Preceding gene: 150008589

Following gene: 150008593

Centisome position: 48.67

GC content: 46.59

Gene sequence:

>1350_bases
TTGTCTCCAATACAAACTAAATCAAAAGAATTGCACAGCATGTTGTTACAATTAGCTTTCGTTTTAATAGCCATTATTAT
AGGTGCCCGTATCGGTGGTATCGGATTAGGCGTGTTAGGAGGTCTCGGACTCGGTATACTCACCTTTGGATTCGGGCTCC
AGCCCACTTCCCCTCCTATCGATGTCATGCTTATGATCGTTGCCGTAATAGCGGCGGCTAGTTGTATGCAAGCCGCTGGC
GGACTTGATCTTATGGTTAAGTGGGCGGAAAAATTGCTTCGCAAGAATCCTCAACGAATCACGATATTAAGCCCGCTCGT
CACCTATTTGTTTACCTTCATAGCCGGAACGGGGCATGTGGCTTATTCGGTCCTTCCGGTAATCGCCGAGGTCGCTACGG
AAACGAAGATCCGTCCCGAACGTCCGATGGCGATCGCCGTGATCGCTTCCCAGCAGGCCATTACGGCCAGTCCGATATCG
GCGGCTACGGTAGCTTTATTAAGTATGTTGTCCGGATACAATATCTCCTTGATGAATATCTTGATGATCTCTGTTCCTTG
TACCTTATTAGGTGTGTTAGCGGGAGCGATCTACTCTTTAAAGGTCGGTAAAGAGCTAGATCAAGATCCGGAATACTTAA
AGCGGGTGGCGAACCATGAGTTTAGCACGGAACATTATGAGGCGAAAGGCGTTGAAAACCAAATGAAAGCGGCCTTATCG
GTCTCTATATTTGTTCTCGCTACGATAGCGATCGTTATTTTTGGTTCTATGGAGTCCCTACGTCCGGTCTTTACCGTCGG
CACGGAAAAGGTCTCGATGCAGATGTCACATATTATTGAGGTATTAATGTTGACAGCCTCCGCTTTCATCTTATTATTTA
CAAAAACAGATGGTATCAAGGCCGCACAGGGTTCCGTTTTTTCCGCAGGTATGCAAGCGGTGGTAGCGATCTTCGGTATC
GCTTGGATGGGAGATACATTTATCGCCGGCAATATGACTGAATTAAAGGGATCTATCGAGCATATAGTTACACAGATGCC
TTGGTTATTCGGATTGGCCCTTTTCGTAATGTCCATTTTATTATTTAGCCAAGCGGCTACCATTCGTGCGTTATTGCCGC
TAGGGATCGCATTGGGAATCTCACCCTATATGTTGATCGCTTTATTCCCCGCCGTAAACGGTTATTTCTTCATCCCAAAC
TACCCGACAGTCGTAGCCGCCATCAACTTCGATCGCACGGGCACGACCCGCATCGGTAAATACATCTTGAACCATTCTTT
CATGATGCCGGGATTGATAGCGACCGGAGTTTCTGTTGGATTGGGGTTACTATTCATTCAATTCATATAA

Upstream 100 bases:

>100_bases
CAGGGAAAAGGCAAAACAAACCGATCAAAATAGCGAAACTTGTTCTTTTCATTCGTTTTTTGTGTTTTTGTTATTCATAG
CGGAGCAAAAATAAGTATTT

Downstream 100 bases:

>100_bases
TAAGAAAGCAAAAAATAGAGACGCAGCATACACGCTACGTCTCTACACCCCACACCATATATCCATATTATATTACTTCA
ACAATTTTTCCTGAATCAAC

Product: anaerobic C4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSPIQTKSKELHSMLLQLAFVLIAIIIGARIGGIGLGVLGGLGLGILTFGFGLQPTSPPIDVMLMIVAVIAAASCMQAAG
GLDLMVKWAEKLLRKNPQRITILSPLVTYLFTFIAGTGHVAYSVLPVIAEVATETKIRPERPMAIAVIASQQAITASPIS
AATVALLSMLSGYNISLMNILMISVPCTLLGVLAGAIYSLKVGKELDQDPEYLKRVANHEFSTEHYEAKGVENQMKAALS
VSIFVLATIAIVIFGSMESLRPVFTVGTEKVSMQMSHIIEVLMLTASAFILLFTKTDGIKAAQGSVFSAGMQAVVAIFGI
AWMGDTFIAGNMTELKGSIEHIVTQMPWLFGLALFVMSILLFSQAATIRALLPLGIALGISPYMLIALFPAVNGYFFIPN
YPTVVAAINFDRTGTTRIGKYILNHSFMMPGLIATGVSVGLGLLFIQFI

Sequences:

>Translated_449_residues
MSPIQTKSKELHSMLLQLAFVLIAIIIGARIGGIGLGVLGGLGLGILTFGFGLQPTSPPIDVMLMIVAVIAAASCMQAAG
GLDLMVKWAEKLLRKNPQRITILSPLVTYLFTFIAGTGHVAYSVLPVIAEVATETKIRPERPMAIAVIASQQAITASPIS
AATVALLSMLSGYNISLMNILMISVPCTLLGVLAGAIYSLKVGKELDQDPEYLKRVANHEFSTEHYEAKGVENQMKAALS
VSIFVLATIAIVIFGSMESLRPVFTVGTEKVSMQMSHIIEVLMLTASAFILLFTKTDGIKAAQGSVFSAGMQAVVAIFGI
AWMGDTFIAGNMTELKGSIEHIVTQMPWLFGLALFVMSILLFSQAATIRALLPLGIALGISPYMLIALFPAVNGYFFIPN
YPTVVAAINFDRTGTTRIGKYILNHSFMMPGLIATGVSVGLGLLFIQFI
>Mature_448_residues
SPIQTKSKELHSMLLQLAFVLIAIIIGARIGGIGLGVLGGLGLGILTFGFGLQPTSPPIDVMLMIVAVIAAASCMQAAGG
LDLMVKWAEKLLRKNPQRITILSPLVTYLFTFIAGTGHVAYSVLPVIAEVATETKIRPERPMAIAVIASQQAITASPISA
ATVALLSMLSGYNISLMNILMISVPCTLLGVLAGAIYSLKVGKELDQDPEYLKRVANHEFSTEHYEAKGVENQMKAALSV
SIFVLATIAIVIFGSMESLRPVFTVGTEKVSMQMSHIIEVLMLTASAFILLFTKTDGIKAAQGSVFSAGMQAVVAIFGIA
WMGDTFIAGNMTELKGSIEHIVTQMPWLFGLALFVMSILLFSQAATIRALLPLGIALGISPYMLIALFPAVNGYFFIPNY
PTVVAAINFDRTGTTRIGKYILNHSFMMPGLIATGVSVGLGLLFIQFI

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790580, Length=437, Percent_Identity=42.79176201373, Blast_Score=322, Evalue=3e-89,
Organism=Escherichia coli, GI1790565, Length=406, Percent_Identity=41.6256157635468, Blast_Score=318, Evalue=4e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 47891; Mature: 47760

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPIQTKSKELHSMLLQLAFVLIAIIIGARIGGIGLGVLGGLGLGILTFGFGLQPTSPPI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHH
DVMLMIVAVIAAASCMQAAGGLDLMVKWAEKLLRKNPQRITILSPLVTYLFTFIAGTGHV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCHH
AYSVLPVIAEVATETKIRPERPMAIAVIASQQAITASPISAATVALLSMLSGYNISLMNI
HHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
LMISVPCTLLGVLAGAIYSLKVGKELDQDPEYLKRVANHEFSTEHYEAKGVENQMKAALS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHH
VSIFVLATIAIVIFGSMESLRPVFTVGTEKVSMQMSHIIEVLMLTASAFILLFTKTDGIK
HHHHHHHHHHHHHHCCHHHCCHHHEECHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCC
AAQGSVFSAGMQAVVAIFGIAWMGDTFIAGNMTELKGSIEHIVTQMPWLFGLALFVMSIL
CCCCHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFSQAATIRALLPLGIALGISPYMLIALFPAVNGYFFIPNYPTVVAAINFDRTGTTRIGK
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEECCCCCEEEEEEECCCCCHHHHHH
YILNHSFMMPGLIATGVSVGLGLLFIQFI
HHHHCCHHCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPIQTKSKELHSMLLQLAFVLIAIIIGARIGGIGLGVLGGLGLGILTFGFGLQPTSPPI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHH
DVMLMIVAVIAAASCMQAAGGLDLMVKWAEKLLRKNPQRITILSPLVTYLFTFIAGTGHV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCHH
AYSVLPVIAEVATETKIRPERPMAIAVIASQQAITASPISAATVALLSMLSGYNISLMNI
HHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
LMISVPCTLLGVLAGAIYSLKVGKELDQDPEYLKRVANHEFSTEHYEAKGVENQMKAALS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHH
VSIFVLATIAIVIFGSMESLRPVFTVGTEKVSMQMSHIIEVLMLTASAFILLFTKTDGIK
HHHHHHHHHHHHHHCCHHHCCHHHEECHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCC
AAQGSVFSAGMQAVVAIFGIAWMGDTFIAGNMTELKGSIEHIVTQMPWLFGLALFVMSIL
CCCCHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFSQAATIRALLPLGIALGISPYMLIALFPAVNGYFFIPNYPTVVAAINFDRTGTTRIGK
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEECCCCCEEEEEEECCCCCHHHHHH
YILNHSFMMPGLIATGVSVGLGLLFIQFI
HHHHCCHHCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]