Click here to switch to the map view.

The map label for this gene is yesM [H]

Identifier: 150008566

GI number: 150008566

Start: 2313668

End: 2314708

Strand: Reverse

Name: yesM [H]

Synonym: BDI_1952

Alternate gene names: 150008566

Gene position: 2314708-2313668 (Counterclockwise)

Preceding gene: 150008569

Following gene: 150008565

Centisome position: 48.11

GC content: 40.73

Gene sequence:

>1041_bases
ATGAAGATAAAATATAACTTTCTAAGTCCGTTGCTAATGGCGATATTGACGATCTGTTGCCTGTGGATTGTTACGGATGT
CGCTTATGGTGTCCGCATGTGGGAACTGGGAGTGGACGCGTGGATCGGGCGTATCAAGGCCCTTGCTATTATATTGATCG
GCGTTAGCTTATCTTATTTGTTTTTTAATTACTTGGCTAATACTTTTTTAGATAGGAATAAAGAGCGGAGGTCCCGCCCG
GTATTCCGGGAATATCTATGGGTGGTCTTGTTTAATTTAGTCGTGCTCAATATCGGCTTATATATCGTGATCTATTCTAT
AAATGGAACGACCTATCGGTGGGGAGAGGCGTTAATGATCAATGCGGTAGCTGTGCCGATCTTTCTCCTATACTATTTCT
TGATCCGTAATAATATATTAGCCAAACGCTATTCGGAGAAAATCGTTCAATTGGAGAAACTGAGAGTAGATCAGCTGGAA
ACGCAATTGAAGCTGCTGAAGATGCAATACCATCCCCATTTCCTGTTTAATGCCTTGAATACGATCTATTTCTTGATCGA
TGAGGAAAATGAGGAAGCGATTGAGGCTGTAGAGTTACTTTCGGACTTACTCCGTTATCAATTATATGATATAAATACGA
AAGTGACGATCGAAGAGGAGATTGATTATTTGCGAACATATATTCAATTCCAGCGACTTCGTATGACGAAACGCTTACAG
TTCGAGGAGTCCTTTGACCCGGAATTGACCGGACAAAAAATACATCCGTTGCTTTTCCAGCCATTATTGGAGAATGCGTT
TAAATATATAGGCGGAGCGTATCGGATACAAGTATCTATGCGGAAAGAGGGGGCAAAGGTCTGTTTGGGGGTAAGCAATA
CTTTCAATCCGGATTTCTTGGAACAAAGAAAGGGGAAAGGCATTGGGATCGACAATCTGAGAAAACGGTTGGAACTATTG
TACCCGGATAAACATGAGTTACGTATAAAAAAAGACAATACCCGTTTTAGGGTTGAGTTATGTATTGATTTATCAGAATA
A

Upstream 100 bases:

>100_bases
TTGGTTTTTATCTGGAACGATAACTTCGTTGATTAAAAAAGTACCTGTGATATGAGCATAGATCAAAGTAAAAGAATAAA
TTTATGGCTTGAAATCAGAT

Downstream 100 bases:

>100_bases
TATGGAAATAAAGTGTATCATAACGGATGATGAGCCAATCGCCAGAAAAGGACTTCGGCGACACATCGGTAAAATTGATT
TTCTGACCATCGTCGGAGAA

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKIKYNFLSPLLMAILTICCLWIVTDVAYGVRMWELGVDAWIGRIKALAIILIGVSLSYLFFNYLANTFLDRNKERRSRP
VFREYLWVVLFNLVVLNIGLYIVIYSINGTTYRWGEALMINAVAVPIFLLYYFLIRNNILAKRYSEKIVQLEKLRVDQLE
TQLKLLKMQYHPHFLFNALNTIYFLIDEENEEAIEAVELLSDLLRYQLYDINTKVTIEEEIDYLRTYIQFQRLRMTKRLQ
FEESFDPELTGQKIHPLLFQPLLENAFKYIGGAYRIQVSMRKEGAKVCLGVSNTFNPDFLEQRKGKGIGIDNLRKRLELL
YPDKHELRIKKDNTRFRVELCIDLSE

Sequences:

>Translated_346_residues
MKIKYNFLSPLLMAILTICCLWIVTDVAYGVRMWELGVDAWIGRIKALAIILIGVSLSYLFFNYLANTFLDRNKERRSRP
VFREYLWVVLFNLVVLNIGLYIVIYSINGTTYRWGEALMINAVAVPIFLLYYFLIRNNILAKRYSEKIVQLEKLRVDQLE
TQLKLLKMQYHPHFLFNALNTIYFLIDEENEEAIEAVELLSDLLRYQLYDINTKVTIEEEIDYLRTYIQFQRLRMTKRLQ
FEESFDPELTGQKIHPLLFQPLLENAFKYIGGAYRIQVSMRKEGAKVCLGVSNTFNPDFLEQRKGKGIGIDNLRKRLELL
YPDKHELRIKKDNTRFRVELCIDLSE
>Mature_346_residues
MKIKYNFLSPLLMAILTICCLWIVTDVAYGVRMWELGVDAWIGRIKALAIILIGVSLSYLFFNYLANTFLDRNKERRSRP
VFREYLWVVLFNLVVLNIGLYIVIYSINGTTYRWGEALMINAVAVPIFLLYYFLIRNNILAKRYSEKIVQLEKLRVDQLE
TQLKLLKMQYHPHFLFNALNTIYFLIDEENEEAIEAVELLSDLLRYQLYDINTKVTIEEEIDYLRTYIQFQRLRMTKRLQ
FEESFDPELTGQKIHPLLFQPLLENAFKYIGGAYRIQVSMRKEGAKVCLGVSNTFNPDFLEQRKGKGIGIDNLRKRLELL
YPDKHELRIKKDNTRFRVELCIDLSE

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=200, Percent_Identity=30, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788723, Length=198, Percent_Identity=30.8080808080808, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40944; Mature: 40944

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKYNFLSPLLMAILTICCLWIVTDVAYGVRMWELGVDAWIGRIKALAIILIGVSLSYL
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFNYLANTFLDRNKERRSRPVFREYLWVVLFNLVVLNIGLYIVIYSINGTTYRWGEALMI
HHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHCEEEEEEEECCCEEECCCHHHH
NAVAVPIFLLYYFLIRNNILAKRYSEKIVQLEKLRVDQLETQLKLLKMQYHPHFLFNALN
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TIYFLIDEENEEAIEAVELLSDLLRYQLYDINTKVTIEEEIDYLRTYIQFQRLRMTKRLQ
HEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHC
FEESFDPELTGQKIHPLLFQPLLENAFKYIGGAYRIQVSMRKEGAKVCLGVSNTFNPDFL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEECCCCCCHHHH
EQRKGKGIGIDNLRKRLELLYPDKHELRIKKDNTRFRVELCIDLSE
HHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEEEECC
>Mature Secondary Structure
MKIKYNFLSPLLMAILTICCLWIVTDVAYGVRMWELGVDAWIGRIKALAIILIGVSLSYL
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFNYLANTFLDRNKERRSRPVFREYLWVVLFNLVVLNIGLYIVIYSINGTTYRWGEALMI
HHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHCEEEEEEEECCCEEECCCHHHH
NAVAVPIFLLYYFLIRNNILAKRYSEKIVQLEKLRVDQLETQLKLLKMQYHPHFLFNALN
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TIYFLIDEENEEAIEAVELLSDLLRYQLYDINTKVTIEEEIDYLRTYIQFQRLRMTKRLQ
HEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHC
FEESFDPELTGQKIHPLLFQPLLENAFKYIGGAYRIQVSMRKEGAKVCLGVSNTFNPDFL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEECCCCCCHHHH
EQRKGKGIGIDNLRKRLELLYPDKHELRIKKDNTRFRVELCIDLSE
HHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]