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The map label for this gene is fba [H]

Identifier: 150008558

GI number: 150008558

Start: 2305226

End: 2306224

Strand: Reverse

Name: fba [H]

Synonym: BDI_1944

Alternate gene names: 150008558

Gene position: 2306224-2305226 (Counterclockwise)

Preceding gene: 150008561

Following gene: 150008556

Centisome position: 47.93

GC content: 45.35

Gene sequence:

>999_bases
ATGGTAAATTACAAAGATTTGGGCTTGGTGAACACAAAAGAAATGTTCGCTAAGGCTATCAAGGGCGGATATGCTATCCC
TGCTTTCAACTTCAATAACATGGAACAGATGCAGGCTATCATCAAGGCTGCTGTAGAGACAAAATCTCCGGTTATTTTGC
AAGTTTCAAAGGGCGCTCGCCAGTACGCAAACGCTACTTTGCTTCGTTACATGGCACAGGGTGCTGTTGAATATGCTAAG
GAATTAGGTTGCCCGAATCCTCAGATCGTTCTTCACTTAGACCATGGTGATACGTTTGAGACTTGCAAGAGCTGTATCGA
CTCTGGCTTCTCATCTGTAATGATCGACGGTTCTCACCTTCCTTATGAAGAGAACATCGCTTTGACTAAGAAAGTTGTTG
AGTACGCTCATCAATTCGATGTAACTGTAGAAGGCGAGCTTGGTGTATTGGCAGGTGTTGAGGATGAGGTTTCTTCAGAC
CACCACACTTATACCAATCCTGAGGAAGTTATCGACTTCGCTACTCGTACGGGCTGCGATTCTTTGGCTATCTCAATCGG
TACTTCTCACGGTGCTTATAAGTTCACTCCGGAGCAATGTACGATCGACCCTGTTACAGGTAAGATGGTTCCTCCTCCAT
TGGCATTCGACGTTTTGGACGCTGTTATGGAGAAACTTCCGGGATTCCCTATCGTTCTTCACGGTTCTTCTTCTGTTCCT
CAGGAAGAGGTTGAGACTATCAACAAATTCGGTGGCGCTTTGAAGGCTGCTATCGGTATTCCTGAAGAGTGGTTGCGTAA
GGCTGCTAAATCTTCTGTATGTAAGATCAATATCGACTCAGACTCTCGTTTGGCGATGACTGCCGCTATCCGCAAGACTT
TCGCTGAGAAACCGGCTGAATTCGATCCTCGTAAATATCTGGGCCCGGCTCGTGATAACATGGAGAAACTTTACAAACAC
AAGATCATCAACGTTCTTGGTTCTAACGACAAGTTATAA

Upstream 100 bases:

>100_bases
ATTTTGTGTTATTTTATATGCTTTGAAGCATCATTTGTCGTGAATCTTGATTATCTTTGTGCAAGTTTTTAATCATTAAC
GTAATAACATAATAACAACT

Downstream 100 bases:

>100_bases
TCGGAAGTTTCTTGATATAAATAAAGAAAGCCATCTCGGTATCGGGATGGCTTTTCTTTTGGTCTGTAGTTTAGTCTTTT
AATACCTTACGAAGCGCTTC

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MVNYKDLGLVNTKEMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAVETKSPVILQVSKGARQYANATLLRYMAQGAVEYAK
ELGCPNPQIVLHLDHGDTFETCKSCIDSGFSSVMIDGSHLPYEENIALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSD
HHTYTNPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCTIDPVTGKMVPPPLAFDVLDAVMEKLPGFPIVLHGSSSVP
QEEVETINKFGGALKAAIGIPEEWLRKAAKSSVCKINIDSDSRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKH
KIINVLGSNDKL

Sequences:

>Translated_332_residues
MVNYKDLGLVNTKEMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAVETKSPVILQVSKGARQYANATLLRYMAQGAVEYAK
ELGCPNPQIVLHLDHGDTFETCKSCIDSGFSSVMIDGSHLPYEENIALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSD
HHTYTNPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCTIDPVTGKMVPPPLAFDVLDAVMEKLPGFPIVLHGSSSVP
QEEVETINKFGGALKAAIGIPEEWLRKAAKSSVCKINIDSDSRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKH
KIINVLGSNDKL
>Mature_332_residues
MVNYKDLGLVNTKEMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAVETKSPVILQVSKGARQYANATLLRYMAQGAVEYAK
ELGCPNPQIVLHLDHGDTFETCKSCIDSGFSSVMIDGSHLPYEENIALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSD
HHTYTNPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCTIDPVTGKMVPPPLAFDVLDAVMEKLPGFPIVLHGSSSVP
QEEVETINKFGGALKAAIGIPEEWLRKAAKSSVCKINIDSDSRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKH
KIINVLGSNDKL

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI87082041, Length=312, Percent_Identity=34.6153846153846, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI1789526, Length=328, Percent_Identity=33.5365853658537, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1788072, Length=279, Percent_Identity=34.4086021505376, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1789293, Length=361, Percent_Identity=24.9307479224377, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 36290; Mature: 36290

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNYKDLGLVNTKEMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAVETKSPVILQVSKGAR
CCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHH
QYANATLLRYMAQGAVEYAKELGCPNPQIVLHLDHGDTFETCKSCIDSGFSSVMIDGSHL
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCC
PYEENIALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHTYTNPEEVIDFATRTGCD
CCCCCHHHHHHHHHHHHHCCCEECCCCCEEECCCHHHCCCCCCCCCHHHHHHHHHHCCCC
SLAISIGTSHGAYKFTPEQCTIDPVTGKMVPPPLAFDVLDAVMEKLPGFPIVLHGSSSVP
CEEEEEECCCCCEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
QEEVETINKFGGALKAAIGIPEEWLRKAAKSSVCKINIDSDSRLAMTAAIRKTFAEKPAE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCC
FDPRKYLGPARDNMEKLYKHKIINVLGSNDKL
CCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVNYKDLGLVNTKEMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAVETKSPVILQVSKGAR
CCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHH
QYANATLLRYMAQGAVEYAKELGCPNPQIVLHLDHGDTFETCKSCIDSGFSSVMIDGSHL
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCC
PYEENIALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHTYTNPEEVIDFATRTGCD
CCCCCHHHHHHHHHHHHHCCCEECCCCCEEECCCHHHCCCCCCCCCHHHHHHHHHHCCCC
SLAISIGTSHGAYKFTPEQCTIDPVTGKMVPPPLAFDVLDAVMEKLPGFPIVLHGSSSVP
CEEEEEECCCCCEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
QEEVETINKFGGALKAAIGIPEEWLRKAAKSSVCKINIDSDSRLAMTAAIRKTFAEKPAE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCC
FDPRKYLGPARDNMEKLYKHKIINVLGSNDKL
CCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]