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The map label for this gene is tcrA [H]

Identifier: 150008544

GI number: 150008544

Start: 2288970

End: 2289650

Strand: Direct

Name: tcrA [H]

Synonym: BDI_1930

Alternate gene names: 150008544

Gene position: 2288970-2289650 (Clockwise)

Preceding gene: 150008543

Following gene: 150008545

Centisome position: 47.57

GC content: 43.32

Gene sequence:

>681_bases
ATGAAAATTCTGGTAGTCGAAGATGAAAACGCACTGAGAGAAGTTATCGTTCGTTCTCTTGAAAAAGAACGATATGTGGT
AGAGAGCGCTTCCTCTTTCCGGGAAGCTTCTCTTAAAATAAATGATTATGATTACGATTGTATCGTATTGGACATCATGC
TTCCGGGAGGTAGCGGCCTTACCCTTTTGAAGGAATTAAGGGCCTTACGCAAGAAAGACAGTATCATCATTATCTCCGCA
AAAGACTCTATCGAGGATAAAGTTACAGGATTAGATCTTGGGGCCGATGATTATCTGACCAAGCCTTTCCATCTGGCGGA
ATTGAACGCCCGCATCAAGAGCGTTATCCGCCGCAAGCAACAAGATGGGGAATTGCAACTGTCTTTAGCGAACCTAACGA
TATATCCCGATAAACATTCCGTCTATATAAACGGGAAAGAGATCGTATTGAACCGTAAGGAGTTCGATCTGCTCTACTAT
TTCATATCCAACCCCAACCGTTTGATCAGCAAAGCTACTTTAGCCGAGTCCGTCTGGGGAGATTATATAGACCAAGCCGA
TAATTTCGACTTCATCTATAGCCAAGTAAAAAACTTGCGAAAGAAATTAAAAGCCGCCGGAGCCATCCCCGAAATAAAGG
CGGTCTATGGCTTCGGTTACAAAATGACCGACGAGGAATAA

Upstream 100 bases:

>100_bases
CAGAGGCCCAATTATTGAAGTAGAACGATACTGAATCTTTTCTTATTCCAGATTTTTATCAGAATATTTCAGTAGCTTTG
TGTGATTAACAAGCTAGCCT

Downstream 100 bases:

>100_bases
ATATGAAGCTAATCCATTACACCCTCCGCAATTTATTTGTCCCCATATTGGTCATTTTCGCCGCTTGGGGATGTGTTTTC
TGCCTTATGATTCTACATGA

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKILVVEDENALREVIVRSLEKERYVVESASSFREASLKINDYDYDCIVLDIMLPGGSGLTLLKELRALRKKDSIIIISA
KDSIEDKVTGLDLGADDYLTKPFHLAELNARIKSVIRRKQQDGELQLSLANLTIYPDKHSVYINGKEIVLNRKEFDLLYY
FISNPNRLISKATLAESVWGDYIDQADNFDFIYSQVKNLRKKLKAAGAIPEIKAVYGFGYKMTDEE

Sequences:

>Translated_226_residues
MKILVVEDENALREVIVRSLEKERYVVESASSFREASLKINDYDYDCIVLDIMLPGGSGLTLLKELRALRKKDSIIIISA
KDSIEDKVTGLDLGADDYLTKPFHLAELNARIKSVIRRKQQDGELQLSLANLTIYPDKHSVYINGKEIVLNRKEFDLLYY
FISNPNRLISKATLAESVWGDYIDQADNFDFIYSQVKNLRKKLKAAGAIPEIKAVYGFGYKMTDEE
>Mature_226_residues
MKILVVEDENALREVIVRSLEKERYVVESASSFREASLKINDYDYDCIVLDIMLPGGSGLTLLKELRALRKKDSIIIISA
KDSIEDKVTGLDLGADDYLTKPFHLAELNARIKSVIRRKQQDGELQLSLANLTIYPDKHSVYINGKEIVLNRKEFDLLYY
FISNPNRLISKATLAESVWGDYIDQADNFDFIYSQVKNLRKKLKAAGAIPEIKAVYGFGYKMTDEE

Specific function: Member of the three-protein two-component system HK1/HK2/tcrA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=34.6666666666667, Blast_Score=140, Evalue=5e-35,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=33.6283185840708, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=35.8744394618834, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=35.8744394618834, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=30.6666666666667, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=35.7142857142857, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=29.4372294372294, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=31.140350877193, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=30.316742081448, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=30.0448430493274, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=29.1479820627803, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=32.1739130434783, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=28.7610619469027, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788550, Length=125, Percent_Identity=28.8, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25763; Mature: 25763

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVVEDENALREVIVRSLEKERYVVESASSFREASLKINDYDYDCIVLDIMLPGGSGL
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEEEEECCCCCH
TLLKELRALRKKDSIIIISAKDSIEDKVTGLDLGADDYLTKPFHLAELNARIKSVIRRKQ
HHHHHHHHHHCCCCEEEEECCCCCCHHHCEECCCCCCCCCCCCHHHHHHHHHHHHHHHCC
QDGELQLSLANLTIYPDKHSVYINGKEIVLNRKEFDLLYYFISNPNRLISKATLAESVWG
CCCCEEEEEEEEEEECCCCEEEECCCEEEEECCCEEEEEEEECCCHHHHHHHHHHHHHHH
DYIDQADNFDFIYSQVKNLRKKLKAAGAIPEIKAVYGFGYKMTDEE
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHEECCEEECCCC
>Mature Secondary Structure
MKILVVEDENALREVIVRSLEKERYVVESASSFREASLKINDYDYDCIVLDIMLPGGSGL
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEEEEECCCCCH
TLLKELRALRKKDSIIIISAKDSIEDKVTGLDLGADDYLTKPFHLAELNARIKSVIRRKQ
HHHHHHHHHHCCCCEEEEECCCCCCHHHCEECCCCCCCCCCCCHHHHHHHHHHHHHHHCC
QDGELQLSLANLTIYPDKHSVYINGKEIVLNRKEFDLLYYFISNPNRLISKATLAESVWG
CCCCEEEEEEEEEEECCCCEEEECCCEEEEECCCEEEEEEEECCCHHHHHHHHHHHHHHH
DYIDQADNFDFIYSQVKNLRKKLKAAGAIPEIKAVYGFGYKMTDEE
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHEECCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]