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The map label for this gene is fabD [H]

Identifier: 150008386

GI number: 150008386

Start: 2088487

End: 2089368

Strand: Direct

Name: fabD [H]

Synonym: BDI_1760

Alternate gene names: 150008386

Gene position: 2088487-2089368 (Clockwise)

Preceding gene: 150008383

Following gene: 150008387

Centisome position: 43.41

GC content: 49.55

Gene sequence:

>882_bases
ATGAAAGCGTACGTATTTCCCGGTCAGGGGGCACAGTTCGTAGGTATGGGCAAAGACCTCTACGATAATAATCCTCTTGC
TAAAGAGATGTTTGAGAAGGCTAACGAGATCCTTGGTTTCCGTATCACGGATTTAATGTTTGCCGGAACAGACGAGGATC
TGAGACAAACCAAAGTTACTCAACCAGCGATCTTCTTACACTCTGTCATTCTCGCGAAAACATTAGGTGATCAATTCCAA
CCGGATATGACCGCAGGTCACTCATTAGGAGAATTCTCTGCCTTGGTAGCTGCCGGAGCATTGTCTTTCGAGGACGGCTT
GGTATTAGTTTCCAAACGTGCCATGGCTATGCAAAAGGCTTGCGAGGCAACTCCCTCTACAATGGCCGCCGTATTAGCCT
TGCCGGACGCGACGGTTGAGGAAATTTGCGCGAGCATCAAGGACGAGGTAGTGGTTTGCGCTAACTATAATTGCCCGGGC
CAATTGGTAATCTCCGGCTCTATCCCCGGTATCGATCAGGCTTGCGAGAAGTTATTGGCCGCAGGCGCTAAGCGTGCCTT
GAAGTTGAAAGTAGGTGGAGCGTTCCATTCTCCATTGATGGAACCAGCTCGTACTGAGTTGGCTGCCGCTATCGAGGCTA
CGACGATCAATAAACCTTCTTGCCCGGTTTACCAGAACGTAAGCACGAAAGCCGAGACTTGCCCGGAAACAATTAAGACT
AACTTGATCGCACAGTTAACCGCCCCGGTACGTTGGACCCAAAGCGTACAGAACATGATCGCCGACGGTGCCACTCATTT
CATCGAGTTAGGCCCGGGTGCCGTTCTTCAGGGATTGGTTAAAAAGATCAATAAGGAAATGACTACGGAAGGTATGCAAT
AA

Upstream 100 bases:

>100_bases
GGGGCAAAGATACAATTTGTAATGAATAGTAGCCTCATTATTCCAAATTTATTACCTTTGCACCGTCTTAAAAAACTGAA
ATTAGAAAAAAATTAGAAAG

Downstream 100 bases:

>100_bases
TTTACCTTTCAATGTAATAGGATAAAAGTCCGAAAAGGATGGAGGGTGATTTTCCTCGTCTTTTCCGGACTTTTTTATAT
ACGATGATGATTCGAAAAGA

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MKAYVFPGQGAQFVGMGKDLYDNNPLAKEMFEKANEILGFRITDLMFAGTDEDLRQTKVTQPAIFLHSVILAKTLGDQFQ
PDMTAGHSLGEFSALVAAGALSFEDGLVLVSKRAMAMQKACEATPSTMAAVLALPDATVEEICASIKDEVVVCANYNCPG
QLVISGSIPGIDQACEKLLAAGAKRALKLKVGGAFHSPLMEPARTELAAAIEATTINKPSCPVYQNVSTKAETCPETIKT
NLIAQLTAPVRWTQSVQNMIADGATHFIELGPGAVLQGLVKKINKEMTTEGMQ

Sequences:

>Translated_293_residues
MKAYVFPGQGAQFVGMGKDLYDNNPLAKEMFEKANEILGFRITDLMFAGTDEDLRQTKVTQPAIFLHSVILAKTLGDQFQ
PDMTAGHSLGEFSALVAAGALSFEDGLVLVSKRAMAMQKACEATPSTMAAVLALPDATVEEICASIKDEVVVCANYNCPG
QLVISGSIPGIDQACEKLLAAGAKRALKLKVGGAFHSPLMEPARTELAAAIEATTINKPSCPVYQNVSTKAETCPETIKT
NLIAQLTAPVRWTQSVQNMIADGATHFIELGPGAVLQGLVKKINKEMTTEGMQ
>Mature_293_residues
MKAYVFPGQGAQFVGMGKDLYDNNPLAKEMFEKANEILGFRITDLMFAGTDEDLRQTKVTQPAIFLHSVILAKTLGDQFQ
PDMTAGHSLGEFSALVAAGALSFEDGLVLVSKRAMAMQKACEATPSTMAAVLALPDATVEEICASIKDEVVVCANYNCPG
QLVISGSIPGIDQACEKLLAAGAKRALKLKVGGAFHSPLMEPARTELAAAIEATTINKPSCPVYQNVSTKAETCPETIKT
NLIAQLTAPVRWTQSVQNMIADGATHFIELGPGAVLQGLVKKINKEMTTEGMQ

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=299, Percent_Identity=37.7926421404682, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI27477045, Length=108, Percent_Identity=41.6666666666667, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1787334, Length=293, Percent_Identity=42.320819112628, Blast_Score=203, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71984332, Length=296, Percent_Identity=32.4324324324324, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17550940, Length=288, Percent_Identity=28.4722222222222, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24665753, Length=300, Percent_Identity=34.6666666666667, Blast_Score=152, Evalue=3e-37,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31178; Mature: 31178

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAYVFPGQGAQFVGMGKDLYDNNPLAKEMFEKANEILGFRITDLMFAGTDEDLRQTKVT
CCEEEECCCCCEEEECCCHHCCCCCHHHHHHHHHHHHHCEEHHHHEECCCCHHHHHHHCC
QPAIFLHSVILAKTLGDQFQPDMTAGHSLGEFSALVAAGALSFEDGLVLVSKRAMAMQKA
CHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHH
CEATPSTMAAVLALPDATVEEICASIKDEVVVCANYNCPGQLVISGSIPGIDQACEKLLA
HCCCHHHHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHH
AGAKRALKLKVGGAFHSPLMEPARTELAAAIEATTINKPSCPVYQNVSTKAETCPETIKT
HCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCHHHHHH
NLIAQLTAPVRWTQSVQNMIADGATHFIELGPGAVLQGLVKKINKEMTTEGMQ
HHHHHHHCCHHHHHHHHHHHHCCCHHEEECCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKAYVFPGQGAQFVGMGKDLYDNNPLAKEMFEKANEILGFRITDLMFAGTDEDLRQTKVT
CCEEEECCCCCEEEECCCHHCCCCCHHHHHHHHHHHHHCEEHHHHEECCCCHHHHHHHCC
QPAIFLHSVILAKTLGDQFQPDMTAGHSLGEFSALVAAGALSFEDGLVLVSKRAMAMQKA
CHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHH
CEATPSTMAAVLALPDATVEEICASIKDEVVVCANYNCPGQLVISGSIPGIDQACEKLLA
HCCCHHHHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHH
AGAKRALKLKVGGAFHSPLMEPARTELAAAIEATTINKPSCPVYQNVSTKAETCPETIKT
HCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCHHHHHH
NLIAQLTAPVRWTQSVQNMIADGATHFIELGPGAVLQGLVKKINKEMTTEGMQ
HHHHHHHCCHHHHHHHHHHHHCCCHHEEECCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]