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The map label for this gene is rcsC [H]

Identifier: 150008357

GI number: 150008357

Start: 2049297

End: 2050550

Strand: Reverse

Name: rcsC [H]

Synonym: BDI_1731

Alternate gene names: 150008357

Gene position: 2050550-2049297 (Counterclockwise)

Preceding gene: 150008358

Following gene: 150008356

Centisome position: 42.62

GC content: 45.93

Gene sequence:

>1254_bases
ATGAAACACCTACTTTATATATTTTTAGTTTTAGCAACCTTGCTTACGGGGTTGTACTTGCTACCTAAGCATACTCCCTT
ATTTGAGTATTATAGGCTGAGGCCTGTTTTTGAGGTAGCTACTATCGTATTTTTAATCGGTGTCTTATGCTTGTATGGGC
GGGAGAAGAGGCAAGTCAAGATGATCTTCTCCCGTCTGTCTCAAAAGAATTTCTTCTTGGATTTGGCCATACAGTGTGGA
GGCATATACATCTGGGAGTTTAAGGACGAGGAGTTCTTTTTCGAGTATCCTGTCGGTGACCAGTCATCACGGATCGAGTT
GGAAGAGATGTGGAGGCTGATACATCCCGATGATCTCACTGCTTTCAAATTACTTTGGCAATCCTTATGGAAGGCGGACA
AGGAGGTATTCCAATGCCGTGCCCGCTTCGCCGGATCTGATTATGAATGGTGGGAATTCCGCTTTAGCGCCATGCCTGCG
GTAGATAATGCGGAGGGAGGCAAAGACGTGAGCGGTATACTTATCAATATCAATGACATGAAGAAACGAGAAAAAGAGCT
TATCCTCATGAGGGGATATGAGCAAAAGTTCTTGGCGAACATGAGCCATGAGATACGTACGCCGCTGAACTCTATCGTAG
GCTTCTCGAACCTGCTGGCCTCGGAGAAGGACTTAGACGAGGCCGACAAGCAGCTGTTTGCCAAGACGATCAATCAGAGT
TGCGATCTGTTGTTGGTGCTCATCAATGATATTTTGGAGGTTTCGAGACTTCAATCGGGACAAATGAAATTCGAGAAAGA
GAGCTGCTCCGTCAAGGAGTTGGTAGACGACCTTTACCTCGCCCATCAGTTATTAGTCCCCACCCACCTACAATTCTCGA
AAGAGGCGGAGGGGGATTTGTTTATCTATACGGATAAAAAGAGACTTTCTCAAGTTATAACCAATTTCTTGACAAACGCT
TGTAAATTCACGAATAGCGGATATATAAAGTTGGGATTTAAGCATCTGAGGGGGACGGATGAGGTAGCGATTTTTGTCAA
GGATTCCGGGATCGGTCTATCGGAGGAGCAACAAGAGAAGGTGTTCAGCCGTTTTTTCAAGCAAGATGAATTCAGCCAAG
GGGCCGGTCTGGGGTTGTCTATCTGCCAAGGAATCGTACAAAACTTGGGGGGACGGATAGAACTGAGTTCTAAGCTAGGA
AAAGGAAGCCGCTTCTCGGTTGTGCTGCCGGTATATAAGGGGGGATACGTTTGA

Upstream 100 bases:

>100_bases
AATAATAGTCTTAAGAAAAAAAACAATAGTGTTAATGAGCGGAGTGAAATAAAACCATTTACCACCAGAGTCCCGCAGGT
ACTCGTAAACTTAAAGAACC

Downstream 100 bases:

>100_bases
TCATTCGTTTTTTTCATTCTACCAAAATCTGATATCTGATGGGAAAGAAGTACATTTGCCGGATCAAAATAGAAGAAGAT
AAATGGCATTGAAACTTATC

Product: putative two-component regulator sensor kinase

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MKHLLYIFLVLATLLTGLYLLPKHTPLFEYYRLRPVFEVATIVFLIGVLCLYGREKRQVKMIFSRLSQKNFFLDLAIQCG
GIYIWEFKDEEFFFEYPVGDQSSRIELEEMWRLIHPDDLTAFKLLWQSLWKADKEVFQCRARFAGSDYEWWEFRFSAMPA
VDNAEGGKDVSGILININDMKKREKELILMRGYEQKFLANMSHEIRTPLNSIVGFSNLLASEKDLDEADKQLFAKTINQS
CDLLLVLINDILEVSRLQSGQMKFEKESCSVKELVDDLYLAHQLLVPTHLQFSKEAEGDLFIYTDKKRLSQVITNFLTNA
CKFTNSGYIKLGFKHLRGTDEVAIFVKDSGIGLSEEQQEKVFSRFFKQDEFSQGAGLGLSICQGIVQNLGGRIELSSKLG
KGSRFSVVLPVYKGGYV

Sequences:

>Translated_417_residues
MKHLLYIFLVLATLLTGLYLLPKHTPLFEYYRLRPVFEVATIVFLIGVLCLYGREKRQVKMIFSRLSQKNFFLDLAIQCG
GIYIWEFKDEEFFFEYPVGDQSSRIELEEMWRLIHPDDLTAFKLLWQSLWKADKEVFQCRARFAGSDYEWWEFRFSAMPA
VDNAEGGKDVSGILININDMKKREKELILMRGYEQKFLANMSHEIRTPLNSIVGFSNLLASEKDLDEADKQLFAKTINQS
CDLLLVLINDILEVSRLQSGQMKFEKESCSVKELVDDLYLAHQLLVPTHLQFSKEAEGDLFIYTDKKRLSQVITNFLTNA
CKFTNSGYIKLGFKHLRGTDEVAIFVKDSGIGLSEEQQEKVFSRFFKQDEFSQGAGLGLSICQGIVQNLGGRIELSSKLG
KGSRFSVVLPVYKGGYV
>Mature_417_residues
MKHLLYIFLVLATLLTGLYLLPKHTPLFEYYRLRPVFEVATIVFLIGVLCLYGREKRQVKMIFSRLSQKNFFLDLAIQCG
GIYIWEFKDEEFFFEYPVGDQSSRIELEEMWRLIHPDDLTAFKLLWQSLWKADKEVFQCRARFAGSDYEWWEFRFSAMPA
VDNAEGGKDVSGILININDMKKREKELILMRGYEQKFLANMSHEIRTPLNSIVGFSNLLASEKDLDEADKQLFAKTINQS
CDLLLVLINDILEVSRLQSGQMKFEKESCSVKELVDDLYLAHQLLVPTHLQFSKEAEGDLFIYTDKKRLSQVITNFLTNA
CKFTNSGYIKLGFKHLRGTDEVAIFVKDSGIGLSEEQQEKVFSRFFKQDEFSQGAGLGLSICQGIVQNLGGRIELSSKLG
KGSRFSVVLPVYKGGYV

Specific function: Member of the two-component regulatory system RcsC/RcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with RcsF, RcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=260, Percent_Identity=35.3846153846154, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788713, Length=269, Percent_Identity=32.3420074349442, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789149, Length=240, Percent_Identity=35, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI48994928, Length=296, Percent_Identity=27.027027027027, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87081816, Length=223, Percent_Identity=32.7354260089686, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=26.5486725663717, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786912, Length=219, Percent_Identity=30.1369863013699, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=29.535864978903, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1788549, Length=263, Percent_Identity=26.9961977186312, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788393, Length=226, Percent_Identity=27.8761061946903, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790346, Length=235, Percent_Identity=28.936170212766, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1787894, Length=243, Percent_Identity=24.6913580246914, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786783, Length=230, Percent_Identity=23.9130434782609, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=255, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=27.3127753303965, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47969; Mature: 47969

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHLLYIFLVLATLLTGLYLLPKHTPLFEYYRLRPVFEVATIVFLIGVLCLYGREKRQVK
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
MIFSRLSQKNFFLDLAIQCGGIYIWEFKDEEFFFEYPVGDQSSRIELEEMWRLIHPDDLT
HHHHHHCCCCEEEEEEEEECCEEEEEECCCCEEEECCCCCCCCCEEHHHHHHHCCCCCHH
AFKLLWQSLWKADKEVFQCRARFAGSDYEWWEFRFSAMPAVDNAEGGKDVSGILININDM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEECCCCCCCCCCCCCCEEEEEEEHHH
KKREKELILMRGYEQKFLANMSHEIRTPLNSIVGFSNLLASEKDLDEADKQLFAKTINQS
HHHHHHEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCC
CDLLLVLINDILEVSRLQSGQMKFEKESCSVKELVDDLYLAHQLLVPTHLQFSKEAEGDL
HHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCE
FIYTDKKRLSQVITNFLTNACKFTNSGYIKLGFKHLRGTDEVAIFVKDSGIGLSEEQQEK
EEEECHHHHHHHHHHHHHHHHHCCCCCEEEECHHHCCCCCCEEEEEECCCCCCCHHHHHH
VFSRFFKQDEFSQGAGLGLSICQGIVQNLGGRIELSSKLGKGSRFSVVLPVYKGGYV
HHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKHLLYIFLVLATLLTGLYLLPKHTPLFEYYRLRPVFEVATIVFLIGVLCLYGREKRQVK
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
MIFSRLSQKNFFLDLAIQCGGIYIWEFKDEEFFFEYPVGDQSSRIELEEMWRLIHPDDLT
HHHHHHCCCCEEEEEEEEECCEEEEEECCCCEEEECCCCCCCCCEEHHHHHHHCCCCCHH
AFKLLWQSLWKADKEVFQCRARFAGSDYEWWEFRFSAMPAVDNAEGGKDVSGILININDM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEECCCCCCCCCCCCCCEEEEEEEHHH
KKREKELILMRGYEQKFLANMSHEIRTPLNSIVGFSNLLASEKDLDEADKQLFAKTINQS
HHHHHHEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCC
CDLLLVLINDILEVSRLQSGQMKFEKESCSVKELVDDLYLAHQLLVPTHLQFSKEAEGDL
HHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCE
FIYTDKKRLSQVITNFLTNACKFTNSGYIKLGFKHLRGTDEVAIFVKDSGIGLSEEQQEK
EEEECHHHHHHHHHHHHHHHHHCCCCCEEEECHHHCCCCCCEEEEEECCCCCCCHHHHHH
VFSRFFKQDEFSQGAGLGLSICQGIVQNLGGRIELSSKLGKGSRFSVVLPVYKGGYV
HHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2404948; 8366025; 9097040; 9278503; 11758943; 11309126; 13129944 [H]