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The map label for this gene is mepA [H]

Identifier: 150008342

GI number: 150008342

Start: 2030419

End: 2031768

Strand: Direct

Name: mepA [H]

Synonym: BDI_1716

Alternate gene names: 150008342

Gene position: 2030419-2031768 (Clockwise)

Preceding gene: 150008337

Following gene: 150008343

Centisome position: 42.2

GC content: 43.41

Gene sequence:

>1350_bases
ATGATGCAAGACAGTATTGATTTTGGAACAATGAACATTCCGAAGTTGTTCCGTATGATGTTTATCCCTACCTTATTAGG
TATGATCCTTTCCGCCACTATTAATATCGCCGATGGAATATTCGTAGGAAGAGGCGTAGGAAATGACGCCTTGGCTGCGG
TAAATATCGTGGCTCCTTTTTTCATGTTAGCAACCGGAATCGGGCTTATGTTCGGAGTAGGCGCTTCTATCGTCGCCTCG
ATCCACCTTTCACACCAGAAAGTCAAGGTAGCGAATATTAATATCACGCAAGCGCTTTCGATCTCATTATGTATTATGTT
ATCGCTTTCCTTGTTAGTGATGACATTCCGTGCTGAGGTCGCTCTTTTATTGGGTAGTTCCGAGCAATTATTGCCCTCCG
TATTGGAATATATGAACTGGATCGTCCCGTTCCTTGCCTTTTACATGTTATTGAATATCGGGTTATTCATTATCCGGTTA
GACGGATCACCTACATACGCCATGTTATGCAGCGCTATCCCGGCCCTGATAAACCTAACATTAGACTATATTTTCGTTTT
CCCATTGCATTGGGGATTAATGGGAGCCGCTTTAGCTTCCGCTATTTCCGTAATCGTAGGAAGTATTATGATCGTGGTTT
ATATCGTAGGTTTTTCTAAAGTATTACATCTTTACCGCCCTAAATTCTCGCTTAAAAGTATCTTATTGACAATCCGCAAT
ATCGGATACATGGTAAAGCTTGGTTCTTCCGCGTTCTTAACTGAGGCAGCTATCGCTTGTATGATGCTGGTGGGTAATTA
TATATTCATGAGATACCTTGGGGAAGACGGGGTTGCCGCCTACAGTGTAGCCTGTTATTGCTTTCCTATCGTATTCATGG
TGAACAATGCGATCGCCCAGTCTACCCAGCCGATCATAAGCTACAACTATGGCATACAGCAGTGGAAAAGAGTACGGCAG
GCGTTTAAGTTAGCCCTGCTATGCGCTGTCGTGTGCGGAGGACTCGCCTGCGTGGGTACTATTTTATTCTGCCCGGAAGT
CTCCTCCTTATTTCTCGGTAATCATGGCAACGCTTACGAGATAGCGGTCTCCGGCATTCCCTATTTTTCTTTGGGATATG
TCTTTTTCGCTCTCAATATCGTTTGTATCGGGTACTACCAGAGCATAGAACGTTTCAAACCCGCTACGCTATTCACTATT
CTACGAGGAATCGTGATTATCACCCTAAGTTTCATGTACCTACCTGTTGTCTGCGGAATTAAAGGTATTTGGCTGGCCGT
ACCTTTGTCGGAATTAATTACTTTTGTAATCATTGTGGTATACTATCTATTGAAACGTACAAGAGCATGA

Upstream 100 bases:

>100_bases
TTCAAACTTGATAAATACTCCGTTTTTTACCCTAATGGTAACTTTTTTCTAAATGGAGAAGCCTACTTTTGTGCCGCAAA
AATAAAAAGAAAAGAAACTG

Downstream 100 bases:

>100_bases
AAGAGGAAGTTCGCCAGAAAGTGATGGAACGGTTTTCAATCTCTGAGCAGGCCATGCGGTTATTGCTGGAAAGCGCAGAG
ATGATGTCGTTTGTCCCCAA

Product: putative transmembrane cation efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MMQDSIDFGTMNIPKLFRMMFIPTLLGMILSATINIADGIFVGRGVGNDALAAVNIVAPFFMLATGIGLMFGVGASIVAS
IHLSHQKVKVANINITQALSISLCIMLSLSLLVMTFRAEVALLLGSSEQLLPSVLEYMNWIVPFLAFYMLLNIGLFIIRL
DGSPTYAMLCSAIPALINLTLDYIFVFPLHWGLMGAALASAISVIVGSIMIVVYIVGFSKVLHLYRPKFSLKSILLTIRN
IGYMVKLGSSAFLTEAAIACMMLVGNYIFMRYLGEDGVAAYSVACYCFPIVFMVNNAIAQSTQPIISYNYGIQQWKRVRQ
AFKLALLCAVVCGGLACVGTILFCPEVSSLFLGNHGNAYEIAVSGIPYFSLGYVFFALNIVCIGYYQSIERFKPATLFTI
LRGIVIITLSFMYLPVVCGIKGIWLAVPLSELITFVIIVVYYLLKRTRA

Sequences:

>Translated_449_residues
MMQDSIDFGTMNIPKLFRMMFIPTLLGMILSATINIADGIFVGRGVGNDALAAVNIVAPFFMLATGIGLMFGVGASIVAS
IHLSHQKVKVANINITQALSISLCIMLSLSLLVMTFRAEVALLLGSSEQLLPSVLEYMNWIVPFLAFYMLLNIGLFIIRL
DGSPTYAMLCSAIPALINLTLDYIFVFPLHWGLMGAALASAISVIVGSIMIVVYIVGFSKVLHLYRPKFSLKSILLTIRN
IGYMVKLGSSAFLTEAAIACMMLVGNYIFMRYLGEDGVAAYSVACYCFPIVFMVNNAIAQSTQPIISYNYGIQQWKRVRQ
AFKLALLCAVVCGGLACVGTILFCPEVSSLFLGNHGNAYEIAVSGIPYFSLGYVFFALNIVCIGYYQSIERFKPATLFTI
LRGIVIITLSFMYLPVVCGIKGIWLAVPLSELITFVIIVVYYLLKRTRA
>Mature_449_residues
MMQDSIDFGTMNIPKLFRMMFIPTLLGMILSATINIADGIFVGRGVGNDALAAVNIVAPFFMLATGIGLMFGVGASIVAS
IHLSHQKVKVANINITQALSISLCIMLSLSLLVMTFRAEVALLLGSSEQLLPSVLEYMNWIVPFLAFYMLLNIGLFIIRL
DGSPTYAMLCSAIPALINLTLDYIFVFPLHWGLMGAALASAISVIVGSIMIVVYIVGFSKVLHLYRPKFSLKSILLTIRN
IGYMVKLGSSAFLTEAAIACMMLVGNYIFMRYLGEDGVAAYSVACYCFPIVFMVNNAIAQSTQPIISYNYGIQQWKRVRQ
AFKLALLCAVVCGGLACVGTILFCPEVSSLFLGNHGNAYEIAVSGIPYFSLGYVFFALNIVCIGYYQSIERFKPATLFTI
LRGIVIITLSFMYLPVVCGIKGIWLAVPLSELITFVIIVVYYLLKRTRA

Specific function: Multidrug resistance efflux protein [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49159; Mature: 49159

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQDSIDFGTMNIPKLFRMMFIPTLLGMILSATINIADGIFVGRGVGNDALAAVNIVAPF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHH
FMLATGIGLMFGVGASIVASIHLSHQKVKVANINITQALSISLCIMLSLSLLVMTFRAEV
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLLGSSEQLLPSVLEYMNWIVPFLAFYMLLNIGLFIIRLDGSPTYAMLCSAIPALINLT
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHH
LDYIFVFPLHWGLMGAALASAISVIVGSIMIVVYIVGFSKVLHLYRPKFSLKSILLTIRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IGYMVKLGSSAFLTEAAIACMMLVGNYIFMRYLGEDGVAAYSVACYCFPIVFMVNNAIAQ
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
STQPIISYNYGIQQWKRVRQAFKLALLCAVVCGGLACVGTILFCPEVSSLFLGNHGNAYE
CCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHCCCCCCEEE
IAVSGIPYFSLGYVFFALNIVCIGYYQSIERFKPATLFTILRGIVIITLSFMYLPVVCGI
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
KGIWLAVPLSELITFVIIVVYYLLKRTRA
CHHHHHCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMQDSIDFGTMNIPKLFRMMFIPTLLGMILSATINIADGIFVGRGVGNDALAAVNIVAPF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHH
FMLATGIGLMFGVGASIVASIHLSHQKVKVANINITQALSISLCIMLSLSLLVMTFRAEV
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLLGSSEQLLPSVLEYMNWIVPFLAFYMLLNIGLFIIRLDGSPTYAMLCSAIPALINLT
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHH
LDYIFVFPLHWGLMGAALASAISVIVGSIMIVVYIVGFSKVLHLYRPKFSLKSILLTIRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IGYMVKLGSSAFLTEAAIACMMLVGNYIFMRYLGEDGVAAYSVACYCFPIVFMVNNAIAQ
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
STQPIISYNYGIQQWKRVRQAFKLALLCAVVCGGLACVGTILFCPEVSSLFLGNHGNAYE
CCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHCCCCCCEEE
IAVSGIPYFSLGYVFFALNIVCIGYYQSIERFKPATLFTILRGIVIITLSFMYLPVVCGI
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
KGIWLAVPLSELITFVIIVVYYLLKRTRA
CHHHHHCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA