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The map label for this gene is tkt [H]

Identifier: 150008299

GI number: 150008299

Start: 1971560

End: 1973590

Strand: Direct

Name: tkt [H]

Synonym: BDI_1668

Alternate gene names: 150008299

Gene position: 1971560-1973590 (Clockwise)

Preceding gene: 150008298

Following gene: 150008300

Centisome position: 40.98

GC content: 49.04

Gene sequence:

>2031_bases
ATGAACGATATTCAAGTAATGAACAAAGCAGCTGATAACATCCGTATACTGGCTGCGTCAATGGTGGAGAAAGCGAACTC
CGGGCACCCGGGTGGCGCTATGGGTGGTGCAGACTTTGTTAACGTACTGTTCTCAGAGTTCTTAATATACGATCCCAAGA
ATCCCAAATGGGAAGGACGCGATCGTTTCTTCCTTGACCCGGGGCATATGTCTCCGATGCTTTATTCCGTACTGGCTTTA
AGCGGCAAATTCACATTGGATGAACTTCAACAGTTCCGCCAATGGGGAAGCGTTACTCCGGGACATCCTGAGGTAGACGT
TATGCGTGGTATCGAAAACACGTCCGGCCCGCTGGGACAAGGACATACTTATGCGGTAGGTGCGGCTATCGCGGCTAAAT
TCTTGAAAGCACGTCTGGGTGAGGAAGTAATGAACCAGACTATTTACGCATATATTTCCGATGGAGGTATCCAAGAGGAA
ATCTCCCAAGGTGCCGGACGTATCGCCGGAACTTTAGGACTGGATAACTTGATCATGTTCTACGACGCTAACAACGTGCA
GCTATCTACCAAGGTAGAAGACGTCGATGCGGAGAACGTAGCCATGAAATACGAGGCTTGGGGCTGGAAAGTCATTCAAA
TAAACGGTAACGACATAAACGAGATCCGCAAGGCTTTAAAAGAGGCTAAGGCAGAGATCTCCAAACCGACTTTGATCATC
GGTAACACCGTTATGGGGAAAGGTGCTGTCGGCGCTGATAACAGCTGTTACGAGAATAAGGTATCTACTCACGGACAACC
TTTATCCGCGGCAGGAGCTTCCATCGCAGATACGATCAAGAACCTAGGAGGCGATCCGGAACATCCGTTCGCAATCCTTC
CTGAGGTAGCCGAATTATATGCCAAACGTGCGAAAGAACTGGAAGTAATCGTCGCCGAGCGTTACGCCGTGAAAGACCTC
TGGGCGAAAGCTCACCCGGACTTAGCGGCTAAGATGGAGCAATGGTTCTCCGGTAAGGCTCCTAAAATCGACTGGGCCGC
AATCGAGCAGAAAGCGAACCAAGCGACCCGTGCCGCTTCCGCTACCGTATTAGGTGTGCTTGCTACCCATGTAGAAAACA
TGATCGTAGCTTCCGCCGACCTTTCCAATTCCGATAAGACAGACGGCTTCTTGAAAAAGACTCATGCTTTCGTGAAAGGC
GACTTTAGCGGAGCTTTCTTCCAAGCGGGTGTAGCCGAGCTTTCTATGGCTTGTATCTGTATCGGTATGTCTTTACATGG
TGGCGTGATCGCCGCTTGCGGTACTTTCTTCGTATTCTCCGATTACATGAAGCCTGCGTTACGTATGGCCGCATTGATGG
AGCAGCCCGTTAAGTTCATCTGGACACACGACGCTTTCCGTGTTGGAGAAGACGGACCTACGCACGAGCCGGTAGAGCAA
GAAGCTCAAGTTCGTTTATTAGAGAAATTGAAGAATCATAAGGGACACAACTCCATGTTGGTACTTCGTCCGGCAGACGT
TGTGGAGACAACAGTCGCATGGAAACTAGCGATGGAGAACGTTTACACTCCTACCGCATTGATTCTTTCTCGTCAGAATA
TCACAGATCTTCCCGCTAAGGAAAACCGCTATCAAGAGGCTTTGCAAGCGGAAAAGGGTGCCTATATCGTCAATGAAGAC
GCTAATGCGGATGTAATTCTTTTGGCTTCCGGTTCCGAGGTATCGACTTTGGTCGAGGGCGCCGCCCTGCTTCGTGCCGA
TGGCATAAAGGTTCGTATCGTTTCCGTACCTTCCGAAGGTCTATTCCGTTCACAAAGCAAAGAATACCAAGAATCCATTC
TTCCCGCAGGAAGCAAGATTTTCGGCTTAACCGCTGGTCTTCCGGTTAATCTGGAAGGGTTGGTAGGTCCTAACGGCAAG
GTATGGGGACTTGAATCCTTCGGTTTCTCCGCCCCTTACAAAGTATTGGACGAGAAATTAGGTTTCACGGCTAAGAACGT
TTATAACCAAGTAAAAGAATTATTAGCATAA

Upstream 100 bases:

>100_bases
GATAGGAACCTTTACCGAAAAGGAATTGTTTGATTGATATAACGGCTCTTACAAAGAGTTTGATTATCTTTGCAGTCAAA
TAAATAATTCATCTGATAAA

Downstream 100 bases:

>100_bases
AGATGGGTATAGTAGGTTTGTGTAGCGATCACGCTGGTTTTGAGTTAAAAGAATATATAAAGACAATCCTCGATGAAAGG
GGATTGTCTTATAAAGATTT

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 676; Mature: 676

Protein sequence:

>676_residues
MNDIQVMNKAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFSEFLIYDPKNPKWEGRDRFFLDPGHMSPMLYSVLAL
SGKFTLDELQQFRQWGSVTPGHPEVDVMRGIENTSGPLGQGHTYAVGAAIAAKFLKARLGEEVMNQTIYAYISDGGIQEE
ISQGAGRIAGTLGLDNLIMFYDANNVQLSTKVEDVDAENVAMKYEAWGWKVIQINGNDINEIRKALKEAKAEISKPTLII
GNTVMGKGAVGADNSCYENKVSTHGQPLSAAGASIADTIKNLGGDPEHPFAILPEVAELYAKRAKELEVIVAERYAVKDL
WAKAHPDLAAKMEQWFSGKAPKIDWAAIEQKANQATRAASATVLGVLATHVENMIVASADLSNSDKTDGFLKKTHAFVKG
DFSGAFFQAGVAELSMACICIGMSLHGGVIAACGTFFVFSDYMKPALRMAALMEQPVKFIWTHDAFRVGEDGPTHEPVEQ
EAQVRLLEKLKNHKGHNSMLVLRPADVVETTVAWKLAMENVYTPTALILSRQNITDLPAKENRYQEALQAEKGAYIVNED
ANADVILLASGSEVSTLVEGAALLRADGIKVRIVSVPSEGLFRSQSKEYQESILPAGSKIFGLTAGLPVNLEGLVGPNGK
VWGLESFGFSAPYKVLDEKLGFTAKNVYNQVKELLA

Sequences:

>Translated_676_residues
MNDIQVMNKAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFSEFLIYDPKNPKWEGRDRFFLDPGHMSPMLYSVLAL
SGKFTLDELQQFRQWGSVTPGHPEVDVMRGIENTSGPLGQGHTYAVGAAIAAKFLKARLGEEVMNQTIYAYISDGGIQEE
ISQGAGRIAGTLGLDNLIMFYDANNVQLSTKVEDVDAENVAMKYEAWGWKVIQINGNDINEIRKALKEAKAEISKPTLII
GNTVMGKGAVGADNSCYENKVSTHGQPLSAAGASIADTIKNLGGDPEHPFAILPEVAELYAKRAKELEVIVAERYAVKDL
WAKAHPDLAAKMEQWFSGKAPKIDWAAIEQKANQATRAASATVLGVLATHVENMIVASADLSNSDKTDGFLKKTHAFVKG
DFSGAFFQAGVAELSMACICIGMSLHGGVIAACGTFFVFSDYMKPALRMAALMEQPVKFIWTHDAFRVGEDGPTHEPVEQ
EAQVRLLEKLKNHKGHNSMLVLRPADVVETTVAWKLAMENVYTPTALILSRQNITDLPAKENRYQEALQAEKGAYIVNED
ANADVILLASGSEVSTLVEGAALLRADGIKVRIVSVPSEGLFRSQSKEYQESILPAGSKIFGLTAGLPVNLEGLVGPNGK
VWGLESFGFSAPYKVLDEKLGFTAKNVYNQVKELLA
>Mature_676_residues
MNDIQVMNKAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFSEFLIYDPKNPKWEGRDRFFLDPGHMSPMLYSVLAL
SGKFTLDELQQFRQWGSVTPGHPEVDVMRGIENTSGPLGQGHTYAVGAAIAAKFLKARLGEEVMNQTIYAYISDGGIQEE
ISQGAGRIAGTLGLDNLIMFYDANNVQLSTKVEDVDAENVAMKYEAWGWKVIQINGNDINEIRKALKEAKAEISKPTLII
GNTVMGKGAVGADNSCYENKVSTHGQPLSAAGASIADTIKNLGGDPEHPFAILPEVAELYAKRAKELEVIVAERYAVKDL
WAKAHPDLAAKMEQWFSGKAPKIDWAAIEQKANQATRAASATVLGVLATHVENMIVASADLSNSDKTDGFLKKTHAFVKG
DFSGAFFQAGVAELSMACICIGMSLHGGVIAACGTFFVFSDYMKPALRMAALMEQPVKFIWTHDAFRVGEDGPTHEPVEQ
EAQVRLLEKLKNHKGHNSMLVLRPADVVETTVAWKLAMENVYTPTALILSRQNITDLPAKENRYQEALQAEKGAYIVNED
ANADVILLASGSEVSTLVEGAALLRADGIKVRIVSVPSEGLFRSQSKEYQESILPAGSKIFGLTAGLPVNLEGLVGPNGK
VWGLESFGFSAPYKVLDEKLGFTAKNVYNQVKELLA

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=601, Percent_Identity=25.7903494176373, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI4507521, Length=601, Percent_Identity=25.7903494176373, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI133778974, Length=606, Percent_Identity=25.2475247524752, Blast_Score=120, Evalue=4e-27,
Organism=Escherichia coli, GI48994911, Length=686, Percent_Identity=40.0874635568513, Blast_Score=423, Evalue=1e-119,
Organism=Escherichia coli, GI1788808, Length=683, Percent_Identity=37.7745241581259, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1786304, Length=204, Percent_Identity=28.4313725490196, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17539652, Length=604, Percent_Identity=25.4966887417219, Blast_Score=150, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6325331, Length=687, Percent_Identity=36.8267831149927, Blast_Score=360, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6319593, Length=687, Percent_Identity=34.3522561863173, Blast_Score=328, Evalue=2e-90,
Organism=Drosophila melanogaster, GI45551847, Length=601, Percent_Identity=25.1247920133111, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI45550715, Length=601, Percent_Identity=25.1247920133111, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24666278, Length=611, Percent_Identity=24.0589198036007, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24645119, Length=565, Percent_Identity=25.1327433628319, Blast_Score=129, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 73152; Mature: 73152

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDIQVMNKAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFSEFLIYDPKNPKWEGR
CCCHHHHHHCCCCCEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCCCCC
DRFFLDPGHMSPMLYSVLALSGKFTLDELQQFRQWGSVTPGHPEVDVMRGIENTSGPLGQ
CEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCC
GHTYAVGAAIAAKFLKARLGEEVMNQTIYAYISDGGIQEEISQGAGRIAGTLGLDNLIMF
CCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHCCCCCEEEECCCCCEEEE
YDANNVQLSTKVEDVDAENVAMKYEAWGWKVIQINGNDINEIRKALKEAKAEISKPTLII
EECCCEEEEEEECCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEE
GNTVMGKGAVGADNSCYENKVSTHGQPLSAAGASIADTIKNLGGDPEHPFAILPEVAELY
ECCEECCCCCCCCCCHHHCHHHCCCCCCHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHH
AKRAKELEVIVAERYAVKDLWAKAHPDLAAKMEQWFSGKAPKIDWAAIEQKANQATRAAS
HHHHHHHEEHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
ATVLGVLATHVENMIVASADLSNSDKTDGFLKKTHAFVKGDFSGAFFQAGVAELSMACIC
HHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
IGMSLHGGVIAACGTFFVFSDYMKPALRMAALMEQPVKFIWTHDAFRVGEDGPTHEPVEQ
EEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCEECCCCCCCCCCHHH
EAQVRLLEKLKNHKGHNSMLVLRPADVVETTVAWKLAMENVYTPTALILSRQNITDLPAK
HHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCCC
ENRYQEALQAEKGAYIVNEDANADVILLASGSEVSTLVEGAALLRADGIKVRIVSVPSEG
HHHHHHHHHHCCCCEEEECCCCCCEEEEECCCHHHHHHHHHHHEEECCEEEEEEECCCHH
LFRSQSKEYQESILPAGSKIFGLTAGLPVNLEGLVGPNGKVWGLESFGFSAPYKVLDEKL
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEECCCCCEEEECCCCCCCCHHHHHHHH
GFTAKNVYNQVKELLA
CCHHHHHHHHHHHHHC
>Mature Secondary Structure
MNDIQVMNKAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFSEFLIYDPKNPKWEGR
CCCHHHHHHCCCCCEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCCCCC
DRFFLDPGHMSPMLYSVLALSGKFTLDELQQFRQWGSVTPGHPEVDVMRGIENTSGPLGQ
CEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCC
GHTYAVGAAIAAKFLKARLGEEVMNQTIYAYISDGGIQEEISQGAGRIAGTLGLDNLIMF
CCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHCCCCCEEEECCCCCEEEE
YDANNVQLSTKVEDVDAENVAMKYEAWGWKVIQINGNDINEIRKALKEAKAEISKPTLII
EECCCEEEEEEECCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEE
GNTVMGKGAVGADNSCYENKVSTHGQPLSAAGASIADTIKNLGGDPEHPFAILPEVAELY
ECCEECCCCCCCCCCHHHCHHHCCCCCCHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHH
AKRAKELEVIVAERYAVKDLWAKAHPDLAAKMEQWFSGKAPKIDWAAIEQKANQATRAAS
HHHHHHHEEHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
ATVLGVLATHVENMIVASADLSNSDKTDGFLKKTHAFVKGDFSGAFFQAGVAELSMACIC
HHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
IGMSLHGGVIAACGTFFVFSDYMKPALRMAALMEQPVKFIWTHDAFRVGEDGPTHEPVEQ
EEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCEECCCCCCCCCCHHH
EAQVRLLEKLKNHKGHNSMLVLRPADVVETTVAWKLAMENVYTPTALILSRQNITDLPAK
HHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCCC
ENRYQEALQAEKGAYIVNEDANADVILLASGSEVSTLVEGAALLRADGIKVRIVSVPSEG
HHHHHHHHHHCCCCEEEECCCCCCEEEEECCCHHHHHHHHHHHEEECCEEEEEEECCCHH
LFRSQSKEYQESILPAGSKIFGLTAGLPVNLEGLVGPNGKVWGLESFGFSAPYKVLDEKL
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEECCCCCEEEECCCCCCCCHHHHHHHH
GFTAKNVYNQVKELLA
CCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]