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The map label for this gene is rbsK [H]

Identifier: 150008288

GI number: 150008288

Start: 1957395

End: 1958318

Strand: Reverse

Name: rbsK [H]

Synonym: BDI_1657

Alternate gene names: 150008288

Gene position: 1958318-1957395 (Counterclockwise)

Preceding gene: 150008290

Following gene: 150008287

Centisome position: 40.7

GC content: 46.0

Gene sequence:

>924_bases
ATGAAAGACTTACGGAATCATAATATATTGGTTGTTGGAAGTAGCAATACCGATATGGTCATAAAGACGAATCATCTCCC
TCGTCCGGGAGAGACGGTATTGGGCGGAACATTTTTTATGAACCCGGGTGGGAAAGGAGCGAATCAAGCGGTTGCTGTTG
CGCGGTTAGGGGGACAGGTCTCGTTTATTTGTAAAACAGGCAGTGATATATTCGGACATCAATCCCAGCAGCTATTTGAG
GAAGAGGGGATTGATACTTCCTATATTTTCTCAGATCCGAAGAATCCATCTGGCGTAGCGTTGATTACGGTGGATGCTCA
TGCTGAAAACTGTATTGTGGTGGCCTCCGGAGCTAATGCTAATCTATTACCTTCTGATTTAGCGAAATCGGAAGAGGCGA
TAGAAAAAGCCGATTTGATTTTAATGCAATTGGAGATTCCTATGGATACTGTCGAGTTTGTCGCTAAGATGGCATCGAAG
AAGAACAAACGGGTAATATTGAATCCGGCTCCAGCTCAAACTTTGTCGGCTACGTTACTCCGGCATCTGTATATGATTAC
CCCGAATGAGACAGAGGCAGAGATGATCTCTGGCGTGAAGATCACGGATGAGGTTTCCGCGAAGAAGGCTGCGCAAGTTA
TAATGGAGATGGGAGTACAGAACGTAATCGTTACTTTAGGCTCAAAAGGAGCTTTGATCTATTGTGATTCCATGGTAGAT
ATGGTTCCTGCGATAAAAGTGGAAGCCGTTGATACTACTGCCGCCGGGGATATTTTCAACGGCGCTTTAACGGTGGCTTT
GGCTGAGGGGCGGGATTTAAGGGAAGCCGTGAGATTCGCTTGCAAAGCTTCCGCCATTTCCGTGACTCGTGTGGGAGCGC
AATCTTCCGCTCCTTATCGGAATGAGGTGGATATTTTTGATTAA

Upstream 100 bases:

>100_bases
TTTGCGACATCGGTGAATGAATTTAAATTAACATGAAATCTGGTGTACCAAGCGGAATATATGATATTTTTGTTAAACGA
ATGATTAATAAGAGAAAAGC

Downstream 100 bases:

>100_bases
TCTATAAAAACAATCTAATAGTATGAAACAAACAGTATTTGCGATGATAGCGGGAGTCTCTTTATTTATAGGGGTGACCT
CATGTTCCCAACAACCCTCG

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MKDLRNHNILVVGSSNTDMVIKTNHLPRPGETVLGGTFFMNPGGKGANQAVAVARLGGQVSFICKTGSDIFGHQSQQLFE
EEGIDTSYIFSDPKNPSGVALITVDAHAENCIVVASGANANLLPSDLAKSEEAIEKADLILMQLEIPMDTVEFVAKMASK
KNKRVILNPAPAQTLSATLLRHLYMITPNETEAEMISGVKITDEVSAKKAAQVIMEMGVQNVIVTLGSKGALIYCDSMVD
MVPAIKVEAVDTTAAGDIFNGALTVALAEGRDLREAVRFACKASAISVTRVGAQSSAPYRNEVDIFD

Sequences:

>Translated_307_residues
MKDLRNHNILVVGSSNTDMVIKTNHLPRPGETVLGGTFFMNPGGKGANQAVAVARLGGQVSFICKTGSDIFGHQSQQLFE
EEGIDTSYIFSDPKNPSGVALITVDAHAENCIVVASGANANLLPSDLAKSEEAIEKADLILMQLEIPMDTVEFVAKMASK
KNKRVILNPAPAQTLSATLLRHLYMITPNETEAEMISGVKITDEVSAKKAAQVIMEMGVQNVIVTLGSKGALIYCDSMVD
MVPAIKVEAVDTTAAGDIFNGALTVALAEGRDLREAVRFACKASAISVTRVGAQSSAPYRNEVDIFD
>Mature_307_residues
MKDLRNHNILVVGSSNTDMVIKTNHLPRPGETVLGGTFFMNPGGKGANQAVAVARLGGQVSFICKTGSDIFGHQSQQLFE
EEGIDTSYIFSDPKNPSGVALITVDAHAENCIVVASGANANLLPSDLAKSEEAIEKADLILMQLEIPMDTVEFVAKMASK
KNKRVILNPAPAQTLSATLLRHLYMITPNETEAEMISGVKITDEVSAKKAAQVIMEMGVQNVIVTLGSKGALIYCDSMVD
MVPAIKVEAVDTTAAGDIFNGALTVALAEGRDLREAVRFACKASAISVTRVGAQSSAPYRNEVDIFD

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=302, Percent_Identity=36.7549668874172, Blast_Score=176, Evalue=2e-44,
Organism=Escherichia coli, GI1790193, Length=299, Percent_Identity=45.1505016722408, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI87082343, Length=299, Percent_Identity=31.438127090301, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87081971, Length=278, Percent_Identity=27.3381294964029, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788491, Length=286, Percent_Identity=23.7762237762238, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788017, Length=266, Percent_Identity=28.1954887218045, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788484, Length=289, Percent_Identity=23.5294117647059, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=301, Percent_Identity=39.202657807309, Blast_Score=185, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6319884, Length=329, Percent_Identity=30.3951367781155, Blast_Score=129, Evalue=5e-31,
Organism=Drosophila melanogaster, GI20128807, Length=305, Percent_Identity=34.0983606557377, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24583886, Length=297, Percent_Identity=27.9461279461279, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32668; Mature: 32668

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLRNHNILVVGSSNTDMVIKTNHLPRPGETVLGGTFFMNPGGKGANQAVAVARLGGQV
CCCCCCCCEEEEECCCCCEEEEECCCCCCCCEEECEEEEECCCCCCCCCEEEEEECCCEE
SFICKTGSDIFGHQSQQLFEEEGIDTSYIFSDPKNPSGVALITVDAHAENCIVVASGANA
EEEEECCCHHHCCCHHHHHHHHCCCEEEEECCCCCCCCEEEEEEECCCCCEEEEECCCCC
NLLPSDLAKSEEAIEKADLILMQLEIPMDTVEFVAKMASKKNKRVILNPAPAQTLSATLL
CCCCHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHH
RHLYMITPNETEAEMISGVKITDEVSAKKAAQVIMEMGVQNVIVTLGSKGALIYCDSMVD
HHEEEECCCCCHHHHHCCCEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCHHH
MVPAIKVEAVDTTAAGDIFNGALTVALAEGRDLREAVRFACKASAISVTRVGAQSSAPYR
HCCCEEEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCEEEEEEECCCCCCCCC
NEVDIFD
CCCCCCC
>Mature Secondary Structure
MKDLRNHNILVVGSSNTDMVIKTNHLPRPGETVLGGTFFMNPGGKGANQAVAVARLGGQV
CCCCCCCCEEEEECCCCCEEEEECCCCCCCCEEECEEEEECCCCCCCCCEEEEEECCCEE
SFICKTGSDIFGHQSQQLFEEEGIDTSYIFSDPKNPSGVALITVDAHAENCIVVASGANA
EEEEECCCHHHCCCHHHHHHHHCCCEEEEECCCCCCCCEEEEEEECCCCCEEEEECCCCC
NLLPSDLAKSEEAIEKADLILMQLEIPMDTVEFVAKMASKKNKRVILNPAPAQTLSATLL
CCCCHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHH
RHLYMITPNETEAEMISGVKITDEVSAKKAAQVIMEMGVQNVIVTLGSKGALIYCDSMVD
HHEEEECCCCCHHHHHCCCEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCHHH
MVPAIKVEAVDTTAAGDIFNGALTVALAEGRDLREAVRFACKASAISVTRVGAQSSAPYR
HCCCEEEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCEEEEEEECCCCCCCCC
NEVDIFD
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]