Click here to switch to the map view.

The map label for this gene is luxQ [H]

Identifier: 150008248

GI number: 150008248

Start: 1892261

End: 1894801

Strand: Direct

Name: luxQ [H]

Synonym: BDI_1617

Alternate gene names: 150008248

Gene position: 1892261-1894801 (Clockwise)

Preceding gene: 150008242

Following gene: 150008252

Centisome position: 39.33

GC content: 41.13

Gene sequence:

>2541_bases
ATGAATAACATTCATTCCAATACAACATTTCTTAATGAGGCTATAGACAAGAAGACCGATGTAGAAGATGAAAAGACCGA
CTTGATTTTGGCCAATATGATTGATTTGCGAAAAACGATGTCGGATGTATTGTCACTTCTTCTTGGAGCCAAAAAAAACT
CGGTTATTGACCAAGCGCTATTCCGCATCTTACAATTTTTCGATGTGGATCGGGTGTATATCGGAACATTTGACGAACAA
ACTCATACTGTTGATTTTACGAATGAAGTTACTTGTGATGGCATTATCTCTATGCGAGAGGATTTACTGCGTCAACTCCC
GCAAGACGAGATTCCTTGGTGGTACGACAGTATCAAAAAGGGCATGGATATCGTTATTCATGATGTCTCTAAAATGCCGG
AAGAGGCGAAGAGTGAGCAGCATCTTCTGATTTTGCAAGAGGTTTCATCCTTATTAGTCATCCCTATTTTCAAGCAAGGC
AAACCATCCGGATTTATCGGCTTTGATTCTGTAAAAAAGAAACGGAACTGGAGTGCCTTAGATATAGAGAACTTACATAT
GTTGGCTGATATCCTTTCCATAGCCATTGAAAGAGGGGAAGTTCAAGGATTAGTAGAACATACGGCTATGCAAGTCATGA
AAAGCGAGACGAAGTTTAAGATCATTTTCGACAAGATGCCTTGGGGCGCCGAACTTTATGATGAGAATGGAGTGTTGGTA
GATATCAACCAAGCGGATCTCGATATTTTTGGTGTTACCCGTGAGCAGGCCGTGGGACTGAATATGTTCGAGAATCCTAA
TATCCCGAAATATGTAAACCAAAGCCTCAAAAACGGAAAAGATATATTCTTTCCTCTTAATTATGATTTCAAGGTTGCTT
CTCAAAACGGCTATTACGATAGTCATCATGATTCTAAAACAAAGCATCTGTTGGTAAAAGGAGTCACATTAAAAGACTCT
CTTGATAATATATTCGGCTATATTTATATTGTATTCGACGATACCGAGAATCACATCAAGCGGGAACAAATCGAAAATAG
CCTAGCCCGGCTAAAAGTATCAGTAGATACCGGGGATTCCATTCTTTGGGAATACGATGTAGAGAATGATAAATTGACCG
TAGATTTTGGCCTCAATGAAGACATTAATAATAATGAGGGGCTAAAAGCGATTCATGATTACAACTTCAAGAATCAAGAA
GACTATAAATCCTCAATCCATCCGGATGATTTTGACCGGGTATATAATAAACAGTTCAAACCTCTCCTGCAAGGGAAGAT
CAATAACTTCGTAGCGGCCTACAGGCGTATCCTCAATGGCAAAACATTCTGGTTCAACTCCAATGTACGCTCCTATAAAT
TCAACGATGACGGAACGCCTAACAGGATCGTAAGCTATACCTCCAACATAACCCAGCAACGGGAAAAGGAGATCGAGCTA
ATCAAGGTAAAGGAAGCTGATAAATTGAAGTCCGCATTCTTGGCGAATATGAGTCATGAGATACGCACGCCGCTGAACGC
TATCGTCGGGTTCTCAAATATAATCGCCGAGATTGATGATGAGGTAGAGCGTCAATCTTATTTAGATATCATTCATAAAA
ACAATGATTTGCTACTGCAACTGATCGATGATATCCTTGATTTCTCTAAAATCGAGGCGGGAACCATGGATTATCATTTC
GAGGAAGTGGACATCAAGGATATATGTGGCGAAATCGCATTGGCAGACTCTATAAAGATGCCTTCAGACGTGGTTCTTAT
CTTTGATCTCGGCTCCCCATCCGTAATCGTTAAAACCGATGAGCGGAGGGTTATGCAAGTGATATCTAATTTCGTGAATA
ACGCTATCAAATTTACCACAAAAGGAAGTATCACGATTTATTATGAGATAGAAGGGGATTTTATCCGAGTCTGCGTGAAA
GATACAGGTATCGGTATCTCCGCGGAAAACCAAAGACGTATATTCGAGCGATTCATCAAGGTAGATACTTTCCAGCAAGG
TACGGGATTGGGATTAACCATCAGCCGAACCATTATCGAGGCATTAGGAGGTAAAATCGGCGTAGACTCTGAAGAAGGGG
TGGGTTCCACTTTTTGGTTCACTCTGCCTTTGGACACAAAACGGACTGATATTGAGCTTTCACCGGATATCCCCGTCCAA
TCCGAAGAAACGCCCCGTTCAGATAGGCATCATTCCATCTTAATCGCCGAGGACGTTTATGAGAATTATTTCCTTTTGGA
AACCTTGTTTGGCAAGCAATACCAACTTTATCATGCGCTAAACGGGCAAGAGGCTATCGATATGTTCGAGACATATCATC
CGGACCTAATCCTGATGGACATAAAAATGCCGGTTATGGACGGATTCGAAGCGACTCGCAGAATCCGCACCTTATCCAAG
ACCATTCCGATCATAGCGCTCACGGCATTCGCTTTCGAAAGGGAAAAGGAGATCGCCAAACAATGTGAATTCACGGATTA
TGTAGTGAAGCCCATTGATATAAAAGAACTAAAGAAATTAATCGTTAAGGTATTGGCATAA

Upstream 100 bases:

>100_bases
TTTAAAGCCACGATAATAATATAATAAACACTAAAACAAAAAATAATCAAAGTTTATACTTACATTTGTTTTCGAATAAA
TTTAGTACACTCAATTTATC

Downstream 100 bases:

>100_bases
AAAAGCGTGTTGCGACAATCGCAACACGCTTTTTTTTACTTAGGCATCGGAGCGGCAGAAGGAGGAGGCGTTCCCAATCC
CCATTCCTTATTCGCTTTCG

Product: two-component hybrid sensor kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 846; Mature: 846

Protein sequence:

>846_residues
MNNIHSNTTFLNEAIDKKTDVEDEKTDLILANMIDLRKTMSDVLSLLLGAKKNSVIDQALFRILQFFDVDRVYIGTFDEQ
THTVDFTNEVTCDGIISMREDLLRQLPQDEIPWWYDSIKKGMDIVIHDVSKMPEEAKSEQHLLILQEVSSLLVIPIFKQG
KPSGFIGFDSVKKKRNWSALDIENLHMLADILSIAIERGEVQGLVEHTAMQVMKSETKFKIIFDKMPWGAELYDENGVLV
DINQADLDIFGVTREQAVGLNMFENPNIPKYVNQSLKNGKDIFFPLNYDFKVASQNGYYDSHHDSKTKHLLVKGVTLKDS
LDNIFGYIYIVFDDTENHIKREQIENSLARLKVSVDTGDSILWEYDVENDKLTVDFGLNEDINNNEGLKAIHDYNFKNQE
DYKSSIHPDDFDRVYNKQFKPLLQGKINNFVAAYRRILNGKTFWFNSNVRSYKFNDDGTPNRIVSYTSNITQQREKEIEL
IKVKEADKLKSAFLANMSHEIRTPLNAIVGFSNIIAEIDDEVERQSYLDIIHKNNDLLLQLIDDILDFSKIEAGTMDYHF
EEVDIKDICGEIALADSIKMPSDVVLIFDLGSPSVIVKTDERRVMQVISNFVNNAIKFTTKGSITIYYEIEGDFIRVCVK
DTGIGISAENQRRIFERFIKVDTFQQGTGLGLTISRTIIEALGGKIGVDSEEGVGSTFWFTLPLDTKRTDIELSPDIPVQ
SEETPRSDRHHSILIAEDVYENYFLLETLFGKQYQLYHALNGQEAIDMFETYHPDLILMDIKMPVMDGFEATRRIRTLSK
TIPIIALTAFAFEREKEIAKQCEFTDYVVKPIDIKELKKLIVKVLA

Sequences:

>Translated_846_residues
MNNIHSNTTFLNEAIDKKTDVEDEKTDLILANMIDLRKTMSDVLSLLLGAKKNSVIDQALFRILQFFDVDRVYIGTFDEQ
THTVDFTNEVTCDGIISMREDLLRQLPQDEIPWWYDSIKKGMDIVIHDVSKMPEEAKSEQHLLILQEVSSLLVIPIFKQG
KPSGFIGFDSVKKKRNWSALDIENLHMLADILSIAIERGEVQGLVEHTAMQVMKSETKFKIIFDKMPWGAELYDENGVLV
DINQADLDIFGVTREQAVGLNMFENPNIPKYVNQSLKNGKDIFFPLNYDFKVASQNGYYDSHHDSKTKHLLVKGVTLKDS
LDNIFGYIYIVFDDTENHIKREQIENSLARLKVSVDTGDSILWEYDVENDKLTVDFGLNEDINNNEGLKAIHDYNFKNQE
DYKSSIHPDDFDRVYNKQFKPLLQGKINNFVAAYRRILNGKTFWFNSNVRSYKFNDDGTPNRIVSYTSNITQQREKEIEL
IKVKEADKLKSAFLANMSHEIRTPLNAIVGFSNIIAEIDDEVERQSYLDIIHKNNDLLLQLIDDILDFSKIEAGTMDYHF
EEVDIKDICGEIALADSIKMPSDVVLIFDLGSPSVIVKTDERRVMQVISNFVNNAIKFTTKGSITIYYEIEGDFIRVCVK
DTGIGISAENQRRIFERFIKVDTFQQGTGLGLTISRTIIEALGGKIGVDSEEGVGSTFWFTLPLDTKRTDIELSPDIPVQ
SEETPRSDRHHSILIAEDVYENYFLLETLFGKQYQLYHALNGQEAIDMFETYHPDLILMDIKMPVMDGFEATRRIRTLSK
TIPIIALTAFAFEREKEIAKQCEFTDYVVKPIDIKELKKLIVKVLA
>Mature_846_residues
MNNIHSNTTFLNEAIDKKTDVEDEKTDLILANMIDLRKTMSDVLSLLLGAKKNSVIDQALFRILQFFDVDRVYIGTFDEQ
THTVDFTNEVTCDGIISMREDLLRQLPQDEIPWWYDSIKKGMDIVIHDVSKMPEEAKSEQHLLILQEVSSLLVIPIFKQG
KPSGFIGFDSVKKKRNWSALDIENLHMLADILSIAIERGEVQGLVEHTAMQVMKSETKFKIIFDKMPWGAELYDENGVLV
DINQADLDIFGVTREQAVGLNMFENPNIPKYVNQSLKNGKDIFFPLNYDFKVASQNGYYDSHHDSKTKHLLVKGVTLKDS
LDNIFGYIYIVFDDTENHIKREQIENSLARLKVSVDTGDSILWEYDVENDKLTVDFGLNEDINNNEGLKAIHDYNFKNQE
DYKSSIHPDDFDRVYNKQFKPLLQGKINNFVAAYRRILNGKTFWFNSNVRSYKFNDDGTPNRIVSYTSNITQQREKEIEL
IKVKEADKLKSAFLANMSHEIRTPLNAIVGFSNIIAEIDDEVERQSYLDIIHKNNDLLLQLIDDILDFSKIEAGTMDYHF
EEVDIKDICGEIALADSIKMPSDVVLIFDLGSPSVIVKTDERRVMQVISNFVNNAIKFTTKGSITIYYEIEGDFIRVCVK
DTGIGISAENQRRIFERFIKVDTFQQGTGLGLTISRTIIEALGGKIGVDSEEGVGSTFWFTLPLDTKRTDIELSPDIPVQ
SEETPRSDRHHSILIAEDVYENYFLLETLFGKQYQLYHALNGQEAIDMFETYHPDLILMDIKMPVMDGFEATRRIRTLSK
TIPIIALTAFAFEREKEIAKQCEFTDYVVKPIDIKELKKLIVKVLA

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=380, Percent_Identity=32.6315789473684, Blast_Score=182, Evalue=1e-46,
Organism=Escherichia coli, GI48994928, Length=403, Percent_Identity=28.5359801488834, Blast_Score=156, Evalue=5e-39,
Organism=Escherichia coli, GI87081816, Length=423, Percent_Identity=28.8416075650118, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1789149, Length=263, Percent_Identity=34.6007604562738, Blast_Score=147, Evalue=3e-36,
Organism=Escherichia coli, GI145693157, Length=231, Percent_Identity=37.2294372294372, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=27.7551020408163, Blast_Score=93, Evalue=8e-20,
Organism=Escherichia coli, GI1786600, Length=248, Percent_Identity=26.2096774193548, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=28.5123966942149, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=26.8398268398268, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1788550, Length=114, Percent_Identity=37.719298245614, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788393, Length=257, Percent_Identity=25.2918287937743, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1787894, Length=219, Percent_Identity=26.027397260274, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1790861, Length=255, Percent_Identity=24.3137254901961, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786783, Length=227, Percent_Identity=26.431718061674, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI87082128, Length=226, Percent_Identity=24.7787610619469, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1789808, Length=227, Percent_Identity=25.1101321585903, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 96996; Mature: 96996

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIHSNTTFLNEAIDKKTDVEDEKTDLILANMIDLRKTMSDVLSLLLGAKKNSVIDQAL
CCCCCCCHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
FRILQFFDVDRVYIGTFDEQTHTVDFTNEVTCDGIISMREDLLRQLPQDEIPWWYDSIKK
HHHHHHHCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHC
GMDIVIHDVSKMPEEAKSEQHLLILQEVSSLLVIPIFKQGKPSGFIGFDSVKKKRNWSAL
CCEEEEECHHHCCHHHCCCCEEEEHHHHCCEEEEEEECCCCCCCEECHHHHHHCCCCCCC
DIENLHMLADILSIAIERGEVQGLVEHTAMQVMKSETKFKIIFDKMPWGAELYDENGVLV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEECCCCEEE
DINQADLDIFGVTREQAVGLNMFENPNIPKYVNQSLKNGKDIFFPLNYDFKVASQNGYYD
EECCCCEEEEECCHHHHCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCEEECCCCCCCC
SHHDSKTKHLLVKGVTLKDSLDNIFGYIYIVFDDTENHIKREQIENSLARLKVSVDTGDS
CCCCCCCEEEEEECCCHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHHEEEEEECCCCC
ILWEYDVENDKLTVDFGLNEDINNNEGLKAIHDYNFKNQEDYKSSIHPDDFDRVYNKQFK
EEEEEECCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCHHHHHCCCCCHHHHHHHHHHH
PLLQGKINNFVAAYRRILNGKTFWFNSNVRSYKFNDDGTPNRIVSYTSNITQQREKEIEL
HHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEE
IKVKEADKLKSAFLANMSHEIRTPLNAIVGFSNIIAEIDDEVERQSYLDIIHKNNDLLLQ
EEECCHHHHHHHHHHHCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LIDDILDFSKIEAGTMDYHFEEVDIKDICGEIALADSIKMPSDVVLIFDLGSPSVIVKTD
HHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECC
ERRVMQVISNFVNNAIKFTTKGSITIYYEIEGDFIRVCVKDTGIGISAENQRRIFERFIK
HHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHH
VDTFQQGTGLGLTISRTIIEALGGKIGVDSEEGVGSTFWFTLPLDTKRTDIELSPDIPVQ
HCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEECCCCCCC
SEETPRSDRHHSILIAEDVYENYFLLETLFGKQYQLYHALNGQEAIDMFETYHPDLILMD
CCCCCCCCCCCEEEEEHHHHCCEEHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCEEEEE
IKMPVMDGFEATRRIRTLSKTIPIIALTAFAFEREKEIAKQCEFTDYVVKPIDIKELKKL
ECCCHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHEECCCCHHHHHHH
IVKVLA
HHHHHC
>Mature Secondary Structure
MNNIHSNTTFLNEAIDKKTDVEDEKTDLILANMIDLRKTMSDVLSLLLGAKKNSVIDQAL
CCCCCCCHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
FRILQFFDVDRVYIGTFDEQTHTVDFTNEVTCDGIISMREDLLRQLPQDEIPWWYDSIKK
HHHHHHHCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHC
GMDIVIHDVSKMPEEAKSEQHLLILQEVSSLLVIPIFKQGKPSGFIGFDSVKKKRNWSAL
CCEEEEECHHHCCHHHCCCCEEEEHHHHCCEEEEEEECCCCCCCEECHHHHHHCCCCCCC
DIENLHMLADILSIAIERGEVQGLVEHTAMQVMKSETKFKIIFDKMPWGAELYDENGVLV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEECCCCEEE
DINQADLDIFGVTREQAVGLNMFENPNIPKYVNQSLKNGKDIFFPLNYDFKVASQNGYYD
EECCCCEEEEECCHHHHCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCEEECCCCCCCC
SHHDSKTKHLLVKGVTLKDSLDNIFGYIYIVFDDTENHIKREQIENSLARLKVSVDTGDS
CCCCCCCEEEEEECCCHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHHEEEEEECCCCC
ILWEYDVENDKLTVDFGLNEDINNNEGLKAIHDYNFKNQEDYKSSIHPDDFDRVYNKQFK
EEEEEECCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCHHHHHCCCCCHHHHHHHHHHH
PLLQGKINNFVAAYRRILNGKTFWFNSNVRSYKFNDDGTPNRIVSYTSNITQQREKEIEL
HHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEE
IKVKEADKLKSAFLANMSHEIRTPLNAIVGFSNIIAEIDDEVERQSYLDIIHKNNDLLLQ
EEECCHHHHHHHHHHHCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LIDDILDFSKIEAGTMDYHFEEVDIKDICGEIALADSIKMPSDVVLIFDLGSPSVIVKTD
HHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECC
ERRVMQVISNFVNNAIKFTTKGSITIYYEIEGDFIRVCVKDTGIGISAENQRRIFERFIK
HHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHH
VDTFQQGTGLGLTISRTIIEALGGKIGVDSEEGVGSTFWFTLPLDTKRTDIELSPDIPVQ
HCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEECCCCCCC
SEETPRSDRHHSILIAEDVYENYFLLETLFGKQYQLYHALNGQEAIDMFETYHPDLILMD
CCCCCCCCCCCEEEEEHHHHCCEEHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCEEEEE
IKMPVMDGFEATRRIRTLSKTIPIIALTAFAFEREKEIAKQCEFTDYVVKPIDIKELKKL
ECCCHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHEECCCCHHHHHHH
IVKVLA
HHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA