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The map label for this gene is ppiA [C]

Identifier: 150008203

GI number: 150008203

Start: 1836930

End: 1837601

Strand: Direct

Name: ppiA [C]

Synonym: BDI_1569

Alternate gene names: 150008203

Gene position: 1836930-1837601 (Clockwise)

Preceding gene: 150008199

Following gene: 150008204

Centisome position: 38.18

GC content: 46.43

Gene sequence:

>672_bases
ATGAGACGGATTCTTACGATGTTGTTTGTTTCGGTATTTATGCTTTCGCTATGCCCGCTGCATGCGCAAGAGACTGAGAC
ATTGGTGCTGATTGATACGGATATGGGTAAGATTAAGGTGAAACTGTTCAACGACACGCCGTTGCACAGGGATAATTTTA
TCAAGAACGTAAAAGAACACCGTTACGATGGATTATTGTTCCATCGGGTTATCAAGCAATTCATGATACAAGGAGGCGAT
ATCAACTCGAAAGACGCTCCCTTGGACGCACATCTGGGCGACGGAGATCTAGATTACACCATCCCCGCCGAGTTCGTGTA
TCCGAAATATTTCCATAAGCGGGGAATGCTCTGTGCCGCACGTACCCCGGATGAGGAGAATCCCGAGAAGGCCTCATCAG
CGACTCAATTCTATATCGTAACCGGAAAGTTCTTTACGGAGATGGAGCTAGATAAGATGACCAAGGAGAAAGGCATCAAG
TTTACGCCGGAGCAAAAAGAAGCCTATATGCTGGAAGGCGGAACGCCTCATCTGGACGGCAACTATACGGTGTTCGGAGA
GGTTATACAGGGTATGAAAGTCGTGGATAAGATACAGTTCGTCGAGACGAACGCCGAAGACAGGCCCACGAAGAACATAA
AGATCAAGTCAATGAAACTCATAGAAAAATAA

Upstream 100 bases:

>100_bases
CGGTTTCCTACCAAAGAAATCATGTTTAGACCTATTCCTTTGATCATAGATATCGATATTTATTCTTATTTTTGTCCATC
TAAAACTAATAGAAATAAAT

Downstream 100 bases:

>100_bases
GTAAAATGGAAAATCAAGCAACTGAGACAAAGGTGCTTATGCACACCAACAAAGGAGATATAAAGTTGAAATTATATAAC
GACACGCCATTACATCGTGA

Product: cyclophilin-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Phosphatase; Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MRRILTMLFVSVFMLSLCPLHAQETETLVLIDTDMGKIKVKLFNDTPLHRDNFIKNVKEHRYDGLLFHRVIKQFMIQGGD
INSKDAPLDAHLGDGDLDYTIPAEFVYPKYFHKRGMLCAARTPDEENPEKASSATQFYIVTGKFFTEMELDKMTKEKGIK
FTPEQKEAYMLEGGTPHLDGNYTVFGEVIQGMKVVDKIQFVETNAEDRPTKNIKIKSMKLIEK

Sequences:

>Translated_223_residues
MRRILTMLFVSVFMLSLCPLHAQETETLVLIDTDMGKIKVKLFNDTPLHRDNFIKNVKEHRYDGLLFHRVIKQFMIQGGD
INSKDAPLDAHLGDGDLDYTIPAEFVYPKYFHKRGMLCAARTPDEENPEKASSATQFYIVTGKFFTEMELDKMTKEKGIK
FTPEQKEAYMLEGGTPHLDGNYTVFGEVIQGMKVVDKIQFVETNAEDRPTKNIKIKSMKLIEK
>Mature_223_residues
MRRILTMLFVSVFMLSLCPLHAQETETLVLIDTDMGKIKVKLFNDTPLHRDNFIKNVKEHRYDGLLFHRVIKQFMIQGGD
INSKDAPLDAHLGDGDLDYTIPAEFVYPKYFHKRGMLCAARTPDEENPEKASSATQFYIVTGKFFTEMELDKMTKEKGIK
FTPEQKEAYMLEGGTPHLDGNYTVFGEVIQGMKVVDKIQFVETNAEDRPTKNIKIKSMKLIEK

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150
- InterPro:   IPR002130 [H]

Pfam domain/function: PF08282 Hydrolase_3; PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 25631; Mature: 25631

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRILTMLFVSVFMLSLCPLHAQETETLVLIDTDMGKIKVKLFNDTPLHRDNFIKNVKEH
CHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHH
RYDGLLFHRVIKQFMIQGGDINSKDAPLDAHLGDGDLDYTIPAEFVYPKYFHKRGMLCAA
HCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCHHHCCHHHHHHCCCEEEE
RTPDEENPEKASSATQFYIVTGKFFTEMELDKMTKEKGIKFTPEQKEAYMLEGGTPHLDG
CCCCCCCCHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCEECCCCCCEEEECCCCCCCCC
NYTVFGEVIQGMKVVDKIQFVETNAEDRPTKNIKIKSMKLIEK
CEEEHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEHEEECCC
>Mature Secondary Structure
MRRILTMLFVSVFMLSLCPLHAQETETLVLIDTDMGKIKVKLFNDTPLHRDNFIKNVKEH
CHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHH
RYDGLLFHRVIKQFMIQGGDINSKDAPLDAHLGDGDLDYTIPAEFVYPKYFHKRGMLCAA
HCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCHHHCCHHHHHHCCCEEEE
RTPDEENPEKASSATQFYIVTGKFFTEMELDKMTKEKGIKFTPEQKEAYMLEGGTPHLDG
CCCCCCCCHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCEECCCCCCEEEECCCCCCCCC
NYTVFGEVIQGMKVVDKIQFVETNAEDRPTKNIKIKSMKLIEK
CEEEHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA