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The map label for this gene is dapL [H]

Identifier: 150008015

GI number: 150008015

Start: 1598082

End: 1599260

Strand: Direct

Name: dapL [H]

Synonym: BDI_1378

Alternate gene names: 150008015

Gene position: 1598082-1599260 (Clockwise)

Preceding gene: 150008014

Following gene: 150008016

Centisome position: 33.21

GC content: 50.21

Gene sequence:

>1179_bases
ATGCAGAAGGAAAACAAAGCGTGTAATATTACACCCGCTAACCGTGTAGGTAGCGTACAGGAATACTACTTCTCCAAGAA
GCTGAAGGAAGTAGCCGAGATGAACGCCGCAGGCAAGAACGTCATTAACCTTGGCGTAGGCAGCCCCGACCTTCCACCTT
CGGAACAGACCATCGAGACGTTGTGTGAACATGCCCGCAAAGCGAACGAGCACGGTTATCAGCCGTACGTGGGCATACCG
GAACTGCGTAAGGGATTCGCCGATTGGTACAAGACGTGGTATAACGTAGACTTGGACCCGAAAACAGAGATCCAACCACT
CATCGGCTCCAAAGAAGGTATCTTGCATATCTCGCTGGCATTCTTGAATCCGGGGGATGGCGTACTGGTTCCGAACCCGG
GATATCCGACATATAGTTCCGTCAGCAAGCTAGTAGAGGCTCGTTTGATCCCTTACGAGTTGAAAGAGGAATTGGGATGG
CAACCGGATTTCGAGGAACTGGAGAAAATGGATCTCTCCAACGTAAAGCTGATGTGGACCAATTACCCGAATATGCCCAC
AGGGGCGAACGCTAGCGTAGAGCTATACGAGAAACTGGTGGCCTTCGGCCGGAAGCACGGTATTATTATATGTAATGATA
ACCCCTATAGCTTCATCTTGAACGAGCATCCGCTAAGTATCTTAAGCATACCGGGAGCCAAAGAGATCTGTATCGAGATG
AACTCCATGAGTAAGGCTCATAATATGCCGGGTTGGCGTATGGCGATGCTGGCTTCCAACGCCCAATTCGTCCAATGGAT
ACTGAAGGTAAAAAGCAATATCGACTCCGGGCAGTTCAAGCCGATGCAATATGCGGCGGTAGAGGCCCTAAGCGCAAAGA
AAGAGTGGTACGACAATATGAACCGTGTCTATCGTAGCCGCCGGAACCTTGCCGGACAAATCATGCGTACTTTGGGATGC
GAGTACGACGAGAACCAAGTAGGTATGTTCCTTTGGGGACGTATCCCCGACTCCGCCGAGAGCGGCGAGGCAATCGCCAA
CAAGGTGCTATACGAGGCAAACGTATTCCTTACGCCGGGATTTATCTTCGGTAGCCGTGGCGAGCGTTATATCCGTATCT
CCCTTTGCTGCAAGAACGAGACTTTAGAAGAAGCCTTGAAGAGAATTGAGAATTTATAA

Upstream 100 bases:

>100_bases
TTGTTCTACATTGATCTTACTTTCACGGATTTCACCCGTTACAAACAAGCGTTGGACGCTATCAGACCATTAACAAAAGA
CTTAAAAATATTAGGCGAAT

Downstream 100 bases:

>100_bases
CTGAAAATTGAAAATTAAAATATAGATCACAAAGATGGAAATGAAGATTGAACCGTTAGCATTACCGGGAGTTGACACAC
AACGTCCTATCGTAATCGCA

Product: putative aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MQKENKACNITPANRVGSVQEYYFSKKLKEVAEMNAAGKNVINLGVGSPDLPPSEQTIETLCEHARKANEHGYQPYVGIP
ELRKGFADWYKTWYNVDLDPKTEIQPLIGSKEGILHISLAFLNPGDGVLVPNPGYPTYSSVSKLVEARLIPYELKEELGW
QPDFEELEKMDLSNVKLMWTNYPNMPTGANASVELYEKLVAFGRKHGIIICNDNPYSFILNEHPLSILSIPGAKEICIEM
NSMSKAHNMPGWRMAMLASNAQFVQWILKVKSNIDSGQFKPMQYAAVEALSAKKEWYDNMNRVYRSRRNLAGQIMRTLGC
EYDENQVGMFLWGRIPDSAESGEAIANKVLYEANVFLTPGFIFGSRGERYIRISLCCKNETLEEALKRIENL

Sequences:

>Translated_392_residues
MQKENKACNITPANRVGSVQEYYFSKKLKEVAEMNAAGKNVINLGVGSPDLPPSEQTIETLCEHARKANEHGYQPYVGIP
ELRKGFADWYKTWYNVDLDPKTEIQPLIGSKEGILHISLAFLNPGDGVLVPNPGYPTYSSVSKLVEARLIPYELKEELGW
QPDFEELEKMDLSNVKLMWTNYPNMPTGANASVELYEKLVAFGRKHGIIICNDNPYSFILNEHPLSILSIPGAKEICIEM
NSMSKAHNMPGWRMAMLASNAQFVQWILKVKSNIDSGQFKPMQYAAVEALSAKKEWYDNMNRVYRSRRNLAGQIMRTLGC
EYDENQVGMFLWGRIPDSAESGEAIANKVLYEANVFLTPGFIFGSRGERYIRISLCCKNETLEEALKRIENL
>Mature_392_residues
MQKENKACNITPANRVGSVQEYYFSKKLKEVAEMNAAGKNVINLGVGSPDLPPSEQTIETLCEHARKANEHGYQPYVGIP
ELRKGFADWYKTWYNVDLDPKTEIQPLIGSKEGILHISLAFLNPGDGVLVPNPGYPTYSSVSKLVEARLIPYELKEELGW
QPDFEELEKMDLSNVKLMWTNYPNMPTGANASVELYEKLVAFGRKHGIIICNDNPYSFILNEHPLSILSIPGAKEICIEM
NSMSKAHNMPGWRMAMLASNAQFVQWILKVKSNIDSGQFKPMQYAAVEALSAKKEWYDNMNRVYRSRRNLAGQIMRTLGC
EYDENQVGMFLWGRIPDSAESGEAIANKVLYEANVFLTPGFIFGSRGERYIRISLCCKNETLEEALKRIENL

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=275, Percent_Identity=26.1818181818182, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI169881279, Length=275, Percent_Identity=26.1818181818182, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI56713254, Length=267, Percent_Identity=25.8426966292135, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI56713256, Length=267, Percent_Identity=25.8426966292135, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI4507369, Length=226, Percent_Identity=25.2212389380531, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1788722, Length=387, Percent_Identity=31.0077519379845, Blast_Score=227, Evalue=9e-61,
Organism=Escherichia coli, GI1788627, Length=236, Percent_Identity=27.9661016949153, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786816, Length=283, Percent_Identity=24.3816254416961, Blast_Score=82, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71994472, Length=266, Percent_Identity=27.8195488721804, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71994476, Length=266, Percent_Identity=27.8195488721804, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17567663, Length=374, Percent_Identity=26.4705882352941, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17567369, Length=424, Percent_Identity=23.1132075471698, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=23.9074550128535, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28573069, Length=310, Percent_Identity=21.2903225806452, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24646114, Length=310, Percent_Identity=21.2903225806452, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28573067, Length=310, Percent_Identity=21.2903225806452, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28573065, Length=310, Percent_Identity=21.2903225806452, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI18859735, Length=382, Percent_Identity=22.7748691099476, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 44337; Mature: 44337

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKENKACNITPANRVGSVQEYYFSKKLKEVAEMNAAGKNVINLGVGSPDLPPSEQTIET
CCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHH
LCEHARKANEHGYQPYVGIPELRKGFADWYKTWYNVDLDPKTEIQPLIGSKEGILHISLA
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCEEEEEEE
FLNPGDGVLVPNPGYPTYSSVSKLVEARLIPYELKEELGWQPDFEELEKMDLSNVKLMWT
EECCCCCEEECCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHCCCCCEEEEEE
NYPNMPTGANASVELYEKLVAFGRKHGIIICNDNPYSFILNEHPLSILSIPGAKEICIEM
CCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCEEEEECCCCHHHHEEH
NSMSKAHNMPGWRMAMLASNAQFVQWILKVKSNIDSGQFKPMQYAAVEALSAKKEWYDNM
HHHHHHHCCCCCEEHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
NRVYRSRRNLAGQIMRTLGCEYDENQVGMFLWGRIPDSAESGEAIANKVLYEANVFLTPG
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCEEEEECC
FIFGSRGERYIRISLCCKNETLEEALKRIENL
EEECCCCCEEEEEEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure
MQKENKACNITPANRVGSVQEYYFSKKLKEVAEMNAAGKNVINLGVGSPDLPPSEQTIET
CCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHH
LCEHARKANEHGYQPYVGIPELRKGFADWYKTWYNVDLDPKTEIQPLIGSKEGILHISLA
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCEEEEEEE
FLNPGDGVLVPNPGYPTYSSVSKLVEARLIPYELKEELGWQPDFEELEKMDLSNVKLMWT
EECCCCCEEECCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHCCCCCEEEEEE
NYPNMPTGANASVELYEKLVAFGRKHGIIICNDNPYSFILNEHPLSILSIPGAKEICIEM
CCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCEEEEECCCCHHHHEEH
NSMSKAHNMPGWRMAMLASNAQFVQWILKVKSNIDSGQFKPMQYAAVEALSAKKEWYDNM
HHHHHHHCCCCCEEHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
NRVYRSRRNLAGQIMRTLGCEYDENQVGMFLWGRIPDSAESGEAIANKVLYEANVFLTPG
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCEEEEECC
FIFGSRGERYIRISLCCKNETLEEALKRIENL
EEECCCCCEEEEEEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA