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The map label for this gene is clpB [H]

Identifier: 150007863

GI number: 150007863

Start: 1416275

End: 1418863

Strand: Reverse

Name: clpB [H]

Synonym: BDI_1223

Alternate gene names: 150007863

Gene position: 1418863-1416275 (Counterclockwise)

Preceding gene: 150007864

Following gene: 150007861

Centisome position: 29.49

GC content: 49.4

Gene sequence:

>2589_bases
ATGAATTTAAACAATTTTACAATCAAGGCGCAGGAGGCTGTTCAACAAGCCGTACAGTTGGTTACTAAAAATAACCAACA
GGTTATCGAACCTGTTCACTTGTTGAAAGCTGTCATTATGACGGGTGAGAGTGTTACTAATTTTATCTTTCAAAAATTAG
GGGTAAACGCTCAAAACCTGAATATGGTACTGGATCGCCAAATCGAATCTTATCCTAAGGTTTCGGGAGGCGAACCCTAT
CTCTCTAGCGAGTCGAACGCTGTCTTACAGAAGGCGATCGATTATTCCTCTAAAATGGGGGATCAATATGTATCGTTGGA
GCCGATCATCTTGGCGTTGTTTACGGAAAAGAGCACCGCTTCACAGATATTGAAAGACGCCGGCGTGACAGAGAAAGAGT
TACGTCAAGCGATCGAGGAATTGCGTAAAGGAAATAAGGTGACAAGCCAATCCGCCGAGGAGACTTACGATGCCTTAGGA
AAATACGCCATCAATTTGAACGAGCGTGCCCGTAGCGGTAAGCTAGACCCCGTGATCGGACGTGACGAGGAGATCCGCCG
TGTCTTGCAGATATTGAGCCGCCGTACGAAGAACAATCCGATCTTGATCGGTGAGCCGGGTGTAGGTAAGACTGCTATCG
CTGAGGGGTTGGCCCATCGTATCGTTCGGGGTGACGTTCCTGAGAACTTGAAGTCTAAACAGATCTTCTCGTTGGATATG
GGCGCGTTGATCGCCGGAGCTAAATATAAAGGCGAGTTCGAGGAACGTTTGAAAGCGGTGGTGAACGAGGTTACGAAATC
CGAGGGCGAGATCATCCTCTTTATCGATGAGATCCATACCTTGGTAGGAGCCGGTAAAGGCGAAGGCGCCATGGATGCCG
CTAACATCTTGAAACCGGCCTTGGCTCGTGGTGAGCTACGTTCGATCGGTGCCACGACGTTGGATGAGTATCAGAAGTAT
TTTGAGAAGGATAAGGCGCTTGAGCGTCGGTTCCAGACCGTTATCGTAGACGAGCCGAGTGAGTTGGATACGATCTCCAT
CCTTCGTGGTTTGAAGGAGAAATATGAGAATCACCATAAAGTACGTATCAAAGATGATGCGATTATCTCTGCCGTACAGT
TGTCTACCCGTTATATCACGGATCGTTTCTTGCCGGATAAGGCGATCGATTTGATGGATGAGGCCGCTGCCCGTCTGCGT
TTGCAGATCGATTCCGTACCGGAGTCGTTGGATGAGGTTTCCCGCCGTATCAAACAGTTGGAAATCGAGCGTGAGGCGAT
CAAGCGTGAGAACGATACCTCGAAGTTGGAGCAACTCAACAAAGAGATCGCCGACTTGAAGGAGGAGGAGACCAAGCAAA
AGGCTCAGTGGCAGAGCGAGAAGGAGCAGATCAATAAGATCCAGCAAAATAAGATCGATATCGAGAACCTAAAGTTTGAG
GCTGATAAGGCGGAGCGTGAGGGTGATTACGGCAAGGTCGCTGAGATCCGTTACGGTAAGATCAAGCAAAAGGAAGAGGA
GATCAGGGAGGTACAGGCTAAGTTGAAGACGATGCAAGGTGCCGCGGCTATGATCAAGGAGGAAGTGGATAGCGACGATA
TCGCCGATGTGGTATCCCGTTGGACTGGAATTCCGGTCAGCAAGATGATGCAGAGCGAGAAAGATAAGTTATTACGTCTG
GAGTCCGAGCTTCATACCCGTGTGATTGGTCAGGAAGAGGCGATCAACGCTATCGCCGATGCGGTTCGTCGTAGTCGTGC
CGGCTTGCAGGATCCGAAACGACCGATCGGTTCTTTCATCTTCCTCGGTACTACCGGTGTGGGTAAGACGGAGTTGGCCA
AGGCATTGGCCGAGTATCTGTTCGATGACGAGAATATGATGACCCGTATCGACATGAGTGAGTATCAAGAGAAATTCAGC
GCGACTCGTTTGATCGGTGCGCCTCCGGGATATGTGGGCTACGATGAGGGTGGACAGTTGACGGAGGCGATTCGCCGGAA
ACCTTACTCGGTTGTCTTGTTCGATGAGATCGAAAAGGCGCATCCGGATGTATTCAATATCTTGTTGCAAGTCTTGGATG
ATGGACGGTTGACGGATAACAAAGGCCGTGTTGTCAACTTCAAGAACACGATCATTATCATGACAAGTAACCTAGGTTCT
TCCTTGATCCGTGAGAACTTCGAGAAGATGACACCCGCCACGCATGACAAGGTGGTAGACGAGACGAAGATCCAAGTACT
GGAACTGTTGAAGAAGACGATCCGTCCGGAGTTCTTGAACCGTATCGACGATATCATCATGTTTACTCCGCTGAACGAGG
AGGAGATTCGCAAGATCGTATCCTTGCAGTTGAGCAGCGTGAAGAAGATGTTGGCTACGAACGGTGTCGCCTTGGACTTC
ACGAACGAGGCCGTGGACTTTATCGCCGACAAGGGCTTCGATCCTCAATTCGGTGCCCGTCCGGTAAAACGTGTCATTCA
GAAGTATGTCTTGAACGAGTTGTCAAAGGCTTTGCTGGGTGGAACGGTAGACCGTAACCGTCCGATCGTGATCGATAGGA
AAGACGATGGTCTGGAATTTAAGAACTAA

Upstream 100 bases:

>100_bases
TATTAAGACAAAATGTCATATTTTCGTTTTGGTATTTCTTTTGTAAGGATATAAGTGTAAAATAAAATTAGAAAAGAATA
TAAGAAAGGAGCTTAAATAC

Downstream 100 bases:

>100_bases
AGTAGACTTGAACGCTTGACGTTAAGCGTGGTGTTTCTATAAAATAATGAAGGTGGAATGATCCTATGTGAATCATTCCG
CCTTTTTATTTTTCACTAAT

Product: endopeptidase Clp ATP-binding chain B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 862; Mature: 862

Protein sequence:

>862_residues
MNLNNFTIKAQEAVQQAVQLVTKNNQQVIEPVHLLKAVIMTGESVTNFIFQKLGVNAQNLNMVLDRQIESYPKVSGGEPY
LSSESNAVLQKAIDYSSKMGDQYVSLEPIILALFTEKSTASQILKDAGVTEKELRQAIEELRKGNKVTSQSAEETYDALG
KYAINLNERARSGKLDPVIGRDEEIRRVLQILSRRTKNNPILIGEPGVGKTAIAEGLAHRIVRGDVPENLKSKQIFSLDM
GALIAGAKYKGEFEERLKAVVNEVTKSEGEIILFIDEIHTLVGAGKGEGAMDAANILKPALARGELRSIGATTLDEYQKY
FEKDKALERRFQTVIVDEPSELDTISILRGLKEKYENHHKVRIKDDAIISAVQLSTRYITDRFLPDKAIDLMDEAAARLR
LQIDSVPESLDEVSRRIKQLEIEREAIKRENDTSKLEQLNKEIADLKEEETKQKAQWQSEKEQINKIQQNKIDIENLKFE
ADKAEREGDYGKVAEIRYGKIKQKEEEIREVQAKLKTMQGAAAMIKEEVDSDDIADVVSRWTGIPVSKMMQSEKDKLLRL
ESELHTRVIGQEEAINAIADAVRRSRAGLQDPKRPIGSFIFLGTTGVGKTELAKALAEYLFDDENMMTRIDMSEYQEKFS
ATRLIGAPPGYVGYDEGGQLTEAIRRKPYSVVLFDEIEKAHPDVFNILLQVLDDGRLTDNKGRVVNFKNTIIIMTSNLGS
SLIRENFEKMTPATHDKVVDETKIQVLELLKKTIRPEFLNRIDDIIMFTPLNEEEIRKIVSLQLSSVKKMLATNGVALDF
TNEAVDFIADKGFDPQFGARPVKRVIQKYVLNELSKALLGGTVDRNRPIVIDRKDDGLEFKN

Sequences:

>Translated_862_residues
MNLNNFTIKAQEAVQQAVQLVTKNNQQVIEPVHLLKAVIMTGESVTNFIFQKLGVNAQNLNMVLDRQIESYPKVSGGEPY
LSSESNAVLQKAIDYSSKMGDQYVSLEPIILALFTEKSTASQILKDAGVTEKELRQAIEELRKGNKVTSQSAEETYDALG
KYAINLNERARSGKLDPVIGRDEEIRRVLQILSRRTKNNPILIGEPGVGKTAIAEGLAHRIVRGDVPENLKSKQIFSLDM
GALIAGAKYKGEFEERLKAVVNEVTKSEGEIILFIDEIHTLVGAGKGEGAMDAANILKPALARGELRSIGATTLDEYQKY
FEKDKALERRFQTVIVDEPSELDTISILRGLKEKYENHHKVRIKDDAIISAVQLSTRYITDRFLPDKAIDLMDEAAARLR
LQIDSVPESLDEVSRRIKQLEIEREAIKRENDTSKLEQLNKEIADLKEEETKQKAQWQSEKEQINKIQQNKIDIENLKFE
ADKAEREGDYGKVAEIRYGKIKQKEEEIREVQAKLKTMQGAAAMIKEEVDSDDIADVVSRWTGIPVSKMMQSEKDKLLRL
ESELHTRVIGQEEAINAIADAVRRSRAGLQDPKRPIGSFIFLGTTGVGKTELAKALAEYLFDDENMMTRIDMSEYQEKFS
ATRLIGAPPGYVGYDEGGQLTEAIRRKPYSVVLFDEIEKAHPDVFNILLQVLDDGRLTDNKGRVVNFKNTIIIMTSNLGS
SLIRENFEKMTPATHDKVVDETKIQVLELLKKTIRPEFLNRIDDIIMFTPLNEEEIRKIVSLQLSSVKKMLATNGVALDF
TNEAVDFIADKGFDPQFGARPVKRVIQKYVLNELSKALLGGTVDRNRPIVIDRKDDGLEFKN
>Mature_862_residues
MNLNNFTIKAQEAVQQAVQLVTKNNQQVIEPVHLLKAVIMTGESVTNFIFQKLGVNAQNLNMVLDRQIESYPKVSGGEPY
LSSESNAVLQKAIDYSSKMGDQYVSLEPIILALFTEKSTASQILKDAGVTEKELRQAIEELRKGNKVTSQSAEETYDALG
KYAINLNERARSGKLDPVIGRDEEIRRVLQILSRRTKNNPILIGEPGVGKTAIAEGLAHRIVRGDVPENLKSKQIFSLDM
GALIAGAKYKGEFEERLKAVVNEVTKSEGEIILFIDEIHTLVGAGKGEGAMDAANILKPALARGELRSIGATTLDEYQKY
FEKDKALERRFQTVIVDEPSELDTISILRGLKEKYENHHKVRIKDDAIISAVQLSTRYITDRFLPDKAIDLMDEAAARLR
LQIDSVPESLDEVSRRIKQLEIEREAIKRENDTSKLEQLNKEIADLKEEETKQKAQWQSEKEQINKIQQNKIDIENLKFE
ADKAEREGDYGKVAEIRYGKIKQKEEEIREVQAKLKTMQGAAAMIKEEVDSDDIADVVSRWTGIPVSKMMQSEKDKLLRL
ESELHTRVIGQEEAINAIADAVRRSRAGLQDPKRPIGSFIFLGTTGVGKTELAKALAEYLFDDENMMTRIDMSEYQEKFS
ATRLIGAPPGYVGYDEGGQLTEAIRRKPYSVVLFDEIEKAHPDVFNILLQVLDDGRLTDNKGRVVNFKNTIIIMTSNLGS
SLIRENFEKMTPATHDKVVDETKIQVLELLKKTIRPEFLNRIDDIIMFTPLNEEEIRKIVSLQLSSVKKMLATNGVALDF
TNEAVDFIADKGFDPQFGARPVKRVIQKYVLNELSKALLGGTVDRNRPIVIDRKDDGLEFKN

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=314, Percent_Identity=37.8980891719745, Blast_Score=213, Evalue=5e-55,
Organism=Escherichia coli, GI1788943, Length=862, Percent_Identity=52.3201856148492, Blast_Score=913, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=336, Percent_Identity=46.1309523809524, Blast_Score=291, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6320464, Length=706, Percent_Identity=53.1161473087819, Blast_Score=734, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=852, Percent_Identity=43.3098591549296, Blast_Score=660, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 97062; Mature: 97062

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNNFTIKAQEAVQQAVQLVTKNNQQVIEPVHLLKAVIMTGESVTNFIFQKLGVNAQNL
CCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHH
NMVLDRQIESYPKVSGGEPYLSSESNAVLQKAIDYSSKMGDQYVSLEPIILALFTEKSTA
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHH
SQILKDAGVTEKELRQAIEELRKGNKVTSQSAEETYDALGKYAINLNERARSGKLDPVIG
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEECCCHHHCCCCCCCCCC
RDEEIRRVLQILSRRTKNNPILIGEPGVGKTAIAEGLAHRIVRGDVPENLKSKQIFSLDM
CCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECH
GALIAGAKYKGEFEERLKAVVNEVTKSEGEIILFIDEIHTLVGAGKGEGAMDAANILKPA
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHH
LARGELRSIGATTLDEYQKYFEKDKALERRFQTVIVDEPSELDTISILRGLKEKYENHHK
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCCE
VRIKDDAIISAVQLSTRYITDRFLPDKAIDLMDEAAARLRLQIDSVPESLDEVSRRIKQL
EEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIEREAIKRENDTSKLEQLNKEIADLKEEETKQKAQWQSEKEQINKIQQNKIDIENLKFE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCEEC
ADKAEREGDYGKVAEIRYGKIKQKEEEIREVQAKLKTMQGAAAMIKEEVDSDDIADVVSR
CCHHHCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
WTGIPVSKMMQSEKDKLLRLESELHTRVIGQEEAINAIADAVRRSRAGLQDPKRPIGSFI
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCEE
FLGTTGVGKTELAKALAEYLFDDENMMTRIDMSEYQEKFSATRLIGAPPGYVGYDEGGQL
EEECCCCCHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
TEAIRRKPYSVVLFDEIEKAHPDVFNILLQVLDDGRLTDNKGRVVNFKNTIIIMTSNLGS
HHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCEECCCCCEEEECCEEEEEECCCCH
SLIRENFEKMTPATHDKVVDETKIQVLELLKKTIRPEFLNRIDDIIMFTPLNEEEIRKIV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHEEEECCCCHHHHHHHH
SLQLSSVKKMLATNGVALDFTNEAVDFIADKGFDPQFGARPVKRVIQKYVLNELSKALLG
HHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GTVDRNRPIVIDRKDDGLEFKN
CCCCCCCCEEEECCCCCCCCCC
>Mature Secondary Structure
MNLNNFTIKAQEAVQQAVQLVTKNNQQVIEPVHLLKAVIMTGESVTNFIFQKLGVNAQNL
CCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHH
NMVLDRQIESYPKVSGGEPYLSSESNAVLQKAIDYSSKMGDQYVSLEPIILALFTEKSTA
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHH
SQILKDAGVTEKELRQAIEELRKGNKVTSQSAEETYDALGKYAINLNERARSGKLDPVIG
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEECCCHHHCCCCCCCCCC
RDEEIRRVLQILSRRTKNNPILIGEPGVGKTAIAEGLAHRIVRGDVPENLKSKQIFSLDM
CCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECH
GALIAGAKYKGEFEERLKAVVNEVTKSEGEIILFIDEIHTLVGAGKGEGAMDAANILKPA
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHH
LARGELRSIGATTLDEYQKYFEKDKALERRFQTVIVDEPSELDTISILRGLKEKYENHHK
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCCE
VRIKDDAIISAVQLSTRYITDRFLPDKAIDLMDEAAARLRLQIDSVPESLDEVSRRIKQL
EEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIEREAIKRENDTSKLEQLNKEIADLKEEETKQKAQWQSEKEQINKIQQNKIDIENLKFE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCEEC
ADKAEREGDYGKVAEIRYGKIKQKEEEIREVQAKLKTMQGAAAMIKEEVDSDDIADVVSR
CCHHHCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
WTGIPVSKMMQSEKDKLLRLESELHTRVIGQEEAINAIADAVRRSRAGLQDPKRPIGSFI
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCEE
FLGTTGVGKTELAKALAEYLFDDENMMTRIDMSEYQEKFSATRLIGAPPGYVGYDEGGQL
EEECCCCCHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
TEAIRRKPYSVVLFDEIEKAHPDVFNILLQVLDDGRLTDNKGRVVNFKNTIIIMTSNLGS
HHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCEECCCCCEEEECCEEEEEECCCCH
SLIRENFEKMTPATHDKVVDETKIQVLELLKKTIRPEFLNRIDDIIMFTPLNEEEIRKIV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHEEEECCCCHHHHHHHH
SLQLSSVKKMLATNGVALDFTNEAVDFIADKGFDPQFGARPVKRVIQKYVLNELSKALLG
HHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GTVDRNRPIVIDRKDDGLEFKN
CCCCCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]