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The map label for this gene is pabB [C]

Identifier: 150007816

GI number: 150007816

Start: 1368399

End: 1369406

Strand: Reverse

Name: pabB [C]

Synonym: BDI_1174

Alternate gene names: 150007816

Gene position: 1369406-1368399 (Counterclockwise)

Preceding gene: 150007817

Following gene: 150007815

Centisome position: 28.46

GC content: 49.11

Gene sequence:

>1008_bases
ATGACCGAATACACGCAAGAAGAGGCCATCTTCCGCATGAACGAAATGGGGAAAGCGGGACGGCCTTTCCTTTTTATCAT
TGATTATAAACGAGAGCGGATCTACGTGGAGAGTCCGGAAGAGATCGCTCCCTCCGAGTTATTGTACGATTTGAACGGCT
TTACGAATATAAATCACGAATGTAACTTGCGGGATTCCTCTCATCTTATATCCGGAGAACCTGTTGAATGGCAACCCTCG
TATGTTTCTTTCGAGGAGTATGTCCATTCATTCGAGACCGTTTCCCGGCATATCCATGCGGGTAATTCTTATTTGGTAAA
CTTGACATGCGCTACTCCGGTATATACGAACCTCTCCTTGAAAGATATCTTTTACCATTCCAAGGCGATGTATAAGCTTT
GGATGCGGGATCGTTTCGTGGTATTCTCGCCCGAGATATTCGTGCGGACGCGGGATGGTCTCATCTATTCGTATCCCATG
AAAGGTACGATTGACGCTACGCTGCCCGATGCCCGGAGACGTATCCTCGATGATCCCAAGGAAGCGGCGGAGCATGCCAC
GATCGTGGATTTGATCCGGAATGACTTGAGTATCCTAGCCTCCGAGGTTTGTGTTCCCCGGTATCGTTATATCGATGAAT
TGCGTACGCATAACGGAAGTTTGTTGCAGGTCAGCTCTGAGATAAGAGGCCGGTTGCCGGAGGGATGGAACGGACATGTC
GGGGAGATTTTGTTCAGCCTCTTGCCTGCCGGCTCCATCACGGGCGCTCCCAAGAAAAAGACCTTGGAGATCATCGCCGA
GGCGGAAACCTATGAGCGGGGCTTCTATACGGGGGTGATGGGGTATTTTGACGGCCAAGATTTAGACAGCGCCGTGATGA
TCCGTTTTATGGAACAAGTCTCTCCCCGTTCGTTTGTTTTCAAGAGCGGTGGGGGAATCACCTCTAAAAGTGATGTGAGA
TCGGAGTATAACGAGATGAAACAAAAAGTATATGTGCCCATCTATTGA

Upstream 100 bases:

>100_bases
TCGACAAGACTCGCGGTGAGAACGTGCGTCGTTGGTGGCCTTTCTTCCGGGATCGCCGTATCGATGCGTTTGGTGGTTTG
ACAGAACGATTTTTAGTATA

Downstream 100 bases:

>100_bases
GACCTTATCAGGGAGTCCGTTTGTGGAGACGATCCGTATCGAGAGGGGACGGATACATAACCTTCCGTACCATAATGCCC
GTATGAACCGTACCCGCAGG

Product: para-aminobenzoate synthase component I

Products: 4-amino-4-deoxychorismate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTEYTQEEAIFRMNEMGKAGRPFLFIIDYKRERIYVESPEEIAPSELLYDLNGFTNINHECNLRDSSHLISGEPVEWQPS
YVSFEEYVHSFETVSRHIHAGNSYLVNLTCATPVYTNLSLKDIFYHSKAMYKLWMRDRFVVFSPEIFVRTRDGLIYSYPM
KGTIDATLPDARRRILDDPKEAAEHATIVDLIRNDLSILASEVCVPRYRYIDELRTHNGSLLQVSSEIRGRLPEGWNGHV
GEILFSLLPAGSITGAPKKKTLEIIAEAETYERGFYTGVMGYFDGQDLDSAVMIRFMEQVSPRSFVFKSGGGITSKSDVR
SEYNEMKQKVYVPIY

Sequences:

>Translated_335_residues
MTEYTQEEAIFRMNEMGKAGRPFLFIIDYKRERIYVESPEEIAPSELLYDLNGFTNINHECNLRDSSHLISGEPVEWQPS
YVSFEEYVHSFETVSRHIHAGNSYLVNLTCATPVYTNLSLKDIFYHSKAMYKLWMRDRFVVFSPEIFVRTRDGLIYSYPM
KGTIDATLPDARRRILDDPKEAAEHATIVDLIRNDLSILASEVCVPRYRYIDELRTHNGSLLQVSSEIRGRLPEGWNGHV
GEILFSLLPAGSITGAPKKKTLEIIAEAETYERGFYTGVMGYFDGQDLDSAVMIRFMEQVSPRSFVFKSGGGITSKSDVR
SEYNEMKQKVYVPIY
>Mature_334_residues
TEYTQEEAIFRMNEMGKAGRPFLFIIDYKRERIYVESPEEIAPSELLYDLNGFTNINHECNLRDSSHLISGEPVEWQPSY
VSFEEYVHSFETVSRHIHAGNSYLVNLTCATPVYTNLSLKDIFYHSKAMYKLWMRDRFVVFSPEIFVRTRDGLIYSYPMK
GTIDATLPDARRRILDDPKEAAEHATIVDLIRNDLSILASEVCVPRYRYIDELRTHNGSLLQVSSEIRGRLPEGWNGHVG
EILFSLLPAGSITGAPKKKTLEIIAEAETYERGFYTGVMGYFDGQDLDSAVMIRFMEQVSPRSFVFKSGGGITSKSDVRS
EYNEMKQKVYVPIY

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To the C-terminal of para-aminobenzoate synthase component I [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=274, Percent_Identity=30.6569343065693, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787518, Length=278, Percent_Identity=29.4964028776978, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320935, Length=274, Percent_Identity=28.8321167883212, Blast_Score=90, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324361, Length=285, Percent_Identity=28.0701754385965, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR015890 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: 6.3.5.8

Molecular weight: Translated: 38475; Mature: 38344

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEYTQEEAIFRMNEMGKAGRPFLFIIDYKRERIYVESPEEIAPSELLYDLNGFTNINHE
CCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCEEEECCCCCCCHHHHHHHCCCCCCCCCE
CNLRDSSHLISGEPVEWQPSYVSFEEYVHSFETVSRHIHAGNSYLVNLTCATPVYTNLSL
ECCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEECCCCH
KDIFYHSKAMYKLWMRDRFVVFSPEIFVRTRDGLIYSYPMKGTIDATLPDARRRILDDPK
HHHHHHHHHHHHHHHHCEEEEECCEEEEEECCCEEEECCCCCCCCCCCCHHHHHHHCCHH
EAAEHATIVDLIRNDLSILASEVCVPRYRYIDELRTHNGSLLQVSSEIRGRLPEGWNGHV
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEEECHHHCCCCCCCCCCCH
GEILFSLLPAGSITGAPKKKTLEIIAEAETYERGFYTGVMGYFDGQDLDSAVMIRFMEQV
HHHHHHHCCCCCCCCCCCHHHHHEEEHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHC
SPRSFVFKSGGGITSKSDVRSEYNEMKQKVYVPIY
CCCEEEEECCCCCCCHHHHHHHHHHHHHEEECCCC
>Mature Secondary Structure 
TEYTQEEAIFRMNEMGKAGRPFLFIIDYKRERIYVESPEEIAPSELLYDLNGFTNINHE
CCCCHHHHHHHHHHCCCCCCCEEEEEEECCCEEEECCCCCCCHHHHHHHCCCCCCCCCE
CNLRDSSHLISGEPVEWQPSYVSFEEYVHSFETVSRHIHAGNSYLVNLTCATPVYTNLSL
ECCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEECCCCH
KDIFYHSKAMYKLWMRDRFVVFSPEIFVRTRDGLIYSYPMKGTIDATLPDARRRILDDPK
HHHHHHHHHHHHHHHHCEEEEECCEEEEEECCCEEEECCCCCCCCCCCCHHHHHHHCCHH
EAAEHATIVDLIRNDLSILASEVCVPRYRYIDELRTHNGSLLQVSSEIRGRLPEGWNGHV
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEEECHHHCCCCCCCCCCCH
GEILFSLLPAGSITGAPKKKTLEIIAEAETYERGFYTGVMGYFDGQDLDSAVMIRFMEQV
HHHHHHHCCCCCCCCCCCHHHHHEEEHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHC
SPRSFVFKSGGGITSKSDVRSEYNEMKQKVYVPIY
CCCEEEEECCCCCCCHHHHHHHHHHHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: chorismate; L-glutamine

Specific reaction: chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate

General reaction: Lyases; Carbon-Carbon Lyases; Oxo-Acid-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]