Click here to switch to the map view.

The map label for this gene is menB [H]

Identifier: 150007779

GI number: 150007779

Start: 1312688

End: 1313512

Strand: Direct

Name: menB [H]

Synonym: BDI_1137

Alternate gene names: 150007779

Gene position: 1312688-1313512 (Clockwise)

Preceding gene: 150007778

Following gene: 150007780

Centisome position: 27.28

GC content: 54.55

Gene sequence:

>825_bases
ATGGAAACGAAAAGAGAATGGACAACCATCAAGGAATACGAGGAGATCTTATTTGATTTCTACAACGGCATCGCCCGCAT
TACGATAAACCGGGAACGGTATCGCAACGCTTTTACCCCGACTACGACCACGGAGATGAGCGACGCCTTTTACATCTGCC
GGGAACGTCCGGACATTAACGTAGTCGTTCTGACAGGAGCCGGAGATACGGCGTTTTGCGCGGGAGGCGATATGAACGTG
AAAGGACGTGGCGGCTACGTGGGTAAAGACGGCGTACCTCGCTTGAACGTATTGGACGTACAAAAGCAGATCCGCTCTCT
CCCGAAACCCGTCATCGCGGCCGTGAACGGTTTCGCTATCGGCGGCGGACACGTATTGCACGTGGTTTGCGACCTTACGA
TCGCTTCCGAGAACGCTATCTTCGGACAGACAGGCCCTCGTGTGGGTAGCTTCGACGCCGGGTTCGGCTCTTCTTACCTC
GCCCGTGTGGTCGGACAGAAAAAGGCCCGTGAGATCTGGTTCCTATGCCGCAAGTACAATGCACAGGAGGCTTTGGATAT
GGGTCTGGTAAATAAGGTAGTCCCCTTGGATAAATTAGAGGACGAGTACGTTCAATGGGCCGAGGAGATGATGTTGCTTA
GCCCGTTGGCTTTGCGCATGATCAAGGCGGGCTTAAACGCCGAGTTGGACGGACAGGCCGGTATACAGGAGTTGGCCGGA
GACGCTACCATGCTTTACTATATGACGGACGAGGCGCAGGAAGGCGGTAAGGCATTCTTGGAGAAACGCCGTCCCCGCTT
CGAGGATTACCCGAAGTTCCCGTAA

Upstream 100 bases:

>100_bases
ATTCATGGAGGTTTTCACGGACAAAGCGGAAGACGTACGATTGCTCAAGGAATATTATCATCAACTAAAAAATTCATCCC
AAGCACAAAACATATAATAT

Downstream 100 bases:

>100_bases
AGGGAATTGAGAATTGAGAATTGAGAATTGAAAATTGAAAATGAATGGTGAAGGAGAGGTTTTATAAGACAGAGGTGGTT
CCCCGGTGCTTGACTTTCAA

Product: naphthoate synthase

Products: NA

Alternate protein names: DHNA-CoA synthase [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
METKREWTTIKEYEEILFDFYNGIARITINRERYRNAFTPTTTTEMSDAFYICRERPDINVVVLTGAGDTAFCAGGDMNV
KGRGGYVGKDGVPRLNVLDVQKQIRSLPKPVIAAVNGFAIGGGHVLHVVCDLTIASENAIFGQTGPRVGSFDAGFGSSYL
ARVVGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLDKLEDEYVQWAEEMMLLSPLALRMIKAGLNAELDGQAGIQELAG
DATMLYYMTDEAQEGGKAFLEKRRPRFEDYPKFP

Sequences:

>Translated_274_residues
METKREWTTIKEYEEILFDFYNGIARITINRERYRNAFTPTTTTEMSDAFYICRERPDINVVVLTGAGDTAFCAGGDMNV
KGRGGYVGKDGVPRLNVLDVQKQIRSLPKPVIAAVNGFAIGGGHVLHVVCDLTIASENAIFGQTGPRVGSFDAGFGSSYL
ARVVGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLDKLEDEYVQWAEEMMLLSPLALRMIKAGLNAELDGQAGIQELAG
DATMLYYMTDEAQEGGKAFLEKRRPRFEDYPKFP
>Mature_274_residues
METKREWTTIKEYEEILFDFYNGIARITINRERYRNAFTPTTTTEMSDAFYICRERPDINVVVLTGAGDTAFCAGGDMNV
KGRGGYVGKDGVPRLNVLDVQKQIRSLPKPVIAAVNGFAIGGGHVLHVVCDLTIASENAIFGQTGPRVGSFDAGFGSSYL
ARVVGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLDKLEDEYVQWAEEMMLLSPLALRMIKAGLNAELDGQAGIQELAG
DATMLYYMTDEAQEGGKAFLEKRRPRFEDYPKFP

Specific function: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) (Probable) [H]

COG id: COG0447

COG function: function code H; Dihydroxynaphthoic acid synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=255, Percent_Identity=33.7254901960784, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI31542718, Length=262, Percent_Identity=30.5343511450382, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4502327, Length=260, Percent_Identity=28.0769230769231, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI70995211, Length=220, Percent_Identity=32.7272727272727, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI116235487, Length=215, Percent_Identity=27.906976744186, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI45643119, Length=213, Percent_Identity=27.6995305164319, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI260275230, Length=213, Percent_Identity=27.6995305164319, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI260274832, Length=213, Percent_Identity=27.6995305164319, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI37594471, Length=155, Percent_Identity=27.0967741935484, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI37594469, Length=155, Percent_Identity=27.0967741935484, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4757966, Length=221, Percent_Identity=27.1493212669683, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI51538581, Length=221, Percent_Identity=27.1493212669683, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI25453481, Length=221, Percent_Identity=27.1493212669683, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI51538573, Length=221, Percent_Identity=27.1493212669683, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788597, Length=272, Percent_Identity=61.3970588235294, Blast_Score=343, Evalue=8e-96,
Organism=Escherichia coli, GI1787659, Length=261, Percent_Identity=32.5670498084291, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI221142681, Length=247, Percent_Identity=30.7692307692308, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87082183, Length=252, Percent_Identity=30.1587301587302, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787660, Length=267, Percent_Identity=29.9625468164794, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788682, Length=202, Percent_Identity=26.7326732673267, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790281, Length=180, Percent_Identity=27.2222222222222, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17554946, Length=249, Percent_Identity=32.9317269076305, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI25145438, Length=246, Percent_Identity=33.739837398374, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17540714, Length=205, Percent_Identity=29.7560975609756, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17560910, Length=181, Percent_Identity=34.2541436464088, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17549921, Length=215, Percent_Identity=26.9767441860465, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17535521, Length=246, Percent_Identity=25.2032520325203, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=253, Percent_Identity=26.4822134387352, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17536985, Length=262, Percent_Identity=25.5725190839695, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20129971, Length=269, Percent_Identity=33.0855018587361, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24653477, Length=269, Percent_Identity=33.0855018587361, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24653139, Length=256, Percent_Identity=30.46875, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI19922422, Length=254, Percent_Identity=25.9842519685039, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357171, Length=184, Percent_Identity=32.0652173913043, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI19920382, Length=262, Percent_Identity=28.6259541984733, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24650670, Length=179, Percent_Identity=30.7262569832402, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24654903, Length=202, Percent_Identity=27.7227722772277, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR010198 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.1.3.36 [H]

Molecular weight: Translated: 30529; Mature: 30529

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKREWTTIKEYEEILFDFYNGIARITINRERYRNAFTPTTTTEMSDAFYICRERPDIN
CCCCHHHHHHHHHHHHHHHHHCCEEEEEECHHHHCCCCCCCCCCCCCCCEEEEECCCCCE
VVVLTGAGDTAFCAGGDMNVKGRGGYVGKDGVPRLNVLDVQKQIRSLPKPVIAAVNGFAI
EEEEECCCCEEEECCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCEEE
GGGHVLHVVCDLTIASENAIFGQTGPRVGSFDAGFGSSYLARVVGQKKAREIWFLCRKYN
CCCCEEEEEEEEEECCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
AQEALDMGLVNKVVPLDKLEDEYVQWAEEMMLLSPLALRMIKAGLNAELDGQAGIQELAG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCC
DATMLYYMTDEAQEGGKAFLEKRRPRFEDYPKFP
CCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
METKREWTTIKEYEEILFDFYNGIARITINRERYRNAFTPTTTTEMSDAFYICRERPDIN
CCCCHHHHHHHHHHHHHHHHHCCEEEEEECHHHHCCCCCCCCCCCCCCCEEEEECCCCCE
VVVLTGAGDTAFCAGGDMNVKGRGGYVGKDGVPRLNVLDVQKQIRSLPKPVIAAVNGFAI
EEEEECCCCEEEECCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCEEE
GGGHVLHVVCDLTIASENAIFGQTGPRVGSFDAGFGSSYLARVVGQKKAREIWFLCRKYN
CCCCEEEEEEEEEECCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
AQEALDMGLVNKVVPLDKLEDEYVQWAEEMMLLSPLALRMIKAGLNAELDGQAGIQELAG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCC
DATMLYYMTDEAQEGGKAFLEKRRPRFEDYPKFP
CCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA