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The map label for this gene is serB [H]

Identifier: 150007749

GI number: 150007749

Start: 1283157

End: 1284383

Strand: Direct

Name: serB [H]

Synonym: BDI_1107

Alternate gene names: 150007749

Gene position: 1283157-1284383 (Clockwise)

Preceding gene: 150007747

Following gene: 150007750

Centisome position: 26.67

GC content: 47.03

Gene sequence:

>1227_bases
ATGGCACAAAACGACGAAATAATACTGATAAATATCAATGGAGCGGATCGTCCGGGTGTAACGGCGGCTCTTACGGAGAT
TCTAGCCAAGAACAACGCTGTTATCCTCGATATCGGTCAAGCGGATATCCATAACCATTTATCATTGGGTATCTTGTTTC
AAAGCACGGAAGGAAATTCCGGCGATATATTGAAAGAACTACTGTTCAAGAGTTACGAATTAGACGTCAATATCCGTTTC
AATCCCATTACAGAGCAAGAATATAGTAAATGGGTAGGTATGCAGGGCAAGAACCGATATATCATCACGATATTAAGCCG
AAAGCTTACAGCCAAGCAAATCGCGGGTGTTTCCCGGATCGTAGCGGAGCAAGATATGAATATTGATGATATCAAGCGGC
TCACGGGACGTATCCCGTTGGACGAGAATGCCCGTACCCCCAAGGCGAGCGTGGAGTTTTCCGTACGTGGTACCCCGAAA
AACAAGGAGTGCATGAAAGCGGAGTTCATGAAACTTTCCACGGAGCTTGAGATGGATATCTCTTTCCAAGAGGATAGCAT
GTATCGCCGTATGCGCCGTCTGATTTGTTTCGATATGGACTCTACCTTGATAGAGACGGAGGTTATCGACGAGTTGGCGA
TACGTGCCGGAGTTGGCGATCAAGTAAAAGCGATTACAGAGGCAGCCATGCGTGGAGAGATCGATTTCTGCGAGAGCTTC
CGCCAGCGTTGTGCCTTATTAAAGGGGTTGGACGTATCCGTGATGCAGGAGATCGCCGAGAATCTACCGATCACAGAAGG
TGTAGACCGTTTGATGCGTATCTTGAAAAAGGTGGGCTTCAAGATCGCTATCCTTTCCGGAGGTTTCACTTATTTCGGTA
ATTTCCTTAAACAAAAATATAATATCGACTATGTATACGCCAACGAGCTTGAGATCGAGAATGGCAAGCTAACGGGTAAT
CATGTGGGCGATATCGTAGATGGGAAGCGGAAAGCGGAATTATTACGCCTGATCGCGCAAGTGGAGAACGTGGATATTCG
CCAGACCGTAGCGGTTGGCGACGGGGCGAACGACTTGCCGATGATTAGTATCGCCGGTCTAGGTATCGCCTTCCATGCCA
AACCGAAGGTAAAGGCGACCGCCAAGCAATCTATCTCTACGATTGGCCTCGATGGTATCTTATATTTCCTTGGATACAAG
GATTCGTATTTGGATGAACAGATGTAA

Upstream 100 bases:

>100_bases
TTGTCGTTAATACGATAAAACAAATATAAGCAAAAATGTTTAATATATTATACTCTTTTTCGATAATTCTTACGTACTTT
TGCCTAATAGAATGACAAAT

Downstream 100 bases:

>100_bases
TATATATAATTAATGTATAGCGATTATGATCAGACATATTGTAATGTTTAAGTTGAAGGAGTTTCAAACTCCGGCTGAGA
AGCAAGCCAAAATGCAAGAA

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MAQNDEIILININGADRPGVTAALTEILAKNNAVILDIGQADIHNHLSLGILFQSTEGNSGDILKELLFKSYELDVNIRF
NPITEQEYSKWVGMQGKNRYIITILSRKLTAKQIAGVSRIVAEQDMNIDDIKRLTGRIPLDENARTPKASVEFSVRGTPK
NKECMKAEFMKLSTELEMDISFQEDSMYRRMRRLICFDMDSTLIETEVIDELAIRAGVGDQVKAITEAAMRGEIDFCESF
RQRCALLKGLDVSVMQEIAENLPITEGVDRLMRILKKVGFKIAILSGGFTYFGNFLKQKYNIDYVYANELEIENGKLTGN
HVGDIVDGKRKAELLRLIAQVENVDIRQTVAVGDGANDLPMISIAGLGIAFHAKPKVKATAKQSISTIGLDGILYFLGYK
DSYLDEQM

Sequences:

>Translated_408_residues
MAQNDEIILININGADRPGVTAALTEILAKNNAVILDIGQADIHNHLSLGILFQSTEGNSGDILKELLFKSYELDVNIRF
NPITEQEYSKWVGMQGKNRYIITILSRKLTAKQIAGVSRIVAEQDMNIDDIKRLTGRIPLDENARTPKASVEFSVRGTPK
NKECMKAEFMKLSTELEMDISFQEDSMYRRMRRLICFDMDSTLIETEVIDELAIRAGVGDQVKAITEAAMRGEIDFCESF
RQRCALLKGLDVSVMQEIAENLPITEGVDRLMRILKKVGFKIAILSGGFTYFGNFLKQKYNIDYVYANELEIENGKLTGN
HVGDIVDGKRKAELLRLIAQVENVDIRQTVAVGDGANDLPMISIAGLGIAFHAKPKVKATAKQSISTIGLDGILYFLGYK
DSYLDEQM
>Mature_407_residues
AQNDEIILININGADRPGVTAALTEILAKNNAVILDIGQADIHNHLSLGILFQSTEGNSGDILKELLFKSYELDVNIRFN
PITEQEYSKWVGMQGKNRYIITILSRKLTAKQIAGVSRIVAEQDMNIDDIKRLTGRIPLDENARTPKASVEFSVRGTPKN
KECMKAEFMKLSTELEMDISFQEDSMYRRMRRLICFDMDSTLIETEVIDELAIRAGVGDQVKAITEAAMRGEIDFCESFR
QRCALLKGLDVSVMQEIAENLPITEGVDRLMRILKKVGFKIAILSGGFTYFGNFLKQKYNIDYVYANELEIENGKLTGNH
VGDIVDGKRKAELLRLIAQVENVDIRQTVAVGDGANDLPMISIAGLGIAFHAKPKVKATAKQSISTIGLDGILYFLGYKD
SYLDEQM

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=200, Percent_Identity=32, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1790849, Length=233, Percent_Identity=47.6394849785408, Blast_Score=219, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI115534454, Length=228, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115534456, Length=228, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115534458, Length=236, Percent_Identity=30.0847457627119, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=311, Percent_Identity=38.5852090032154, Blast_Score=200, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24661601, Length=207, Percent_Identity=29.951690821256, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 45543; Mature: 45412

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQNDEIILININGADRPGVTAALTEILAKNNAVILDIGQADIHNHLSLGILFQSTEGNS
CCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCHHHCCCEEEEEEEEECCCCC
GDILKELLFKSYELDVNIRFNPITEQEYSKWVGMQGKNRYIITILSRKLTAKQIAGVSRI
HHHHHHHHHHHEEEEEEEEECCCCHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHH
VAEQDMNIDDIKRLTGRIPLDENARTPKASVEFSVRGTPKNKECMKAEFMKLSTELEMDI
HHHCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCEEEEE
SFQEDSMYRRMRRLICFDMDSTLIETEVIDELAIRAGVGDQVKAITEAAMRGEIDFCESF
EECHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHH
RQRCALLKGLDVSVMQEIAENLPITEGVDRLMRILKKVGFKIAILSGGFTYFGNFLKQKY
HHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHC
NIDYVYANELEIENGKLTGNHVGDIVDGKRKAELLRLIAQVENVDIRQTVAVGDGANDLP
CCEEEEECEEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCC
MISIAGLGIAFHAKPKVKATAKQSISTIGLDGILYFLGYKDSYLDEQM
EEEEECCCEEEECCCCCHHHHHHHHHHCCHHHEEEEECCCHHHHCCCC
>Mature Secondary Structure 
AQNDEIILININGADRPGVTAALTEILAKNNAVILDIGQADIHNHLSLGILFQSTEGNS
CCCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCHHHCCCEEEEEEEEECCCCC
GDILKELLFKSYELDVNIRFNPITEQEYSKWVGMQGKNRYIITILSRKLTAKQIAGVSRI
HHHHHHHHHHHEEEEEEEEECCCCHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHH
VAEQDMNIDDIKRLTGRIPLDENARTPKASVEFSVRGTPKNKECMKAEFMKLSTELEMDI
HHHCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCEEEEE
SFQEDSMYRRMRRLICFDMDSTLIETEVIDELAIRAGVGDQVKAITEAAMRGEIDFCESF
EECHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHH
RQRCALLKGLDVSVMQEIAENLPITEGVDRLMRILKKVGFKIAILSGGFTYFGNFLKQKY
HHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHC
NIDYVYANELEIENGKLTGNHVGDIVDGKRKAELLRLIAQVENVDIRQTVAVGDGANDLP
CCEEEEECEEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCC
MISIAGLGIAFHAKPKVKATAKQSISTIGLDGILYFLGYKDSYLDEQM
EEEEECCCEEEECCCCCHHHHHHHHHHCCHHHEEEEECCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA