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The map label for this gene is cbiHC [H]

Identifier: 150007712

GI number: 150007712

Start: 1238811

End: 1240223

Strand: Reverse

Name: cbiHC [H]

Synonym: BDI_1067

Alternate gene names: 150007712

Gene position: 1240223-1238811 (Counterclockwise)

Preceding gene: 150007713

Following gene: 150007711

Centisome position: 25.78

GC content: 48.55

Gene sequence:

>1413_bases
ATGAATAAAGGCAAGATTATAGTCGCCGGAATCGGCCCCGGTAGCGAGGCCGATATAACGCCTGCGGTTTTGGCCGCTAT
CCAAAGCTCGGATGTCATCATAGGATATAAATATTATTTCCGTTTTATCACCCACTTGCTTCGTGAGGGAACGGAATGTA
TAGATACAGGTATGAAACGTGAGCAAGCTCGTGCCGAGCAAGCTTTCGCTTATGCCAACGAGGGAAAGACGGTTTGCGTG
ATCAGTTCCGGTGACGCCGGTATTTATGGCATGACTCCTCTGATTTATGAGATGAAGAAAGAATCCGGAAGCGAGATCGA
GATCGAGTCGTATCCGGGCATCAGCGCTTTCCAGAAAGCTGCGTCCTTGCTTGGCGCTCCTATCGGACATGATTTCTGTG
TGATTTCCCTCTCAGACTTGATGACTCCTTGGGAACTGATCGAGAAACGGATTCACGCGGCGGCCATGGCCGATTTTGTT
ACGGCGATCTATAATCCAAAAAGCGAGGGACGTTATTGGCAACTCTATCGCTTAAAAGAATTGTTCCTGCAAGAACGCAA
GCCGGAGACTCCGGTCGGTTATGTACGTCAGGCCGGACGGGAGGAGCAAGAAGTATTCGTCACTACGCTCGCAGATCTGG
ACCCCGAGCAGATCGATATGTTTACGGTAGTCTTGATCGGAAACTCACAAACATATCTTTCCGGGAATCATATGATCACT
CCCCGGGGATATTATGGCGAGATCAAACAAAAGAAAATGGATACGGGTATCGGACAGGACATCATGATCCGTAGTTTCCG
TACGATCGAGAAGGAATTGAAAAACCAAGAGATCCCGTTGGATAAGAAATGGGCGTTACTCCATGCCATTCATACGACGG
CCGATTTCGATATGGAAAATATCCTTTATGCCGACCCGGATGCTGTCTCTACATTATATAATAAGATCAGCGGCGGGGAA
GTTCCTACGATCATCACCGATGTCACGATGGCTGCTTCCGGCATTCGTAAGGGAGCTCTGCAACGTCTGGGTGTCGAAGT
GAAATGTTATCTTCAAGACGAGCGGGTCGCTGAGATGGCTTCGAGCAAAGGAATTACCCGTACCCAAGCCGGTATTCGTC
GGGCCGTGGAAGAGCATCCGACCGCTCTGTTTGTCTTCGGGAACGCCCCGACCGCCCTTATGGAATTATGCGATTTAATA
CGTAAAGGTAAAGCCACTCCAGCTGGCATTATCGCGGCTCCGGTAGGTTTTGTACATGTGCAGGAATCCAAACATATGGT
GAAACCTTTTATCGGTATACCGAAACTAATCGTGGAAGGTCGTAAAGGAGGTAGTAATTTAGCGGCTACGCTAGTGAATG
CCATCCTTTGTTTTAATGACGCAGAACAATTAAAGCCGGGAAGAGATGTATGA

Upstream 100 bases:

>100_bases
TTGCGATAAAATATATCAGGCGAAAAGCGAGAAGAAAGAAGTAAAGCCTGTATATTTGTATTATATTTATTGAGAACATT
GTATTATAAAATAGATTTGA

Downstream 100 bases:

>100_bases
ACCGATTTTATGTCATAGGGCTGGATGATAATATGCGGCAATACTTTCCGCCGGAGATATTGGAGATAATCTCGTCCCAC
CGGGTGTTCTCCGGAGGCGT

Product: precorrin-3B C17-methyltransferase

Products: NA

Alternate protein names: Cobalt-precorrin-3B C(17)-methyltransferase; Cobalt-precorrin-3 methylase; Cobalt-precorrin-3 methyltransferase; Cobalt-precorrin-8X methylmutase; Cobalt-precorrin isomerase [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MNKGKIIVAGIGPGSEADITPAVLAAIQSSDVIIGYKYYFRFITHLLREGTECIDTGMKREQARAEQAFAYANEGKTVCV
ISSGDAGIYGMTPLIYEMKKESGSEIEIESYPGISAFQKAASLLGAPIGHDFCVISLSDLMTPWELIEKRIHAAAMADFV
TAIYNPKSEGRYWQLYRLKELFLQERKPETPVGYVRQAGREEQEVFVTTLADLDPEQIDMFTVVLIGNSQTYLSGNHMIT
PRGYYGEIKQKKMDTGIGQDIMIRSFRTIEKELKNQEIPLDKKWALLHAIHTTADFDMENILYADPDAVSTLYNKISGGE
VPTIITDVTMAASGIRKGALQRLGVEVKCYLQDERVAEMASSKGITRTQAGIRRAVEEHPTALFVFGNAPTALMELCDLI
RKGKATPAGIIAAPVGFVHVQESKHMVKPFIGIPKLIVEGRKGGSNLAATLVNAILCFNDAEQLKPGRDV

Sequences:

>Translated_470_residues
MNKGKIIVAGIGPGSEADITPAVLAAIQSSDVIIGYKYYFRFITHLLREGTECIDTGMKREQARAEQAFAYANEGKTVCV
ISSGDAGIYGMTPLIYEMKKESGSEIEIESYPGISAFQKAASLLGAPIGHDFCVISLSDLMTPWELIEKRIHAAAMADFV
TAIYNPKSEGRYWQLYRLKELFLQERKPETPVGYVRQAGREEQEVFVTTLADLDPEQIDMFTVVLIGNSQTYLSGNHMIT
PRGYYGEIKQKKMDTGIGQDIMIRSFRTIEKELKNQEIPLDKKWALLHAIHTTADFDMENILYADPDAVSTLYNKISGGE
VPTIITDVTMAASGIRKGALQRLGVEVKCYLQDERVAEMASSKGITRTQAGIRRAVEEHPTALFVFGNAPTALMELCDLI
RKGKATPAGIIAAPVGFVHVQESKHMVKPFIGIPKLIVEGRKGGSNLAATLVNAILCFNDAEQLKPGRDV
>Mature_470_residues
MNKGKIIVAGIGPGSEADITPAVLAAIQSSDVIIGYKYYFRFITHLLREGTECIDTGMKREQARAEQAFAYANEGKTVCV
ISSGDAGIYGMTPLIYEMKKESGSEIEIESYPGISAFQKAASLLGAPIGHDFCVISLSDLMTPWELIEKRIHAAAMADFV
TAIYNPKSEGRYWQLYRLKELFLQERKPETPVGYVRQAGREEQEVFVTTLADLDPEQIDMFTVVLIGNSQTYLSGNHMIT
PRGYYGEIKQKKMDTGIGQDIMIRSFRTIEKELKNQEIPLDKKWALLHAIHTTADFDMENILYADPDAVSTLYNKISGGE
VPTIITDVTMAASGIRKGALQRLGVEVKCYLQDERVAEMASSKGITRTQAGIRRAVEEHPTALFVFGNAPTALMELCDLI
RKGKATPAGIIAAPVGFVHVQESKHMVKPFIGIPKLIVEGRKGGSNLAATLVNAILCFNDAEQLKPGRDV

Specific function: Bifunctional enzyme with a methyltransferase domain that catalyzes the methylation of C-17 in cobalt-precorrin-3B to form cobalt-precorrin-4 and an isomerase domain that catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration

COG id: COG1010

COG function: function code H; Precorrin-3B methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014422
- InterPro:   IPR003722
- InterPro:   IPR006363 [H]

Pfam domain/function: PF02570 CbiC; PF00590 TP_methylase [H]

EC number: NA

Molecular weight: Translated: 51733; Mature: 51733

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKGKIIVAGIGPGSEADITPAVLAAIQSSDVIIGYKYYFRFITHLLREGTECIDTGMKR
CCCCCEEEEECCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCHHHHHHCHHH
EQARAEQAFAYANEGKTVCVISSGDAGIYGMTPLIYEMKKESGSEIEIESYPGISAFQKA
HHHHHHHHHHEECCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCEEEEECCCCHHHHHHH
ASLLGAPIGHDFCVISLSDLMTPWELIEKRIHAAAMADFVTAIYNPKSEGRYWQLYRLKE
HHHHCCCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHH
LFLQERKPETPVGYVRQAGREEQEVFVTTLADLDPEQIDMFTVVLIGNSQTYLSGNHMIT
HHHHHCCCCCCHHHHHHCCCCHHHEEEHHHHCCCHHHEEEEEEEEEECCCEEECCCEEEC
PRGYYGEIKQKKMDTGIGQDIMIRSFRTIEKELKNQEIPLDKKWALLHAIHTTADFDMEN
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCC
ILYADPDAVSTLYNKISGGEVPTIITDVTMAASGIRKGALQRLGVEVKCYLQDERVAEMA
CEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHH
SSKGITRTQAGIRRAVEEHPTALFVFGNAPTALMELCDLIRKGKATPAGIIAAPVGFVHV
HCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCEEECCCCEEEE
QESKHMVKPFIGIPKLIVEGRKGGSNLAATLVNAILCFNDAEQLKPGRDV
ECCCHHHHHHCCCCHHHEECCCCCCHHHHHHHHHHHHCCCHHHCCCCCCC
>Mature Secondary Structure
MNKGKIIVAGIGPGSEADITPAVLAAIQSSDVIIGYKYYFRFITHLLREGTECIDTGMKR
CCCCCEEEEECCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCHHHHHHCHHH
EQARAEQAFAYANEGKTVCVISSGDAGIYGMTPLIYEMKKESGSEIEIESYPGISAFQKA
HHHHHHHHHHEECCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCEEEEECCCCHHHHHHH
ASLLGAPIGHDFCVISLSDLMTPWELIEKRIHAAAMADFVTAIYNPKSEGRYWQLYRLKE
HHHHCCCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHH
LFLQERKPETPVGYVRQAGREEQEVFVTTLADLDPEQIDMFTVVLIGNSQTYLSGNHMIT
HHHHHCCCCCCHHHHHHCCCCHHHEEEHHHHCCCHHHEEEEEEEEEECCCEEECCCEEEC
PRGYYGEIKQKKMDTGIGQDIMIRSFRTIEKELKNQEIPLDKKWALLHAIHTTADFDMEN
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCC
ILYADPDAVSTLYNKISGGEVPTIITDVTMAASGIRKGALQRLGVEVKCYLQDERVAEMA
CEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHH
SSKGITRTQAGIRRAVEEHPTALFVFGNAPTALMELCDLIRKGKATPAGIIAAPVGFVHV
HCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCEEECCCCEEEE
QESKHMVKPFIGIPKLIVEGRKGGSNLAATLVNAILCFNDAEQLKPGRDV
ECCCHHHHHHCCCCHHHEECCCCCCHHHHHHHHHHHHCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]