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The map label for this gene is btuC [H]

Identifier: 150007663

GI number: 150007663

Start: 1177951

End: 1179015

Strand: Direct

Name: btuC [H]

Synonym: BDI_1018

Alternate gene names: 150007663

Gene position: 1177951-1179015 (Clockwise)

Preceding gene: 150007662

Following gene: 150007664

Centisome position: 24.48

GC content: 47.14

Gene sequence:

>1065_bases
ATGAGACATTCAAATACCCTATGGATGCTGGCGATTGTCACGGCTATTTTTGTTCTAATCTTTTTGAATTTGGTGTTGGG
GTCAGTCTCTATTCCTCTTCAATCGGTTTGGCATATTATCTGGAATTTAGGAAATGAGCCTATTACATGGCAGAATATTA
TCTGGAAATCCCGACTACCACAGGCATTGACAGCGTTGGTAGCGGGAGCTGGCTTATCCATCAGCGGCTTACAGATGCAA
ACCGTTTTCCGTAATCCATTGGCCGGACCTTCGGTCTTAGGTATCAGTTCGGGAGCGAGCATGGGTGTCGCTTTCGTGGT
GTTGTTAAGCGGTAGTTTAGGGGGCGTTGCCTTGAGTAAACTTGGTTTTATGGGGGAGATCGCCTTATCGATAGCGGCCG
TGATCGGTTCCTTATCCGTGATGGCGCTGATCGTGTATGTTTCCCAAAAGGTAAAAGGAAATGTCACGTTGTTGATTATC
GGTGTGATGATCGGTTACGTGGCAAACGCCGTGATCGGTGTACTTAAATTCTTTAGCGTCGAGGAGGATATCCGTGCATA
CGTGATTTGGGGATTGGGTAGTTTCGCCCGTGTTTCCGGTAATCAGATGACGTTGTTCGTGATTCTTATGACAATCTTGA
TCCCTCTCTCGTTCCTGCTTATCAAGACCATGAACTTGATGCTTCTTGGGGATAGCTACGCACGCAATTTGGGACTTAAT
ATCAAGCGGGCCCGTTTGTTGGTTATCACCTCGGCTGGGGTCCTTACGGCGATTGTCACTGCTTATTGCGGACCTATTAT
CTTCTTGGGGCTAGCCGTTCCGCATTTATGCCGGGCCATATTTCAAACTTCCGACCATCGGATTTTAATGCCTGCGGTCT
TATTCGCCGGTGCGGCGTTGGCGTTGATCTGTAATTTGATCGCCCGTATGCCGGGGTTCGAGGGAGCGTTACCTGTCAAC
TCGGTAACCGCTTTAGTAGGTGCTCCAGTAGTGGCCTCAGTATTATTTAGAAAACGTAAGAATGAATTGAACGAGCAAGA
TGAAACAAGATACGATTCATATTAA

Upstream 100 bases:

>100_bases
ACCGGAGATCGTCCTAGCGGATTTGCTTCATATCTTTCATCCGGATTTATTACCGGATCATGAGTCGGTCTATTATTCTC
GACTTAAATAAGGAACACTG

Downstream 100 bases:

>100_bases
CGGACTTTCGATCGGTTACCATTCTAAGAGTAGTACAAAGCTGGTAGCTAAAGGTATACACTCTACGATCTATAGTGGTG
AATTAACCTGTTTGCTGGGT

Product: iron(III) ABC transporter permease

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MRHSNTLWMLAIVTAIFVLIFLNLVLGSVSIPLQSVWHIIWNLGNEPITWQNIIWKSRLPQALTALVAGAGLSISGLQMQ
TVFRNPLAGPSVLGISSGASMGVAFVVLLSGSLGGVALSKLGFMGEIALSIAAVIGSLSVMALIVYVSQKVKGNVTLLII
GVMIGYVANAVIGVLKFFSVEEDIRAYVIWGLGSFARVSGNQMTLFVILMTILIPLSFLLIKTMNLMLLGDSYARNLGLN
IKRARLLVITSAGVLTAIVTAYCGPIIFLGLAVPHLCRAIFQTSDHRILMPAVLFAGAALALICNLIARMPGFEGALPVN
SVTALVGAPVVASVLFRKRKNELNEQDETRYDSY

Sequences:

>Translated_354_residues
MRHSNTLWMLAIVTAIFVLIFLNLVLGSVSIPLQSVWHIIWNLGNEPITWQNIIWKSRLPQALTALVAGAGLSISGLQMQ
TVFRNPLAGPSVLGISSGASMGVAFVVLLSGSLGGVALSKLGFMGEIALSIAAVIGSLSVMALIVYVSQKVKGNVTLLII
GVMIGYVANAVIGVLKFFSVEEDIRAYVIWGLGSFARVSGNQMTLFVILMTILIPLSFLLIKTMNLMLLGDSYARNLGLN
IKRARLLVITSAGVLTAIVTAYCGPIIFLGLAVPHLCRAIFQTSDHRILMPAVLFAGAALALICNLIARMPGFEGALPVN
SVTALVGAPVVASVLFRKRKNELNEQDETRYDSY
>Mature_354_residues
MRHSNTLWMLAIVTAIFVLIFLNLVLGSVSIPLQSVWHIIWNLGNEPITWQNIIWKSRLPQALTALVAGAGLSISGLQMQ
TVFRNPLAGPSVLGISSGASMGVAFVVLLSGSLGGVALSKLGFMGEIALSIAAVIGSLSVMALIVYVSQKVKGNVTLLII
GVMIGYVANAVIGVLKFFSVEEDIRAYVIWGLGSFARVSGNQMTLFVILMTILIPLSFLLIKTMNLMLLGDSYARNLGLN
IKRARLLVITSAGVLTAIVTAYCGPIIFLGLAVPHLCRAIFQTSDHRILMPAVLFAGAALALICNLIARMPGFEGALPVN
SVTALVGAPVVASVLFRKRKNELNEQDETRYDSY

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=287, Percent_Identity=32.7526132404181, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1790740, Length=321, Percent_Identity=31.1526479750779, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790741, Length=344, Percent_Identity=29.0697674418605, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786805, Length=297, Percent_Identity=31.986531986532, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786804, Length=278, Percent_Identity=30.5755395683453, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786347, Length=284, Percent_Identity=25.3521126760563, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37866; Mature: 37866

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS00659 GLYCOSYL_HYDROL_F5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHSNTLWMLAIVTAIFVLIFLNLVLGSVSIPLQSVWHIIWNLGNEPITWQNIIWKSRLP
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
QALTALVAGAGLSISGLQMQTVFRNPLAGPSVLGISSGASMGVAFVVLLSGSLGGVALSK
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHCCCCCHHHHHH
LGFMGEIALSIAAVIGSLSVMALIVYVSQKVKGNVTLLIIGVMIGYVANAVIGVLKFFSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EEDIRAYVIWGLGSFARVSGNQMTLFVILMTILIPLSFLLIKTMNLMLLGDSYARNLGLN
HHHHHEEEEECCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHCCCC
IKRARLLVITSAGVLTAIVTAYCGPIIFLGLAVPHLCRAIFQTSDHRILMPAVLFAGAAL
EEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHH
ALICNLIARMPGFEGALPVNSVTALVGAPVVASVLFRKRKNELNEQDETRYDSY
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCC
>Mature Secondary Structure
MRHSNTLWMLAIVTAIFVLIFLNLVLGSVSIPLQSVWHIIWNLGNEPITWQNIIWKSRLP
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
QALTALVAGAGLSISGLQMQTVFRNPLAGPSVLGISSGASMGVAFVVLLSGSLGGVALSK
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHCCCCCHHHHHH
LGFMGEIALSIAAVIGSLSVMALIVYVSQKVKGNVTLLIIGVMIGYVANAVIGVLKFFSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EEDIRAYVIWGLGSFARVSGNQMTLFVILMTILIPLSFLLIKTMNLMLLGDSYARNLGLN
HHHHHEEEEECCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHCCCC
IKRARLLVITSAGVLTAIVTAYCGPIIFLGLAVPHLCRAIFQTSDHRILMPAVLFAGAAL
EEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHH
ALICNLIARMPGFEGALPVNSVTALVGAPVVASVLFRKRKNELNEQDETRYDSY
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA