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The map label for this gene is pyrD [H]

Identifier: 150007198

GI number: 150007198

Start: 644757

End: 645734

Strand: Reverse

Name: pyrD [H]

Synonym: BDI_0543

Alternate gene names: 150007198

Gene position: 645734-644757 (Counterclockwise)

Preceding gene: 150007199

Following gene: 150007197

Centisome position: 13.42

GC content: 45.81

Gene sequence:

>978_bases
ATGATTGACATTAAAACCCAATACGCGGGGTTAACACTTCGCAATCCGATTATCGTCGGGAGCTCCGGACTCACCAATAA
GGCGGAACGTAACAGGGATTTTGAGAAAGCAGGCGCTGGAGCTATCGTATTGAAATCTCTTTTCGAAGAGCAGATCGAGA
TGCAGAGCGAGGCTTTGATGCAAGACTCCGATTACCCCGAAGCGGCGGATTATATCCGTGGTTATGTAAAAGCGAATCAA
GTAAATGATTATCTGGAACTGATCAAGAAGAGCAAGGAATTATGTACGATCCCCATTATCGCCAGCATCAATTGCTATAA
GGCGGACGCTTGGATCGACTTTGCCCGCCAAATTGAGTTAGCGGGAGCGGACGCTTTGGAATTGAACGTGTTCTTCATGG
AAACCGAGCTGACCGAAGATTTCGAGAGTATCCGGGATACGTATGTCAGTATCATCCGCAAGGTAAAAGAGACCGTATCG
ATTCCGGTTATCATGAAGATCGGAAAGAATTACAGCAATATTCCTTCACTGGTTAATTTGTTGAAAGTAAACGGTGCTGA
TGGTGTCGTGCTATTCAACCGTTTCTACCAGCCGGATATCGACATCAATAATATGCAGATCGTTTCGGGTAATGTATTTA
GCAATCATTCCGATTTGAGTGACACGATTCGCTGGACGGCTATCGTATCCGGAAAGATCCCGGGAATCAGTATCGCTTCC
TCTACCGGTGTGCATGATTGGGAAGATGTCGTTAAATGTCTATTGGCCGGCGCTTCCGCCGTACAGATGTGTAGCGCTGT
CTATACACATGGAGCGGAAATCATCTCCCAAGTATTGACTTGCGTGGAAGAGTGGATGCATCAGGCACATTACCAATCCC
TTTCCCAATTCCAAGGCAAATTGAATTACGCCAATATCCCGAACCCGGCGATGTATGAGCGTTCACAATTCATGAAATAT
TTCTCCAACAGAGATTAA

Upstream 100 bases:

>100_bases
CGATCGCTATCCAAGAAGGAAGCACCTTGATACGGGTGGGTACCAGTATCTTTGGCGAACGGGAATATTAAAGTAATTAT
TAAATCTAAATATAGGCAAC

Downstream 100 bases:

>100_bases
AAGAAATACCTAGTAGTAGAGACGGGGCGTGCCCCGTCTCTACTATAGGATAATATACAATAGTCTTAATTATTTTCTAC
TAGAAAGTATTTTTATTAGA

Product: dihydroorotate dehydrogenase 2

Products: NA

Alternate protein names: DHOdehase; DHOD; DHODase; Dihydroorotate oxidase [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MIDIKTQYAGLTLRNPIIVGSSGLTNKAERNRDFEKAGAGAIVLKSLFEEQIEMQSEALMQDSDYPEAADYIRGYVKANQ
VNDYLELIKKSKELCTIPIIASINCYKADAWIDFARQIELAGADALELNVFFMETELTEDFESIRDTYVSIIRKVKETVS
IPVIMKIGKNYSNIPSLVNLLKVNGADGVVLFNRFYQPDIDINNMQIVSGNVFSNHSDLSDTIRWTAIVSGKIPGISIAS
STGVHDWEDVVKCLLAGASAVQMCSAVYTHGAEIISQVLTCVEEWMHQAHYQSLSQFQGKLNYANIPNPAMYERSQFMKY
FSNRD

Sequences:

>Translated_325_residues
MIDIKTQYAGLTLRNPIIVGSSGLTNKAERNRDFEKAGAGAIVLKSLFEEQIEMQSEALMQDSDYPEAADYIRGYVKANQ
VNDYLELIKKSKELCTIPIIASINCYKADAWIDFARQIELAGADALELNVFFMETELTEDFESIRDTYVSIIRKVKETVS
IPVIMKIGKNYSNIPSLVNLLKVNGADGVVLFNRFYQPDIDINNMQIVSGNVFSNHSDLSDTIRWTAIVSGKIPGISIAS
STGVHDWEDVVKCLLAGASAVQMCSAVYTHGAEIISQVLTCVEEWMHQAHYQSLSQFQGKLNYANIPNPAMYERSQFMKY
FSNRD
>Mature_325_residues
MIDIKTQYAGLTLRNPIIVGSSGLTNKAERNRDFEKAGAGAIVLKSLFEEQIEMQSEALMQDSDYPEAADYIRGYVKANQ
VNDYLELIKKSKELCTIPIIASINCYKADAWIDFARQIELAGADALELNVFFMETELTEDFESIRDTYVSIIRKVKETVS
IPVIMKIGKNYSNIPSLVNLLKVNGADGVVLFNRFYQPDIDINNMQIVSGNVFSNHSDLSDTIRWTAIVSGKIPGISIAS
STGVHDWEDVVKCLLAGASAVQMCSAVYTHGAEIISQVLTCVEEWMHQAHYQSLSQFQGKLNYANIPNPAMYERSQFMKY
FSNRD

Specific function: Unknown

COG id: COG0167

COG function: function code F; Dihydroorotate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=336, Percent_Identity=25.297619047619, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71984108, Length=355, Percent_Identity=23.0985915492958, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005720
- InterPro:   IPR012135
- InterPro:   IPR001295 [H]

Pfam domain/function: PF01180 DHO_dh [H]

EC number: =1.3.3.1 [H]

Molecular weight: Translated: 36387; Mature: 36387

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDIKTQYAGLTLRNPIIVGSSGLTNKAERNRDFEKAGAGAIVLKSLFEEQIEMQSEALM
CCEECCCCCCEEECCCEEECCCCCCCHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
QDSDYPEAADYIRGYVKANQVNDYLELIKKSKELCTIPIIASINCYKADAWIDFARQIEL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEHHHHHHHHHHHHH
AGADALELNVFFMETELTEDFESIRDTYVSIIRKVKETVSIPVIMKIGKNYSNIPSLVNL
CCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCHHHHHHHH
LKVNGADGVVLFNRFYQPDIDINNMQIVSGNVFSNHSDLSDTIRWTAIVSGKIPGISIAS
HHCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHEEEEEEEECCCCCEEEEC
STGVHDWEDVVKCLLAGASAVQMCSAVYTHGAEIISQVLTCVEEWMHQAHYQSLSQFQGK
CCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LNYANIPNPAMYERSQFMKYFSNRD
CCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIDIKTQYAGLTLRNPIIVGSSGLTNKAERNRDFEKAGAGAIVLKSLFEEQIEMQSEALM
CCEECCCCCCEEECCCEEECCCCCCCHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
QDSDYPEAADYIRGYVKANQVNDYLELIKKSKELCTIPIIASINCYKADAWIDFARQIEL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEHHHHHHHHHHHHH
AGADALELNVFFMETELTEDFESIRDTYVSIIRKVKETVSIPVIMKIGKNYSNIPSLVNL
CCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCHHHHHHHH
LKVNGADGVVLFNRFYQPDIDINNMQIVSGNVFSNHSDLSDTIRWTAIVSGKIPGISIAS
HHCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHEEEEEEEECCCCCEEEEC
STGVHDWEDVVKCLLAGASAVQMCSAVYTHGAEIISQVLTCVEEWMHQAHYQSLSQFQGK
CCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LNYANIPNPAMYERSQFMKYFSNRD
CCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11029001 [H]