Click here to switch to the map view.

The map label for this gene is gap [H]

Identifier: 150006951

GI number: 150006951

Start: 323100

End: 324101

Strand: Reverse

Name: gap [H]

Synonym: BDI_0287

Alternate gene names: 150006951

Gene position: 324101-323100 (Counterclockwise)

Preceding gene: 150006953

Following gene: 150006950

Centisome position: 6.74

GC content: 44.81

Gene sequence:

>1002_bases
ATGATCAAACTAGGTATTAACGGTTTTGGCCGTATCGGACGTATGGTGTTCCGTGCTGCAGTTGCTAACTTTGGCAACGA
CATTCAAGTTGTAGGTATCAACGACCTTTTGGATGCTGATTACTTGGCATACATGTTGAAATATGACTCAGTACACGGTC
GTTTCGACGGCGAAGTAGCTGTAGAAGACGGCGCTTTGGTTGTAAACGGTAACAAGATCCGTTTAACTGCTGAGATGGAT
CCTGCTAACTTGAAATGGAACGAGGTTGACGCTGACGTTGTTGTTGAGTCTACTGGTTTCTTCTTGACAGACGAGACAGC
TCGCAAACACATCCAAGCTGGCGCTAAGAAAGTTATCATGTCTGCTCCTTCTAAGGATGCTACTCCTATGTTCGTTTACG
GTGTTAACCATACAACTTACGCAGGTCAAGACATTATCTCTAACGCTTCTTGTACTACAAACTGCTTGGCTCCTATCGCT
AAGGTTTTGAACGACAAGTTCGGTATCGTTAAAGGTTTGATGACAACAGTTCACGCTGCTACAGCTACTCAGAAGACTGT
AGACGGTCCTTCTAAGAAAGACTGGAGAGGTGGTCGTGGTATCCTTGAGAACATCATCCCTTCTTCAACGGGTGCCGCTA
AGGCTGTAGGTAAAGTATTACCTGTATTGAACGGCAAATTGACAGGTATGGCTTTCCGTGTACCGACTTCTGATGTTTCT
GTTGTTGACTTGACAGTAGTTCTTGAGAAAGAGGCTTCTATGGCTGACATCTGCGCTGCAATGAAGGAGGCTTCTGAAGG
CGAATTGAAAGGTGTTCTTGGTTATACTGAAGACGCAGTTGTTTCAACTGACTTCCGTGGCTGTGCTAACACTTCTATCT
TCGACGCTAAAGCTGGTATCTCTTTGGATTCTAACTTCGCTAAGATCGTATCTTGGTACGACAACGAGTGGGGTTATTCA
AACAAAGTTTGTGAGATGGCTCGCGTTATCGCTGGTAAGTAA

Upstream 100 bases:

>100_bases
TCGTTAAAGCAAGGGATAAAATGAATATCTACTCCTTGCGATGAATAAGAGATAAAAATAAAGACTTATTATTAATAAAC
CCATAAAAAGTTTTATTACA

Downstream 100 bases:

>100_bases
TTTATTACCACTCTACATAGAAAAGGCTATCCTCTTTGAGGATGGCCTTTTTTTTCGTACGTTTGTATCATGAAATCATA
TGAACTTATCACGATTCTAG

Product: glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MIKLGINGFGRIGRMVFRAAVANFGNDIQVVGINDLLDADYLAYMLKYDSVHGRFDGEVAVEDGALVVNGNKIRLTAEMD
PANLKWNEVDADVVVESTGFFLTDETARKHIQAGAKKVIMSAPSKDATPMFVYGVNHTTYAGQDIISNASCTTNCLAPIA
KVLNDKFGIVKGLMTTVHAATATQKTVDGPSKKDWRGGRGILENIIPSSTGAAKAVGKVLPVLNGKLTGMAFRVPTSDVS
VVDLTVVLEKEASMADICAAMKEASEGELKGVLGYTEDAVVSTDFRGCANTSIFDAKAGISLDSNFAKIVSWYDNEWGYS
NKVCEMARVIAGK

Sequences:

>Translated_333_residues
MIKLGINGFGRIGRMVFRAAVANFGNDIQVVGINDLLDADYLAYMLKYDSVHGRFDGEVAVEDGALVVNGNKIRLTAEMD
PANLKWNEVDADVVVESTGFFLTDETARKHIQAGAKKVIMSAPSKDATPMFVYGVNHTTYAGQDIISNASCTTNCLAPIA
KVLNDKFGIVKGLMTTVHAATATQKTVDGPSKKDWRGGRGILENIIPSSTGAAKAVGKVLPVLNGKLTGMAFRVPTSDVS
VVDLTVVLEKEASMADICAAMKEASEGELKGVLGYTEDAVVSTDFRGCANTSIFDAKAGISLDSNFAKIVSWYDNEWGYS
NKVCEMARVIAGK
>Mature_333_residues
MIKLGINGFGRIGRMVFRAAVANFGNDIQVVGINDLLDADYLAYMLKYDSVHGRFDGEVAVEDGALVVNGNKIRLTAEMD
PANLKWNEVDADVVVESTGFFLTDETARKHIQAGAKKVIMSAPSKDATPMFVYGVNHTTYAGQDIISNASCTTNCLAPIA
KVLNDKFGIVKGLMTTVHAATATQKTVDGPSKKDWRGGRGILENIIPSSTGAAKAVGKVLPVLNGKLTGMAFRVPTSDVS
VVDLTVVLEKEASMADICAAMKEASEGELKGVLGYTEDAVVSTDFRGCANTSIFDAKAGISLDSNFAKIVSWYDNEWGYS
NKVCEMARVIAGK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=62.874251497006, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI7657116, Length=335, Percent_Identity=56.7164179104478, Blast_Score=389, Evalue=1e-108,
Organism=Escherichia coli, GI1788079, Length=325, Percent_Identity=76.3076923076923, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI1789295, Length=333, Percent_Identity=38.4384384384384, Blast_Score=237, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI32566163, Length=338, Percent_Identity=62.4260355029586, Blast_Score=407, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=61.8343195266272, Blast_Score=406, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17568413, Length=338, Percent_Identity=62.4260355029586, Blast_Score=406, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=61.8343195266272, Blast_Score=405, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6322409, Length=333, Percent_Identity=63.6636636636637, Blast_Score=421, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6322468, Length=333, Percent_Identity=62.1621621621622, Blast_Score=414, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6321631, Length=333, Percent_Identity=61.8618618618619, Blast_Score=411, Evalue=1e-116,
Organism=Drosophila melanogaster, GI17933600, Length=335, Percent_Identity=62.089552238806, Blast_Score=409, Evalue=1e-114,
Organism=Drosophila melanogaster, GI18110149, Length=335, Percent_Identity=62.089552238806, Blast_Score=409, Evalue=1e-114,
Organism=Drosophila melanogaster, GI85725000, Length=335, Percent_Identity=61.7910447761194, Blast_Score=408, Evalue=1e-114,
Organism=Drosophila melanogaster, GI22023983, Length=335, Percent_Identity=61.7910447761194, Blast_Score=408, Evalue=1e-114,
Organism=Drosophila melanogaster, GI19922412, Length=328, Percent_Identity=59.4512195121951, Blast_Score=379, Evalue=1e-105,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35535; Mature: 35535

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLGINGFGRIGRMVFRAAVANFGNDIQVVGINDLLDADYLAYMLKYDSVHGRFDGEVA
CEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCEEE
VEDGALVVNGNKIRLTAEMDPANLKWNEVDADVVVESTGFFLTDETARKHIQAGAKKVIM
EECCEEEEECCEEEEEEECCCCCCEECCCCCEEEEECCCCEEECHHHHHHHHHHHHHEEE
SAPSKDATPMFVYGVNHTTYAGQDIISNASCTTNCLAPIAKVLNDKFGIVKGLMTTVHAA
ECCCCCCCEEEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TATQKTVDGPSKKDWRGGRGILENIIPSSTGAAKAVGKVLPVLNGKLTGMAFRVPTSDVS
HHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCE
VVDLTVVLEKEASMADICAAMKEASEGELKGVLGYTEDAVVSTDFRGCANTSIFDAKAGI
EEEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEECCCCCCCCCCEEECCCCC
SLDSNFAKIVSWYDNEWGYSNKVCEMARVIAGK
CCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MIKLGINGFGRIGRMVFRAAVANFGNDIQVVGINDLLDADYLAYMLKYDSVHGRFDGEVA
CEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCEEE
VEDGALVVNGNKIRLTAEMDPANLKWNEVDADVVVESTGFFLTDETARKHIQAGAKKVIM
EECCEEEEECCEEEEEEECCCCCCEECCCCCEEEEECCCCEEECHHHHHHHHHHHHHEEE
SAPSKDATPMFVYGVNHTTYAGQDIISNASCTTNCLAPIAKVLNDKFGIVKGLMTTVHAA
ECCCCCCCEEEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TATQKTVDGPSKKDWRGGRGILENIIPSSTGAAKAVGKVLPVLNGKLTGMAFRVPTSDVS
HHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCE
VVDLTVVLEKEASMADICAAMKEASEGELKGVLGYTEDAVVSTDFRGCANTSIFDAKAGI
EEEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEECCCCCCCCCCEEECCCCC
SLDSNFAKIVSWYDNEWGYSNKVCEMARVIAGK
CCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA