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The map label for this gene is lacZ [H]

Identifier: 150006894

GI number: 150006894

Start: 240227

End: 243565

Strand: Reverse

Name: lacZ [H]

Synonym: BDI_0230

Alternate gene names: 150006894

Gene position: 243565-240227 (Counterclockwise)

Preceding gene: 150006895

Following gene: 150006891

Centisome position: 5.06

GC content: 45.4

Gene sequence:

>3339_bases
ATGAACTCTATCAAAAAAATGATGCTTTCCGGAGCATTAGGTTGCCTTATTTCCGGAATGGCTTATGCGGACGGTTCTTC
ACCCCAACCCGTAAAACCTTATTGGCAAGACATTCAAGTCGTAGCCGTAAACAAGGAAAAACCCAGAAGCTCCTTCATGA
GTTATGCGGACCGAGAAACCGCCCTCACCTCTCGATTTGAGAAAAGCCCGTACTATTTCCTATTAAACGGTACTTGGAAA
TTTTTCTTTGTCGACTCTTACAAAGATCTTCCTCAAAATATCACAGATCCTTCCGTTAATACCTCTTCATGGGATGATAT
AACCGTTCCCGGAAACTGGGAAGTACAAGGACATGGCGTAGCCATTTATACGAATCATGGTTACGAGTTTAAACCAAGAA
ATCCCCAACCTCCGTTATTGCCGGAAGCGAATCCGGTTGGCGTATACCGCAGAGACATCGAGATACCCGCAAGTTGGGAT
AACCGGGATATTTATTTACACATCGGCGGAGCTAAATCCGGCCTTTACGTATATTTAAACGGGAAAGAAGTGGGTTATAG
CGAGGATTCCAAAAATCCCGCCGAGTTCCTGATCAATAAATACCTGCAACCCGGAAAGAATGTGCTTACATTAAAGATAT
TCCGTTGGAGCACCGGTTCTTATTTGGAATGTCAGGATTTCTGGAGAATGAGCGGTATCGAACGTGACGTATTCCTTTGG
TCTCAACCCAAGGCCAGTATTCAAGATTTCCGTGTCGTCTCAACCTTGGACGATACGTATACGAATGGAATCTTCAAACT
GGCGGTAGACTTAAAGAATCATACCCAAGAAACGAAAAATTTAAATGTCGGATATGAGCTTTTGGACGCAAAAGGTAATC
TTGTGACCTCCGAGGCTAATGATATATGGGTAAGTCCTGCAAGTCCTCAAACAGTATCTTTCGAGTATGATTTAAAGAAC
GTAGCCCCTTGGAGTGCCGAGCATCCGAATCTATACAAATTATTGATGACGATAAAAGAAGAGGGTAAGGTAATCGAGGT
AGTTCCATTCAACGTTGGTTTCCGCCGGTTCGAGATGAAGCAAATTGACCAAGTAGCGGAAGACGGAAAACCTTATACGG
TCTTATTGTTCAATGGGCAACCGGTTAAGTTCAAGGGTGTCAATATTCATGAGCATAACCCGGAAACCGGACATTACGTA
ACCGAGGAACTCATGCGTAAGGATTTCGAGCTGATGAAGCAAAACAATATCAACGCTGTCCGCCTATGCCACTATCCGCA
AGACCGTAAATTCTATGAACTCTGCGACGAATACGGATTGTATGTTTACGATGAAGCGAATATCGAGTCTCACGGTATGT
ATTACAGCCTGAAAAAAGGCGGCACTTTGGGTAATAATCCGGAATGGCTGATCCCGCATATGGACCGTACGATGAATATG
TACGAACGAAACAAGAATTATCCGAGCGTTACTTTCTGGTCACTCGGAAACGAGGCTGGAAACGGATACAACTTCTATCA
AACTTATTTATATCTGAAAGACAAGGAAATAAATAGCATGAATCGTCCGGTGAACTATGAACGTGCCCTTTGGGAATGGA
ATACGGATATGTACGTACCTCAATACCCGAGCGCTGAATGGCTAGAGGAAATCGGGCGTAAGGGTAGTGATCGTCCGGTA
GCTCCTTCGGAGTATTCACATGCGATGGGAAACTCTTCCGGCAACTTATGGGATCAATGGAAAGCTATCTATAAATACCC
GAACCTGCAAGGCGGATTCATCTGGGACTGGGTGGACCAAGGTATCTTGGAAAAAGATAAGAATGGACGTGAATATTATA
CCTATGGTGGTGACTATGGAGTAAACGCCCCTAGTGACGGAAACTTCCTTTGCAACGGTATAGTAAACCCGGATCGTACC
CCGCATCCCGCTATGGCAGAGGTTAAATACGCCCATCAAAATATCGGGTTTGAGGCGATCGATTTAGCGAACGGTTTATT
CCGCGTCACGAACCGTTTTTATTTCACGAACCTAAAGAAATATATGGTCCACTATAGCGTAACAGCCAATAATAAAGTTG
TACGCTCCGGTAAAGTCTCTTTGGACATAGAACCCCAAGCTTCTAAGGAATTTACGGTTCCCGTAGGCAACTTAAAGCCA
CAAGCCGGTACGGAATATTTCGTAAACTTCAACGTAACGACCGTAGAAAAAGAGCCGTTAATCCCTATCGGACACGAAAT
CGCTTGCGATCAATTCCGCTTACCGATCGAAAGCCCCAAGAAGGCGTTTAAGACCAGCGGCCCTAAATTAACGGTTTCGA
CAAATGGAGATAACTTATCGGCATCCTCCTCAAAGGTAAACTTCGTGTTTAACAGGAAGACAGGAATCGTTACTTCTTAT
AAAGTGGATGGTACGGAATATTTCAGCGAGGGTTTCGGTATCCAACCGAACTTCTGGCGTGCGCCGACCGATAACGATTA
CGGAAACGGTATGCCAAAACGCTTGCAAGTCTGGAAGGAAAGCAGCAAGAACTTCAACGTGACAGACGCTACCGTCACTA
TGGATGGCAATAACGCCGTGGTTAGCGTGAACTATTTATTGCCGGCAGGAAATCTATACATTGTTAATTATACGATCTAT
CCAAGCGGAGCCGTAAATGTGGCCGCCCGTTTCACATCCACGGATATGGATGCCGCCCAAACCGAGGTATCGGAAGCTAC
TCGCACGGCAACTTTCACTCCGGGACGTGACGCCGCCCGTAAAGAGGCTTCCAAATTGAATGTTCCCCGTATCGGTGTTC
GCTTCCGCTTACCGGCAAGCATGAATCAAGTGGAATATTTCGGACGAGGACCTGCTGAGAACTACTTGGATAGAAACGCC
GGTAGTATGGTCGGCTTATATAAATCTACAGCCGAGGAATTATATTTCCCATATGTACGCCCGCAGGAAAACGGTCATCA
TACCGACACTCGTTGGGTATCACTTAGTACCGGCAAGAAAGGCTTGTTGATCCAAGCGGATAATACGATTGGATTTAACG
CTTTGCGTAATTCCATAGAGGATTTCGATGACGAGGAAGCAACTGGGCTACCCCGTCAATGGAGTAATTTCACACCAGAG
CAAGTAGCGAACCATGATGAAGCCGCAGCAAAGAACGTATTACGTCGCCAGCATCATATCAACAATATCACGCCTCGCGA
CTTCGTTGAAGTTTGCGTCGACTTGAAACAACAAGGTGTAGCAGGTTATGATAGCTGGGGTTCACGTCCGGAACCAGCTT
ATACATTACCCGCAAACCGGGAATACAACTGGGGCTTTACCCTTATTCCGCTTAAATAA

Upstream 100 bases:

>100_bases
AAATTGAGAATTGAGAATTGAAAATTACGTAGAGTCACTTCTAATTCTCAATTCTCAATTTTCAATTCCCCAGTGCTAAT
CTAAATAAAATACGATGAAT

Downstream 100 bases:

>100_bases
AGAAAAGCCATAACTTATCCATAACAAAGGGAGTGTATTAGGCTTAATCCAATACACTCCCTTTGTTTATACTACTGCAA
CGGCTTTGCAGCACTACTGC

Product: beta-galactosidase

Products: NA

Alternate protein names: Beta-gal; Lactase [H]

Number of amino acids: Translated: 1112; Mature: 1112

Protein sequence:

>1112_residues
MNSIKKMMLSGALGCLISGMAYADGSSPQPVKPYWQDIQVVAVNKEKPRSSFMSYADRETALTSRFEKSPYYFLLNGTWK
FFFVDSYKDLPQNITDPSVNTSSWDDITVPGNWEVQGHGVAIYTNHGYEFKPRNPQPPLLPEANPVGVYRRDIEIPASWD
NRDIYLHIGGAKSGLYVYLNGKEVGYSEDSKNPAEFLINKYLQPGKNVLTLKIFRWSTGSYLECQDFWRMSGIERDVFLW
SQPKASIQDFRVVSTLDDTYTNGIFKLAVDLKNHTQETKNLNVGYELLDAKGNLVTSEANDIWVSPASPQTVSFEYDLKN
VAPWSAEHPNLYKLLMTIKEEGKVIEVVPFNVGFRRFEMKQIDQVAEDGKPYTVLLFNGQPVKFKGVNIHEHNPETGHYV
TEELMRKDFELMKQNNINAVRLCHYPQDRKFYELCDEYGLYVYDEANIESHGMYYSLKKGGTLGNNPEWLIPHMDRTMNM
YERNKNYPSVTFWSLGNEAGNGYNFYQTYLYLKDKEINSMNRPVNYERALWEWNTDMYVPQYPSAEWLEEIGRKGSDRPV
APSEYSHAMGNSSGNLWDQWKAIYKYPNLQGGFIWDWVDQGILEKDKNGREYYTYGGDYGVNAPSDGNFLCNGIVNPDRT
PHPAMAEVKYAHQNIGFEAIDLANGLFRVTNRFYFTNLKKYMVHYSVTANNKVVRSGKVSLDIEPQASKEFTVPVGNLKP
QAGTEYFVNFNVTTVEKEPLIPIGHEIACDQFRLPIESPKKAFKTSGPKLTVSTNGDNLSASSSKVNFVFNRKTGIVTSY
KVDGTEYFSEGFGIQPNFWRAPTDNDYGNGMPKRLQVWKESSKNFNVTDATVTMDGNNAVVSVNYLLPAGNLYIVNYTIY
PSGAVNVAARFTSTDMDAAQTEVSEATRTATFTPGRDAARKEASKLNVPRIGVRFRLPASMNQVEYFGRGPAENYLDRNA
GSMVGLYKSTAEELYFPYVRPQENGHHTDTRWVSLSTGKKGLLIQADNTIGFNALRNSIEDFDDEEATGLPRQWSNFTPE
QVANHDEAAAKNVLRRQHHINNITPRDFVEVCVDLKQQGVAGYDSWGSRPEPAYTLPANREYNWGFTLIPLK

Sequences:

>Translated_1112_residues
MNSIKKMMLSGALGCLISGMAYADGSSPQPVKPYWQDIQVVAVNKEKPRSSFMSYADRETALTSRFEKSPYYFLLNGTWK
FFFVDSYKDLPQNITDPSVNTSSWDDITVPGNWEVQGHGVAIYTNHGYEFKPRNPQPPLLPEANPVGVYRRDIEIPASWD
NRDIYLHIGGAKSGLYVYLNGKEVGYSEDSKNPAEFLINKYLQPGKNVLTLKIFRWSTGSYLECQDFWRMSGIERDVFLW
SQPKASIQDFRVVSTLDDTYTNGIFKLAVDLKNHTQETKNLNVGYELLDAKGNLVTSEANDIWVSPASPQTVSFEYDLKN
VAPWSAEHPNLYKLLMTIKEEGKVIEVVPFNVGFRRFEMKQIDQVAEDGKPYTVLLFNGQPVKFKGVNIHEHNPETGHYV
TEELMRKDFELMKQNNINAVRLCHYPQDRKFYELCDEYGLYVYDEANIESHGMYYSLKKGGTLGNNPEWLIPHMDRTMNM
YERNKNYPSVTFWSLGNEAGNGYNFYQTYLYLKDKEINSMNRPVNYERALWEWNTDMYVPQYPSAEWLEEIGRKGSDRPV
APSEYSHAMGNSSGNLWDQWKAIYKYPNLQGGFIWDWVDQGILEKDKNGREYYTYGGDYGVNAPSDGNFLCNGIVNPDRT
PHPAMAEVKYAHQNIGFEAIDLANGLFRVTNRFYFTNLKKYMVHYSVTANNKVVRSGKVSLDIEPQASKEFTVPVGNLKP
QAGTEYFVNFNVTTVEKEPLIPIGHEIACDQFRLPIESPKKAFKTSGPKLTVSTNGDNLSASSSKVNFVFNRKTGIVTSY
KVDGTEYFSEGFGIQPNFWRAPTDNDYGNGMPKRLQVWKESSKNFNVTDATVTMDGNNAVVSVNYLLPAGNLYIVNYTIY
PSGAVNVAARFTSTDMDAAQTEVSEATRTATFTPGRDAARKEASKLNVPRIGVRFRLPASMNQVEYFGRGPAENYLDRNA
GSMVGLYKSTAEELYFPYVRPQENGHHTDTRWVSLSTGKKGLLIQADNTIGFNALRNSIEDFDDEEATGLPRQWSNFTPE
QVANHDEAAAKNVLRRQHHINNITPRDFVEVCVDLKQQGVAGYDSWGSRPEPAYTLPANREYNWGFTLIPLK
>Mature_1112_residues
MNSIKKMMLSGALGCLISGMAYADGSSPQPVKPYWQDIQVVAVNKEKPRSSFMSYADRETALTSRFEKSPYYFLLNGTWK
FFFVDSYKDLPQNITDPSVNTSSWDDITVPGNWEVQGHGVAIYTNHGYEFKPRNPQPPLLPEANPVGVYRRDIEIPASWD
NRDIYLHIGGAKSGLYVYLNGKEVGYSEDSKNPAEFLINKYLQPGKNVLTLKIFRWSTGSYLECQDFWRMSGIERDVFLW
SQPKASIQDFRVVSTLDDTYTNGIFKLAVDLKNHTQETKNLNVGYELLDAKGNLVTSEANDIWVSPASPQTVSFEYDLKN
VAPWSAEHPNLYKLLMTIKEEGKVIEVVPFNVGFRRFEMKQIDQVAEDGKPYTVLLFNGQPVKFKGVNIHEHNPETGHYV
TEELMRKDFELMKQNNINAVRLCHYPQDRKFYELCDEYGLYVYDEANIESHGMYYSLKKGGTLGNNPEWLIPHMDRTMNM
YERNKNYPSVTFWSLGNEAGNGYNFYQTYLYLKDKEINSMNRPVNYERALWEWNTDMYVPQYPSAEWLEEIGRKGSDRPV
APSEYSHAMGNSSGNLWDQWKAIYKYPNLQGGFIWDWVDQGILEKDKNGREYYTYGGDYGVNAPSDGNFLCNGIVNPDRT
PHPAMAEVKYAHQNIGFEAIDLANGLFRVTNRFYFTNLKKYMVHYSVTANNKVVRSGKVSLDIEPQASKEFTVPVGNLKP
QAGTEYFVNFNVTTVEKEPLIPIGHEIACDQFRLPIESPKKAFKTSGPKLTVSTNGDNLSASSSKVNFVFNRKTGIVTSY
KVDGTEYFSEGFGIQPNFWRAPTDNDYGNGMPKRLQVWKESSKNFNVTDATVTMDGNNAVVSVNYLLPAGNLYIVNYTIY
PSGAVNVAARFTSTDMDAAQTEVSEATRTATFTPGRDAARKEASKLNVPRIGVRFRLPASMNQVEYFGRGPAENYLDRNA
GSMVGLYKSTAEELYFPYVRPQENGHHTDTRWVSLSTGKKGLLIQADNTIGFNALRNSIEDFDDEEATGLPRQWSNFTPE
QVANHDEAAAKNVLRRQHHINNITPRDFVEVCVDLKQQGVAGYDSWGSRPEPAYTLPANREYNWGFTLIPLK

Specific function: The Wild-Type Enzyme Is An Ineffective Lactase. Two Classes Of Point Mutations Dramatically Improve Activity Of The Enzyme. [C]

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI268834192, Length=417, Percent_Identity=25.6594724220624, Blast_Score=96, Evalue=3e-19,
Organism=Escherichia coli, GI48994920, Length=1086, Percent_Identity=29.3738489871087, Blast_Score=481, Evalue=1e-136,
Organism=Escherichia coli, GI1786539, Length=993, Percent_Identity=31.1178247734139, Blast_Score=460, Evalue=1e-130,
Organism=Escherichia coli, GI1787903, Length=380, Percent_Identity=27.1052631578947, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17510825, Length=367, Percent_Identity=23.9782016348774, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI62471735, Length=408, Percent_Identity=24.5098039215686, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19922582, Length=408, Percent_Identity=24.5098039215686, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24655438, Length=408, Percent_Identity=24.5098039215686, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24651745, Length=285, Percent_Identity=23.1578947368421, Blast_Score=80, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR011013
- InterPro:   IPR014718
- InterPro:   IPR006101
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR004199
- InterPro:   IPR006102
- InterPro:   IPR006103
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF02929 Bgal_small_N; PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 126386; Mature: 126386

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSIKKMMLSGALGCLISGMAYADGSSPQPVKPYWQDIQVVAVNKEKPRSSFMSYADRET
CCHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHH
ALTSRFEKSPYYFLLNGTWKFFFVDSYKDLPQNITDPSVNTSSWDDITVPGNWEVQGHGV
HHHHHHCCCCEEEEEECEEEEEEEECHHHCCCCCCCCCCCCCCCCCEECCCCEEEEECCE
AIYTNHGYEFKPRNPQPPLLPEANPVGVYRRDIEIPASWDNRDIYLHIGGAKSGLYVYLN
EEEECCCEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCEEEEEC
GKEVGYSEDSKNPAEFLINKYLQPGKNVLTLKIFRWSTGSYLECQDFWRMSGIERDVFLW
CCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEHHHHHHHCCCCCEEEEE
SQPKASIQDFRVVSTLDDTYTNGIFKLAVDLKNHTQETKNLNVGYELLDAKGNLVTSEAN
CCCCCCHHHEEEEEHHHHHHCCCEEEEEEEHHHCCHHHCCCCCCEEEEECCCCEEEECCC
DIWVSPASPQTVSFEYDLKNVAPWSAEHPNLYKLLMTIKEEGKVIEVVPFNVGFRRFEMK
EEEECCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHH
QIDQVAEDGKPYTVLLFNGQPVKFKGVNIHEHNPETGHYVTEELMRKDFELMKQNNINAV
HHHHHHHCCCCEEEEEECCCCEEEECCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEE
RLCHYPQDRKFYELCDEYGLYVYDEANIESHGMYYSLKKGGTLGNNPEWLIPHMDRTMNM
EEECCCCCCHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCCCCCCCEEECCCHHHHHH
YERNKNYPSVTFWSLGNEAGNGYNFYQTYLYLKDKEINSMNRPVNYERALWEWNTDMYVP
HHHCCCCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCEECC
QYPSAEWLEEIGRKGSDRPVAPSEYSHAMGNSSGNLWDQWKAIYKYPNLQGGFIWDWVDQ
CCCCHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEHHHHC
GILEKDKNGREYYTYGGDYGVNAPSDGNFLCNGIVNPDRTPHPAMAEVKYAHQNIGFEAI
CHHHCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHCCCEEEE
DLANGLFRVTNRFYFTNLKKYMVHYSVTANNKVVRSGKVSLDIEPQASKEFTVPVGNLKP
HHHHHHHHHHHHHHHHCCEEEEEEEEEECCCEEEECCEEEEEECCCCCCEEEEECCCCCC
QAGTEYFVNFNVTTVEKEPLIPIGHEIACDQFRLPIESPKKAFKTSGPKLTVSTNGDNLS
CCCCEEEEEEEEEEECCCCCCCCCCEECCCCEECCCCCCHHHHHCCCCEEEEEECCCCCC
ASSSKVNFVFNRKTGIVTSYKVDGTEYFSEGFGIQPNFWRAPTDNDYGNGMPKRLQVWKE
CCCCEEEEEEECCCCEEEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
SSKNFNVTDATVTMDGNNAVVSVNYLLPAGNLYIVNYTIYPSGAVNVAARFTSTDMDAAQ
CCCCCEEEEEEEEECCCCEEEEEEEEECCCCEEEEEEEECCCCCEEEEEEEECCCCHHHH
TEVSEATRTATFTPGRDAARKEASKLNVPRIGVRFRLPASMNQVEYFGRGPAENYLDRNA
HHHHHHHHEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHCCCCCCHHHHHHCCC
GSMVGLYKSTAEELYFPYVRPQENGHHTDTRWVSLSTGKKGLLIQADNTIGFNALRNSIE
CCEEEHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHH
DFDDEEATGLPRQWSNFTPEQVANHDEAAAKNVLRRQHHINNITPRDFVEVCVDLKQQGV
HCCCCHHCCCCHHCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
AGYDSWGSRPEPAYTLPANREYNWGFTLIPLK
CCCCCCCCCCCCCEECCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MNSIKKMMLSGALGCLISGMAYADGSSPQPVKPYWQDIQVVAVNKEKPRSSFMSYADRET
CCHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHH
ALTSRFEKSPYYFLLNGTWKFFFVDSYKDLPQNITDPSVNTSSWDDITVPGNWEVQGHGV
HHHHHHCCCCEEEEEECEEEEEEEECHHHCCCCCCCCCCCCCCCCCEECCCCEEEEECCE
AIYTNHGYEFKPRNPQPPLLPEANPVGVYRRDIEIPASWDNRDIYLHIGGAKSGLYVYLN
EEEECCCEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCEEEEEC
GKEVGYSEDSKNPAEFLINKYLQPGKNVLTLKIFRWSTGSYLECQDFWRMSGIERDVFLW
CCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEHHHHHHHCCCCCEEEEE
SQPKASIQDFRVVSTLDDTYTNGIFKLAVDLKNHTQETKNLNVGYELLDAKGNLVTSEAN
CCCCCCHHHEEEEEHHHHHHCCCEEEEEEEHHHCCHHHCCCCCCEEEEECCCCEEEECCC
DIWVSPASPQTVSFEYDLKNVAPWSAEHPNLYKLLMTIKEEGKVIEVVPFNVGFRRFEMK
EEEECCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHH
QIDQVAEDGKPYTVLLFNGQPVKFKGVNIHEHNPETGHYVTEELMRKDFELMKQNNINAV
HHHHHHHCCCCEEEEEECCCCEEEECCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEE
RLCHYPQDRKFYELCDEYGLYVYDEANIESHGMYYSLKKGGTLGNNPEWLIPHMDRTMNM
EEECCCCCCHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCCCCCCCEEECCCHHHHHH
YERNKNYPSVTFWSLGNEAGNGYNFYQTYLYLKDKEINSMNRPVNYERALWEWNTDMYVP
HHHCCCCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCEECC
QYPSAEWLEEIGRKGSDRPVAPSEYSHAMGNSSGNLWDQWKAIYKYPNLQGGFIWDWVDQ
CCCCHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEHHHHC
GILEKDKNGREYYTYGGDYGVNAPSDGNFLCNGIVNPDRTPHPAMAEVKYAHQNIGFEAI
CHHHCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHCCCEEEE
DLANGLFRVTNRFYFTNLKKYMVHYSVTANNKVVRSGKVSLDIEPQASKEFTVPVGNLKP
HHHHHHHHHHHHHHHHCCEEEEEEEEEECCCEEEECCEEEEEECCCCCCEEEEECCCCCC
QAGTEYFVNFNVTTVEKEPLIPIGHEIACDQFRLPIESPKKAFKTSGPKLTVSTNGDNLS
CCCCEEEEEEEEEEECCCCCCCCCCEECCCCEECCCCCCHHHHHCCCCEEEEEECCCCCC
ASSSKVNFVFNRKTGIVTSYKVDGTEYFSEGFGIQPNFWRAPTDNDYGNGMPKRLQVWKE
CCCCEEEEEEECCCCEEEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
SSKNFNVTDATVTMDGNNAVVSVNYLLPAGNLYIVNYTIYPSGAVNVAARFTSTDMDAAQ
CCCCCEEEEEEEEECCCCEEEEEEEEECCCCEEEEEEEECCCCCEEEEEEEECCCCHHHH
TEVSEATRTATFTPGRDAARKEASKLNVPRIGVRFRLPASMNQVEYFGRGPAENYLDRNA
HHHHHHHHEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHCCCCCCHHHHHHCCC
GSMVGLYKSTAEELYFPYVRPQENGHHTDTRWVSLSTGKKGLLIQADNTIGFNALRNSIE
CCEEEHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHH
DFDDEEATGLPRQWSNFTPEQVANHDEAAAKNVLRRQHHINNITPRDFVEVCVDLKQQGV
HCCCCHHCCCCHHCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
AGYDSWGSRPEPAYTLPANREYNWGFTLIPLK
CCCCCCCCCCCCCEECCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8088532; 10360571; 9741105 [H]