Click here to switch to the map view.

The map label for this gene is bcc [H]

Identifier: 150006830

GI number: 150006830

Start: 172460

End: 172891

Strand: Reverse

Name: bcc [H]

Synonym: BDI_0161

Alternate gene names: 150006830

Gene position: 172891-172460 (Counterclockwise)

Preceding gene: 150006831

Following gene: 150006829

Centisome position: 3.59

GC content: 43.98

Gene sequence:

>432_bases
ATGAAAAGTTTTAAATATACCATTAACGGTAACGTATATAAAGTACACATCAATTCTGTAGTGGATGATATCGCAGAACT
TGAAGTAAACGGAACTCCCTACCAAGTTAAGATGGAGAAACCGGCAAAGAAACAAATGGTTACATTGAAACGCCCAGCTC
AAGCCCCGACTACGGCAAGTGGAGACCCTGTTGTTTCCCGTCCGGCGGCTTCTACGACACAAGGGGCTGTTAAGACTCCG
CTACCAGGTGTTATCTTGCAGGTTAAGTGCAACGTAGGTGATACCGTGAAGAGAGGTCAAACCTTGATTATCCTTGAGGC
TATGAAGATGGAGAACAACATCAACGCAGACCGTGACGGTAAGATTATAGAAATTAAAGTACACAAGGGAGACTCTGTGC
TAGAAGGTGCTGATCTCGTAGTAATCGGATAA

Upstream 100 bases:

>100_bases
ACTATACGTAAGGTACAACGAGCTTATTCTCCTTGGAGTTCAAAACTCTATGGCTTACGTCAAACTCCTCAAAAGTAATT
ATCTAAAAACGAACTAAAGA

Downstream 100 bases:

>100_bases
GACTATGCAAGAGAGCTTTTTAACATTCTTAGGTGAGAACTTACAACTGTTCCTTACCTATACAGGTGTATACAACGCTA
CTCCGGGACATCTCATCATG

Product: biotin carboxyl carrier protein

Products: Malonyl-CoA; malonyl-CoA; phosphate; ADP [C]

Alternate protein names: BCCP [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MKSFKYTINGNVYKVHINSVVDDIAELEVNGTPYQVKMEKPAKKQMVTLKRPAQAPTTASGDPVVSRPAASTTQGAVKTP
LPGVILQVKCNVGDTVKRGQTLIILEAMKMENNINADRDGKIIEIKVHKGDSVLEGADLVVIG

Sequences:

>Translated_143_residues
MKSFKYTINGNVYKVHINSVVDDIAELEVNGTPYQVKMEKPAKKQMVTLKRPAQAPTTASGDPVVSRPAASTTQGAVKTP
LPGVILQVKCNVGDTVKRGQTLIILEAMKMENNINADRDGKIIEIKVHKGDSVLEGADLVVIG
>Mature_143_residues
MKSFKYTINGNVYKVHINSVVDDIAELEVNGTPYQVKMEKPAKKQMVTLKRPAQAPTTASGDPVVSRPAASTTQGAVKTP
LPGVILQVKCNVGDTVKRGQTLIILEAMKMENNINADRDGKIIEIKVHKGDSVLEGADLVVIG

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl [H]

EC number: NA

Molecular weight: Translated: 15396; Mature: 15396

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFKYTINGNVYKVHINSVVDDIAELEVNGTPYQVKMEKPAKKQMVTLKRPAQAPTTAS
CCCEEEEECCCEEEEEHHHHHHHHHHEEECCCCEEEEECCCCCCCEEEEECCCCCCCCCC
GDPVVSRPAASTTQGAVKTPLPGVILQVKCNVGDTVKRGQTLIILEAMKMENNINADRDG
CCCEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCHHCCCEEEEEEEEECCCCCCCCCCC
KIIEIKVHKGDSVLEGADLVVIG
CEEEEEEECCCCEECCCCEEEEC
>Mature Secondary Structure
MKSFKYTINGNVYKVHINSVVDDIAELEVNGTPYQVKMEKPAKKQMVTLKRPAQAPTTAS
CCCEEEEECCCEEEEEHHHHHHHHHHEEECCCCEEEEECCCCCCCEEEEECCCCCCCCCC
GDPVVSRPAASTTQGAVKTPLPGVILQVKCNVGDTVKRGQTLIILEAMKMENNINADRDG
CCCEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCHHCCCEEEEEEEEECCCCCCCCCCC
KIIEIKVHKGDSVLEGADLVVIG
CEEEEEEECCCCEECCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; HCO3-; Proton; acetyl-CoA; ATP [C]

Specific reaction: acetyl-CoA = malonyl-CoA HCO3- + Proton + acetyl-CoA + ATP = malonyl-CoA + phosphate + ADP [C]

General reaction: Ligases; Forming Carbon-Carbon Bonds; acetyl-CoA carboxylase Reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8431283; 12397186 [H]