Click here to switch to the map view.

The map label for this gene is hup [H]

Identifier: 150006582

GI number: 150006582

Start: 5044252

End: 5044527

Strand: Direct

Name: hup [H]

Synonym: BVU_4102

Alternate gene names: 150006582

Gene position: 5044252-5044527 (Clockwise)

Preceding gene: 150006576

Following gene: 150006583

Centisome position: 97.7

GC content: 35.87

Gene sequence:

>276_bases
ATGACTAAAGCAGATATCGTAAACGAAATTACGAAAAATACCGGTATTGACAAGGTGACAGTGTTAACCACACTTGAGGC
TTTCATGGATACAGTAAAGGATTCATTATCTAAAGAAGAAAATGTGTACCTGCGTGGTTTTGGAAGTTTTGTAGTGAAGA
AAAGAGCTCAGAAGACTGCTCGCAACATTTCAAAGAACACTACAATCATTATTCCGGAGCACAATATTCCGGCATTTAAA
CCAGCTAAGACATTTACATTATCAGTAAAGAAATAA

Upstream 100 bases:

>100_bases
AGGAAATTTATTCTGAATATATTTCTTAAAGAGGGAGAAAAGCTATATATTTGCAGTCCAAAAAATTAAGATATAAGTAT
AACAATAATTATTTAGCGAA

Downstream 100 bases:

>100_bases
TAAACAAGAGTATTAACCCATAAAATTTGAAGCTATGCCAAGCGGAAAGAAGAAAAAAAGACACAAAATGTCTACTCACA
AGCGTAAAAAAAGACTAAGA

Product: DNA-binding protein HU

Products: NA

Alternate protein names: DNA-binding protein II; HB [H]

Number of amino acids: Translated: 91; Mature: 90

Protein sequence:

>91_residues
MTKADIVNEITKNTGIDKVTVLTTLEAFMDTVKDSLSKEENVYLRGFGSFVVKKRAQKTARNISKNTTIIIPEHNIPAFK
PAKTFTLSVKK

Sequences:

>Translated_91_residues
MTKADIVNEITKNTGIDKVTVLTTLEAFMDTVKDSLSKEENVYLRGFGSFVVKKRAQKTARNISKNTTIIIPEHNIPAFK
PAKTFTLSVKK
>Mature_90_residues
TKADIVNEITKNTGIDKVTVLTTLEAFMDTVKDSLSKEENVYLRGFGSFVVKKRAQKTARNISKNTTIIIPEHNIPAFKP
AKTFTLSVKK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

None

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 10172; Mature: 10041

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKADIVNEITKNTGIDKVTVLTTLEAFMDTVKDSLSKEENVYLRGFGSFVVKKRAQKTA
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHH
RNISKNTTIIIPEHNIPAFKPAKTFTLSVKK
HHCCCCCEEEEECCCCCCCCCCCEEEEEECC
>Mature Secondary Structure 
TKADIVNEITKNTGIDKVTVLTTLEAFMDTVKDSLSKEENVYLRGFGSFVVKKRAQKTA
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHH
RNISKNTTIIIPEHNIPAFKPAKTFTLSVKK
HHCCCCCEEEEECCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644313 [H]