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The map label for this gene is 150006520

Identifier: 150006520

GI number: 150006520

Start: 4973134

End: 4974138

Strand: Reverse

Name: 150006520

Synonym: BVU_4040

Alternate gene names: NA

Gene position: 4974138-4973134 (Counterclockwise)

Preceding gene: 150006521

Following gene: 150006519

Centisome position: 96.34

GC content: 40.3

Gene sequence:

>1005_bases
ATGATTAATCACGTTTATATAATAGCCGAAGCCGGAGTGAATCACAATGGTCGGTTGGATTTGGCTCTTCAGCTCTGTAA
TGCTGCCAAAGATGCGGGAGCTGATGCCGTGAAATTTCAGACATGGAAAACAGAGAAGATTGTTACTCGGAATGCTGAAT
TGGCTGTTTATCAGGAGAATAACATATCCGATAAGACCAAATCACAGTTTAAGATGTTGAAAGAACTTGAATTGAGCTAT
GATAATTTTGAAGTAGTGAAAAATCATTGTGATGAGATAGGTATCCAGTTCCTTTCTACTCCTGATGAAATAGATAGTCT
AGACTTTCTTTGTAATTTTAATTTGCCTTTCATCAAGCTGGGATCGGGAGATGTTACCAATATTCCTTTTCTTCGTCTTG
TTGGTAGCAGACATATTGATGTTGTCCTTTCTACAGGAATGTCGTATCTCGGTGATGTAGAGATAGCATATCGCACCTTG
ATAGAAGCAGGAGCTAAAAGTGTTTCTTTACTTCATTGTACTACTAACTATCCATGTCCCATGCATGAAGTAAATCTTCG
GGCTATACAAACTCTTAAGGATGCATTTCATTGTTCCGTAGGTTATTCAGACCATACAATGGGTGTGGAAGTACCTGTTG
CAGCTGTAGCAATGGGAGCTGAAATCATAGAGAAACATTTTACGCTTGATAAGGAAATGGACGGTCCTGACCACAAAGCC
TCCCTCAATCCCGAGGAACTCAAACAAATGGTTGTCGCCATCCGTCATATAGAACAAGCTTTAGGTGATGGCATCAAACA
GCCTAATGAGAGTGAGAAACAAATTTCAGAAGTAGTGCTCAAACGTATTGTGGCGGCTACACCAATAAAGGAAGGTGAGG
TGCTCTCGGCGGATAATATGACTGTGAAACGCAGTACCGTTGGTTTGAAAGCTTCTTTATGGGATTTGGTAAACGGGCGT
ATAGCTACCTGCAATTATGCTATAGACGAACCTATTATCATTTAA

Upstream 100 bases:

>100_bases
ACCAATGAAGTTTGCATTGGTGATTATGATGAAGGTGTGCTCATGTTGATGTATGATGATGTAGTCATAACTAAGGAAGT
TGACCTTTTAAGAGATTATC

Downstream 100 bases:

>100_bases
AAATAGACAATAGTAATGAATATACTTGTAATAATTCCTGCACGTGGTGGAAGTAAAGGAATACCTCACAAGAATGTTAA
GGAATTAAATGGAAAACCGT

Product: sialic acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MINHVYIIAEAGVNHNGRLDLALQLCNAAKDAGADAVKFQTWKTEKIVTRNAELAVYQENNISDKTKSQFKMLKELELSY
DNFEVVKNHCDEIGIQFLSTPDEIDSLDFLCNFNLPFIKLGSGDVTNIPFLRLVGSRHIDVVLSTGMSYLGDVEIAYRTL
IEAGAKSVSLLHCTTNYPCPMHEVNLRAIQTLKDAFHCSVGYSDHTMGVEVPVAAVAMGAEIIEKHFTLDKEMDGPDHKA
SLNPEELKQMVVAIRHIEQALGDGIKQPNESEKQISEVVLKRIVAATPIKEGEVLSADNMTVKRSTVGLKASLWDLVNGR
IATCNYAIDEPIII

Sequences:

>Translated_334_residues
MINHVYIIAEAGVNHNGRLDLALQLCNAAKDAGADAVKFQTWKTEKIVTRNAELAVYQENNISDKTKSQFKMLKELELSY
DNFEVVKNHCDEIGIQFLSTPDEIDSLDFLCNFNLPFIKLGSGDVTNIPFLRLVGSRHIDVVLSTGMSYLGDVEIAYRTL
IEAGAKSVSLLHCTTNYPCPMHEVNLRAIQTLKDAFHCSVGYSDHTMGVEVPVAAVAMGAEIIEKHFTLDKEMDGPDHKA
SLNPEELKQMVVAIRHIEQALGDGIKQPNESEKQISEVVLKRIVAATPIKEGEVLSADNMTVKRSTVGLKASLWDLVNGR
IATCNYAIDEPIII
>Mature_334_residues
MINHVYIIAEAGVNHNGRLDLALQLCNAAKDAGADAVKFQTWKTEKIVTRNAELAVYQENNISDKTKSQFKMLKELELSY
DNFEVVKNHCDEIGIQFLSTPDEIDSLDFLCNFNLPFIKLGSGDVTNIPFLRLVGSRHIDVVLSTGMSYLGDVEIAYRTL
IEAGAKSVSLLHCTTNYPCPMHEVNLRAIQTLKDAFHCSVGYSDHTMGVEVPVAAVAMGAEIIEKHFTLDKEMDGPDHKA
SLNPEELKQMVVAIRHIEQALGDGIKQPNESEKQISEVVLKRIVAATPIKEGEVLSADNMTVKRSTVGLKASLWDLVNGR
IATCNYAIDEPIII

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=299, Percent_Identity=37.123745819398, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI21357081, Length=361, Percent_Identity=35.1800554016621, Blast_Score=192, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 36910; Mature: 36910

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINHVYIIAEAGVNHNGRLDLALQLCNAAKDAGADAVKFQTWKTEKIVTRNAELAVYQEN
CCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHEECCCEEEEEECC
NISDKTKSQFKMLKELELSYDNFEVVKNHCDEIGIQFLSTPDEIDSLDFLCNFNLPFIKL
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEECCCCHHCCEEEEEECCCCEEEE
GSGDVTNIPFLRLVGSRHIDVVLSTGMSYLGDVEIAYRTLIEAGAKSVSLLHCTTNYPCP
CCCCCCCCCHHHHHCCCCEEHHHHCCHHHHCCHHHHHHHHHHHCCCEEEEEEEECCCCCC
MHEVNLRAIQTLKDAFHCSVGYSDHTMGVEVPVAAVAMGAEIIEKHFTLDKEMDGPDHKA
CHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SLNPEELKQMVVAIRHIEQALGDGIKQPNESEKQISEVVLKRIVAATPIKEGEVLSADNM
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCC
TVKRSTVGLKASLWDLVNGRIATCNYAIDEPIII
EEEECCCCCHHHHHHHHCCEEEEEEEECCCCCCC
>Mature Secondary Structure
MINHVYIIAEAGVNHNGRLDLALQLCNAAKDAGADAVKFQTWKTEKIVTRNAELAVYQEN
CCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHEECCCEEEEEECC
NISDKTKSQFKMLKELELSYDNFEVVKNHCDEIGIQFLSTPDEIDSLDFLCNFNLPFIKL
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEECCCCHHCCEEEEEECCCCEEEE
GSGDVTNIPFLRLVGSRHIDVVLSTGMSYLGDVEIAYRTLIEAGAKSVSLLHCTTNYPCP
CCCCCCCCCHHHHHCCCCEEHHHHCCHHHHCCHHHHHHHHHHHCCCEEEEEEEECCCCCC
MHEVNLRAIQTLKDAFHCSVGYSDHTMGVEVPVAAVAMGAEIIEKHFTLDKEMDGPDHKA
CHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SLNPEELKQMVVAIRHIEQALGDGIKQPNESEKQISEVVLKRIVAATPIKEGEVLSADNM
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCC
TVKRSTVGLKASLWDLVNGRIATCNYAIDEPIII
EEEECCCCCHHHHHHHHCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]