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The map label for this gene is ptmB [H]

Identifier: 150006519

GI number: 150006519

Start: 4972423

End: 4973118

Strand: Reverse

Name: ptmB [H]

Synonym: BVU_4039

Alternate gene names: 150006519

Gene position: 4973118-4972423 (Counterclockwise)

Preceding gene: 150006520

Following gene: 150006518

Centisome position: 96.32

GC content: 37.79

Gene sequence:

>696_bases
ATGAATATACTTGTAATAATTCCTGCACGTGGTGGAAGTAAAGGAATACCTCACAAGAATGTTAAGGAATTAAATGGAAA
ACCGTTGATATGCTATAGCATTGATGCGGCTCGTCAGCTTACCACCGATGAGAATATTTGTGTTTCTACTGATGATGATG
TCATTATCAAGGTTGTAGAGGATTATGGCTTGAAAGTTCATTTTAAACGCCCTGCAGAGTTGGCTACAGATTGTGCAGGA
ACAAATGGAGTACTGCTCCATGCTTTGGAGTTTTATGAGAAACAAGGTCGTAAATATGATGTAGTAGTTTTGTTGCAACC
CACTTCTCCTTTTCGTGAGACTAAATCATTGAAGGAGGCTGTGGCTTTGTATACTTCTGACATAGATATGGTTGTTTCGG
TGAAAGAAGCGGCAACTAATCCATATTATAATAGTTTTGAGGAGGATGCTGAAGGCTTATTGGTCATCAGCAAAGGGGAT
GGTACTATTGAACGGCGTCAGGATGCACCTAAGGTATGGGAGTTTAACGGTTCTATTTATGTGATTAATAGCACTCGCCT
TAAAGAAGTAGGTTTGTCCAAACTCAATAGAATACGTAAATATGTTATGGATGATCTTCATTCAATAGATATTGATAGTA
TGTTTGACTGGTATATGGCGGAAAAGGTAATCAGTAGTCATCTTATTGAAAATTAA

Upstream 100 bases:

>100_bases
TGGTTTGAAAGCTTCTTTATGGGATTTGGTAAACGGGCGTATAGCTACCTGCAATTATGCTATAGACGAACCTATTATCA
TTTAAAAATAGACAATAGTA

Downstream 100 bases:

>100_bases
TTTATATGAATTGCTCTCATATTATTCTCCAATCTTTCTCTATTATTGATGCCATTCGCTGCATCAATGAGATTCACAAT
GAACCACTGGTGCTCTTTGT

Product: CMP-N-acetylneuraminic acid synthetase

Products: diphosphate; CMP-N-acylneuraminate

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MNILVIIPARGGSKGIPHKNVKELNGKPLICYSIDAARQLTTDENICVSTDDDVIIKVVEDYGLKVHFKRPAELATDCAG
TNGVLLHALEFYEKQGRKYDVVVLLQPTSPFRETKSLKEAVALYTSDIDMVVSVKEAATNPYYNSFEEDAEGLLVISKGD
GTIERRQDAPKVWEFNGSIYVINSTRLKEVGLSKLNRIRKYVMDDLHSIDIDSMFDWYMAEKVISSHLIEN

Sequences:

>Translated_231_residues
MNILVIIPARGGSKGIPHKNVKELNGKPLICYSIDAARQLTTDENICVSTDDDVIIKVVEDYGLKVHFKRPAELATDCAG
TNGVLLHALEFYEKQGRKYDVVVLLQPTSPFRETKSLKEAVALYTSDIDMVVSVKEAATNPYYNSFEEDAEGLLVISKGD
GTIERRQDAPKVWEFNGSIYVINSTRLKEVGLSKLNRIRKYVMDDLHSIDIDSMFDWYMAEKVISSHLIEN
>Mature_231_residues
MNILVIIPARGGSKGIPHKNVKELNGKPLICYSIDAARQLTTDENICVSTDDDVIIKVVEDYGLKVHFKRPAELATDCAG
TNGVLLHALEFYEKQGRKYDVVVLLQPTSPFRETKSLKEAVALYTSDIDMVVSVKEAATNPYYNSFEEDAEGLLVISKGD
GTIERRQDAPKVWEFNGSIYVINSTRLKEVGLSKLNRIRKYVMDDLHSIDIDSMFDWYMAEKVISSHLIEN

Specific function: Required for biosynthesis of LAH modification in the post-translational modification of Campylobacter coli flagellin [H]

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=228, Percent_Identity=30.2631578947368, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: 2.7.7.43

Molecular weight: Translated: 25974; Mature: 25974

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILVIIPARGGSKGIPHKNVKELNGKPLICYSIDAARQLTTDENICVSTDDDVIIKVVE
CEEEEEEECCCCCCCCCCCCHHHCCCCEEEEEECCCHHHCCCCCCEEEECCCCEEEEEEE
DYGLKVHFKRPAELATDCAGTNGVLLHALEFYEKQGRKYDVVVLLQPTSPFRETKSLKEA
CCCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHH
VALYTSDIDMVVSVKEAATNPYYNSFEEDAEGLLVISKGDGTIERRQDAPKVWEFNGSIY
HHHHHCCCEEEEEEHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHCCCCCCEEEECCEEE
VINSTRLKEVGLSKLNRIRKYVMDDLHSIDIDSMFDWYMAEKVISSHLIEN
EEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNILVIIPARGGSKGIPHKNVKELNGKPLICYSIDAARQLTTDENICVSTDDDVIIKVVE
CEEEEEEECCCCCCCCCCCCHHHCCCCEEEEEECCCHHHCCCCCCEEEECCCCEEEEEEE
DYGLKVHFKRPAELATDCAGTNGVLLHALEFYEKQGRKYDVVVLLQPTSPFRETKSLKEA
CCCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHH
VALYTSDIDMVVSVKEAATNPYYNSFEEDAEGLLVISKGDGTIERRQDAPKVWEFNGSIY
HHHHHCCCEEEEEEHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHCCCCCCEEEECCEEE
VINSTRLKEVGLSKLNRIRKYVMDDLHSIDIDSMFDWYMAEKVISSHLIEN
EEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CTP; N-acylneuraminate

Specific reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8825781 [H]