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The map label for this gene is gne [H]

Identifier: 150006498

GI number: 150006498

Start: 4950496

End: 4951512

Strand: Reverse

Name: gne [H]

Synonym: BVU_4018

Alternate gene names: 150006498

Gene position: 4951512-4950496 (Counterclockwise)

Preceding gene: 150006499

Following gene: 150006497

Centisome position: 95.9

GC content: 40.51

Gene sequence:

>1017_bases
ATGAACTATTTTATAACAGGTGGGACTGGCTTTATAGGTACTCACCTGACCAACCTTCTCCAAGAATTGCACCCTGAATG
TAATGTATATAATCTTGATATAGTAGAGCCGGGTACACCGTTGCCTAGTGTGGAGGATTATAAGCCTGCATTGCGCAAGG
GGCAAAAATTGGCTTCAACATTCATTCGCTGTGATGTTCGCAAGCCTATTGTGCTTGAAGGGGTAAATGTTACGGCTGAT
GATGTTATCTTTAATTTTGCTGCCGTACATCGTACTCCGGGACATCCTGATTATGCCTACTTTGAAACAAATGTTCTTGG
TGCAGAGAATGTGACGGCTTTTGCGGAAAAGTATGGAATAAAGAAAATTGTATTCACTTCCTCCATTGCTCCATATGGTG
CAGCGGAAGAATTGAAGGAAGAAACTACAGTTCCTACTCCTAATACTCCTTATGGAATATCAAAATTGGTTGCTGAAAAG
ATTCACATGATTTGGCAAGCTAGGAATCAGGCAGAAAGACAATTGACGATCGTTCGTCCGGGTGTGGTATTCGGTAAAGG
GGAAAATGGAAACTTCACTCGTCTTTATTGGGGAATACGTGGCGGAAAATTTATATATCCCGGAAGAAAGGATACTGTAA
AGGCATGTATTTATGTGAAGGAGTTAGTCCGTTTTATGCTATATAGATTGGAACATCATGAACAGGGAGTGGAATTATAT
AACTGCACTTTTGAGCCGGCTTATACTATTGAACAGATAGTGGAAACAATGAAGAAAGTGACAGATTTGAAAAAGGTGGT
ACCATTGATACCCGCATGGGTGCTGATGCCGGTTGCCACAGTAATTGGTTGTTTGGGCGCACCCATGGGAATTTGTCCTG
CCCGTGTGAAAAAACTGATGATATCTACGAATATTTGTGGGAAAAAGCTTTCAGCTTCAGGATACAAATTCCATTATTCT
TTTGAGGAAGCGATAGCTGATTGGTATAAAGATAATGACAATCTTTATCTGAAATAA

Upstream 100 bases:

>100_bases
TTGCCGTAGTTGGGCAGAAAGATTTTCAGAGGAACGGTTTAAAAGGGAAATAAAAGAATTTGTAGAGGAGAAATATAAAG
AATTTAATAAATAATTGAGT

Downstream 100 bases:

>100_bases
ATTAAATGAGAAAAATACTTCTTATTCTTGTCGGGACATTAGTCTATATGAGTTTATACGCCCAGTTTACAACAGGAACA
ACAGGACTCCTCAATATGCC

Product: UDP-GlcNAc 4-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc 4-epimerase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MNYFITGGTGFIGTHLTNLLQELHPECNVYNLDIVEPGTPLPSVEDYKPALRKGQKLASTFIRCDVRKPIVLEGVNVTAD
DVIFNFAAVHRTPGHPDYAYFETNVLGAENVTAFAEKYGIKKIVFTSSIAPYGAAEELKEETTVPTPNTPYGISKLVAEK
IHMIWQARNQAERQLTIVRPGVVFGKGENGNFTRLYWGIRGGKFIYPGRKDTVKACIYVKELVRFMLYRLEHHEQGVELY
NCTFEPAYTIEQIVETMKKVTDLKKVVPLIPAWVLMPVATVIGCLGAPMGICPARVKKLMISTNICGKKLSASGYKFHYS
FEEAIADWYKDNDNLYLK

Sequences:

>Translated_338_residues
MNYFITGGTGFIGTHLTNLLQELHPECNVYNLDIVEPGTPLPSVEDYKPALRKGQKLASTFIRCDVRKPIVLEGVNVTAD
DVIFNFAAVHRTPGHPDYAYFETNVLGAENVTAFAEKYGIKKIVFTSSIAPYGAAEELKEETTVPTPNTPYGISKLVAEK
IHMIWQARNQAERQLTIVRPGVVFGKGENGNFTRLYWGIRGGKFIYPGRKDTVKACIYVKELVRFMLYRLEHHEQGVELY
NCTFEPAYTIEQIVETMKKVTDLKKVVPLIPAWVLMPVATVIGCLGAPMGICPARVKKLMISTNICGKKLSASGYKFHYS
FEEAIADWYKDNDNLYLK
>Mature_338_residues
MNYFITGGTGFIGTHLTNLLQELHPECNVYNLDIVEPGTPLPSVEDYKPALRKGQKLASTFIRCDVRKPIVLEGVNVTAD
DVIFNFAAVHRTPGHPDYAYFETNVLGAENVTAFAEKYGIKKIVFTSSIAPYGAAEELKEETTVPTPNTPYGISKLVAEK
IHMIWQARNQAERQLTIVRPGVVFGKGENGNFTRLYWGIRGGKFIYPGRKDTVKACIYVKELVRFMLYRLEHHEQGVELY
NCTFEPAYTIEQIVETMKKVTDLKKVVPLIPAWVLMPVATVIGCLGAPMGICPARVKKLMISTNICGKKLSASGYKFHYS
FEEAIADWYKDNDNLYLK

Specific function: Converts UDP-GlcNAc to UDP-GalNAc. Essential for O antigen synthesis [H]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.7 [H]

Molecular weight: Translated: 37970; Mature: 37970

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYFITGGTGFIGTHLTNLLQELHPECNVYNLDIVEPGTPLPSVEDYKPALRKGQKLAST
CCEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
FIRCDVRKPIVLEGVNVTADDVIFNFAAVHRTPGHPDYAYFETNVLGAENVTAFAEKYGI
HHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHCC
KKIVFTSSIAPYGAAEELKEETTVPTPNTPYGISKLVAEKIHMIWQARNQAERQLTIVRP
EEEEEECCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEC
GVVFGKGENGNFTRLYWGIRGGKFIYPGRKDTVKACIYVKELVRFMLYRLEHHEQGVELY
CEEEECCCCCCEEEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
NCTFEPAYTIEQIVETMKKVTDLKKVVPLIPAWVLMPVATVIGCLGAPMGICPARVKKLM
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
ISTNICGKKLSASGYKFHYSFEEAIADWYKDNDNLYLK
HHHCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCEEEC
>Mature Secondary Structure
MNYFITGGTGFIGTHLTNLLQELHPECNVYNLDIVEPGTPLPSVEDYKPALRKGQKLAST
CCEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
FIRCDVRKPIVLEGVNVTADDVIFNFAAVHRTPGHPDYAYFETNVLGAENVTAFAEKYGI
HHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHCC
KKIVFTSSIAPYGAAEELKEETTVPTPNTPYGISKLVAEKIHMIWQARNQAERQLTIVRP
EEEEEECCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEC
GVVFGKGENGNFTRLYWGIRGGKFIYPGRKDTVKACIYVKELVRFMLYRLEHHEQGVELY
CEEEECCCCCCEEEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
NCTFEPAYTIEQIVETMKKVTDLKKVVPLIPAWVLMPVATVIGCLGAPMGICPARVKKLM
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
ISTNICGKKLSASGYKFHYSFEEAIADWYKDNDNLYLK
HHHCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11976290; 11206551; 11258796 [H]