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The map label for this gene is fabD [H]

Identifier: 150006470

GI number: 150006470

Start: 4908435

End: 4909322

Strand: Direct

Name: fabD [H]

Synonym: BVU_3989

Alternate gene names: 150006470

Gene position: 4908435-4909322 (Clockwise)

Preceding gene: 150006469

Following gene: 150006471

Centisome position: 95.07

GC content: 48.65

Gene sequence:

>888_bases
ATGAAAGCATTTGTATTCCCCGGACAGGGAGCACAGTTTGTAGGTATGGGTAAAGACCTGTACGAAAACTCGGCTTTAGC
CAAAGAACTTTTTGAAAAAGCAAACGACATTTTAGGATACCGTATCACAGACATCATGTTTGAAGGTACTGACGAAGACT
TGCGCCAGACTAAAGTAACTCAGCCTGCCGTTTTTCTGCACTCGGTAATTTCCGCTCTTTGCATGGGTGATGATTTCAAA
CCTGAAATGACTGCCGGACACTCGCTGGGCGAATTTTCCGCATTGGTTGCAGCCGGAGCATTGTCTTTCGAAGATGGTCT
GAAACTGGTTTATGCACGTGCTATGGCTATGCAGAAAGCTTGTGAGGCACAACCCTCTACGATGGCTGCCATCATTGCAT
TGCCTGACGAAAAAGTAGAGGAAATCTGTGAAGCGATTTCTAAAGAAGGAGAAGTGGTAGTGGCTGCCAATTATAACTGC
CCGGGACAAATTGTCATCTCAGGTTCTATCGAAGGAATCAACAAGGCTTGCGAGCAAATGAAAGCTGCCGGTGCTAAACG
TGCCCTGCCGCTGAAAGTGGGAGGCGCCTTCCACTCTCCGCTGATGAACCCCGCCAAAGTGGAACTGGAAGCTGCTATCA
ACGCTACTGAAATTCATACTCCGAAATGCCCTGTATATCAGAACGTGGACGCTTTGCCTCACACAGATCCCGCTGAAATC
AAGGCAAACCTGGTAGCTCAGCTCACCGCTTCCGTACGCTGGACCCAGACAGTGAAGAATATGGTTGCCGATGGTGCCGA
TGACTTTACCGAATGCGGACCGGGTGCTGTACTGCAAGGACTGATCAAGAAAATTGATGGATCGGTCAACGCACACGGTA
TTGCTTGA

Upstream 100 bases:

>100_bases
GTACATAATGCAGCATATTAGCAAATTGCCTCATTATTATTCCGTAGTTCCGAAAGAAATAATTAACTTTGCAACGTTTT
TAAACCAAAATAGGAAAAAT

Downstream 100 bases:

>100_bases
TAAACAAAATTCAGTTATTATAAATTTTATACGGATTACCGGAATATGCTGAGTAATCCGTATTTTTTTTATGGCATTTC
ACAAAAATATTCGTAAGTTT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MKAFVFPGQGAQFVGMGKDLYENSALAKELFEKANDILGYRITDIMFEGTDEDLRQTKVTQPAVFLHSVISALCMGDDFK
PEMTAGHSLGEFSALVAAGALSFEDGLKLVYARAMAMQKACEAQPSTMAAIIALPDEKVEEICEAISKEGEVVVAANYNC
PGQIVISGSIEGINKACEQMKAAGAKRALPLKVGGAFHSPLMNPAKVELEAAINATEIHTPKCPVYQNVDALPHTDPAEI
KANLVAQLTASVRWTQTVKNMVADGADDFTECGPGAVLQGLIKKIDGSVNAHGIA

Sequences:

>Translated_295_residues
MKAFVFPGQGAQFVGMGKDLYENSALAKELFEKANDILGYRITDIMFEGTDEDLRQTKVTQPAVFLHSVISALCMGDDFK
PEMTAGHSLGEFSALVAAGALSFEDGLKLVYARAMAMQKACEAQPSTMAAIIALPDEKVEEICEAISKEGEVVVAANYNC
PGQIVISGSIEGINKACEQMKAAGAKRALPLKVGGAFHSPLMNPAKVELEAAINATEIHTPKCPVYQNVDALPHTDPAEI
KANLVAQLTASVRWTQTVKNMVADGADDFTECGPGAVLQGLIKKIDGSVNAHGIA
>Mature_295_residues
MKAFVFPGQGAQFVGMGKDLYENSALAKELFEKANDILGYRITDIMFEGTDEDLRQTKVTQPAVFLHSVISALCMGDDFK
PEMTAGHSLGEFSALVAAGALSFEDGLKLVYARAMAMQKACEAQPSTMAAIIALPDEKVEEICEAISKEGEVVVAANYNC
PGQIVISGSIEGINKACEQMKAAGAKRALPLKVGGAFHSPLMNPAKVELEAAINATEIHTPKCPVYQNVDALPHTDPAEI
KANLVAQLTASVRWTQTVKNMVADGADDFTECGPGAVLQGLIKKIDGSVNAHGIA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=300, Percent_Identity=35.6666666666667, Blast_Score=161, Evalue=6e-40,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=39.4495412844037, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI41872631, Length=296, Percent_Identity=26.0135135135135, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787334, Length=294, Percent_Identity=42.1768707482993, Blast_Score=190, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI71984332, Length=291, Percent_Identity=31.2714776632302, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17550940, Length=292, Percent_Identity=27.0547945205479, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=35.2159468438538, Blast_Score=159, Evalue=2e-39,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31270; Mature: 31270

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFVFPGQGAQFVGMGKDLYENSALAKELFEKANDILGYRITDIMFEGTDEDLRQTKVT
CCEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEHEEECCCCHHHHHHHCC
QPAVFLHSVISALCMGDDFKPEMTAGHSLGEFSALVAAGALSFEDGLKLVYARAMAMQKA
CHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
CEAQPSTMAAIIALPDEKVEEICEAISKEGEVVVAANYNCPGQIVISGSIEGINKACEQM
HCCCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCHHHHHHHHHH
KAAGAKRALPLKVGGAFHSPLMNPAKVELEAAINATEIHTPKCPVYQNVDALPHTDPAEI
HHCCCCCCCEEEECCCHHCCCCCCHHEEEEHHCCHHCCCCCCCCCCCCCCCCCCCCHHHH
KANLVAQLTASVRWTQTVKNMVADGADDFTECGPGAVLQGLIKKIDGSVNAHGIA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKAFVFPGQGAQFVGMGKDLYENSALAKELFEKANDILGYRITDIMFEGTDEDLRQTKVT
CCEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEHEEECCCCHHHHHHHCC
QPAVFLHSVISALCMGDDFKPEMTAGHSLGEFSALVAAGALSFEDGLKLVYARAMAMQKA
CHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
CEAQPSTMAAIIALPDEKVEEICEAISKEGEVVVAANYNCPGQIVISGSIEGINKACEQM
HCCCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCHHHHHHHHHH
KAAGAKRALPLKVGGAFHSPLMNPAKVELEAAINATEIHTPKCPVYQNVDALPHTDPAEI
HHCCCCCCCEEEECCCHHCCCCCCHHEEEEHHCCHHCCCCCCCCCCCCCCCCCCCCHHHH
KANLVAQLTASVRWTQTVKNMVADGADDFTECGPGAVLQGLIKKIDGSVNAHGIA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]