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The map label for this gene is yycF [H]

Identifier: 150006464

GI number: 150006464

Start: 4901856

End: 4902212

Strand: Reverse

Name: yycF [H]

Synonym: BVU_3983

Alternate gene names: 150006464

Gene position: 4902212-4901856 (Counterclockwise)

Preceding gene: 150006467

Following gene: 150006455

Centisome position: 94.95

GC content: 42.58

Gene sequence:

>357_bases
ATGAAAAAGATTTTGGTAGCTGAAGATACGGAAAGTAATTATCTCTTATTATCTATAATTTTAAGAAAGGAGTATGAAGT
TCACCGTGCCCATGATGGGCAGGAGGCTATTGAGAAATTTGAGAGTTGCCGGCCCGATATGATTTTGATGGATATAAAGA
TGCCTGTTATGGACGGTTTGGAAGCTACCAGAAGAATTCGTCTGAAGGGAGGGACACTTCCCATCATAGCTCTTACCGCC
AATGCATACGACAGTGACCGTGACAAGGCTTTTGAAGCCGGATGTGACGATTATATGGCCAAGCCGATCATGGCTCCCGC
TTTGCGTGAGATGATAAAAAAGTATTTTGGTGAGTAA

Upstream 100 bases:

>100_bases
TAGATGCGTGATATTTGTTACTGACAGCAAATATACAAAAAAAATATTGTTTATATCATTTTATATCGTAATTTTGCAAG
GTAATCAATGAAAAGAAGAA

Downstream 100 bases:

>100_bases
ATATTATGCCCTGCGGGACTTTTCCCATGTTCCGCCGGCATGTCTCTTCAAATAGAAGAAACCTTTTATCACATTGATGT
TCATGAACAGGAAATAGTAG

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MKKILVAEDTESNYLLLSIILRKEYEVHRAHDGQEAIEKFESCRPDMILMDIKMPVMDGLEATRRIRLKGGTLPIIALTA
NAYDSDRDKAFEAGCDDYMAKPIMAPALREMIKKYFGE

Sequences:

>Translated_118_residues
MKKILVAEDTESNYLLLSIILRKEYEVHRAHDGQEAIEKFESCRPDMILMDIKMPVMDGLEATRRIRLKGGTLPIIALTA
NAYDSDRDKAFEAGCDDYMAKPIMAPALREMIKKYFGE
>Mature_118_residues
MKKILVAEDTESNYLLLSIILRKEYEVHRAHDGQEAIEKFESCRPDMILMDIKMPVMDGLEATRRIRLKGGTLPIIALTA
NAYDSDRDKAFEAGCDDYMAKPIMAPALREMIKKYFGE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=113, Percent_Identity=35.3982300884956, Blast_Score=74, Evalue=3e-15,
Organism=Escherichia coli, GI1788713, Length=112, Percent_Identity=36.6071428571429, Blast_Score=70, Evalue=4e-14,
Organism=Escherichia coli, GI48994928, Length=117, Percent_Identity=37.6068376068376, Blast_Score=69, Evalue=7e-14,
Organism=Escherichia coli, GI1788550, Length=103, Percent_Identity=33.9805825242718, Blast_Score=66, Evalue=7e-13,
Organism=Escherichia coli, GI1789149, Length=115, Percent_Identity=33.0434782608696, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1788191, Length=93, Percent_Identity=35.4838709677419, Blast_Score=61, Evalue=2e-11,
Organism=Escherichia coli, GI1786911, Length=104, Percent_Identity=31.7307692307692, Blast_Score=60, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=121, Percent_Identity=38.0165289256198, Blast_Score=76, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322000, Length=114, Percent_Identity=35.9649122807018, Blast_Score=67, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6323034, Length=141, Percent_Identity=29.7872340425532, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 13485; Mature: 13485

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
6.8 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
6.8 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILVAEDTESNYLLLSIILRKEYEVHRAHDGQEAIEKFESCRPDMILMDIKMPVMDGL
CCCEEEEECCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCHHCCH
EATRRIRLKGGTLPIIALTANAYDSDRDKAFEAGCDDYMAKPIMAPALREMIKKYFGE
HHHHEEEECCCCEEEEEEEECCCCCCCHHHHHCCCHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKKILVAEDTESNYLLLSIILRKEYEVHRAHDGQEAIEKFESCRPDMILMDIKMPVMDGL
CCCEEEEECCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCHHCCH
EATRRIRLKGGTLPIIALTANAYDSDRDKAFEAGCDDYMAKPIMAPALREMIKKYFGE
HHHHEEEECCCCEEEEEEEECCCCCCCHHHHHCCCHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Phosphotransferases with a nitrogenous group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]