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The map label for this gene is galE [H]

Identifier: 150006364

GI number: 150006364

Start: 4788652

End: 4789686

Strand: Reverse

Name: galE [H]

Synonym: BVU_3883

Alternate gene names: 150006364

Gene position: 4789686-4788652 (Counterclockwise)

Preceding gene: 150006365

Following gene: 150006363

Centisome position: 92.77

GC content: 41.55

Gene sequence:

>1035_bases
ATGAAAGAAAGAATTTTAGTAACAGGAGGAACCGGCTACATCGGTTCTCATACGGTAGTAGAGCTGCAAAATAGCGGTTA
CGACGTAGTGATTGTGGACAATTTGTCCAACTCAAGCGCCGATGTGGTAGATAATATAGAAAAGGTTTCAGGAATCCGTC
CTGCATTTGAAAAGTTGGATTGCTTGGATCTTGAGGGAATGGATAAGCTGTTTACTAAATATCCGGGTATAAAAGGTATT
ATTCATTTTGCGGCTAGCAAGGCTGTGGGTGAATCGGTACAAAAACCGTTGTTGTATTATCGCAATAACTTGGTTTCATT
GATTAACCTGTTGGAGTTAATGCCGAAACATGGAGTAGAAGGTATTATTTTTTCATCATCATGTACGGTGTATGGTCAGC
CCGATGTTCTTCCTGTAACGGAAGAGGCTCCGATTAAGAAGGCTGAGTCTCCGTACGGTAATACAAAACAGATCAATGAA
GAAATTATTCGTGATACAGTTGCTTCGGGATCGCCTATCAATGCTATTATGTTGCGTTACTTTAATCCTATTGGCGCACA
TCCCACTGCATTAATAGGTGAATTACCTAATGGGGTTCCACAAAATTTGCTACCTTATGTTACTCAGACAGCGATGGGTA
TTCGTGAAAAACTGAGTGTGTTCGGGGATGATTATGATACACCGGACGGTTCTTGCATCCGTGACTATATATATGTAGTG
GATTTGGCGAAGGCTCACGTTATCGCAATGGATCGCATTTTGAATAACAAGCAGAAGGAGAAGGTGGAAGTCTTTAATAT
TGGAACGGGTAAAGGTGTTTCTGTATTGGAACTGATCAATACGTTTGAAAAAGCTACCGGTGTGAAACTTAATTATCAGA
TCGTGGGTCGTCGTGCCGGAGATATTGAGAAGGTATGGGCTAATCCTGATTTTGCTAATAAGGAGTTGGGATGGAAGGCA
GAAGCCAATTTGGAGGACACTCTACGTTCGGCTTGGAACTGGCAGCTGAAACTAAGAGAAAGAGGAATTCAATAA

Upstream 100 bases:

>100_bases
AGATACAAGTCCTGCTTCGTATCAATGATATGATACGAAAAGGGATCTACCCGTCGAAGTTGTTTTGAACCTATTAGAAA
ACGACAGAATATTAAGTATT

Downstream 100 bases:

>100_bases
GAATTAAGATATTTTTAGAAAGACCGATGAACAAAGGACGCTAGTGTGGCGTTTTATAGATGCAAATAACCTGAAACCCC
TCTTGGATATGTGAATACCT

Product: putative UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKERILVTGGTGYIGSHTVVELQNSGYDVVIVDNLSNSSADVVDNIEKVSGIRPAFEKLDCLDLEGMDKLFTKYPGIKGI
IHFAASKAVGESVQKPLLYYRNNLVSLINLLELMPKHGVEGIIFSSSCTVYGQPDVLPVTEEAPIKKAESPYGNTKQINE
EIIRDTVASGSPINAIMLRYFNPIGAHPTALIGELPNGVPQNLLPYVTQTAMGIREKLSVFGDDYDTPDGSCIRDYIYVV
DLAKAHVIAMDRILNNKQKEKVEVFNIGTGKGVSVLELINTFEKATGVKLNYQIVGRRAGDIEKVWANPDFANKELGWKA
EANLEDTLRSAWNWQLKLRERGIQ

Sequences:

>Translated_344_residues
MKERILVTGGTGYIGSHTVVELQNSGYDVVIVDNLSNSSADVVDNIEKVSGIRPAFEKLDCLDLEGMDKLFTKYPGIKGI
IHFAASKAVGESVQKPLLYYRNNLVSLINLLELMPKHGVEGIIFSSSCTVYGQPDVLPVTEEAPIKKAESPYGNTKQINE
EIIRDTVASGSPINAIMLRYFNPIGAHPTALIGELPNGVPQNLLPYVTQTAMGIREKLSVFGDDYDTPDGSCIRDYIYVV
DLAKAHVIAMDRILNNKQKEKVEVFNIGTGKGVSVLELINTFEKATGVKLNYQIVGRRAGDIEKVWANPDFANKELGWKA
EANLEDTLRSAWNWQLKLRERGIQ
>Mature_344_residues
MKERILVTGGTGYIGSHTVVELQNSGYDVVIVDNLSNSSADVVDNIEKVSGIRPAFEKLDCLDLEGMDKLFTKYPGIKGI
IHFAASKAVGESVQKPLLYYRNNLVSLINLLELMPKHGVEGIIFSSSCTVYGQPDVLPVTEEAPIKKAESPYGNTKQINE
EIIRDTVASGSPINAIMLRYFNPIGAHPTALIGELPNGVPQNLLPYVTQTAMGIREKLSVFGDDYDTPDGSCIRDYIYVV
DLAKAHVIAMDRILNNKQKEKVEVFNIGTGKGVSVLELINTFEKATGVKLNYQIVGRRAGDIEKVWANPDFANKELGWKA
EANLEDTLRSAWNWQLKLRERGIQ

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=48.6803519061584, Blast_Score=346, Evalue=2e-95,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=48.6803519061584, Blast_Score=346, Evalue=2e-95,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=48.6803519061584, Blast_Score=346, Evalue=2e-95,
Organism=Homo sapiens, GI42516563, Length=338, Percent_Identity=23.3727810650888, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=44.6107784431138, Blast_Score=307, Evalue=7e-85,
Organism=Escherichia coli, GI1788353, Length=368, Percent_Identity=27.1739130434783, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI48994969, Length=359, Percent_Identity=25.0696378830084, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=341, Percent_Identity=45.4545454545455, Blast_Score=305, Evalue=2e-83,
Organism=Caenorhabditis elegans, GI71982038, Length=343, Percent_Identity=44.8979591836735, Blast_Score=303, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI17568069, Length=355, Percent_Identity=23.943661971831, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=336, Percent_Identity=49.1071428571429, Blast_Score=324, Evalue=2e-89,
Organism=Drosophila melanogaster, GI19923002, Length=337, Percent_Identity=46.2908011869436, Blast_Score=318, Evalue=4e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37983; Mature: 37983

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERILVTGGTGYIGSHTVVELQNSGYDVVIVDNLSNSSADVVDNIEKVSGIRPAFEKLD
CCCCEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHCC
CLDLEGMDKLFTKYPGIKGIIHFAASKAVGESVQKPLLYYRNNLVSLINLLELMPKHGVE
CCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GIIFSSSCTVYGQPDVLPVTEEAPIKKAESPYGNTKQINEEIIRDTVASGSPINAIMLRY
EEEEECCEEEECCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
FNPIGAHPTALIGELPNGVPQNLLPYVTQTAMGIREKLSVFGDDYDTPDGSCIRDYIYVV
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
DLAKAHVIAMDRILNNKQKEKVEVFNIGTGKGVSVLELINTFEKATGVKLNYQIVGRRAG
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCC
DIEKVWANPDFANKELGWKAEANLEDTLRSAWNWQLKLRERGIQ
CCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHCEEEEECCCCCC
>Mature Secondary Structure
MKERILVTGGTGYIGSHTVVELQNSGYDVVIVDNLSNSSADVVDNIEKVSGIRPAFEKLD
CCCCEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHCC
CLDLEGMDKLFTKYPGIKGIIHFAASKAVGESVQKPLLYYRNNLVSLINLLELMPKHGVE
CCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GIIFSSSCTVYGQPDVLPVTEEAPIKKAESPYGNTKQINEEIIRDTVASGSPINAIMLRY
EEEEECCEEEECCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
FNPIGAHPTALIGELPNGVPQNLLPYVTQTAMGIREKLSVFGDDYDTPDGSCIRDYIYVV
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
DLAKAHVIAMDRILNNKQKEKVEVFNIGTGKGVSVLELINTFEKATGVKLNYQIVGRRAG
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCC
DIEKVWANPDFANKELGWKAEANLEDTLRSAWNWQLKLRERGIQ
CCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]