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The map label for this gene is lolC [H]

Identifier: 150006345

GI number: 150006345

Start: 4764430

End: 4765674

Strand: Reverse

Name: lolC [H]

Synonym: BVU_3864

Alternate gene names: 150006345

Gene position: 4765674-4764430 (Counterclockwise)

Preceding gene: 150006346

Following gene: 150006340

Centisome position: 92.3

GC content: 46.75

Gene sequence:

>1245_bases
ATGGACTGGAAGCTCTTTATTGCCAGACGCATCTATCGCAGCAATGAGGGTGGAAAAGAGGTGTCCAAGCCTGCCGTCCG
CATTGCTATGCTGGGCATAGCCATCGGGCTGGCCGTCATGATTGTGTCGGTAGCGGTGGTGATCGGTTTCAAACATGAGG
TACGCGACAAGGTGGTAGGCTTGGGGTCCGATATCGTAATAACTAACTTCGACTCCCAGCAATCTTATCAGACGGTTCCC
ATCGTTGCCAACGACAGTTTGCTCCATCTGTTGAAAACACTGGAAGGAGTGAAGCACGTGCAGCGCTATTCCACCAAGCC
GGGAATGATTATGACAGACGACAGCTTTCAGGGAATGGTACTGAAAGGTGTTTCTCATGAATACGACTGGAGGTTTTTAA
AGAATCATTTGCAGGAAGGGGAAATTCCTGTTTTCTCGGATACTGCCTCTACCAATAAGGTATTGGTGTCCCGCACTATT
GCCGACAAGCTTCATCTGAAACTGGGTGATAAAATCTATACCTATTATATAGAGGATAATGTGCGCGCCCGCCGTCTTAC
TGTCGCCGGCATCTATCAGACCAATTTTTCCGCATACGATGATTTGTTTCTGATAACCGACTTATATACGGTGAACCGTT
TGAATGGCTGGCAGAAAGGGCAGGTGAGTGGTATGGAACTGGAAGTGAATGAGTATAGCCGGTTGGAGCCGGTGAAGGAG
GAAATCCGTGCACGGGTGGATACGCAGGTGGATGCATACGGAGGTACTTACTATACTCAGACGGTGGAGGAAGTCAATCC
TCAGATATTTGCATGGCTGGATTTGCTGGATATGAATGTGTGGGTTATCTTGTTTCTCATGACGGGGGTGGCCGGATTCA
CCATGATATCCGGTTTGCTGATTATCATTCTGGAGCGTACCAATATGATCGGGGTGCTGAAAGCATTGGGAGCTGATAAT
TTTGCTATCCGTAAGATATTCCTCAGTTTTTCTGTATTCTTGATAGGCAGGGGGATGCTATGGGGAAATATCATCGGGGT
GGCATTATGCTTTATTCAATCTCAATTTCATCTTTTCAAACTGGACCCTGCCACTTATTATGTAGATCGTGTTCCTGTTG
AATTCAACATTTGGATTTATTTGTTGCTGAATGTCTGTACTTTGCTGGTGTCGGTGCTGATGCTTGTCGGGCCGTCATTT
CTGGTGACGCGTATTCATCCGGCAAAATCTATTCGGTTTGAATGA

Upstream 100 bases:

>100_bases
GTGCGTATTGCCTACGTGTTGAAGAAAGAGGATTTGGTCCGTGCGTTGTTCGTACTGCGTAAGGCATTGGAAGCATATCC
CGGAAGGGTAGAAGACTGAT

Downstream 100 bases:

>100_bases
GAAGATTCTCTTTCTGCGTTTTCCGTATATCCGGTATTAATCCTTTTTTCCTATAATGCTAAGGTCTTTTTCCCTTATGA
TTAAGTCTTTTTATGCGGTA

Product: ABC transporter permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MDWKLFIARRIYRSNEGGKEVSKPAVRIAMLGIAIGLAVMIVSVAVVIGFKHEVRDKVVGLGSDIVITNFDSQQSYQTVP
IVANDSLLHLLKTLEGVKHVQRYSTKPGMIMTDDSFQGMVLKGVSHEYDWRFLKNHLQEGEIPVFSDTASTNKVLVSRTI
ADKLHLKLGDKIYTYYIEDNVRARRLTVAGIYQTNFSAYDDLFLITDLYTVNRLNGWQKGQVSGMELEVNEYSRLEPVKE
EIRARVDTQVDAYGGTYYTQTVEEVNPQIFAWLDLLDMNVWVILFLMTGVAGFTMISGLLIIILERTNMIGVLKALGADN
FAIRKIFLSFSVFLIGRGMLWGNIIGVALCFIQSQFHLFKLDPATYYVDRVPVEFNIWIYLLLNVCTLLVSVLMLVGPSF
LVTRIHPAKSIRFE

Sequences:

>Translated_414_residues
MDWKLFIARRIYRSNEGGKEVSKPAVRIAMLGIAIGLAVMIVSVAVVIGFKHEVRDKVVGLGSDIVITNFDSQQSYQTVP
IVANDSLLHLLKTLEGVKHVQRYSTKPGMIMTDDSFQGMVLKGVSHEYDWRFLKNHLQEGEIPVFSDTASTNKVLVSRTI
ADKLHLKLGDKIYTYYIEDNVRARRLTVAGIYQTNFSAYDDLFLITDLYTVNRLNGWQKGQVSGMELEVNEYSRLEPVKE
EIRARVDTQVDAYGGTYYTQTVEEVNPQIFAWLDLLDMNVWVILFLMTGVAGFTMISGLLIIILERTNMIGVLKALGADN
FAIRKIFLSFSVFLIGRGMLWGNIIGVALCFIQSQFHLFKLDPATYYVDRVPVEFNIWIYLLLNVCTLLVSVLMLVGPSF
LVTRIHPAKSIRFE
>Mature_414_residues
MDWKLFIARRIYRSNEGGKEVSKPAVRIAMLGIAIGLAVMIVSVAVVIGFKHEVRDKVVGLGSDIVITNFDSQQSYQTVP
IVANDSLLHLLKTLEGVKHVQRYSTKPGMIMTDDSFQGMVLKGVSHEYDWRFLKNHLQEGEIPVFSDTASTNKVLVSRTI
ADKLHLKLGDKIYTYYIEDNVRARRLTVAGIYQTNFSAYDDLFLITDLYTVNRLNGWQKGQVSGMELEVNEYSRLEPVKE
EIRARVDTQVDAYGGTYYTQTVEEVNPQIFAWLDLLDMNVWVILFLMTGVAGFTMISGLLIIILERTNMIGVLKALGADN
FAIRKIFLSFSVFLIGRGMLWGNIIGVALCFIQSQFHLFKLDPATYYVDRVPVEFNIWIYLLLNVCTLLVSVLMLVGPSF
LVTRIHPAKSIRFE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=369, Percent_Identity=22.4932249322493, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46917; Mature: 46917

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWKLFIARRIYRSNEGGKEVSKPAVRIAMLGIAIGLAVMIVSVAVVIGFKHEVRDKVVG
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
LGSDIVITNFDSQQSYQTVPIVANDSLLHLLKTLEGVKHVQRYSTKPGMIMTDDSFQGMV
CCCCEEEEECCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEE
LKGVSHEYDWRFLKNHLQEGEIPVFSDTASTNKVLVSRTIADKLHLKLGDKIYTYYIEDN
EECCCCCCCHHHHHHHHCCCCCCEEECCCCCCEEEEEHHHHHHHHHEECCEEEEEEEECC
VRARRLTVAGIYQTNFSAYDDLFLITDLYTVNRLNGWQKGQVSGMELEVNEYSRLEPVKE
CEEEEEEEEEEEECCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCEEEEECCHHCCCHHHH
EIRARVDTQVDAYGGTYYTQTVEEVNPQIFAWLDLLDMNVWVILFLMTGVAGFTMISGLL
HHHHHHCCEEECCCCEEHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIILERTNMIGVLKALGADNFAIRKIFLSFSVFLIGRGMLWGNIIGVALCFIQSQFHLFK
EEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEE
LDPATYYVDRVPVEFNIWIYLLLNVCTLLVSVLMLVGPSFLVTRIHPAKSIRFE
ECCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCC
>Mature Secondary Structure
MDWKLFIARRIYRSNEGGKEVSKPAVRIAMLGIAIGLAVMIVSVAVVIGFKHEVRDKVVG
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
LGSDIVITNFDSQQSYQTVPIVANDSLLHLLKTLEGVKHVQRYSTKPGMIMTDDSFQGMV
CCCCEEEEECCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEE
LKGVSHEYDWRFLKNHLQEGEIPVFSDTASTNKVLVSRTIADKLHLKLGDKIYTYYIEDN
EECCCCCCCHHHHHHHHCCCCCCEEECCCCCCEEEEEHHHHHHHHHEECCEEEEEEEECC
VRARRLTVAGIYQTNFSAYDDLFLITDLYTVNRLNGWQKGQVSGMELEVNEYSRLEPVKE
CEEEEEEEEEEEECCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCEEEEECCHHCCCHHHH
EIRARVDTQVDAYGGTYYTQTVEEVNPQIFAWLDLLDMNVWVILFLMTGVAGFTMISGLL
HHHHHHCCEEECCCCEEHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIILERTNMIGVLKALGADNFAIRKIFLSFSVFLIGRGMLWGNIIGVALCFIQSQFHLFK
EEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEE
LDPATYYVDRVPVEFNIWIYLLLNVCTLLVSVLMLVGPSFLVTRIHPAKSIRFE
ECCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]