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The map label for this gene is pgcA [H]

Identifier: 150006293

GI number: 150006293

Start: 4700315

End: 4702060

Strand: Reverse

Name: pgcA [H]

Synonym: BVU_3804

Alternate gene names: 150006293

Gene position: 4702060-4700315 (Counterclockwise)

Preceding gene: 150006294

Following gene: 150006292

Centisome position: 91.07

GC content: 40.95

Gene sequence:

>1746_bases
ATGGAAAATGAAGAATTGATAAAGCAAGTGACAGAGAAAGCAGAGAAATGGTTAACACCTGCTTATGATGCCGAAACACA
GGCTGAAATTAAGAAAATGTTGGCGAATCCCGATAAGACTGATTTGATTGAAGCATTTTATAAAGATTTGGAGTTTGGGA
CAGGTGGTTTGCGTGGTATTATGGGCGTGGGCAGTAACCGTATGAATATTTATACGGTAGGTGCTGCTACTCAAGGTTTG
TCCAATTATCTAAATAAAAATTTTAAAGATCTCGATCAGATATCTGTTGTGGTAGGTCATGATTGCCGTAACAACAGCCG
TTTGTTTGCGGAAATTTCTGCCAATATCTTTTCTGCGAACGGTATTAAAGTATATTTGTTTGAAGATATGCGTCCTACTC
CTGAAATGTCATTTGCTATCCGTCATTTCGGTTGCCAGAGCGGTATCAATATTACTGCCTCTCATAATCCGAGAGAATAC
AATGGTTACAAGGCTTATTGGGATGATGGTGCACAAGTATTGGCTCCGCACGATAAGGGTATCATTGATGAGGTGAACAA
GATTTCATCGGCTACTGACATCAAGTTTGAAGGTAACAAGGATCTGATTCAGATTGTGGGCGAAGAGGTAGACAGCGTCT
ATTTGAATAAAGTGAAAACAATTTCTATTGATCCTGAAGTGATCAAGCGTCAGAAGGATTTGAAAATTGTGTATACTCCG
ATTCATGGTACAGGTATGATGTTGATTCCGCGTGCATTGAAGCAATGGGGATTTGAAAATGTACATACCGTGCCTGAACA
AATGGTGAAGAGTGGCGATTTTCCGACTGTTGTCTCTCCGAATCCGGAAAATGCCGAGGCTTTGTCTATGGCTATTGATT
TGGCTAAGAAAATAGACGCTGACATTGTAATGGCTAGCGATCCGGATGCTGACCGCGTAGGTATGGCTTGTAAAAATGAC
AAAGGAGAATGGGTGCTGATCAATGGTAACCAAACCTGTTTGCTGTTCTTGTATTATATAATAAAGAACCGTATTGCGAT
GGGTAAGATGAAGGATGATGATTTCATTGTGAAGACTATCGTTACTACGGAACTGATTAAATCTGTCGCAGACAAGAATC
ACATCGAAATGTTGGATTGCTATACCGGATTCAAGTGGATTGCACGTGAAATCCGTTTGCGTGAAGGCAAACAGCAATAC
ATCGGAGGTGGTGAAGAAAGCTACGGATTCCTGGCCGAAGACTTTGTCCGTGATAAAGATGCTGTTTCTGCTTGTACATT
GTTGGCGGAGATTTGTGCTTGGGCAAAAGACCAGGGCAAGACCTTGTTCGAAGTTTTGCTTGATATTTATGTGGAGTATG
GTTTCTCAAAAGAAACTACTGTGAATGTTGTGAAACCAGGAAAGAGCGGGGCAGAAGAGATTAAGGCAATGATGGAAAAC
TTCCGTTCTAATCCTCCGAGAGAAATAGGCGGTTCTAAGGTTGTTCTTGTCAAGGACTTTAAAACTTTGAAGGTGACAGA
TGGTAACGGGAATATAACAGAAATAGATATGCCGGAGGCTAGTAACGTATTGCAATATTTTACGGAAGATGGAACTAAGA
TTTCAGTTCGCCCGTCAGGAACAGAACCTAAAATCAAATTTTATGTGGAAGTAAAAGGTGAAATGGGTTGCCACAAATGT
TTCGATGCTGCTAATGCAGCTGCTGAGGAAAAGGTGGAAGCCGTAAGAAAATCACTGGGAATTTAA

Upstream 100 bases:

>100_bases
TTCTTCTTTCAAATTTCTAGGATTTTTAATTTAATTCTTTTACATTTGTCAAGACGTAAAAATCGGATGTAATTATAAAC
CTTATAAATAACAAAAAATT

Downstream 100 bases:

>100_bases
TCGAGTATAAGCATCGGGCGAAAGTCTGAGAGAATATTCATAAATAAAAGAAGGGGTGGTGGAGATGTATTTCTCTATCC
CCCTTTTCTTTTATTTCCGT

Product: putative phosphoglucomutase

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MENEELIKQVTEKAEKWLTPAYDAETQAEIKKMLANPDKTDLIEAFYKDLEFGTGGLRGIMGVGSNRMNIYTVGAATQGL
SNYLNKNFKDLDQISVVVGHDCRNNSRLFAEISANIFSANGIKVYLFEDMRPTPEMSFAIRHFGCQSGINITASHNPREY
NGYKAYWDDGAQVLAPHDKGIIDEVNKISSATDIKFEGNKDLIQIVGEEVDSVYLNKVKTISIDPEVIKRQKDLKIVYTP
IHGTGMMLIPRALKQWGFENVHTVPEQMVKSGDFPTVVSPNPENAEALSMAIDLAKKIDADIVMASDPDADRVGMACKND
KGEWVLINGNQTCLLFLYYIIKNRIAMGKMKDDDFIVKTIVTTELIKSVADKNHIEMLDCYTGFKWIAREIRLREGKQQY
IGGGEESYGFLAEDFVRDKDAVSACTLLAEICAWAKDQGKTLFEVLLDIYVEYGFSKETTVNVVKPGKSGAEEIKAMMEN
FRSNPPREIGGSKVVLVKDFKTLKVTDGNGNITEIDMPEASNVLQYFTEDGTKISVRPSGTEPKIKFYVEVKGEMGCHKC
FDAANAAAEEKVEAVRKSLGI

Sequences:

>Translated_581_residues
MENEELIKQVTEKAEKWLTPAYDAETQAEIKKMLANPDKTDLIEAFYKDLEFGTGGLRGIMGVGSNRMNIYTVGAATQGL
SNYLNKNFKDLDQISVVVGHDCRNNSRLFAEISANIFSANGIKVYLFEDMRPTPEMSFAIRHFGCQSGINITASHNPREY
NGYKAYWDDGAQVLAPHDKGIIDEVNKISSATDIKFEGNKDLIQIVGEEVDSVYLNKVKTISIDPEVIKRQKDLKIVYTP
IHGTGMMLIPRALKQWGFENVHTVPEQMVKSGDFPTVVSPNPENAEALSMAIDLAKKIDADIVMASDPDADRVGMACKND
KGEWVLINGNQTCLLFLYYIIKNRIAMGKMKDDDFIVKTIVTTELIKSVADKNHIEMLDCYTGFKWIAREIRLREGKQQY
IGGGEESYGFLAEDFVRDKDAVSACTLLAEICAWAKDQGKTLFEVLLDIYVEYGFSKETTVNVVKPGKSGAEEIKAMMEN
FRSNPPREIGGSKVVLVKDFKTLKVTDGNGNITEIDMPEASNVLQYFTEDGTKISVRPSGTEPKIKFYVEVKGEMGCHKC
FDAANAAAEEKVEAVRKSLGI
>Mature_581_residues
MENEELIKQVTEKAEKWLTPAYDAETQAEIKKMLANPDKTDLIEAFYKDLEFGTGGLRGIMGVGSNRMNIYTVGAATQGL
SNYLNKNFKDLDQISVVVGHDCRNNSRLFAEISANIFSANGIKVYLFEDMRPTPEMSFAIRHFGCQSGINITASHNPREY
NGYKAYWDDGAQVLAPHDKGIIDEVNKISSATDIKFEGNKDLIQIVGEEVDSVYLNKVKTISIDPEVIKRQKDLKIVYTP
IHGTGMMLIPRALKQWGFENVHTVPEQMVKSGDFPTVVSPNPENAEALSMAIDLAKKIDADIVMASDPDADRVGMACKND
KGEWVLINGNQTCLLFLYYIIKNRIAMGKMKDDDFIVKTIVTTELIKSVADKNHIEMLDCYTGFKWIAREIRLREGKQQY
IGGGEESYGFLAEDFVRDKDAVSACTLLAEICAWAKDQGKTLFEVLLDIYVEYGFSKETTVNVVKPGKSGAEEIKAMMEN
FRSNPPREIGGSKVVLVKDFKTLKVTDGNGNITEIDMPEASNVLQYFTEDGTKISVRPSGTEPKIKFYVEVKGEMGCHKC
FDAANAAAEEKVEAVRKSLGI

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=572, Percent_Identity=32.8671328671329, Blast_Score=315, Evalue=7e-86,
Organism=Homo sapiens, GI31377548, Length=559, Percent_Identity=32.2003577817531, Blast_Score=276, Evalue=5e-74,
Organism=Escherichia coli, GI1786904, Length=526, Percent_Identity=25.4752851711027, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71993870, Length=566, Percent_Identity=33.9222614840989, Blast_Score=275, Evalue=7e-74,
Organism=Caenorhabditis elegans, GI71993878, Length=328, Percent_Identity=36.890243902439, Blast_Score=184, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6323934, Length=573, Percent_Identity=31.239092495637, Blast_Score=249, Evalue=7e-67,
Organism=Drosophila melanogaster, GI20129809, Length=566, Percent_Identity=30.3886925795053, Blast_Score=251, Evalue=9e-67,
Organism=Drosophila melanogaster, GI24651977, Length=469, Percent_Identity=31.7697228144989, Blast_Score=231, Evalue=9e-61,
Organism=Drosophila melanogaster, GI24653722, Length=564, Percent_Identity=28.1914893617021, Blast_Score=221, Evalue=8e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 64724; Mature: 64724

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENEELIKQVTEKAEKWLTPAYDAETQAEIKKMLANPDKTDLIEAFYKDLEFGTGGLRGI
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHH
MGVGSNRMNIYTVGAATQGLSNYLNKNFKDLDQISVVVGHDCRNNSRLFAEISANIFSAN
HCCCCCCEEEEEECCHHHHHHHHHCCCCCCHHHEEEEECCCCCCCCEEEEEEECCEEECC
GIKVYLFEDMRPTPEMSFAIRHFGCQSGINITASHNPREYNGYKAYWDDGAQVLAPHDKG
CEEEEEEECCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCEEECCCCCC
IIDEVNKISSATDIKFEGNKDLIQIVGEEVDSVYLNKVKTISIDPEVIKRQKDLKIVYTP
HHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHCCEEEEECCHHHHHCCCCCEEEEEE
IHGTGMMLIPRALKQWGFENVHTVPEQMVKSGDFPTVVSPNPENAEALSMAIDLAKKIDA
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCC
DIVMASDPDADRVGMACKNDKGEWVLINGNQTCLLFLYYIIKNRIAMGKMKDDDFIVKTI
CEEEECCCCHHHCCCEEECCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
VTTELIKSVADKNHIEMLDCYTGFKWIAREIRLREGKQQYIGGGEESYGFLAEDFVRDKD
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHCCHH
AVSACTLLAEICAWAKDQGKTLFEVLLDIYVEYGFSKETTVNVVKPGKSGAEEIKAMMEN
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHH
FRSNPPREIGGSKVVLVKDFKTLKVTDGNGNITEIDMPEASNVLQYFTEDGTKISVRPSG
HHCCCCHHCCCCEEEEEECCEEEEEECCCCCEEEECCCCHHHHHHHHHCCCCEEEEECCC
TEPKIKFYVEVKGEMGCHKCFDAANAAAEEKVEAVRKSLGI
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENEELIKQVTEKAEKWLTPAYDAETQAEIKKMLANPDKTDLIEAFYKDLEFGTGGLRGI
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHH
MGVGSNRMNIYTVGAATQGLSNYLNKNFKDLDQISVVVGHDCRNNSRLFAEISANIFSAN
HCCCCCCEEEEEECCHHHHHHHHHCCCCCCHHHEEEEECCCCCCCCEEEEEEECCEEECC
GIKVYLFEDMRPTPEMSFAIRHFGCQSGINITASHNPREYNGYKAYWDDGAQVLAPHDKG
CEEEEEEECCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCEEECCCCCC
IIDEVNKISSATDIKFEGNKDLIQIVGEEVDSVYLNKVKTISIDPEVIKRQKDLKIVYTP
HHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHCCEEEEECCHHHHHCCCCCEEEEEE
IHGTGMMLIPRALKQWGFENVHTVPEQMVKSGDFPTVVSPNPENAEALSMAIDLAKKIDA
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCC
DIVMASDPDADRVGMACKNDKGEWVLINGNQTCLLFLYYIIKNRIAMGKMKDDDFIVKTI
CEEEECCCCHHHCCCEEECCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
VTTELIKSVADKNHIEMLDCYTGFKWIAREIRLREGKQQYIGGGEESYGFLAEDFVRDKD
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHCCHH
AVSACTLLAEICAWAKDQGKTLFEVLLDIYVEYGFSKETTVNVVKPGKSGAEEIKAMMEN
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHH
FRSNPPREIGGSKVVLVKDFKTLKVTDGNGNITEIDMPEASNVLQYFTEDGTKISVRPSG
HHCCCCHHCCCCEEEEEECCEEEEEECCCCCEEEECCCCHHHHHHHHHCCCCEEEEECCC
TEPKIKFYVEVKGEMGCHKCFDAANAAAEEKVEAVRKSLGI
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 2127799 [H]